scholarly journals Prescription audit and drug utilization pattern in outpatients of psychiatry department of tertiary care teaching hospital: an observational study

2019 ◽  
Vol 8 (2) ◽  
pp. 222
Author(s):  
Angelika Batta ◽  
Pushpawati Jain ◽  
Bhupinder Kalra
Keyword(s):  
Observational Study ◽  
Psychotropic Drugs ◽  
Tertiary Care ◽  
New Drugs ◽  
Essential Medicines ◽  
Fixed Dose ◽  
Potential Hazard ◽  
Care Hospital ◽  
Inappropriate Use ◽  
Prescribing Trends

Background: The domain of psychiatric illnesses is grossly underrepresented in the current health care scenario especially due to overreliance on mortality rather than the morbidity or dysfunction. The field of psycho-pharmacology is witnessing constant development and introduction of new drugs for which holistic utilization, effectiveness, and side effects studies are the need of the hour. In addition, inappropriate use of drugs poses a potential hazard to patients. Our current study aims at studying the morbidity pattern of various psychiatric ailments and focuses on the prescribing trends of psychotropic drugs.Methods: A prospective observational study was conducted in psychiatry out-patient department of a tertiary care hospital for a period of 12 months. Prescription pattern of psychotropic drugs was analyzed using predesigned format. Prescriptions were collected from OPD and hospital pharmacy. Prescriptions were analysed as per WHO indicators for prescriptions. Descriptive statistics were used for analysis.Results: Depression was found to be the most common psychiatric disorder encountered (32.6%). Average number of psychotropic drugs prescribed per patient 2.45±1.013. Antidepressants along with BZD were the most frequently prescribed psychotropic drugs in various psychiatric disorders. Among the total of 2445 psychotropic drugs prescribed, 99.98% were oral formulations. Psychotropic fixed dose combinations were present in 1.68% of the prescriptions. Only 28% of medicines were prescribed by generic names. Utilization of drugs from the WHO’s 18th list of essential medicines of India was 29%. PDD of risperidone was 1.57mg in schizophrenia. Escitalopram, resperidone and propranolol were the most commonly prescribed drugs for mood disorders, schizophrenia and anxiety respectively.Conclusions: The concomitant use of two psychotropic drugs was the preferred therapy. FDC of anti-cholinergics with both typical and atypical antipsychotics were used. Benzodiazepins were significant part of therapy.

scholarly journals Chemotherapy-Associated Pulmonary Toxicity—Case Series from a Single Center

2021 ◽  
Author(s):  
Tilak TVSVGK ◽  
Ajay Handa ◽  
Kishore Kumar ◽  
Deepti Mutreja ◽  
Shankar Subramanian
Keyword(s):  
Observational Study ◽  
Pulmonary Toxicity ◽  
Imaging Finding ◽  
Tertiary Care ◽  
Case Series ◽  
Fiberoptic Bronchoscopy ◽  
Chemotherapeutic Agents ◽  
New Drugs ◽  
Care Hospital ◽  
Persistent Symptoms

Abstract Background Pulmonary toxicity due to chemotherapeutic agents can occur with many established and new drugs. Strong clinical suspicion is important as the clinical presentation is usually with nonspecific symptoms like cough, dyspnea, fever, and pulmonary infiltrates. Timely discontinuation of the offending agent alone can improve the condition. Methods A prospective observational study on patients receiving chemotherapy at an 800-bedded tertiary care hospital was performed from 2014 to 2016. Consecutive patients on chemotherapy, presenting with nonresolving respiratory symptoms were evaluated with contrast-enhanced computerized tomography of chest, diffusion lung capacity for carbon monoxide (DLCO), fiberoptic bronchoscopy with lavage, and biopsy, after excluding all causes for pulmonary infections. Descriptive data has been depicted. Results A total of 18 patients were evaluated for persistent symptoms of dry cough, dyspnea, and fever among 624 who received chemotherapy during the study period. Ground-glass opacities on high-resolution CT was the most common imaging finding, others being patchy subpleural consolidation and pleural effusion. Lymphocyte-predominant bronchoalveolar lavage was detected in nine. Eight of the 15 patients who underwent DLCO, had abnormal results. Seven had significant histopathological findings on bronchoscopic lung biopsy, which revealed organizing pneumonia as the most common pattern. Paclitaxel, fluorouracil, gemcitabine, and tyrosine kinase inhibitors were the common culprit drugs. Discontinuation alone of the culprit drug was effective in 15 and 3 needed oral corticosteroids for relief of symptoms. None of the patients died due to the toxicity. Conclusion An incidence of 2.8% for chemotherapy-induced lung injury was seen in our observational study of 3 years, with parenchymal, interstitial, and pleural involvement due to various chemotherapeutic agents. Oral steroids maybe required in a subset of patients not responding to discontinuation of the culprit agent.

PRESCRIPTION PATTERN OF PSYCHOTROPIC DRUGS IN A PSYCHIATRY OPD OF A TERTIARY CARE HOSPITAL – A CROSS SECTIONAL STUDY.

2021 ◽  
pp. 191-194
Author(s):  
Kishore M S ◽  
Narendra Kumar ◽  
S Sindhu
Keyword(s):  
Psychotropic Drugs ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Cross Sectional Study ◽  
World Health ◽  
Fixed Dose ◽  
Care Hospital ◽  
Sectional Study ◽  
Cross Sectional ◽  
Prescription Pattern

Background: The expanding and challenging eld of psychopharmacology is constantly seeking new and improved drugs to treat psychiatric disorders. Psychotropic drugs utilization in actual clinical practice, effectiveness and safety in the real-life situation needs continuous study. Therefore, the study was undertaken to analyze the prescription pattern of psychotropic drugs. Methods: A Cross sectional study was conducted in the psychiatry out-patient department of a tertiary care hospital for 4 months. Diagnosis was made according to ICD-10 criteria. Prescription pattern was analyzed using World Health Organization (WHO) drug indicators. Results: Psychotropic drugs constituted 74.85% of the prescribed medication. Average number of the psychotropic drugs per prescription was 2.53. Percentage of prescriptions with injectable drugs accounted for 5.13%. 59.28% of the drugs were prescribed by generic names, while the rest were branded. 28% of prescriptions contained psychotropic FDCs (Fixed dose th combination). 78.65% of the drugs were from the WHO's 18 List of Essential Medicines. Among the total psychotropic drugs prescribed, antipsychotics (43.87%) were the most commonly prescribed class of drugs followed by antidepressants (23.32%), anxiolytics (22.13%) and the mood stabilizers (9.88%) were the least. Conclusions: Prescription pattern of the psychotropic drugs were in accordance to the recommendations of various treatment guidelines. Antipsychotics were the most commonly prescribed psychotropic drugs.

scholarly journals Drug utilization of antibiotics in post-operative cesarean section inpatients in tertiary care hospital: a prospective observational study

2020 ◽  
Vol 9 (6) ◽  
pp. 859
Author(s):  
Srinivasa B. ◽  
Basavaraj C. Kotinatot
Keyword(s):  
Caesarean Section ◽  
Observational Study ◽  
Prospective Observational Study ◽  
Tertiary Care ◽  
Essential Medicines ◽  
Care Hospital ◽  
Cross Sectional ◽  
Institutional Ethics ◽  
National Model ◽  
Rational Use Of Antibiotics

Background: The aim of this study is to evaluate the pattern and rational use of antibiotics in post-operative caesarean section (CS) inpatients in tertiary care teaching hospital, BIMS Belagavi.Methods: This cross sectional prospective observational study was conducted from December 2019 to February 2020, prior permission from institutional ethics committee was taken. Detailed data of post-operative caesarean section (CS) inpatients including age, diagnosis, line of management, complications and any adverse effects if occurred during the study was collected and entered in a specially designed proforma and MS word excel and analyzed by descriptive statistics like percentage.Results: Total 100 post-operative caesarean section inpatients were involved in the study. Most common indication for C-section was cephalopelvic disproportion. Average no of antibiotics per prescription was 3.32. Most commonly prescribed antibiotic was cefotaxime (27.71%) followed by gentamycin (25.90%) and metronidazole (24.59%). Majority (90%) of patients who admitted for ≤3 days (66%) had received combination antibiotic i.e., cefotaxime, metronidazole and gentamycin. IV fluids (21.21%) and analgesics (13.13%) were most frequently prescribed concomitant drugs. Majority (97.8%) of patients received parenteral preparation. 306 antibiotics (92.17%) used were from national model list of essential medicines (NLEM) and 332 antibiotics (100%). used were by generic name. Polypharmacy was 7.92.Conclusions: Cefotaxime was the most frequently prescribed antibiotic. Most of the antibiotics prescribed was rationally from NLEM and were by generic name.

scholarly journals Pattern of Cardiovascular Drugs Use in Outpatient Department in a Tertiary Care Hospital of Bangladesh

2018 ◽  
Vol 32 (2) ◽  
pp. 65-69
Author(s):  
Udoy Shankar Roy ◽  
AKM Monwarul Islam ◽  
Mohsin Ahmed ◽  
Murshidur Rahman Khan ◽  
Nihar Ranjan Sarker
Keyword(s):  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Cardiovascular Drugs ◽  
Medical College Hospital ◽  
Outpatient Department ◽  
Essential Medicines ◽  
Fixed Dose ◽  
Care Hospital ◽  
College Hospital ◽  
Medical College

Objective: The objective of the present study was to provide recent population-based information on use of cardiovascular drugs in outpatients in a tertiary care hospital of Dhaka, Bangladesh.Methods: A prospective study of cardiovascular prescriptions of Outpatient Department of Department of Cardiology of Shaheed Suhrawardy Medical college hospital Dhaka, Bangladesh was carried out. A total of 215 prescriptions were collected for the study in Shaheed Suhrawardy Medical College Hospital Dhaka, Bangladesh from July 2015 to June 2016. The prescriptions were evaluated for rationality based on WHO model list of essential medicines. The prescriptions were critically analyzed using predetermined parameters.Results: Out of 215 prescriptions collected, 120 drugs were found to be repeatedly prescribed. The results revealed that all single dose formulations prescribed were rationally in accordance with WHO essential drug list whereas fixed dose combinations prescribed remain questionable. A pattern of polypharmacy was clearly evident.Conclusion: Medications are a critical modality for prolongation and improved quality of life. Campaign and intervention should be focused on patients with more than three diagnostic cardiovascular conditions in order to minimize polypharmacy in patients particularly elderly.Bangladesh Heart Journal 2017; 32(2) : 65-69

scholarly journals Prescribing trends of anti glaucoma medication usage in treatment naive patients of primary open angle glaucoma in a tertiary care hospital in Eastern India

2018 ◽  
Vol 7 (5) ◽  
pp. 971
Author(s):  
Aditi Maitra ◽  
Shashwat Bhattacharyya ◽  
Shatavisha Mukherjee ◽  
Nikhil Era ◽  
Sambuddha Ghosh ◽  
...  
Keyword(s):  
Primary Open Angle Glaucoma ◽  
Treatment Guidelines ◽  
Open Angle Glaucoma ◽  
Tertiary Care ◽  
Fixed Dose ◽  
Care Hospital ◽  
Open Angle ◽  
Entire Study ◽  
Prescribing Trends ◽  
Treatment Naïve

Background: Primary open angle glaucoma remains a high magnitude healthcare problem due to its prevalence and chronicity. The real world scenario of anti glaucoma medical therapy needs periodical auditing as far as drug prescriptions are concerned for formulation of treatment guidelines. Few studies from India have taken a longitudinal approach in this respect. This study was undertaken to identify such lacunae.Methods: This was an open label, prospective, observational study. Each treatment naive patient was followed up for a period of 6 months, where their prescriptions were scanned for the type of the anti glaucoma medications, total number of medications, route of administration, their duration of use and their frequency of dosage and change in medications if any, in each visits.Results: A gradual shift from monotherapy towards combination therapy was observed. Overall averages for prescriptions were topped by monotherapy at 44.25 followed by fixed dose combinations at 38.25, and then combination-polytherapy at 36 and the least number of prescriptions were for concurrent polytherapy at 17.5. Amongst all monotherapy agents, beta blockers were the most frequently prescribed drugs at baseline but their share of prescriptions was almost halved at the end of our study. The prostaglandin analogs on the other hand saw an upsurge in prescriptions from their baseline to the end of this study. Prostaglandin analogs andbeta blockers as fixed dose combination was a popular prescription over the entire study duration.Conclusions: Prescribing trends were remarkable for the shift from primary monotherapy towards fixed dose combinations as the study concluded. The decline in the number of beta blocker prescriptions and a rise in prostaglandin analog prescriptions is a testament to their better effectiveness and tolerability. The future of open angle glaucoma pharmacotherapy lies in prescribing more efficacious drugs either in monotherapy or in fixed combinations.

Psychotropic drug utilization in psychiatric outpatient department of a tertiary care teaching hospital in India

2017 ◽  
Vol 5 (4) ◽  
pp. 1612
Author(s):  
Mohanraj Rathinavelu Mudhaliar ◽  
Ishrar Shaik Mohammad Ghouse ◽  
Priyanka Sadubugga ◽  
Swaroop Reddy Narala ◽  
Vidyasagar Chinnakotla ◽  
...  
Keyword(s):  
Psychotropic Drug ◽  
Psychotropic Drugs ◽  
Psychiatric Illness ◽  
Tertiary Care ◽  
Real Life ◽  
Psychotropic Medications ◽  
World Health ◽  
Fixed Dose ◽  
Care Hospital ◽  
Prescribing Pattern

Background: Although psychotropic medications have had a remarkable impact on psychiatric practice that legitimately can be called revolutionary, their utilization and consequences on real life effectiveness and safety in actual clinical practice need continuous study.Methods: The current retrospective study of six months’ duration was designed to assess the utilization of antipsychotics and its prescribing pattern in a tertiary care hospital of south India, which included prescriptions of patients suffering from a psychiatric illness with at least one psychotropic drug of all ages and both sexes.Results: Out of 150 cases reviewed, 46% were of schizophrenia, where male (60.67%) at higher incidence of psychiatric illness, and maximum patients were under the age group of 29-39 years (54.67%). In present study of 355 prescribed drugs 72.67% were psychotropic medications. As per World Health Organization/International Network for Rational Use of Drugs (INRUD) drug use indicators average number of drugs per prescription (2.37%), average number of psychotropic drugs per prescription (1.72%), psychotropic drugs prescribed as Fixed Dose Combinations (FDCs) was 26.36%, and percentage of drugs prescribed by generic name (91.08%). In our study, 48.09% of psychotropic drugs were utilized in the treatment of schizophrenia, diazepam (17.06%) was the only psychotropic medication distributed in the management of all three observed psychiatric disorders and the study showed a higher utilization of psychotropic drugs as FDCs (25.98%) in the management of schizophrenia.Conclusions: The study advocated an overall rational utilization of psychotropic drugs with a fewer deviations due to socio-economic status of patients and prescription practices of healthcare providers. 

scholarly journals Drug utilization study in diabetic patients seeking medical treatment in a north Indian rural medical college hospital

2018 ◽  
Vol 7 (5) ◽  
pp. 912
Author(s):  
Shweta Sharma ◽  
S. C. Chopra ◽  
D. K. Sharma ◽  
Juhi Singla ◽  
Vinod Kapoor
Keyword(s):  
Chronic Disease ◽  
Drug Utilization ◽  
Demographic Data ◽  
Tertiary Care ◽  
General Medicine ◽  
Essential Medicines ◽  
Fixed Dose ◽  
Diabetic Patients ◽  
Care Hospital ◽  
College Hospital

Background: Diabetes Mellitus is a chronic disease and its life-long management causes burden on lifestyle and financial condition of the patients. Drug utilization studies provide useful insights into the current prescribing practices.Methods: To evaluate the drug utilization pattern of anti-diabetic drugs in diabetic patients. A prospective observational study was carried out in adult diabetic patients visiting the Wards and Outpatient Department of General Medicine of a tertiary care hospital. The demographic data and utilization of different classes of anti-diabetic agents as well as individual drugs were analyzed.Results: In 125 patients (Male-65, Female-60), a total of 379 drugs (average 3.032±2.05) were used per day, out of which 76 (20.05%) were rational fixed dose combinations (FDCs) and 261 (68.86%) were prescribed from National List of Essential Medicines (NLEM) 2015. The number of drugs prescribed to be ingested was 326 (86.01%) and 63 (16.62%) were injectables.Conclusions: It was found that the prescription tendencies of the doctors were quite rational. More improvement can be done by sensitizing them to prescribe more drugs from NLEM. The limitations in the affordability of rural population should be taken care of while prescribing drugs for this chronic disease.

scholarly journals Study of utilisation trends of drugs in patients admitted with cardiovascular diseases at a tertiary care hospital in Goa

2017 ◽  
Vol 3 (12) ◽  
pp. 311
Author(s):  
Shantadurga S. Kerkar ◽  
Padma N. Bhandare
Keyword(s):  
Cardiovascular Diseases ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Healthcare Providers ◽  
Cardiovascular Drugs ◽  
Essential Medicines ◽  
Fixed Dose ◽  
Care Hospital ◽  
Mortality And Morbidity ◽  
Essential Drug List

<p class="abstract"><strong>Background:</strong> CVDs have emerged as a leading cause of mortality and morbidity in the world as well as in India. Drug usage is life saving and at times many drugs may be needed. Drug utilization studies aid to find the appropriateness of treatment, identify shortcomings if any, and provide a feedback to the healthcare providers to improve their management with drugs. So such types of studies are of vital importance in every hospital.</p><p class="abstract"><strong>Methods:</strong> This was a prospective, observational study of 180 patients with CVDs admitted in medicine and cardiology wards of a tertiary care hospital, conducted through case records and patients’ interviews. Data was represented as mean±SD, number and frequency.  </p><p class="abstract"><strong>Results:</strong> Incidence of cardiovascular diseases was more in males (56.67%) than the females (43.33%). Average number of drugs prescribed per patient was 9.16 and that of cardiovascular drugs was 5.08 ± 2.15. Antiplatelets (88.88%) were the most commonly prescribed cardiovascular drugs followed by hypolipidemics (82.22%). About 15.06% of injectables and 1.2% of fixed dose combinations (FDCs) were prescribed. Drugs prescribed by generic names were 1.6% and those from the National List of Essential Medicines were 92.79%.</p><p><strong>Conclusions:</strong> The results of this study suggested: polypharmacy, overuse of injections and low prescribing habits from essential drug list. Though antiplatelet, hypolipidemic use was higher, these are an essential part of treatment of certain CVDs. </p>

Sign in / Sign up

Export Citation Format

Share Document