scholarly journals A study of etiology and outcome of preterm birth at a tertiary care centre

2017 ◽  
Vol 6 (10) ◽  
pp. 4488
Author(s):  
Shaveta Garg ◽  
Tajinder Kaur ◽  
Ajayveer Singh Saran ◽  
Monu Yadav
Keyword(s):  
Preterm Birth ◽  
Tertiary Care ◽  
Preterm Births ◽  
Active Phase ◽  
Care Hospital ◽  
Tertiary Care Centre ◽  
Mortality And Morbidity ◽  
High Incidence ◽  
History Of ◽  
Tract Infections

Background: Preterm births are still the leading cause of perinatal mortality and morbidity. It is a major challenge in the obstetrical health care.Methods: This study was conducted over a period of eight months from September 2016 till April 2017 at a tertiary care hospital. All patients who delivered a live baby before 37 weeks of gestation were included in the study.Results: Present study was conducted on 100 eligible women out of which 7 delivered before 30 weeks but majority of them (55%) delivered after 34 weeks of gestation. In our study, most of the patients (66%) presented in active phase of labor which resulted in preterm birth of baby. The most common risk factor of preterm labor was genitourinary tract infections (34%) followed by Preterm Premature rupture of membranes (22%). Past obstetric history of preterm delivery and abortions also had a significant impact on the present pregnancy outcome.Conclusions: Preterm labour and birth still have a high incidence causing significant neonatal mortality and morbidity as well as economic burden on family and hospital. The causes of preterm birth are multifactorial and modifiable. This incidence can be reduced by early identification of established risk factors, as revisited and reemphasized in our study, with the help of universal and proper antenatal care.

scholarly journals Maternal and foetal outcome in preterm births in a rural tertiary care centre: a retrospective study

2021 ◽  
Vol 11 (1) ◽  
pp. 50
Author(s):  
Deeksha Rao M. ◽  
Vasantha Kumar S.
Keyword(s):  
Retrospective Study ◽  
Preterm Birth ◽  
Tertiary Care ◽  
Preterm Births ◽  
Morbidity And Mortality ◽  
Care Hospital ◽  
Tertiary Care Centre ◽  
Mortality And Morbidity ◽  
Medical Disorders ◽  
Nicu Admission

Background: Preterm birth (PTB) is one of the main causes of perinatal mortality and morbidity. It can also result in long term health consequences for both mother and the newborn. The objective was to assess maternal and fetal morbidity and mortality in PTBs.Methods: A retrospective study was done in the department of obstetrics and gynecology in a tertiary care hospital during January 2020 and June 2020. Ninety-three women with records of preterm births were analyzed for maternal and fetal outcomes. coGuide statistical software was used for data analysis.Results: 48.39% of the women were between 20 to 24 years of age. The majority (50.54%) were primigravida. The main causes for PTB among the study participants were medical disorders (39.78%), PPROM (29.03%), spontaneous labor without any underlying cause (18.28%). 51.61% had a vaginal delivery, 88.17% had a live birth. The majority of 52 (55.91%) neonates had birth weights between 1.51 to 2.5 kg. Fifty-nine neonates (63.44%) needed NICU admission. The reason for NICU admission in majority 25 (26.88%) was respiratory distress.Conclusions: Timely, early diagnosis and treatment of medical disorders among antenatal women can aid in reducing the occurrence of preterm births and their associated morbidity and mortality. Medical disorders and premature preterm rupture of membrane remain the main causes of preterm birth. 

scholarly journals Study of risk factors of acute respiratory infections in children admitted in a tertiary care hospital of Southern Maharashtra

2017 ◽  
Vol 4 (9) ◽  
pp. 3129
Author(s):  
Alka C. Kaware ◽  
Nitin H. Kamble ◽  
S. K. Mangulikar
Keyword(s):  
Risk Factors ◽  
Respiratory Infections ◽  
Tertiary Care ◽  
High Morbidity ◽  
Acute Respiratory Infections ◽  
Care Hospital ◽  
Care Centre ◽  
Tertiary Care Centre ◽  
History Of ◽  
Tract Infections

Background: Acute respiratory infections (ARI) is an important cause of mortality and morbidity in children. In India, it constitutes 15% of under five deaths. Various risk factors are responsible for ARI in children. Study of risk factors will help to reduce the high morbidity and mortality due to ARI. The objectives were to study risk factors responsible for acute respiratory infections in children and to find out case fatality rate &/ outcome of acute respiratory infections ARI in children.Methods: A hospital based cross sectional study was done in 2013-14 in a tertiary care centre to study the risk factors associated with ARI in children. All the pediatric patients between 0-12 years admitted in a tertiary care centre at Solapur were enrolled in the study.Results: Acute respiratory tract infections (ARI) were more common in 1-4 years age group i.e. 57.31% (196). It was more common in males i.e. 64.33% (220) than females i.e. 35.67% (122). ARI was more common in lower socio-economic classes i.e. class V (50.58%), class IV (22.52%); in patients whose mothers were illiterate 43.28% and who had history of parental smoking 84.21%. Maximum patients of ARI were having history of overcrowding 75.73%, inadequate cross-ventilation 81.87% and use of smoky chullah 78.65% in their home. Statistically significant association found between ARI cases and these socio-demographic factors. 46.78% (160) were incompletely immunized and 16.37% (56) were not immunized at all. Only 36.84% (126) were completely immunized for their age. Maximum cases of ARI (50.88%) occurred in winter season followed by rainy season (26.90%). Outcome showed that 91.52% (313) were cured, while 1.75% (6) patients died due to ARI.Conclusions: The present study has identified various socio-demographic, nutritional and environmental risk factors for ARI which can be prevented by effective health education and an appropriate initiative taken by the government.

scholarly journals Outcome of moderate preterm and term babies at tertiary care centre

2018 ◽  
Vol 5 (6) ◽  
pp. 2222
Author(s):  
Shaitan Singh Balai ◽  
Durgavati Katara ◽  
Vivek Arora
Keyword(s):  
Gestational Age ◽  
Tertiary Care ◽  
Preterm Births ◽  
Preterm Neonates ◽  
Care Hospital ◽  
Tertiary Care Centre ◽  
Major Morbidity ◽  
Mortality And Morbidity ◽  
Maternal Risk ◽  
Maternal Hypertension

Background: To study the maternal risk factors, morbidity, mortality of moderate preterm in comparison to term neonates.Methods: This Cohort study involved two hundred fifty consecutively born moderate preterm and equal number of term newborns delivered in a tertiary care hospital. They were followed till discharge for morbidities and mortality. Detailed maternal and neonatal factors were studied and compared between the two groups.Results: Moderate preterm babies constituted 55% of all live preterm births during the study period. The odds of babies developing major morbidity was significantly more in those whose mothers had hypertension and infections (OR 2.69 95% CI: 1.55, 4.68 and 2.08, 95% CI: 1.6, 2.71 respectively). In the study group, 42.4% and 20.8% babies suffered major and minor morbidity compared to 8.4% and 6.8% of term controls respectively. moderate preterm neonates had significantly higher odds of developing morbidity like respiratory distress (12.4% vs. 5.6%, OR 2.21, 95%CI 1.21,4.11), need for non-invasive(17.3% vs. 5.7%, OR 3.05 95% CI 1.69, 5.47) and invasive ventilation (14.6% vs. 1.7%, OR 8.62, 95% CI 3.09, 24.04), sepsis (20.8% vs. 5.2%, OR 5.20, 95% CI 2.71, 9.99), seizures (22.8% vs. 4.8%, OR 4.75 95%CI 2.61, 8.63), shock (17.6% vs. 4.4%, OR 4.00 95% CI 2.12,7.56), and jaundice (26% vs. 6%, OR 4.33 95%CI 2.54, 7.39). By logistic regression, the odds of developing major morbidity decreased with increasing gestational age (aOR 0.28 95% CI 0.18, 0.45; p<0.001) and increased with hypertensive disease of pregnancy (aOR 2.16 95% CI 1.09, 4.260; p00.026).Conclusions: Moderate preterm neonates have significantly more mortality and morbidity compared to term controls. Maternal hypertension and lower gestational age are the strongest predictors of morbidity.

scholarly journals Death due to sickle cell anemia: autopsy diagnosis

2017 ◽  
Vol 5 (7) ◽  
pp. 3185
Author(s):  
Manjusha Shripad Dhawle ◽  
Ashwini Radhakrishan Tangde ◽  
Santosh Govind Rathod ◽  
Rajan S. Bindu
Keyword(s):  
Sickle Cell Disease ◽  
Sickle Cell ◽  
Tertiary Care ◽  
Medical Officer ◽  
Clinical History ◽  
Care Hospital ◽  
Cell Disease ◽  
Unexpected Death ◽  
Mortality And Morbidity ◽  
History Of

Background: Sickle cell disease (SCD) is well known and is the commonest hereditary hematological disorder which is associated with increased mortality and morbidity.  They are group of inherited haemoglobinopathies caused by the occurrence of hemoglobin S (Hbs) in homozygous or heterozygous form or in combinations of Hbs with another hemoglobin such as Hbsc or beta thalassaemia (Hbs-thal). Sickle cell syndromes are remarkable for their clinical heterogenecity including their presentations as sudden and unexpected death due to sickle cell crises. While doing autopsy in cases of deaths with no apparent cause and physical over activity medical officer must keep in mind the possibility of death due to vasoocclusive crisis in sickle cell disease. Aim of the study was to create awareness among the physicians and relatives / public and to minimize future unexpected death from complications or crisis from SCD.Methods: This is a retrospective study of 10 cases carried in the department of pathology, in tertiary care hospital and covers a period from January 2009 to December 2016. These cases were brought dead to the casualty with a history of sudden death. After post mortem examination, the specimens were sent for histopathological examination.Results: The record of 10 cases was reviewed. Out of our ten cases 7 were male and 3 were females. The youngest person was 17-year female and oldest was 65 years male. In clinical history 3 cases had complains of chest pain (30%), 3 others had complained of breathlessness (30%), 2 had history of unconsciousness (20%), one case had complained of abdominal pain (10%) and one case had a history of fall and injury (10%). Microscopic examination of each organ was carried out.  Organs like lungs, liver, spleen, kidneys, heart and brain showed wide spread congested vessels which were stuffed with RBC.Conclusions: We present this study to emphasize that sickle cell crisis is one of the cause of sudden unexplained death and highlight the importance of considering sickle cell disease as a cause of death in cases with no apparent cause.

Assessment of risk factors associated with pre-term labour in Tertiary care Hospitals, Lahore

2021 ◽  
Vol 15 (1) ◽  
pp. 13-17
Author(s):  
Tanzeela Zafar ◽  
Iram Manzoor ◽  
Fariha Farooq
Keyword(s):  
Risk Factors ◽  
Preterm Birth ◽  
Cesarean Section ◽  
Preterm Births ◽  
Intrauterine Death ◽  
Singleton Pregnancy ◽  
Factors Associated ◽  
History Of ◽  
Tract Infections ◽  
Inter Pregnancy Interval

Background: Pakistan has one of the highest rates of preterm births, nearly 16 for every 100 babies born. Around 4% of these premature babies, are at highest likelihood of death. The objective of this study was to assess association of multiple risk factors with preterm birth in Pakistani women. Patients and methods:  An analytical cross-sectional study was carried out in Obstetrics and Gynecology Department of Akhtar Saeed Trust Hospital and Farooq Hospital, West Wood Branch, Lahore from October 2018 to December 2019. Total 116 pregnant females who gave birth to preterm babies with gestational age between 20-37 weeks were included. Data about patients’ socio-demographic profile, previous obstetric history and current gestational profile was collected using closed ended structured questionnaire. Variables were presented in the form of frequency tables. Chi-square and Fisher exact test were applied to establish association of various risk factors and preterm presentation of patients’ in hospital. A p-value ≤ 0.05 was taken as significant. Results: Out of 116 participants, 49 (42.2%) were aged between 20-25 years, 47 (40.5%) were illiterate. Of the total sample 60 (51.7 %) participants were obese (BMI >30). Eighty-two (70.7%) patients were multigravida and 65 (56.1%) gave the history of previous cesarean section. Significant association was found between preterm birth and multi-parity (p=0.001), previous history of abortion (p=0.000), intrauterine death (p=0.001), infertility (p=0.04), cesarean-section (p=0.000), and inter-pregnancy interval of less than 24 months (p=0.007). Other significant factors associated with preterm labour were urinary tract infections (p=0.001), documented fever more than 101oF (p=0.000), anemia (p=0.000), singleton pregnancy (p=0.000) and cephalic fetal presentation (p=0.002), during current pregnancy. Conclusion: Multi-gravidity, history of abortion, intrauterine death, previous infertility, cesarean-section, inter-pregnancy interval of less than 24 months, UTI, genital tract infection, anemia, singleton pregnancy and cephalic fetal presentation during current pregnancy were observed to be significantly associated with preterm births.

scholarly journals CUT THROAT INJURY- A CRITICAL EMERGENCY: REVIEW OF 47 CASES IN A TERTIARY CARE CENTRE IN EASTERN INDIA

2020 ◽  
pp. 1-4
Author(s):  
Tithi Debnath ◽  
Jayanta Saha ◽  
Subhadeep Chowdhury
Keyword(s):  
Multidisciplinary Approach ◽  
Tertiary Care ◽  
Care Hospital ◽  
Tertiary Care Centre ◽  
Rural People ◽  
Common Cause ◽  
Mortality And Morbidity ◽  
Injury Patient ◽  
Zone Ii

Objective: To determine causes behind cut throat injury, analyse the demographics, evaluate treatment, complications, and outcome of cut throat injuries. Methodology: This prospective observational type of study was conducted at a tertiary care hospital during June 2018 to December 2019. A total of 47 cases included in this study. The demographics were recorded, and evaluation of the patient was done as per ATLS protocol. Necessary investigations were performed, and management was done by a team comprised of anaesthetist, otolaryngologist, CTVS surgeon and psychiatrist. After discharge of the patients, follow up was done for 6 months. Results: In our study the M: F is 3.27:1 and 36-50 years age group were mostly affected. Most common cause of injury was suicidal (61.70%). Majority patient had zone II injury (76.6%). 68.09% patients discharged within 8-14 days. Alteration of voice was most common complications (14.9%).61.70% patients are living completely normal life without any morbidity. Mortality rate after admission was 8.51%. Conclusion: Cut throat injury is common in middle aged male and rural people. Suicidal injuries are most common cause behind it. Early planned interventions, multidisciplinary approach, and regular follow up can reduce the mortality and morbidity of the cut throat injury patient.

scholarly journals A RETROSPECTIVE ANALYSIS OF HISTOPATHOLOGICAL SPECTRUM OF LESIONS IN NEPHRECTOMY SPECIMENS IN A TERTIARY CARE CENTRE

2020 ◽  
pp. 1-3
Author(s):  
K. Sitharamaiah ◽  
K. Anusha ◽  
G.Raja Sekhar ◽  
A. Bhagavan ◽  
G. Baleswari
Keyword(s):  
Tertiary Care ◽  
Chronic Pyelonephritis ◽  
Care Hospital ◽  
Geographical Differences ◽  
Tertiary Care Centre ◽  
Common Procedure ◽  
Neoplastic Lesion ◽  
Radiological Data ◽  
High Incidence ◽  
Neoplastic Lesions

Background: Kidneys can be involved in various pathological processes. Nephrectomy is a common procedure in urological practice. Indications for nephrectomy can display geographical differences in different countries around the world with different urological causes. The aim of the study was to analyse the various lesions in nephrectomy specimens in a tertiary care hospital in Kurnool, Andhra Pradesh, South India and also to know the frequency of lesions according to the age, gender and histology. Materials and Methods: It is a retrospective study, done over a period of 13 years from June 2007 to March 2020 which included 132 nephrectomy cases. Patient information such as age, gender, clinical diagnosis, radiological data such as USG and CT results, gross morphology and microscopic data were recorded from the available data. Results: Of 132 nephrectomy specimens, 55 (41.66%) were males and 77 (58.34%) were females. The mean age was 40.46 years. 99 (75%) nephrectomy specimens showed ‑ non‑neoplastic lesions and 33 (25%) showed neoplastic lesions. The most common non‑neoplastic lesions were chronic pyelonephritis in 62 (46.96%) patients, followed by tuberculous pyelonephritis in 20 (15.15%) patients. RCC (n = 27) was the most common neoplastic lesion. Conclusion: Chronic pyelonephritis remains the most common non-neoplastic cause of nephrectomy. RCC is the most common neoplastic cause of nephrectomy. Tuberculosis has a high incidence in developing countries. Awareness of renal TB is required for the physicians, to suspect this disease in patients with unexplained urinary tract abnormalities, particularly in those with any immunosuppression and those coming from TB-endemic areas.

scholarly journals Study of antibiotic prescription pattern in PICU of a tertiary care hospital

2018 ◽  
Vol 7 (12) ◽  
pp. 2319
Author(s):  
Vivek Virbhan Bamel ◽  
Savita Ramesh Shahani
Keyword(s):  
Respiratory Tract ◽  
Antibiotic Prescription ◽  
Tertiary Care ◽  
Care Hospital ◽  
National Guidelines ◽  
Mortality And Morbidity ◽  
Institutional Ethics ◽  
Causes Of Mortality ◽  
Tract Infections ◽  
Written Informed Consent

Background: Infectious disease is one of the importance causes of mortality and morbidity in India, therefore pattern of use of antibiotics requires separate study as they differ from adult, Therefore the aim of our study is to observe the antibiotic prescription in the tertiary care hospital.Methods: A prospective observational study was carried out in the children admitted in PICU. The study was started after obtaining the approval from Institutional Ethics Committee. Written informed consent was obtained from a parent or legal guardian of participants.Results: There were 50 patients were enrolled. The maximum antibiotics were prescribed from cephalosporin class (42; 40.38%) which included ceftriaxone, cefixime, cefotaxim, cefpodoxime. The majority of cephalosporins were prescribed in miscellaneous cases followed by respiratory tract infections, gastrointestinal tract, Central nervous tract infections and nil in CVS cases, secondly higher number of antibiotics prescribed was metronidazole and from Aminopenicillin class which includes amoxiclav and ampicillin and another beta lactamase which includes ureidopenicilin and carbepenem. The majority of aminopenicillin were prescribed in miscellaneous group infections followed by respiratory tract infections.Conclusions: From this study, it can conclude that commonly antibiotic were from 3rd generation cephalosporins followed by metronidazole and other β lactamase inhibitor and all of the antibiotics were prescribed as per the national guidelines.

scholarly journals Adverse drug reaction profile at psychiatry outpatient department of a tertiary care centre

2017 ◽  
Vol 6 (10) ◽  
pp. 2428
Author(s):  
Ujwala P. Gawali ◽  
Harshad V. Kesari ◽  
Komal S. Gawand
Keyword(s):  
Tertiary Care ◽  
Outpatient Department ◽  
Uppsala Monitoring Centre ◽  
Care Hospital ◽  
Causality Analysis ◽  
Care Centre ◽  
Tertiary Care Centre ◽  
Monitoring Centre ◽  
History Of ◽  
Reaction Profile

Background: Monitoring adverse drug reactions (ADRs) helps in alerting physicians and developing strategies to prevent and minimize the risk of developing ADRs. Data regarding pattern of ADRs due to psychotropic medications is scanty. Hence, the study was planned to assess ADRs among psychiatry outpatients of a tertiary care hospital in Maharashtra.Methods: A prospective, observational study was conducted in psychiatry outpatient department of a tertiary care centre for 3 months. Cases were enrolled by active and passive surveillance after obtaining informed consent. Demographic details, adverse event details, history of medications were recorded. Pattern of ADRs was studied according to demographic parameters, drug class, organ system affected, causality (WHO - Uppsala Monitoring Centre Scale) and severity (modified Hartwig and Siegel Scale).Results: Out of total 1200 patients screened, 77 qualified the inclusion and exclusion criteria and 92 ADRs were reported; overall incidence rate of 6.41%. Maximum ADRs were reported in the age group of 31- 40 years. 63.63% subjects received more than 2 psychotropic drugs. Among 24 types of ADRs observed, tremor (13.04%) was the commonest, closely followed by somnolence. Antipsychotics (45.65%) were most frequently incriminated and central nervous system (46.73%) the most often affected. Trifluoperazine (11.96%) was the commonest drug, followed by olanzapine and haloperidol (10.53% each). Causality analysis yielded 66 ADRs as “probable” and on severity analysis 80.43% were mild.Conclusions: The study provides an insight into pattern of ADRs in psychiatry outpatients. It is prudent to communicate this to treating physicians as well as counsel patients (and caregivers). Initiatives and concerted efforts involving all stakeholders in healthcare can go a long way in decreasing drug-related morbidity and health costs.

Sign in / Sign up

Export Citation Format

Share Document