scholarly journals Drug utilization study of antihypertensive drugs in a tertiary care hospital

2018 ◽  
Vol 7 (12) ◽  
pp. 2309
Author(s):  
A. R. Radhika
Keyword(s):  
Drug Therapy ◽  
Tertiary Care Hospital ◽  
Antihypertensive Drugs ◽  
Generic Drugs ◽  
Tertiary Care ◽  
National Committee ◽  
Common Disease ◽  
Care Hospital ◽  
Cross Sectional ◽  
Number Of Patients

Background: Hypertension is a major common disease and effects a million of people worldwide. And is risk factor for other diseases like cardiovascular diseases, stroke etc. The aim of our study was undertaken to study the utilization pattern of anti hypertensive drugs at a tertiary care hospital. The guidelines for the treatment of hypertension are put forward by the Joint National Committee (JNC) on detection, evaluation and treatment of blood pressure. The Indian guidelines endorsed by the cardiology society of India, the hypertension society of India, and Indian college of physicians closely follow the JNC guidelines.Methods: A prospective cross-sectional observational study was conducted on 100 patients in outpatient Department of General medicine of Government General Hospital, Mahabubnagar district, Telangana. The data collected was analysed from the prescription pattern of anti hypertensive drugs. The data collected were statistically analysed and presented as counts and percentages.Results: Out of 100 study subjects, males were 55% and females were 45% and maximum number of patients in age group are (51 to 60 years.). Among antihypertensive drugs commonly used in present study are Losartan (ARB’s)-64% and for two drug therapy are enalapril and amlodipine 22% and for three drug therapy are enalapril +atenolol+furosemide-14%. Average number of drugs prescribed is 6.15% per prescription. Percentages of medicines prescribed by generic drugs are85% and from the essential drug list are 95%.Conclusions: In this study usage of anti hypertensive drugs were prescribed rationally in tertiary care hospital. The study emphasizes that need for effective continuing medical education and also preventive measures in hypertensive individuals.

scholarly journals Prospective study on prescribing pattern of antihypertensive drugs at a tertiary care hospital

2018 ◽  
Vol 7 (11) ◽  
pp. 2126
Author(s):  
Vishwanath M. ◽  
Murgesh J. V. ◽  
Arpitha D. ◽  
Nithiya D.
Keyword(s):  
Drug Therapy ◽  
Tertiary Care Hospital ◽  
Antihypertensive Drugs ◽  
Tertiary Care ◽  
Care Hospital ◽  
Prescribing Pattern ◽  
Case Record ◽  
Health Maintenance ◽  
Number Of Patients ◽  
Wide Range

Background: Hypertension is the leading non-communicable disease risk attributing to cardio vascular morbidity and mortality. Various reasons are socio-economic, behavioural, sedentary life style, nutritional, age, obesity and poor health maintenance. A wide range of antihypertensive drugs belonging to different pharmacological classes are available alone or in combinations. Present study was done to evaluate the prescribing pattern of antihypertensive drugs at a tertiary care hospital.Methods: A prospective, observational, non-interventional, hospital-based study was carried out in hypertensive patients attending outpatient department of General Medicine at Medical College Hospital attached to Vijayanagar Institute of Medical Sciences, Ballari. Data was collected from outpatient slip of patients in a predesigned case record form, which was analysed using descriptive statistics.Results: Among 200 patients analysed 95 (47.5%) were males and 105 (52.5%) were females, with maximum number of patients falling in the age group 61-70years. Among antihypertensives prescribed, amlodipine (78.5%) was most frequently prescribed drug. Frequently used drugs for monotherapy - amlodipine (37.5%), for two drug therapy - amlodipine + atenolol (25.5%), and for three drug therapy - amlodipine + atenolol + telmisartan (2.5%). WHO prescribing indicators: Average number of drugs per encounter is 2.38 (±1.19). Percentage of drugs prescribed by generic name is 76.47%. Percentage of drugs prescribed from essential drug list is 97.89%.Conclusions: Present study shows current trends in prescription of antihypertensives in tertiary care hospital and their rational use. Study emphasizes need for preventive and educative measures about hypertension in population.

scholarly journals Management Strategy of Patients Attending at Epilepsy Clinic in a Tertiary Care Hospital of Bangladesh

2020 ◽  
Vol 6 (1) ◽  
pp. 3-8
Author(s):  
Mohammad Sayeed Hassan ◽  
Md Shafikul Islam Khan ◽  
Paritosh Kumar Sarkar ◽  
Anwar Israil ◽  
Ferdous Ara ◽  
...  
Keyword(s):  
Partial Seizure ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Partial Epilepsy ◽  
Absence Seizure ◽  
Care Hospital ◽  
Cross Sectional ◽  
Tonic Seizure ◽  
Number Of Patients ◽  
Generalized Epilepsy

Background: Epilepsy is a neuronal disorder that is observed globally but still it is not explored very well in most parts of the world. Objective: The aim of our study was to determine the types of epilepsies along with their treatment strategies among patients attending the outdoor epilepsy clinic in a referral tertiary care hospital. Methodology: This cross sectional study was carried out from the records of weekly epilepsy clinic of Department of Neurology at National Institute of Neurosciences and Hospital, Dhaka, Bangladesh from January 2018 to August 2019. Data were collected through a predesigned questionnaire containing information about demography, clinical features, EEG and imaging findings and treatment of patients. Results: A total number of 1832 patients were recruited. There was a male (55.3%) and urban (61.1%) predominance. Most (75.1%) of the patients were young (age range from 10 to 29 years). A large number of patients were student (44.4%) and 24.2% were unemployed. The duration of epilepsy in most patients were less than 5 years (40.7%). 58.3% patients took various forms of indigenous treatment prior to attending this clinic. 54.7% patients had no comorbid illness. EEG was abnormal in 34.5% patients of which 24.4% had focal abnormality and 10.1% had generalized epileptic discharge. In brain imaging (CT/MRI) only 16.4% showed abnormal findings. 49.5% patients were suffering from generalized epilepsy whereas 44.6% had partial epilepsy. Among the generalized epilepsy group, most of them had generalized tonic clonic seizure (GTCS) (75.4%), while 8.9% had absence seizure and 7.9% had tonic seizure. In partial epilepsy group, the majority were secondary generalized seizure (74.7%), followed by complex partial seizure (CPS) (18.7%) and simple partial seizure (6.6%).42.7% patients got single antiepileptic drug whereas 37.4% patients received dual drug. Polytherapy (three or more drugs) were prescribed in 14% patients. Valproic acid was the highest prescribed drug (29.3%) either as monotherapy or in combination. Carbamazepine (27.4%) was the second common drug followed by Levetiracetam (15.1%). Conclusion: Epilepsy affects almost all groups of the society. Most of the patients remain seizure-free with judicious anti-epileptic drugs. Therefore, more effort is needed for early accurate diagnosis and appropriate treatment of epilepsy Journal of National Institute of Neurosciences Bangladesh, 2020;6(1): 3-8

scholarly journals An Audit of Rational Use of Antibiotics in a Tertiary Hospital

2014 ◽  
Vol 2 (2) ◽  
pp. 64-67 ◽  
Author(s):  
Tanzima Begum ◽  
Md Ismail Khan ◽  
Shamima Kawser ◽  
Md Ehsanul Huq ◽  
Nadira Majid ◽  
...  
Keyword(s):  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Antibiotic Use ◽  
Tertiary Hospital ◽  
Cross Sectional Study ◽  
Care Hospital ◽  
Cross Sectional ◽  
Medical College ◽  
Number Of Patients ◽  
Rational Use Of Antibiotics

Background: Drug can cure ailment when used rationally on the other hand they may become harmful or even may threaten a life when used irrationally. Absence of guidelines for antibiotic use, protocols for rational therapeutics and infection control committees, have led to overuse and misuse of antimicrobials even in different specialized units in hospitals. Objective: The study has been designed to get a picture of use of antibiotics in a tertiary care hospital of Bangladesh. Materials and method: Cross sectional study was conducted in the department of Medicine of Sir Salimullah Medical College and Mitford Hospital, Dhaka, Bangladesh, for 3 months from 1st January 2009 to 31st March 2009. Admitted patients of Medicine unit-1 who got antibiotics were included in the study. Total number of patients was 1563. Results: Five hundred out of 1563 patients were prescribed antibiotics (38%). Out of 500 prescriptions, 68(14%) prescriptions were found irrational. Conclusion: Continuous surveillance should be carried out to reduce the irrational use of antibiotics. DOI: http://dx.doi.org/10.3329/dmcj.v2i2.20526 Delta Med Col J. Jul 2014; 2(2): 64-67

scholarly journals Pattern of use of anti-hypertensive drugs amongst hypertensive patients in a tertiary care hospital: a cross sectional, observational study

2019 ◽  
Vol 9 (1) ◽  
pp. 89
Author(s):  
Sharmin Khan ◽  
Ram N. Maiti ◽  
Sekhar Mandal
Keyword(s):  
Observational Study ◽  
Calcium Channel ◽  
Treatment Guidelines ◽  
Antihypertensive Drugs ◽  
Tertiary Care ◽  
Renal Diseases ◽  
National Committee ◽  
Care Hospital ◽  
Cross Sectional ◽  
Hypertensive Patients

Background: Hypertension is one of the primary modifiable risk factors for cardiac and renal diseases and is the single most important risk factor for stroke. Despite different guidelines for management of hypertension like Joint National Committee, British Hypertension Society, National Institute for Health and Care Excellence; there are still the clouds of controversy. The objective of the study was to evaluate the prescribing pattern of antihypertensive drugs among the patients attending medicine outpatient department of a tertiary care teaching hospitalMethods: A cross-sectional, observational study was conducted in our hospital over a period of six months. Relevant information was collected from medical records of 209 hypertensive patients fulfilling inclusion criteria. The collected data were sorted and analyzed.Results: Out of 209 patients, maximum were of age group of 45-65 years (55.02%). 115 (55.02%) were male and 94 (44.97%) were female. Diabetes mellitus (24.4%) was the most common associated disease with hypertension. Most of the patients had received single antihypertensive drugs (49.28%). Among the monotherapy category calcium channel blocker (82.78%) was the most commonly prescribed antihypertensive drug class followed by angiotensin receptor blocker (36.36%). Amlodipine (81.82%) was the most common among calcium channel blockers. The most frequent fixed drug combination prescribed consisted of amlodipine and atenolol. Most of the drugs were prescribed in generic name (90.9%).Conclusions: The treatment pattern, in general, conformed to standard treatment guidelines.

scholarly journals Needs assessment of resuscitative endovascular balloon occlusion of the aorta (REBOA) in patients with major haemorrhage: a cross-sectional study

2021 ◽  
pp. emermed-2020-210808
Author(s):  
Bård Neuenkirchen Godø ◽  
Jostein Rodseth Brede ◽  
Andreas Jorstad Krüger
Keyword(s):  
Needs Assessment ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Cross Sectional Study ◽  
Balloon Occlusion ◽  
Care Hospital ◽  
Sectional Study ◽  
Cross Sectional ◽  
Number Of Patients ◽  
Endovascular Balloon Occlusion

BackgroundResuscitative endovascular balloon occlusion of the aorta (REBOA) can be used as an adjunct treatment in traumatic abdominopelvic haemorrhage, ruptured abdominal aortic aneurysms, postpartum haemorrhage (PPH), gastrointestinal bleeding and iatrogenic injuries during surgery. This needs assessment study aims to determine the number of patients eligible for REBOA in a typical Norwegian population.MethodsThis was a retrospective cross-sectional study based on data obtained from blood bank registries and the Norwegian Trauma Registry for the years 2017–2018. Patients who received ≥4 units of packed red blood cells (PRBCs) within 6 hours and met the anatomical criteria for REBOA or patients with relevant Abbreviated Injury Scale codes with concurrent hypotension or transfusion of ≥4 units of PRBCs within 6 hours were identified. A detailed two-step chart review was performed to identify potentially eligible REBOA candidates. Descriptive data were collected and compared between subgroups using non-parametric tests for statistical significance.ResultsOf 804 patients eligible for inclusion, 53 patients were regarded as potentially REBOA eligible (corresponding to 5.7 per 100 000 adult population/year). Of these, 19 actually received REBOA. Among the identified eligible patients, 44 (83%) had a non-traumatic aetiology. Forty-two patients (79%) were treated at a tertiary care hospital. Fourteen (78%) of the REBOA procedures were due to PPH.ConclusionThe number of patients potentially eligible for REBOA after haemorrhage is low, and most cases are non-traumatic. Most patients were treated at a tertiary care hospital. The exclusion of non-traumatic patients results in a substantial underestimation of the number of potentially REBOA-eligible patients.

scholarly journals Prescribing pattern and pharmacoeconomic analysis of antidiabetic drugs

2019 ◽  
Vol 8 (8) ◽  
pp. 1844
Author(s):  
Pardeep Kumar Goyal ◽  
Shalini Arora ◽  
Naveen Mittal ◽  
Bharti Mahajan ◽  
Sandeep Kaushal
Keyword(s):  
Drug Therapy ◽  
Pharmacoeconomic Analysis ◽  
Tertiary Care ◽  
Cross Sectional Study ◽  
Antidiabetic Drugs ◽  
Care Hospital ◽  
Prescribing Pattern ◽  
Cross Sectional ◽  
Number Of Patients ◽  
Dual Drug

Background: Diabetes Mellitus is a worldwide growing problem causing threat to patient's health because of its association with various complications and comorbidities. It is a chronic disease requiring lifelong medication which further adds to the economic burden. The objective of this study was to evaluate the prescribing pattern and to do pharmacoeconomic analysis of prescribed antidiabetic drugs.Methods: This observational cross sectional study was conducted for 12 months duration in Outpatient Pharmacy of tertiary care hospital. Prescriptions with antidiabetic drugs were captured and evaluation of prescribing pattern along with pharmacoeconomic analysis of antidiabetic drugs was done.Results: A total of 611 prescriptions with antidiabetic drugs were analyzed. There were total 4034 drugs in all prescriptions with a mean of 6.6 drugs per prescription. 4.28% of drugs were prescribed by generic name and 58.9% of prescribed drugs were from essential drug list. Dual drug therapy was prescribed in maximum number of patients (42.2%) followed by monotherapy (28.8%). More commonly prescribed class of antidiabetic drugs was biguanides as monotherapy (n=119) and its combination with sulfonylureas was prescribed maximally among dual drug therapy (n=158). Cost of monthly therapy for antidiabetic drugs prescribed as monotherapy was least with Biguanides (₹ 98.89/ month) whereas combination of biguanides and thiazolidinediones was least expensive among dual drug therapy (₹ 216/ month).Conclusions: Biguanides was the most common prescribed class of antidiabetic drugs among monotherapy and its combination with sulfonylureas was most prescribed as dual drug therapy and both of these therapies were economical.

scholarly journals Study of association between characteristics of patient and likelihood of benzodiazepine use in psychiatry outpatient department at tertiary care hospital of Kathmandu

2017 ◽  
Vol 7 (3) ◽  
pp. 13-20
Author(s):  
Binod Raut ◽  
Anjan Khadka ◽  
Pradeep Manandhar ◽  
Kamal Kandel
Keyword(s):  
Drug Therapy ◽  
Tertiary Care Hospital ◽  
Muscle Relaxation ◽  
Tertiary Care ◽  
Study Drug ◽  
Developed Countries ◽  
Outpatient Department ◽  
Care Hospital ◽  
Cross Sectional ◽  
Benzodiazepine Use

Introduction: Benzodiazepines exert their pharmacological properties as hypnotics, anxiolytics, anticonvulsants and muscle relaxants. Benzodiazepines are clinically effective for a number of indication including the reduction of anxiety, the induction and maintenance of sleep, muscle relaxation. They have a range of well documented adverse effects that may outweigh the benefits in certain patient population including psychomotor impairment, development of tolerance and dependence, potential for abuse. Methods: It is a hospital based prospective cross-sectional study conducted in a psychiatry outpatient department of tertiary care hospital. All the patients attended to the outpatient department of psychiatry and prescribed with benzodiazepine were selected for study. Drug therapy details in medication chart review and clinical review in patients treated with benzodiazepines was analyzed to measure the utilization pattern of benzodiazepines in terms of patient characteristics (e.g. age, gender and marital status), occupation, education and diagnosis, number of prescription of benzodiazepines, their doses, frequency, routes of administration and duration of use in each patient. Results: Out of a total of 384 patients, 246 of the patients had been currently using at least one benzodiazepine. Prevalence of benzodiazepine use was 64%. There was statistically significant association between benzodiazepines use with gender distribution, occupation and education. The prevalence of benzodiazepines use is relatively higher than that reported in the developed countries. Clonazepam was the most widely used benzodiazepine followed by lorazepam. Conclusion: The study evaluated the association between characteristics of patient and likelihood of benzodiazepines use. This will definitely help to optimize the drug therapy, improve the quality of care and reduce the negative outcomes in the usage of benzodiazepines.

scholarly journals Colposcopic Findings among VIA Positive Women: Experience at a Tertiary Care Hospital

2014 ◽  
Vol 1 (1) ◽  
pp. 8-12
Author(s):  
Farzana Rabee Choudhury ◽  
ABM Zakir Uddin ◽  
M Abdullah Yusuf
Keyword(s):  
Tertiary Care Hospital ◽  
Screening Program ◽  
Tertiary Care ◽  
Cross Sectional Study ◽  
Care Hospital ◽  
Cross Sectional ◽  
Medical College ◽  
Number Of Patients ◽  
The Status ◽  
Cervical Cancer Screening Program

Background: Visual inspections of the cervix after acetic acid application (VIA) are widely recommended as the method of choice in cervical cancer screening program in resource-limited settings.Objective: The purpose of the present study was to see the status of VIA test result at a tertiary care hospital. Methodology: This cross sectional study was carried out at Shaheed Suhrawardy Medical College, Dhaka and Dhaka Medical College, Dhaka from April 2012 to March 2013 for a period of one year. VIA was performed and colposcopy was done among the VIA positive patients.Results: A total number of 65 VIA positive patients were evaluated colposcopically In all VIA positive patients, colposcopically positive was in 47.7% cases. Among colposcopically positive patients CIN-I was 27.69%; CIN-II was 18.46% and CIN-III was 1.54%. Conclusion: VIA test is positive in a high number of patients which has a great number of abnormalities were found.DOI: http://dx.doi.org/10.3329/jcamr.v1i1.19559J Curr Adv Med Res 2014;1(1):8-12]

Assessment of Daily Burden and Factors for Overcrowded Emergency Department at Tertiary Care Hospital of Karachi

2021 ◽  
pp. 30-35
Author(s):  
Arsala Faridi ◽  
Farah Ahmad ◽  
Areej Zehra ◽  
Afreen Fazal
Keyword(s):  
Emergency Department ◽  
Emergency Room ◽  
Tertiary Care Hospital ◽  
Patient Flow ◽  
Tertiary Care ◽  
Care Hospital ◽  
Cross Sectional ◽  
Study Duration ◽  
Number Of Patients ◽  
Significant Difference

Background: When in emergency room there is no enough area left to serve or to admit the subsequent sick patients who may require urgent attention and observation the setting is called as the overcrowded emergency room. Due to overcrowded emergency department the quality of services provided by the staff and doctors is compromised ultimately patients with severe diseases are ignored and this may be one of the causes for causalities. Objective: To assess the daily burden and factors responsible for overcrowding at emergency department of tertiary care hospital of Karachi. Methodology: It was a cross sectional study conducted at tertiary care hospital of Karachi from October 2020 to January 2021. Data of patients coming to adult emergency department of either gender were collected.  Patients age <14 were excluded as these were referred to pediatric emergency department. Data collection was done according to Canadian emergency department triage and acuity scale (CTAS). Results: Total number (N) of patients who visited emergency department in study duration was 13434. The mean number of patients who visited ED was 141±13during our study duration. There was no any significant difference in presenting complaint. Delay in investigations was found to be a reason of prolong stay and overcrowding in ED in our setting. Conclusion: Overcrowding of patients in our ED of our setting was a common problem. The number of staff, doctors and beds were not matching the number of patient flow in the department. The main reason of prolong stay in ED was delay in investigations.

scholarly journals TO STUDY PRESCRIPTION PATTERN IN THE MANAGEMENT OF OSTEOARTHRITIS IN TERTIARY CARE HOSPITAL

2020 ◽  
pp. 87-92
Author(s):  
SHRIKANT B LAHAMATE ◽  
SYED U RAZVI
Keyword(s):  
Risk Factor ◽  
Drug Therapy ◽  
Combination Therapy ◽  
Old Age ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Common Disease ◽  
Case Report Form ◽  
Care Hospital ◽  
Prescription Pattern

Objective: The leading cause of disability is arthritis among adults worldwide. Osteoarthritis (OA) is the most common form of joint disease and the leading cause of pain in elderly people. The aim of the study was to study the prescription pattern in the management of OA. Methods: A prospective observational study was conducted in a tertiary care hospital for period of 12 months in collaboration with the department of orthopedics. A total of 630 patients enrolled in the present study with fulfilling inclusion and exclusion criteria. Patients’ data recorded in case report form and analyzed to study the prescription pattern. Results: A total of 630 cases were enrolled in this study. Osteoarthritis is more common in female i.e. 55% followed by male i.e. 45% of patients. Old age (39.84%) is most common risk factor followed by obesity (29.68%) in OA patient. Most commonly prescribed drug was diclofenac followed by paracetamol. Nonsteroidal anti-inflammatory drugs were most commonly prescribed class of drug, i.e., 92.19%. In this study, combination therapy most commonly prescribed, i.e., 75.4% followed by monotherapy, i.e., 24.6%. Combination therapy in OA patients two drug therapy, i.e., 88.42% followed by three drug therapy, i.e., 10.53%. Conclusions: The principal aim of drug utilization research is to facilitate the rational use of drugs. The study shows that OA more common in female patient than male patient. The most common disease distribution site was knee in OA patient. Old age was the most common encounter risk factor in OA patient. Combination therapy was most commonly used than single drug therapy.

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