scholarly journals Clinical study of central serous chorioretinopathy presenting in a tertiary care centre

Author(s):  
Ramamani Dalai ◽  
Rajashree Rout ◽  
Manjula Pradhan ◽  
Prasanta Kumar Nanda

Background: Central Serous chorioretinopathy (CSCR) is one of the common causes of visual handicap affecting young people of highly intellectual professionals at the peak of their career which can lead to irrecoverable loss of vision.Methods: The present prospective observational population-based study was conducted in the Department of Ophthalmology, S.C.B. Medical College, Cuttack, Odisha from October 2013 to September 2015. The total number of patients attended the Outpatient Department (OPD) during the study period were 1,83,199. Amongst which 123 patients diagnosed to have CSCR were selected for the present study.Results: Incidence of CSCR during in this study period was 0.06%. The age group most commonly affected was 31 to 40 years. Males were affected 7 times more commonly than females. Increased incidence was noticed in bank employees (21.1 %) and IT professionals (17.8%).Conclusions: There was increased incidence of the disease in people under stressful life condition.

2016 ◽  
Vol 54 (201) ◽  
pp. 24-28 ◽  
Author(s):  
Sita Ghimire

Introduction: Eclampsia is a preventable and treatable cause of maternal morbidity and mortality with poor feto-maternal outcome in developing countries. Despite development in the level of health education expertise in human resources and institutional obstetric care in our country, the delay in early recognition of the problem, transportation to proper health facility and getting proper expert care are major hurdles to reduce complications. Therefore we decided to study feto-maternal outcomes in our setting.Methods: A retrospective cross-sectional hospital based study carried out in Nobel Medical College, Biratnagar, from 17th June 2014 to 16th June 2015. Details and data obtained from Medical Record Section were analysed. All patients with eclampsia were included and fetomaternal outcomes measured in terms of complications. Simple descriptive statistical method was applied for analysis.Results: Among 8,066 deliveries, 112 had eclampsia with incidence of 13.8/1000 deliveries. Majority (41%) were of <19 years of age. Above 90% were unbooked. Aoubt 63.4% were primiparas and 83% had antepartum eclampsia. Eclamptic fits were more common (41.6%) in 37-40 weeks period of gestation. Fits to delivery interval was more than six hours in 89.1% women and 69.3% women underwent caesarean delivery. About 18.9% women developed eclampsia related complications. Common causes of maternal deaths (5.36%) were pulmonary edema, aspiration pneumonia, cerebrovascular accidents and HELLP syndrome. Perinatal death was nine percent.Conclusions: Although the obstetric care facilities are improving with time, the feto-maternal outcomes are still poor in our country. Therefore early recognition and proper management are vital to tackle this challenge. Keywords: eclampsia; fetomaternal outcomes; retrospective analysis. | PubMed


Author(s):  
Raghu M. T. ◽  
Ashwini S. ◽  
Yogendra M. ◽  
Virupakshappa H. E. ◽  
Gangaraju Harish ◽  
...  

<p class="abstract"><strong>Background:</strong> Cutaneous tuberculosis (TB) is frequently found worldwide, especially in tropical countries. The number of extrapulmonary TB reaches up to 14%, and 1% to 2% are cutaneous TB. Diagnosis of cutaneous tuberculosis (CTB) is complicated and requires a full work-up. Clinical manifestation of cutaneous TB is varied and causes difficulties to diagnose. Scrofuloderma and plaque type of lupus vulgaris (LV) are common forms of cutaneous TB.</p><p class="abstract"><strong>Methods:</strong> A retrospective study was conducted on patients attending Department of Dermatology, Venereology and Leprosy, at Basaveshwara Medical College and Hospital, Chitradurga over a period of 2 years. A total of 15 cases of cutaneous tuberculosis were diagnosed.</p><p class="abstract"><strong>Results:</strong> A total of 15 cases out of which included predominantly males, with age group being affected commonly are 20-40 decades, histopathology showing tuberculoid granuloma in 11 cases, and common clinical variant being lupus vulgaris seen in 66.6% of the cases and. Second common being scrufuloderma seen in 26.6% of the cases and least common is TB verrucosa cutis (TBVC) seen in 6.6% of the cases.</p><p class="abstract"><strong>Conclusions:</strong> The study showed that the common clinical type of cutaneous tuberculosis during the study period was lupus vulgaris, scrofuloderma and less common being TBVC.</p>


Author(s):  
Pratibha Garg ◽  
Urmila Tripathi

Background: Pregnancy poses unique consideration for critical care and it is imperative that obstetrician and other members of health care team have a working knowledge of these factors because these are women are usually young and in good health, their prognosis should be better than that of many other patients admitted to an intensive care.Methods: The present study was conducted in the Department of Obstetrics and Gynaecology, Gaja Raja Medical College and associate Kamla raja Hospital, Gwalior in the ICU from Oct. 14 to Oct. 15.Results: 678 obstetric women were admitted into the ICU of Kamla Raja Hospital, over a period of 1 year study period. Maximum number of patients belong to age group 21-25 years (54.8%), 398 (58.7%) patients were uneducated, 343 (50.59%) came directly to Kamla Raja Hospital. 362 (53.39%) belongs to urban area. The mean length of stay in ICU was 3 days. Maximum number of patients were postpartum 580 (85.55%). According to mode of delivery maximum number of patients 348 (51.33%) underwent LSCS. Most common obstetric indication for admission in ICU was hypertensive disorder of pregnancy 472 (69.61%). Most common medical indication was severe anaemia 128 (18.87%). Various type intervention like pulse oxymetry, O2 inhalation, BT, nebulisation and ventilation were done in ICU according to patients need. 43 maternal death happened during the study period with most common cause was cardiorespiratory arrest 9 (1.32%) and pulmonary edema 8 (1.17%).Conclusions: Establishment of a dedicated obstetric ICU at tertiary care centre with knowledge familiarity, experience and expertise of an obstetrician and a special team would be best place to monitor and treat the critically ill obstetric patients which will reduce the maternal morbidity and mortality.


Author(s):  
Smruti Milan Tripathy ◽  
Poonji Gupta ◽  
Akshay Jain ◽  
Probal Chatterji

<p class="abstract"><strong>Background:</strong> Lesions of the oral cavity are very common among the general population and account for a significant number of patients in the outpatient department of otorhinolaryngology. The lesions of oral cavity can cause varied symptoms like pain, dysphagia, and difficulty in speaking. The lesions can range from simple benign conditions to life threatening malignancies.</p><p class="abstract"><strong>Methods:</strong> This study was conducted in the department of otorhinolaryngology, Teerthanker Mahaveer Medical College and Research Centre from January 2019 till December 2019. All the 256 patients who presented to the outpatient department with lesions in the oral cavity during the given time period were included in the study after getting informed and written consent.  </p><p class="abstract"><strong>Results:</strong> Aphthous ulcers were the most common lesion (18.7%) found in this study. Buccal mucosa (50%) and anterior 2/3<sup>rd</sup> of tongue (34.3%) were the most common sites involved. Total of 204/256 (79.6%) patient had some form of addiction which included both smoked and smokeless form of tobacco as the most common type of addiction. Among the tobacco smokers, 24/80 (30%) had pre malignant and malignant lesions while among tobacco chewers 37/76 (48.6%) had pre malignant and malignant lesions.</p><p class="abstract"><strong>Conclusions:</strong> Lesions of the oral cavity are common among Indian population due to high prevalence of tobacco addiction. A thorough history taking and examination can detect premalignant and malignant lesions at an early stage, so that timely treatment can reduce the mortality rates in such patients.</p>


2020 ◽  
Vol 5 (2) ◽  
pp. 1050-1054
Author(s):  
Ram Hari Ghimire ◽  
Ashima Ghimire ◽  
Rupesh Kumar Shreewastav ◽  
Sushil Yadav ◽  
Bidesh Bidesh Bista

Introduction: Hemoptysis is a common but distressing and alarming symptom in a patient. Data related to detail clinical profile and follow up study of hemoptysis are lacking. Objective: This study was carried out to see the clinical profile of patients with hemoptysis and to study the recurrences in tertiary care centre of province 1 within the study period. Methodology: This was a prospective observational study conducted at the department of Pulmonary, Critical Care and Sleep Medicine of Nobel Medical College and Teaching Hospital, Biratnagar, Nepal. The study was carried out between 30th January 2017 to 1st February 2020. For follow up of recurrences of hemoptysis, the patients were asked for regular chest clinic follow up and regular telephone calls made to the patients, in case, patients could not attend the chest clinic for any reason. Results: A total of 150 patients were enrolled over the last 3 years. Among them 75% were male. The maximum number of patients (27%) were between 31-40 years of age group. Old sequelae of pulmonary tuberculosis (PTB) (32%) and bronchiectasis (28%) were the commonest cause of hemoptysis. Lung cancer (10%) and active PTB (10%) were other causes of hemoptysis. CT scan of the chest provided the highest (84%) diagnostic yield. Most of the cases were having mild hemoptysis (50%). 17% of the patients in our study had recurrences of hemoptysis. Conclusion: Old PTB sequelae with bronchiectasis (fibrobronchiectasis) were the commonest cause of hemoptysis. Conservative management worked most effectively in controlling hemoptysis, if used properly.


2019 ◽  
Vol 6 (2) ◽  
pp. 295
Author(s):  
Jaishree Ambhore ◽  
Minhajuddin Ahmed

Background: Rotavirus and Adenovirus is considered to be an important cause of diarrhoea in under five children and the data is very scarce due to decrease testing. This study was done to estimate the incidence, clinical profile and laboratory features among under five children with diarrhoea.Methods: A prospective interventional study was conducted in Chirayu Medical College, Bhopal on children aged between 6 months - 5 years hospitalized with acute non-bloody diarrhea with 30 children in each group.Results: Total 328 children were included in the study out of which 216 were males and 112 were females with a male:female ratio 1.9:1. 92(28%) patients were positive for rotavirus out of which 64(19.5%) were males and 28(8.5%) were females in present study.Conclusions: Rotavirus infection is one of the common etiological agents responsible for diarrohea. Rotavirus infection results in disease burden with morbidity and mortality in children and vaccination is the only control measure to decrease the incidence and mortality in children.


Author(s):  
Shailendra Singh ◽  
Shantipriya Bhardwaj ◽  
Kuldeep Jareda ◽  
Amit Sharma ◽  
Keshari Singh Shekawat

Background: This study was undertaken to ascertain the total patients receiving a transfusion, indications for transfusion, various blood components used, the timing of transfusion, and the presence of any risk factors in the patients transfused. Methods: Transfusion request forms of 2998 patients admitted to the Department of Gynaecology and Obstetrics in the zanana Hospital, SMS Medical College and attached group of hospitals Jaipur from May 2020 to July 2020were retrospectively reviewed for the types and volume of blood component transfused. Indication for each blood component transfusion was noted. Patients who had MOH were further analyzed to estimate the ratio of components transfused. Results: We have experienced 898 obstetric patients who underwent blood component transfusion during the study period. Out of these, 440 (49%) and 458 (51%) were primigravida and multigravida respectively. The mean age of patients who received transfusion was 27 years. The maximum number of patients was in the age group of 21–32 years Conclusion: Anemia during pregnancy is a significant cause of maternal mortality and morbidity. The decision for transfusion was done in this study when the Hb<7 gm%, and there were <4 weeks for delivery or in labor Keywords: Hb, Anemia, Pregnancy.


2020 ◽  
Vol 35 (4) ◽  
pp. 235-241
Author(s):  
Asfandyar Asghar ◽  
Amna Rizwan ◽  
Naila Obaid ◽  
Ume Sughra ◽  
Badar Ud Din Ather Naeem ◽  
...  

PURPOSE: To determine the safety of multiple doses preparation of bevacizumab from single vial in minor theatre in reducing the frequency of endophthalmitis. STUDY DESIGN: Retrospective exposure study PLACE AND DURATION OF STUDY: Department of Ophthalmology, Fauji Foundation Hospital (FFH), Rawalpindi from June 2016 to March 2018. MATERIAL AND METHODS: 1690 eyes belonging to 1001 patients was included using computer logs of patients receiving intravitreal bevacizumab (IVB). In FFH, we allocate three consecutive days every month in order to administer IVB. Approximately 50 patients were typically given IVB over three-days period.1-2 ml (depending upon the number of patients) of bevacizumab was withdrawn in a 3 cc syringe.1 cc insulin syringe with 29 G needle was taken and, 0.05 ml (1.25 mg) bevacizumab was injected from behind using the 3 cc syringe, resulting in preparation of 10-20 injections of IVB. The bevacizumab vial was then stored at 4 degrees Celsius. RESULTS: Total 1690 eyes belonging to 1001 patients were analyzed. The occurrence of endophthalmitis was 2/1690 (0.12%) corresponding to a 95% CI of 0.03%-0.43%, which does not represent an increase in cases as compared to endophthalmitis resulting from using a compounding pharmacy. CONCLUSION: Whereas, a priori, it seems reasonable to assume that aliquot preparation and storage of bevacizumab for intravitreal use particularly by a compounding pharmacy is safer. We, however, show that our preparation of IVB from single vial technique using proper sterilization is equally safe. Due to the reduced cost of our technique, we recommend it, particularly in the developing world.


2019 ◽  
Vol 46 (3) ◽  
pp. 90-93
Author(s):  
Purabi Rani Debnath ◽  
Mohammuddunnobi

Diabetic retinopathy (DR) is one of the most common causes of blindness in developed countries. Early detection of diabetic retinopathy (DR) is crucial for preventing irreversible blindness. To measure the association of diabetic retinopathy with dabetic foot a cross-sectional study was carried out at Department of Ophthalmology and Surgery, BIRDEM General Hospital, Dhaka from January 2017 to September 2017. Patients were included, who were known diabetic. New cases of type-2 diabetes were also included because they might have complications at the time of diagnosis because of the nature of disease. Mean duration of diabetes was significantly higher in DFU with DR group. BUN and diabetes retinopathy were statistically significant (p<0.05) between two groups. Mean HbA1c, pre-prandial glucose, C-peptide, cholesterol, triglyceride, HDL, LDL, hematocrit, creatinine, ABI, TBI and DM foot ulcer were not statistically significant (p>0.05) between two groups. Most patients (33.3%) had a grade I ulcer in DF with DR group and 33.3% in DF without DR group. Medication taking was significantly high patients who were DF without DR. Combined agents was 11(36.7%) and 11(36.7%) in DF with DR and DF without DR group respectively. Insulin was taken 16(53.3%) in DF with DR group and 19(63.3%) in DF without DR group. Maximum patients had a grade I ulcer in diabetes foot ulcer. Medication taking was significantly high patients who were diabetes foot ulcer than without diabetes foot ulcer. Mean insulin, BUN and diabetes retinopathy was found significantly higher in diabetes with diabetes foot ulcer. Mean insulin BUN and diabetic retinopathy was was significantly higher in diabetes with diabetes foot ulcer. Bangladesh Med J. 2017 Sep; 46 (3): 90-93


Author(s):  
Binu Areekal ◽  
Sudhiraj Thiruthara Sukumaran ◽  
Andrews Mekkattukunnel Andrews ◽  
Sreejith Parayil Nanu ◽  
Indira Madhavan ◽  
...  

Introduction: Coronavirus Disease-19 (COVID-19) pandemic is posing a challenge not only with sheer number of people infected but also with the large number of patients with persistent symptoms of COVID-19 infection. A proper understanding of the magnitude and associated factors of persistent COVID-19 symptoms will go a long way in planning treatment and control strategies. Aim: To determine the proportion of patients who have persistent symptoms post acute COVID-19 infection and to determine the factors associated with it, among those who have been discharged from Government Medical College, Thrissur, Kerala, India. Materials and Methods: The current cross-sectional study was conducted among 335 patients who were admitted and discharged with COVID-19 infection in Government Medical College, Thrissur, Kerala, a tertiary care institution in southern India between December 2020 and February 2021. They were contacted through a telephonic interview 28 days from symptom onset through a semi-structured interview schedule. The questions included basic demographic details, symptomatology at admission, persistent symptoms at 28 days after onset and other clinical details including comorbidities. For defining post COVID-19 symptom persistence National Institute for Health and Care (NICE) guidelines were used. Association between persistent symptoms and selected factors was done by Chi-square test. Results: Out of the 335 patients, the persistence of symptoms of COVID-19 infection after 28 days of symptom onset was 221 (66%) (CI 60.7-79.8). Persistence of two or more COVID-19 symptoms after 28 days of onset was seen in 120 (35.8%). The most common persistent symptoms among the patients were fatigue in 109 (32.5%) of people followed by dyspnoea in 77 (23%), cough in 45 (13.4%) and myalgia in 37 (11%) patients. Highest persistence was seen in Category C patients where symptoms were persisting in 75%. Persistence was also higher in those with Diabetes Mellitus (DM), those who received oxygen support and those who were in Intensive Care Unit (ICU) or on ventilator and the association was statistically significant (p-value <0.05). Conclusion: The study shows that two-third of patients still continues to have persistent symptoms even after 28 days of symptom onset. Health systems should be prepared to face the consequences of morbidities caused by post COVID-19 syndrome.


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