scholarly journals Prevalence of oral mucosal lesions in a tertiary care centre: one-year prospective study

Author(s):  
Smruti Milan Tripathy ◽  
Poonji Gupta ◽  
Akshay Jain ◽  
Probal Chatterji

<p class="abstract"><strong>Background:</strong> Lesions of the oral cavity are very common among the general population and account for a significant number of patients in the outpatient department of otorhinolaryngology. The lesions of oral cavity can cause varied symptoms like pain, dysphagia, and difficulty in speaking. The lesions can range from simple benign conditions to life threatening malignancies.</p><p class="abstract"><strong>Methods:</strong> This study was conducted in the department of otorhinolaryngology, Teerthanker Mahaveer Medical College and Research Centre from January 2019 till December 2019. All the 256 patients who presented to the outpatient department with lesions in the oral cavity during the given time period were included in the study after getting informed and written consent.  </p><p class="abstract"><strong>Results:</strong> Aphthous ulcers were the most common lesion (18.7%) found in this study. Buccal mucosa (50%) and anterior 2/3<sup>rd</sup> of tongue (34.3%) were the most common sites involved. Total of 204/256 (79.6%) patient had some form of addiction which included both smoked and smokeless form of tobacco as the most common type of addiction. Among the tobacco smokers, 24/80 (30%) had pre malignant and malignant lesions while among tobacco chewers 37/76 (48.6%) had pre malignant and malignant lesions.</p><p class="abstract"><strong>Conclusions:</strong> Lesions of the oral cavity are common among Indian population due to high prevalence of tobacco addiction. A thorough history taking and examination can detect premalignant and malignant lesions at an early stage, so that timely treatment can reduce the mortality rates in such patients.</p>

Author(s):  
Mohammed Thoyyib ◽  
Roshni Menon ◽  
Brinda G. David

<p class="abstract"><strong>Background:</strong> Facial melanosis (FM) which refers to brown, black or blue pigmentation over the face is a common cosmetic concern in Indian patients. This increased incidence could be due to remarkable diversity of Indian ethinic population. Pigmentary disorders of the face are a great cosmetic and psychological concern for the patients.</p><p class="abstract"><strong>Methods:</strong> This is an extensive descriptive clinico epidemiological study comprising of 1024 patients, conducted at Sri Venkateshwara Medical College Hospital and Research Centre, Puducherry, for a period of one and a half years. A detailed clinical history and examination was done, and all the clinical photographs and data were recorded. Necessary investigations like skin biopsy and patch testing was done wherever required.<strong></strong></p><p class="abstract"><strong>Results:</strong> The maximum number of patients belong to the age group of 21-35 years with a female predominance (67.2%). Among patients of FM, post inflammatory pigmentation (35.3%) was the most common comprising of 362 patients, followed by melasma (17.2%), periorbital melanosis (15.7%), seborrheic melanosis (7.5%) followed by other causes.</p><p><strong>Conclusions:</strong> FM is common in Indian skin, several of which have overlapping features, and some have defined clinical classification. Additionally, climatic conditions, cosmetic usage and social parameters predispose to the increased incidence of FM.</p>


Author(s):  
Ramesh A. ◽  
Sampath V. ◽  
Shvedha M.

<p class="abstract"><strong>Background:</strong> Leprosy is a chronic infectious granulomatous disease caused by <em>Mycobacterium leprae</em>. The disease primarily affects peripheral nervous system, the skin and certain other tissues. It is a spectral disease which is classified into five groups based on clinical, histopathological and bacteriological and immunological criteria as tuberculoid (TT), borderline tuberculoid (BT), mid-borderline (BB), borderline lepromatous (BL), lepromatous (LL) according to Ridley-Jopling classification. Adequate clinical information combined with histopathology and bacteriological index is helpful not only in classification of different types of leprosy, but also useful for management of cases.The objective of the study was to correlate clinical diagnosis with histopathological findings of leprosy.</p><p class="abstract"><strong>Methods:</strong> A retrospective study was conducted for one year from January to December 2018 in Leprosy clinic, Department of Dermatology, Rajiv Gandhi Government General Hospital and Madras Medical College, Chennai. The histopathological findings were compared with clinical diagnosis.<strong></strong></p><p class="abstract"><strong>Results:</strong> A total number of cases attended leprosy clinic from January 2018 to December 2018 was 167 cases, among those 49 clinically diagnosed cases were included in the study. Out of 49 cases, maximum number of patients belonged to 30-50 years age group. Male to female ratio was 3.9: 1. Hypopigmented, hypoaesthetic patches were commonly seen. Clinically as well as histopathologically BT leprosy was common.The maximum histological correlation seen in lepromatous leprosy (100%) followed by BT (80%).</p><p class="abstract"><strong>Conclusions:</strong> The study emphasises the role of skin biopsy in confirming the clinical diagnosis of leprosy and also as a therapeutic guide.</p>


2017 ◽  
Vol 4 (3) ◽  
pp. 799
Author(s):  
Richa Garg ◽  
Ranjana Desai

Background: Cervical cancer in India ranks as the 2nd most frequent cancer among women and the 2nd most frequent cancer among women between 15 and 44 years of age. Invasive carcinoma of cervix is preventable as it is associated with pre-invasive stage which occurs 10-15 years prior to it, thus permitting early detection by screening and leading to effective treatment and thereby reducing mortality rate with greater impact on lives saved. Objectives were to correlate the findings of Pap smear with colposcopy in evaluation of all symptomatic women; and to assess the utility of colposcopy in detecting the premalignant and malignant lesions of cervix.Methods: This was a prospective observational study of 200 symptomatic women attending the Gynecology OPD of Umaid Hospital Dr. S. N. Medical College Jodhpur, Rajasthan, India from February 2015 to October 2016. Evaluation of all symptomatic women done with Pap smear, colposcopy and biopsy in selected cases and findings were noted.Results: Commonest complaint was white discharge per vaginum in 58.5% followed by pelvic pain in 24% women. 8% women had abnormal pap smear findings with 4% of women had ASCUS, 0.5% had ASC-H, 3% had LSIL and 0.5% had HSIL,73% had inflammatory and 19% with normal smear. 38.5% had abnormal colposcopy with maximum 28% women had acetowhite lesions. Sensitivity of pap smear was 44.44% while sensitivity of colposcopy was 88.88%.Conclusions: Pap smear had poor sensitivity as compared to colposcopy. Hence simultaneous use of colposcopy has shown to increase in the rate of carcinoma cervix detection in symptomatic women.


Author(s):  
Pratibha Garg ◽  
Urmila Tripathi

Background: Pregnancy poses unique consideration for critical care and it is imperative that obstetrician and other members of health care team have a working knowledge of these factors because these are women are usually young and in good health, their prognosis should be better than that of many other patients admitted to an intensive care.Methods: The present study was conducted in the Department of Obstetrics and Gynaecology, Gaja Raja Medical College and associate Kamla raja Hospital, Gwalior in the ICU from Oct. 14 to Oct. 15.Results: 678 obstetric women were admitted into the ICU of Kamla Raja Hospital, over a period of 1 year study period. Maximum number of patients belong to age group 21-25 years (54.8%), 398 (58.7%) patients were uneducated, 343 (50.59%) came directly to Kamla Raja Hospital. 362 (53.39%) belongs to urban area. The mean length of stay in ICU was 3 days. Maximum number of patients were postpartum 580 (85.55%). According to mode of delivery maximum number of patients 348 (51.33%) underwent LSCS. Most common obstetric indication for admission in ICU was hypertensive disorder of pregnancy 472 (69.61%). Most common medical indication was severe anaemia 128 (18.87%). Various type intervention like pulse oxymetry, O2 inhalation, BT, nebulisation and ventilation were done in ICU according to patients need. 43 maternal death happened during the study period with most common cause was cardiorespiratory arrest 9 (1.32%) and pulmonary edema 8 (1.17%).Conclusions: Establishment of a dedicated obstetric ICU at tertiary care centre with knowledge familiarity, experience and expertise of an obstetrician and a special team would be best place to monitor and treat the critically ill obstetric patients which will reduce the maternal morbidity and mortality.


Author(s):  
MK Mohan Kumar ◽  
M.S. Vinodkumar ◽  
, Indu

<div><p><em>According to WHO in 2010, an estimated 270000 deaths globally were attributable to congenital anomalies during first 28 days of life. In an effort to decrease the number of congenital anomalies worldwide, 63<sup>rd</sup> the WHO adopted a birth defects resolution. The aim was to prevent congenital anomalies and raise awareness about their effects. Hospital based surveillance was implemented in India in collaboration with WHO. Institute of Maternal and Child Health (IMCH), Govt. Medical College Kozhikode was selected from the state of Kerala. Aim of this study includes, monitor and detect clusters (outbreaks) of congenital anomalies among a defined population and refer affected infants to appropriate services in a timely manner. Out of 15519 live births and 409 still births during the period of one year from November 2015 to 2016, there were 123 newborns with selected external congenital anomalies. </em><em></em></p></div>


Author(s):  
Shaveta Garg ◽  
Naina Kumar

Background: Intrauterine fetal death (IUFD) is a tragic event for both the parents and obstetrician. Objectives of current study were to study the underlying etiology of Intra Uterine Fetal Death (IUFD) that can be helpful in formulating the preventive measures.Methods: This study was conducted over a period of one year from April 2016 till March 2017 at a tertiary rural care hospital. All patients with diagnosed IUFD at >24 weeks of gestation were included in the study.Results: Total eighty patients were admitted with diagnosis of intrauterine fetal death. Among these majority 58 (72.5%) were multigravida and only 22 (27.5%) were primigravida. Maximum number of patients, 61 (72.5%) were between age group of 20-30 years. Maximum number of IUFD were reported between 36-40 weeks of gestation (36.25%). Most of fetal deaths were due to preventable conditions like hypertensive disorders of pregnancy (28.75%), severe anemia (15%), abruptio placenta (11.25%), and rupture uterus (10%). Out of these patients 68 (85%) delivered vaginally and 7 patients were delivered by LSCS.Conclusions: The present study emphasizes the role of health education, regular antenatal checkups, early detection of complications and hospital delivery to reduce the overall preventable IUFD.


Author(s):  
Syed Tanwir Alam Samrat Biswas ◽  
Kalpana Bezborah Sonuwara Begum ◽  
Mihirjyoti Pathak Saurav Phukan ◽  
Pitambar Baishya Kaushik Das ◽  
Jasbeer Singh Roy Sanjay Sarkar ◽  
...  

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) which is also called COVID-19 has affected millions of people globally and has led to unprecedented disruptions to health systems, as well as affected individuals social, economic and psychological lives very badly. The present study was an attempt to address the association between age and gender among positive COVID-19 cases and also to discuss the possible reasons for the variation among age categories and gender. This was a retrospective based study. Samples were collected in Viral Transport Media and sent to the testing laboratory for confirmation by nucleic acid–based reverse transcription polymerase chain reaction (RT-PCR). Data regarding patients’ details were collected in the hospital facility. A total of 1,11,379 (Assam - 1,08,836 and Arunachal Pradesh-2543) samples were collected from patient’s and tested for COVID-19 (April to December 2020). During this period a total of 2,600 positive cases were detected at the laboratory from Assam (n= 2,480, 95.38%) and Arunachal Pradesh (n= 120, 4.62%) respectively. Males (n=2106, 81%) was affected more than females (n= 494, 19%). In both male & female the age group which was affected the most was between 20-29 yrs and 30-39 yrs. Month wise distribution of the positive COVID-19 cases showed maximum spike in the month of August (n=902). Early diagnosis by real time PCR has helped in the identification of the pathogen in individuals at an early stage, which has facilitated the containment of positive cases.


2019 ◽  
Vol 6 (3) ◽  
pp. 724
Author(s):  
Shashank Shekhar Tripathi ◽  
Ankur Tripathi ◽  
Rahul Singh ◽  
Himansha Pandey

Background: Surgical wound infection is a common post-operative complication causing significant post-operative morbidity and mortality, prolonged hospital stays and adds between 10-20% to hospital cost.Methods: This is a prospective study conducted in Department of General Surgery and Department of Microbiology, M.L.N. Medical College and Swaroop Rani Nehru Hospital, Allahabad. The study group comprised of all patients who underwent surgery during the period from October 2017 to September 2018 and were diagnosed with postoperative surgical site infection and wound dehiscence.Results: A total of 1640 patients were followed during one year of study. 540 (32.92%) patients were operated as emergency cases while 1100 (67.08%) were operated as elective cases.Conclusions: Wound dehiscence is a common surgical complication occurring in about 6.5% of surgical procedures. Emergency operative procedures are associated with higher incidence (16.67%) of wound dehiscence as compared to elective surgical procedures (1.67%). Male gender is more commonly associated with wound dehiscence especially in case of emergency surgical procedures with male to female ration of 1.67:1.Incidence of wound dehiscence increases with increasing age being maximum in older age group. Malnutrition is the most common risk factor present in surgical patients predisposing to wound dehiscence.


Author(s):  
Shairoly Singh ◽  
Ishan Arora ◽  
Shireen Singh

Background: In India, a large majority of blood donors are deferred due to anemia. Anemia is a temporary cause of deferral which can be easily treated. Deferrals due to anemia can be easily identified in blood bank and can be treated and managed effectively.Methods: A retrospective study was carried out in Department of Blood Bank of Pt. Jawahar Lal Nehru Govt. Medical College, Chamba (H.P) over a time period of one year from 1st Jan 2017 to 31st Dec 2017.Results: We observed that the total number of deferrals was 90 out of all blood donors forming 9%. Out of all deferrals, those due to anemia were 23 (25.5%). Prevalence of anemia in female donors is much higher, constituting 26.31% and anemia in male donors in our study is lower forming 1.8%.Conclusions: Our study concluded that percentage of anemia is much higher in females than males. Educating and counseling females about prevention and treatment of anemia would help in lowering the percentage of anemia in females in our community.


2017 ◽  
Vol 18 (2) ◽  
pp. 6-10
Author(s):  
Dipesh Kumar Gupta

Introduction: Quantification of lower urinary tract symptoms (LUTS) in patients with benign enlargement of prostate (BEP) is required to initiate and regulate treatment. Among many, International Prostate Symptom Score (IPSS) is standard though it is time consuming and difficult to understand by many patients. A recent Visual Prostate Symptom Score (VPSS) which is presumed to be simpler and well understood by patients with lower educational status has been in use.Methods: This is a prospective observational study conducted in Nepalgunj Medical College, Nepalgunj. In a total of 79 patients, 25 patients of LUTS because of other causes were excluded and 54 patients clinically diagnosed with BEP were enrolled for the study over a period of one year. Symptom evaluation was done in all with both IPSS and VPSS and uroflowmetry parameters were also recorded. The IPSS and VPSS were compared with each other and also with uroflowmetry parameters.Results: Mean age of the patients was 67 years and mean prostate volume was 48 gm. The patients who mostly were farmers had median eighth grade of education. Fourteen were illiterates and 40 were literate patients. Significant number of patients required assistance of a medical personnel to complete IPSS (p= <0.001) including those in literate group as well (p= <0.001). Time taken to complete VPSS was significantly less (p= 0.019). Total IPSS correlated with total VPSS ((r= +0.36; p=0.007). There was negative and significant correlation of VPSS with uroflowmeter parameters while IPSS failed to do so.Conclusion: VPSS is an easy and reliable tool to assess symptom severity in cases of BEP presenting with LUTS. It has the added advantage of utility in assessment of LUTS in patients with lower educational status. Moreover, the patients take shorter time to complete the questionnaire.  Journal of Society of Surgeons of Nepal, 2015; 18 (2), page: 6-10


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