scholarly journals A study on assessment of postoperative complications among major abdominal surgeries using Clavien-Dindo classification

2020 ◽  
Vol 7 (6) ◽  
pp. 1788
Author(s):  
Rohit Reddy Rapaka ◽  
Venkata Reddy M.
Keyword(s):  
Abdominal Surgery ◽  
Age Group ◽  
Clinical Value ◽  
Exclusion Criteria ◽  
Standard Clinical Practice ◽  
Operative Complications ◽  
Postsurgical Complication ◽  
Low Incidence ◽  
Case Number ◽  
Definite Statement

Background: Surgical team always tries to provide consistently low incidence of major complications for patient undergoing any operation. Clavien-Dindo (CD) classification is the simplest way of reporting all complications. The main aim of this study was to test the usefulness of Clavien-Dindo classification in patients undergoing the abdominal surgery. In this study Clavien-Dindo classification has been used for assessment of postsurgical complications after major abdominal surgery.Methods: A total of 50 patients admitted to surgical wards for major abdominal surgery were evaluated through history, co-morbid condition and thorough clinical examination based on inclusion and exclusion criteria along with necessary investigations. Post-operative complications and management were recorded, and then postsurgical complication was classified based on Clavien-Dindo classification and assessed.Results: Most of the patients who developed complications were in the age group of 40-50 years. Most of the patients (32%) belonged to grade 2 complications. Serum creatinine, blood urea and post-operative stay were found to have direct relation with Clavien-Dindo grade of complications.Conclusions: The Clavien-Dindo classification represents an objective and simple way of reporting all complications in patients undergoing major abdominal surgeries and comparing the various complications between different surgeries. However, a definite statement on the clinical value of this classification system is not yet possible due to the small case number in this study, but the promising results should encourage further evaluation in larger cohort with the goal to possibly establish its validity as a standard clinical practice. 

Monocyte distribution width (MDW): a useful biomarker to improve sepsis management in Emergency Department

2022 ◽  
Vol 0 (0) ◽  
Author(s):  
Donatella Poz ◽  
Danila Crobu ◽  
Elena Sukhacheva ◽  
Marco Bruno Luigi Rocchi ◽  
Maria Chiara Anelli ◽  
...  
Keyword(s):  
Emergency Department ◽  
Clinical Decision Making ◽  
Area Under The Curve ◽  
Sepsis Group ◽  
Differential Analysis ◽  
Clinical Value ◽  
Sepsis Management ◽  
Distribution Width ◽  
Standard Clinical Practice

Abstract Objectives Sepsis is a time-dependent and life-threating condition. Despite several biomarkers are available, none of them is completely reliable for the diagnosis. This study aimed to evaluate the diagnostic utility of monocyte distribution width (MDW) to early detect sepsis in adult patients admitted in the Emergency Department (ED) with a five part differential analysis as part of the standard clinical practice. Methods A prospective cohort study was conducted on 985 patients aged from 18 to 96 and included in the study between November 2019 and December 2019. Enrolled subjects were classified into four groups based on sepsis-2 diagnostic criteria: control, Systemic Inflammatory Response Syndrome (SIRS), infection and sepsis. The hematology analyzer DxH 900 (Beckman Coulter Inc.) provides the new reportable parameter MDW, included in the leukocyte 5 part differential analysis, cleared by Food and Drug administration (FDA) and European Community In-Vitro-Diagnostic Medical Device (CE IVD) marked as early sepsis indicator (ESId). Results MDW was able to differentiate the sepsis group from all other groups with Area Under the Curve (AUC) of 0.849, sensitivity of 87.3% and specificity of 71.7% at cut-off of 20.1. MDW in combination with white blood cell (WBC) improves the performance for sepsis detection with a sensitivity increased up to 96.8% when at least one of the two biomarkers are abnormal, and a specificity increased up to 94.6% when both biomarkers are abnormal. Conclusions MDW can predict sepsis increasing the clinical value of Leukocyte 5 Part Differential analysis and supporting the clinical decision making in sepsis management at the admission to the ED.

scholarly journals A STUDY ON PATTERN OF PRESCRIBING MEDICATIONS USED IN SECONDARY PREVENTION OF STROKE

2016 ◽  
Vol 9 (9) ◽  
pp. 328
Author(s):  
Lakshmi R ◽  
Jithin Kc ◽  
Arya G ◽  
Lekshmi P Nair
Keyword(s):  
Diabetes Mellitus ◽  
Secondary Prevention ◽  
Tertiary Care ◽  
Age Group ◽  
Data Collection Form ◽  
Comorbid Conditions ◽  
Exclusion Criteria ◽  
Prescribing Pattern ◽  
Number Of Patients ◽  
Collection Form

ABSTRACTObjectives: The main objectives of this study were to estimate the demographic details of patients with the first incidence of stroke and to study thevarious risk factors for ischemic stroke.Methods: It was a retrospective, observational study carried out for 1 year at the Department of Stroke Medicine of a tertiary care teaching hospitalin Kerala, India. A total of 636 patients were admitted under stroke medicine during the period from July 1, 2014, to July 1, 2015, and who satisfiedthe inclusion and exclusion criteria were included in the study. A standardized data collection form was prepared and necessary data were collectedfrom patient’s medical records.Results: The maximum number of patients was in the age group of 60-69 years. 65.1% patients were residing in the rural area. 60.7% patients weremale. Most of them had hypertension as common comorbidity (21.35%) and the highest number of patients had diabetes mellitus and hypertension(21.7%). Majority of the patients were prescribed with antiplatelets (94.91%), followed by statins (93.8%).Conclusion: A strict control on the comorbid conditions and sticking on to the medications can prevent the occurrence of future stroke.Keywords: Stroke, Secondary prevention, Drugs, Prescribing pattern.

scholarly journals Helicobacter pylori infection and its correlates among the patients of peptic perforation and gastric carcinoma

2020 ◽  
Vol 7 (5) ◽  
pp. 1518
Author(s):  
Subhendu Bikas Saha ◽  
Sabyasachi Bakshi ◽  
Tapas Mandal
Keyword(s):  
Gastric Carcinoma ◽  
High Frequency ◽  
Age Group ◽  
Morbid Condition ◽  
Exclusion Criteria ◽  
Chronic Alcoholic ◽  
Female Ratio ◽  
History Of ◽  
Study Population ◽  
H Pylori

Background: Presence of H. pylori infection was found associated with peptic perforation and gastric carcinoma. Present study tried to estimate the prevalence of H. pylori infection in those patients and to find out the correlates of H. pylori infection.Methods: After matching the inclusion and exclusion criteria, all cases of diagnosed peptic perforation and gastric carcinoma were taken for this prospective, single center, observational study.Results: Among the study population, gastric carcinoma was found in higher age group; whereas peptic perforation was found in lower age group; male and female ratio was 2:1 in both groups of patient. Laborer and housewives were mostly affected in both cases. Gastric carcinoma was more prevalent in urban residents, opposite was seen in peptic perforation. Most patients in two groups had no previous co-morbid condition. Use of NSAIDs was found in high frequency in both groups. Most of the patients were chronic alcoholic and chronic smoker, and most of them had history of taking spicy foods more than twice in a week.Conclusions: H. pylori infection was found in high frequency in both group of patients, and it was higher in peptic perforation. The study establishes the association of H. pylori with the gastric carcinoma and peptic perforation.

scholarly journals Epidemiological study, clinical spectrum and associations of childhood vitiligo in a tertiary care centre

2016 ◽  
Vol 2 (4) ◽  
pp. 86
Author(s):  
Rangaraj Murugaiyan
Keyword(s):  
Tertiary Care ◽  
Significant Proportion ◽  
Clinical Spectrum ◽  
Age Group ◽  
Care Centre ◽  
Inclusion Criteria ◽  
Common Site ◽  
Tertiary Care Centre ◽  
Exclusion Criteria ◽  
The Past

<p class="abstract"><strong>Background:</strong> <span lang="EN-IN">Childhood vitiligo is a special subtype and is seen in significant proportion of vitiligo patients. There are only a few clinical studies in the past which address the clinical spectrum of vitiligo in children. This study on eighty cases of childhood vitiligo will cover the epidemiology and clinical spectrum.</span></p><p class="abstract"><strong>Methods:</strong> To study the epidemiology, clinical spectrum and associations in childhood vitiligo. Inclusion criteria: all new cases of vitiligo in children under 12 years attending the outpatient department of Dermatology, exclusion criteria: old treated cases of vitiligo and age more than 12 years. Statistical analysis was done using mean and percentage of means.<strong></strong></p><p class="abstract"><strong>Results:</strong> <span lang="EN-IN">Most common age group affected includes 4-6 years. Most common site of initial lesion was head and neck followed by upper limb, lower limb and trunk. Most common clinical type was vitiligo vulgaris followed by focal type then segmental. Lip tip type was least common type. </span></p><p class="abstract"><strong>Conclusions:</strong> <span lang="EN-IN">Childhood vitiligo is a serious issue and the knowledge of its various patterns and associations needs to be updated at regular intervals.</span></p>

Continuous suturing as a wound closure technique for circumcisions

2019 ◽  
Vol 12 (6) ◽  
pp. 470-473
Author(s):  
Manoj Ravindraanandan ◽  
Herman Fernando ◽  
Shahjahan Aslam
Keyword(s):  
Male Circumcision ◽  
Wound Closure ◽  
Suture Technique ◽  
Complication Rates ◽  
Continuous Suture ◽  
Single Institution ◽  
Closure Technique ◽  
Level Of Evidence ◽  
Operative Complications ◽  
Low Incidence

Male circumcision is an extremely common urological procedure worldwide, with many variations in technique. Despite the large volume there is a low incidence of complications associated with circumcisions, with the majority being Clavien-Dindo I or II. In this study, we analyse the outcomes and complication rates associated with a continuous wound closure following a male circumcision. Methods: In a urology department from a single institution, 201 male circumcisions with a continuous wound closure were performed in a 4-year period. Outcomes were analysed retrospectively looking at postoperative complications and readmissions to hospital via our clinical portal. Results: No patients had complications that required admission or re-operation at our institution. Conclusion: No major post-operative complications were observed from our cohort. There were also no documented admissions back to our institution with wound healing complications. However, a limitation is that Clavien-Dindo I and II complications and treatment at general practitioner surgeries were not captured and may not accurately represent our complication rates quoted. Nevertheless, we can conclude from these data that closure for a circumcision using a continuous suture technique gives favourable outcomes with acceptable complication rates. Level of evidence: Not applicable for this multicentre audit.

Clinicoepidemiology and treatment outcome of acute intestinal obstruction in adult in KIMS Amalapuram: a retrospective observational study

2020 ◽  
Vol 7 (12) ◽  
pp. 4139
Author(s):  
Y. Anantha Lakshmi ◽  
K. V. Narasimha Reddy
Keyword(s):  
Intestinal Obstruction ◽  
Acute Intestinal Obstruction ◽  
Age Group ◽  
Exclusion Criteria ◽  
Common Procedure ◽  
Case Record ◽  
Common Etiology ◽  
The Mean ◽  
Study Case ◽  
Surgical Admission

Background: The intestinal obstruction is a common potentially risky surgical emergency in all age group globally. This is responsible for 12% to 15% of surgical admission due to acute abdomen. Obstruction to gastrointestinal tract can occur at all labels but it is small intestine which more commonly involved. To improve the outcome early diagnosis and management is essential. Present study has been designed to study the epidemiology, demography and clinical presentation of acute intestinal obstruction and to study the complications and outcome of surgical management of acute intestinal obstruction.Methods: In present study patients admitted with diagnosis of acute intestinal obstruction during study period were enrolled for this study as per inclusion and exclusion criteria. As per that 126 patients were enrolled for this study. Case record of all patients were closely reviewed and analysed thoroughly.Results: The mean age of the patients was 54.64±12.93 years. The acute intestinal obstruction was more common in 41 to 60 years of age group that is (44.45%). Regarding etiology of acute intestinal obstruction 44.45% patient adhesion was the etiology of obstruction. Resection of adhesion was most common procedure done for removal of obstruction (42.85%).Conclusions: Adhesion was most common etiology and pain abdomen and tachycardia was common presentation. Regarding management of obstruction resection of adhesion was most common procedure done for removal of obstruction. Infection of wound was common complication.

Characteristics of stage III and IV M0 prostate cancer (PCa) patients in SEER-Medicare who develop bone metastasis (BM) following diagnosis.

2012 ◽  
Vol 30 (15_suppl) ◽  
pp. e15146-e15146
Author(s):  
Arif Hussain ◽  
Ebere Onukwugha ◽  
Jinani Jayasekera ◽  
Diane L. McNally ◽  
Brian S. Seal ◽  
...  
Keyword(s):  
Stage Iv ◽  
Patient Characteristics ◽  
Stage Iii ◽  
Age Group ◽  
Diagnosis Code ◽  
Exclusion Criteria ◽  
Chi Square ◽  
Medicare Database ◽  
Stage Stage

e15146 Background: BM is diagnosed in 70-80% of men with metastatic PCa. Less is known about the timing of BM diagnosis following incident non-metastatic PCa and associated patient characteristics. In this study, we determined the incidence and timing of post-diagnosis BM (BMpd) among PCa patients (pts) by incident stage, age, race and year of diagnosis using a large observational dataset. Methods: We analyzed pts aged 66 or older from the linked Surveillance, Epidemiology, and End Results and Medicare (SEER-Medicare) database. Pts with PCa were identified between 2000 and 2007 and were followed until death, Medicare disenrollment, HMO enrollment, or end of the study (December 31, 2009). The cohort included incident stage III and IV(M0) PCa in SEER, and identified BM occurring either within (i.e., +/-) 1 month of the SEER diagnosis month (BM90) or beyond the initial 90-day window (BMgt90) based on the presence of at least one inpatient or one outpatient claim with a diagnosis code of 198.5. We calculated summary and chi-square statistics to examine BMpd, BM90, and BMgt90 by incident stage, age, race and year of PCa diagnosis. Results: Among 9,188 Stage III (72%) and IV(M0) (28%) PCa pts who met inclusion/exclusion criteria, 14.6% (n=1,345) had BMpd: 2.3% (n= 217) had BM90 and 12.3% (n=1,128) had BMgt90. Average age was 72 years and 9% were African American (AA). Incidence of BMpd varied by stage (stage III: 11%; stage IV/M0: 25%; p<0.001) and by age group (66-74 years: 13%; 75-84 years: 19%; >85 years: 22%; p<0.001) but not by race (White: 15%; AA: 16%; Other: 13%; p=0.49). The diagnosis BM90 and BMgt90 varied with stage (stage III: 2% and 9%; stage IV(M0): 4% and 21%; p<0.0001) and age (66-74 years: 2% and 11%; 75-84 years: 3% and 16%; >85 years: 5% and 17%; p<0.001). The incidence of BM decreased over time whether considering BMpd (19% in 2000 to 9% in 2007; p<0.001), BM90 (4% in 2000 to 2% in 2007; p=0.03) or BMgt90 (16% in 2000 to 6% in 2007; p<0.001). Conclusions: BM occurred in only 2% of incident stage III/IV(M0) PCa pts within 1 month of diagnosis, but nearly 15% were diagnosed with BM during a median follow-up of 57 months. Prevalence of BM was highest in stage IV(M0) and older pts.

scholarly journals A study of clinical evaluation and management of inguinoscrotal swelling in paediatric age group

2018 ◽  
Vol 5 (6) ◽  
pp. 2097
Author(s):  
Himadra Koranga ◽  
R. Chandrasekaran
Keyword(s):  
Undescended Testis ◽  
Surgical Repair ◽  
Emergency Operation ◽  
Age Group ◽  
Infancy And Childhood ◽  
Operative Complications ◽  
Paediatric Age ◽  
Hernia Inguinal ◽  
Scrotal Swelling ◽  
Post Operative Complications

Background: Inguino-scrotal swellings are one of the commonest problems in infancy and childhood throughout the world. They represent the conditions most frequently requiring surgical repair in the paediatric age group.  In many of these cases, clinical examination may suffice to obtain a definite diagnosis, but when the diagnosis is inconclusive, ultrasonography can play an important role. Post-operative complications are usually rare following elective operation whereas minor complications do occur after emergency operation. In this study we evaluated various presentations of inguino-scrotal swellings, their management and complications in paediatric age group.Methods: This is a hospital based prospective study, to have an overview of a spectrum of the paediatric cases admitted in the department of surgery with inguino-scrotal swelling that includes 40 patients with age below 13 years, irrespective of sex. Data regarding clinical features, birth history, immunization, family history various blood and radiological investigations was noted. Incidences of associated anomalies, complications and any form of treatment given to the patient were recorded and findings were analysed.Results: Out of 40 cases, all were males with maximum number of cases between the age group of 3-4 years.24 cases were right sided, 12 left sided and 4 bilateral. Hydrocele was associated with 10 of the cases, undescended testis with 2 cases and 1 had encysted hydrocele of the cord. There were no complicated cases like incarceration, obstruction or strangulation. Post-operative complications were noted in 4 cases, out of which 2 were wound haematoma and one case each of wound infection and stitch granuloma.Conclusions: Childhood inguinal hernias are more common on right side due to delay in descent of right testis and males are more commonly affected. Congenital hydrocele may involutes spontaneously, so we should observed at least upto 1 year of age before considering repair but not in the case of congenital inguinal hernia. Inguinal herniotomy in children is a safe and effective operation.

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