scholarly journals Maternal and foetal outcome in preterm births in a rural tertiary care centre: a retrospective study

2021 ◽  
Vol 11 (1) ◽  
pp. 50
Author(s):  
Deeksha Rao M. ◽  
Vasantha Kumar S.
Keyword(s):  
Retrospective Study ◽  
Preterm Birth ◽  
Tertiary Care ◽  
Preterm Births ◽  
Morbidity And Mortality ◽  
Care Hospital ◽  
Tertiary Care Centre ◽  
Mortality And Morbidity ◽  
Medical Disorders ◽  
Nicu Admission

Background: Preterm birth (PTB) is one of the main causes of perinatal mortality and morbidity. It can also result in long term health consequences for both mother and the newborn. The objective was to assess maternal and fetal morbidity and mortality in PTBs.Methods: A retrospective study was done in the department of obstetrics and gynecology in a tertiary care hospital during January 2020 and June 2020. Ninety-three women with records of preterm births were analyzed for maternal and fetal outcomes. coGuide statistical software was used for data analysis.Results: 48.39% of the women were between 20 to 24 years of age. The majority (50.54%) were primigravida. The main causes for PTB among the study participants were medical disorders (39.78%), PPROM (29.03%), spontaneous labor without any underlying cause (18.28%). 51.61% had a vaginal delivery, 88.17% had a live birth. The majority of 52 (55.91%) neonates had birth weights between 1.51 to 2.5 kg. Fifty-nine neonates (63.44%) needed NICU admission. The reason for NICU admission in majority 25 (26.88%) was respiratory distress.Conclusions: Timely, early diagnosis and treatment of medical disorders among antenatal women can aid in reducing the occurrence of preterm births and their associated morbidity and mortality. Medical disorders and premature preterm rupture of membrane remain the main causes of preterm birth. 

scholarly journals A study of etiology and outcome of preterm birth at a tertiary care centre

2017 ◽  
Vol 6 (10) ◽  
pp. 4488
Author(s):  
Shaveta Garg ◽  
Tajinder Kaur ◽  
Ajayveer Singh Saran ◽  
Monu Yadav
Keyword(s):  
Preterm Birth ◽  
Tertiary Care ◽  
Preterm Births ◽  
Active Phase ◽  
Care Hospital ◽  
Tertiary Care Centre ◽  
Mortality And Morbidity ◽  
High Incidence ◽  
History Of ◽  
Tract Infections

Background: Preterm births are still the leading cause of perinatal mortality and morbidity. It is a major challenge in the obstetrical health care.Methods: This study was conducted over a period of eight months from September 2016 till April 2017 at a tertiary care hospital. All patients who delivered a live baby before 37 weeks of gestation were included in the study.Results: Present study was conducted on 100 eligible women out of which 7 delivered before 30 weeks but majority of them (55%) delivered after 34 weeks of gestation. In our study, most of the patients (66%) presented in active phase of labor which resulted in preterm birth of baby. The most common risk factor of preterm labor was genitourinary tract infections (34%) followed by Preterm Premature rupture of membranes (22%). Past obstetric history of preterm delivery and abortions also had a significant impact on the present pregnancy outcome.Conclusions: Preterm labour and birth still have a high incidence causing significant neonatal mortality and morbidity as well as economic burden on family and hospital. The causes of preterm birth are multifactorial and modifiable. This incidence can be reduced by early identification of established risk factors, as revisited and reemphasized in our study, with the help of universal and proper antenatal care.

scholarly journals Outcome of moderate preterm and term babies at tertiary care centre

2018 ◽  
Vol 5 (6) ◽  
pp. 2222
Author(s):  
Shaitan Singh Balai ◽  
Durgavati Katara ◽  
Vivek Arora
Keyword(s):  
Gestational Age ◽  
Tertiary Care ◽  
Preterm Births ◽  
Preterm Neonates ◽  
Care Hospital ◽  
Tertiary Care Centre ◽  
Major Morbidity ◽  
Mortality And Morbidity ◽  
Maternal Risk ◽  
Maternal Hypertension

Background: To study the maternal risk factors, morbidity, mortality of moderate preterm in comparison to term neonates.Methods: This Cohort study involved two hundred fifty consecutively born moderate preterm and equal number of term newborns delivered in a tertiary care hospital. They were followed till discharge for morbidities and mortality. Detailed maternal and neonatal factors were studied and compared between the two groups.Results: Moderate preterm babies constituted 55% of all live preterm births during the study period. The odds of babies developing major morbidity was significantly more in those whose mothers had hypertension and infections (OR 2.69 95% CI: 1.55, 4.68 and 2.08, 95% CI: 1.6, 2.71 respectively). In the study group, 42.4% and 20.8% babies suffered major and minor morbidity compared to 8.4% and 6.8% of term controls respectively. moderate preterm neonates had significantly higher odds of developing morbidity like respiratory distress (12.4% vs. 5.6%, OR 2.21, 95%CI 1.21,4.11), need for non-invasive(17.3% vs. 5.7%, OR 3.05 95% CI 1.69, 5.47) and invasive ventilation (14.6% vs. 1.7%, OR 8.62, 95% CI 3.09, 24.04), sepsis (20.8% vs. 5.2%, OR 5.20, 95% CI 2.71, 9.99), seizures (22.8% vs. 4.8%, OR 4.75 95%CI 2.61, 8.63), shock (17.6% vs. 4.4%, OR 4.00 95% CI 2.12,7.56), and jaundice (26% vs. 6%, OR 4.33 95%CI 2.54, 7.39). By logistic regression, the odds of developing major morbidity decreased with increasing gestational age (aOR 0.28 95% CI 0.18, 0.45; p<0.001) and increased with hypertensive disease of pregnancy (aOR 2.16 95% CI 1.09, 4.260; p00.026).Conclusions: Moderate preterm neonates have significantly more mortality and morbidity compared to term controls. Maternal hypertension and lower gestational age are the strongest predictors of morbidity.

scholarly journals Rising trend in cesarean sections: a retrospective study at tertiary care hospital in Jammu

2021 ◽  
Vol 10 (5) ◽  
pp. 1958
Author(s):  
Shazia Zargar ◽  
Nikita Gandotra
Keyword(s):  
Retrospective Study ◽  
Health Care Providers ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Fetal Distress ◽  
Care Hospital ◽  
Care Providers ◽  
Cesarean Sections ◽  
Mortality And Morbidity ◽  
Maternal Mortality And Morbidity

Background: The uncontrolled wave of cesarean rates has increased globally which has resulted in a significant amount of maternal mortality and morbidity. The present study aims to evaluate the trend in cesarean section rates in Jammu, India. Methods: The present retrospective study was carried out at the department of Obstetrics and Gynecology, SMGS Hospital, Jammu, India. We collected data based on total number of deliveries and cesarean sections performed at the hospital during (March2015-Feb2020) along with indications for CS.Results: The percentage of cesarean sections has increased drastically from 39.4% during (2015-16) to 49.9% in (2019-20). The study shows that the most common indication for CS is post CS followed by NPOL, Fetal distress, breech, APH, CPD, PIH and others.Conclusions: There is a growing concern among public and health care providers regarding the escalating and uncontrolled trend of cesarean sections which needs to be curtailed within optimal limits recommended by WHO. 

scholarly journals Whipple's pancreaticoduodenectomy: perioperative outcomes in a tertiary care hospital in Dhaka, Bangladesh

2021 ◽  
Vol 9 (3) ◽  
pp. 696
Author(s):  
A. B. M. Bayezid Hossain ◽  
Sadia Afroz ◽  
M. Tasnimul Khair Shovon ◽  
Nabila Anjuman ◽  
Mitul Chackraborty
Keyword(s):  
Mortality Rate ◽  
Tertiary Care ◽  
Morbidity And Mortality ◽  
Perioperative Outcomes ◽  
Care Hospital ◽  
Mortality And Morbidity ◽  
Medical College ◽  
Presenting Symptoms ◽  
Critical Care Management ◽  
Considerable Morbidity

Background: Pancreaticoduodenectomy is one of the most complex surgery with significant mortality and morbidity. Though the mortality rate has steadily improved, morbidity continues to be high. The aim of this study was to demonstrate the perioperative outcome following this procedure at our hospital.Methods: This retrospective study was conducted in the department of Surgery, Sir Salimullah medical college and Mitford hospital from July 2018 to December 2019. A total of 29 patients who undergone pancreaticoduodenectomy were included in the study. Preoperative, intra-operative and post-operative data were analyzed with emphasis on the morbidity and mortality rates. None of the operated patients received any types of neoadjuvant therapy.Results: Out of 29 patients who underwent PD, 18 (62.1%) were male and 11 (37.9%) were female with a median age of 53.7 years. The most common (34.5%) age group of the patients were 51-60 years. Jaundice was the commonest (89.7%) presenting symptoms followed by anorexia (75.9%) and abdominal pain (48.3%). Overall complications occurred in 37.9% patients, including wound infections (31.0%) and post-operative pancreatic fistula (6.9%). The post-operative mortality rate was 6.9%.Conclusions: PD still causes considerable morbidity and mortality. With careful patient selection, adequate preoperative preparation, surgical technique, excellent critical care management PD can be performed safely. At our center we have a reasonable volume and our data are comparable to literature data. 

scholarly journals Does advanced maternal age influence obstetric outcome: a study in a tertiary care centre

2019 ◽  
Vol 8 (4) ◽  
pp. 1313
Author(s):  
Jose C. V. ◽  
Lissiamma George ◽  
Sunitha Sukumaran
Keyword(s):  
High Risk ◽  
Gestational Diabetes ◽  
Maternal Age ◽  
Tertiary Care ◽  
Advanced Maternal Age ◽  
Chronic Hypertension ◽  
Care Hospital ◽  
Tertiary Care Centre ◽  
Younger Women ◽  
Medical Disorders

Background: Advanced maternal age defined as age 35 years and older at estimated date of delivery has become increasingly common in last two to three decades. The International Federation of Gynaecology and Obstetrics in 1958 recommended that all women going through their first pregnancy over the age of 35 years should be considered high risk for pregnancy and included in this category 1.Methods: A one-year prospective observational study conducted in a tertiary care hospital after institutional ethical clearance. All 165 women above 35yrs who delivered during this period were taken as Cohort 1. Same number of women aged between 20 and 34 years were randomly selected as comparison group (Cohort 2). Both the groups were compared in terms of preexisting medical disorders, obstetrical morbidities, antenatal complications, intrapartum complications.Results: Older and younger women had similar antenatal booking, occupational and socioeconomic status. The main reason for pregnancy at advanced age group was late marriage. The risk of chronic hypertension, gestational diabetes mellitus, pre-existing medical disorders were higher in advanced maternal age.Conclusions: Increasing maternal age is associated with elevated risks for pregnancy complications. They are at high risk for gestational diabetes, cesarean section and to have low birth weight babies. Since these women are at higher risk of complications, they should be advised to adhere to frequent antenatal visits and close supervision.

scholarly journals Maternal and perinatal outcome of oligohydramnios in term pregnancy in rural tertiary care centre

2019 ◽  
Vol 8 (2) ◽  
pp. 389
Author(s):  
Swati Kagne ◽  
Sambhaji Chate
Keyword(s):  
Birth Weight ◽  
Amniotic Fluid ◽  
Perinatal Outcome ◽  
Tertiary Care ◽  
Care Hospital ◽  
Perinatal Complications ◽  
Term Pregnancy ◽  
Tertiary Care Centre ◽  
Study Population ◽  
Nicu Admission

Background: Disorders of amniotic volume is one of the commonest obstetric problem. Amniotic fluid acts as cushion to the foetus allowing musculoskeletal development and also helps in the differentiation of lungs and gastrointestinal tract. Decreased amniotic fluid, known as oligohydramnios, is known to be associated with adverse perinatal outcome. The objective is to study the maternal and perinatal complications of oligohydramnios in term pregnancy.Methods: The present study was carried out in the Department of Obstetrics at rural tertiary care hospital in Maharashtra from February 2018 through October 2018. women with Oligohyamnios were studied for obstetrical and neonatal complications.Results: The incidence of oligohyamnios was 7.6% in present study. The mean age of the study population was 22.6±3.6 years. Induction of labour was required in 44 (61.11%) patients out of which 23 patients underwent emergency LSCS. Low birth weight (birth weight<2.5kg) was found in 14 (19.44%) babies with 11 babies having intrauterine growth restriction. 5-minute APGAR (appearance, pulse, grimace, activity, respiration) score was <7 in 13.88% babies. 16 babied needed NICU admission out of which 1 neonate died.Conclusions: Detection of oligohydramnios increases obstetrical interventions in term pregnancy.

CLINICO-MICROBIOLOGICAL PROFILE AND FETO-MATERNAL OUTCOME IN PRETERM PREMATURE RUPTURE OF MEMBRANES: A 1YEAR PROSPECTIVE, TERTIARY CARE SINGLE-CENTRE STUDY.

2020 ◽  
pp. 5-7
Author(s):  
Shridevi Metgud ◽  
Ramita Malla ◽  
Sharada Metgud
Keyword(s):  
Tertiary Care ◽  
Preterm Births ◽  
Obstetric Outcome ◽  
Premature Rupture Of Membranes ◽  
Premature Rupture ◽  
Tertiary Care Centre ◽  
Vaginal Infections ◽  
Preterm Premature Rupture ◽  
Single Centre Study ◽  
Nicu Admission

Background- The global burden of premature babies is mostly contributed by preterm births. Preterm premature rupture of membranes (PPROM) account for nearly 40% of all preterm deliveries. Objective-The study was done to evaluate the clinic-bacteriological prole and the obstetric outcome in pregnancies complicated by preterm premature rupture of membranes. Material and methods-This was a prospective cohort study of cases of PPROM admitted in the teaching hospital which is a major referral tertiary care centre. A total of 64 women were enrolled. We studied the patient demographics, bacterial prole and obstetric outcome in these women. Results-Most of the cases of PPROM were seen in low risk primigravidae. Infections were the commonest cause for PPROM. Enterococcus Faecalis was the most commonly isolated organism. The mean latent period was 3-7 days. Most women delivered vaginally. Respiratory distress and low birth weight with Apgar <6 were the common indications for NICU admission. Co-relation between TLC and hs-CRP levels was not statistically signicant across different groups. Conclusion- Effective screening for cervico-vaginal infections in pregnancy and appropriate antibiotic therapy will help reduce infection related feto-maternal morbidity and mortality. Lesser gestational ages are associated with poorer outcome.

NASOPHARYNGEAL CARCINOMA: A CHANGING TREND IN EPIDEMIOLOGY ,INCIDENCE RATE AND TREATMENT PROSPECTS IN TERTIARY CARE HOSPITAL

2021 ◽  
pp. 37-39
Author(s):  
Nabajyoti Saikia ◽  
Priyanka Agarwal ◽  
Shilpi Gupta
Keyword(s):  
Retrospective Study ◽  
Nasopharyngeal Carcinoma ◽  
Tertiary Care ◽  
Neck Surgery ◽  
Endoscopic Biopsy ◽  
High Rate ◽  
Care Hospital ◽  
Care Centre ◽  
Tertiary Care Centre ◽  
Ajcc Staging

Introduction: Nasopharyngeal carcinoma is a rare disease all over the world. It has often been less evaluated, misdiagnosed, partially treated and above all has poor prognosis with high rate of recurrence. This study is a retrospective study which shows an increase in the incidence of Nasopharyngeal carcinoma in the upper- Assam region of India. There has been an upsurge in the number of cases reporting to Department of Otolaryngology and Head and Neck Surgery in Tertiary Care Centre, Assam, India. Methods: This is a retrospective study of eight cases reporting in a tertiary care centre In a span of 6months (Jan 19'- Jun 19').Detailed history and clinical examination of each case was done. Diagnosis conrmed with nasal endoscopic biopsy .Staging of all the cases were done with CT scan and MRI . A total of eight cases were included in study which reported in our department Results: in 6 months period.6 were male (75%) and 2 females (25%).AJCC staging of study group was Stage I- 1 patient ,Stage II-2patient,Stage III-2patient and StageIV-3patient. Increasing rate Conclusion: of Nasopharyngeal carcinoma in upper Assam region is alarming and cases should be properly evaluated and investigated as the available treatment is rewarding

A Retrospective Study of Pemphigus in a Tertiary Care Centre in South India

2021 ◽  
Vol 8 (31) ◽  
pp. 2913-2918
Author(s):  
Simon Sheena Ann
Keyword(s):  
Histopathological Examination ◽  
Demographic Data ◽  
Tertiary Care ◽  
Immunosuppressive Treatment ◽  
Care Hospital ◽  
Age Group ◽  
Tertiary Care Centre ◽  
Medical Disorders ◽  
Autoimmune Bullous Diseases ◽  
Mucosal Involvement

BACKGROUND Pemphigus is a group of rare, life-threatening autoimmune bullous diseases of the skin and mucosa which result in intraepidermal blistering. Associated autoimmune conditions and the extensive mucocutaneous detachment impair the quality of life. Immunosuppressive treatment adds to the morbidity in patients. We wanted to assess the clinical presentation of pemphigus among the study subjects along with the outcome of pemphigus patients with the extent of the disease and results of pus culture. METHODS Retrospective analysis of case records of patients with pemphigus in a tertiary care hospital during a period of 3 years was done in 2015. Demographic data, clinical findings, underlying medical disorders, details of deaths, investigation reports and treatment details were recorded. RESULTS Common age group affected was 51-60 years (31.5 %) among a total of 54 pemphigus patients. There were 26 males and 28 (51. 9 %) females and in majority of the patients (44.4 %) duration was less than 6 months. Out of 47 patients, oral mucosal involvement was grade 1 in 20 (37 %) cases, grade 2 in 12 (22.2 %) and in 15 (27.8 %) patients it was grade 3.Histopathological examination showed suprabasal cleft in 82.1 %, subcorneal blister in 5.7 %, acantholytic cells in 48.6 % and row of tombstone appearance in 9.4 %. Out of 36 patients, DIF test reported intercellular IgG in 65 % and C3 in 50 % .Diabetes was found in 14 (25.9 %), candidiasis in 12 (22.2 %), thyroid disease in 6 (11.1 %) and hypertension in 3 patients. Three patients died. Among 10 patients with more than 30 % body surface area involvement, 1 (10 %) patient died. Two (13 %) deaths occurred among 15 patients in whom pus C&S was positive. CONCLUSIONS Pemphigus patients were of slightly higher (51 - 70 years) age group and the 3 patients died were females. Autoimmune disorders like diabetes and thyroid disorders were found among many patients and their family members. Infection could be an important cause of death, but no statistically significant association was found in the present study. KEYWORDS Pemphigus, Steroids, Comorbidity, Deaths

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