scholarly journals Clinical profile of typhoid fever in children at a tertiary care hospital: a cross sectional study

2017 ◽  
Vol 4 (6) ◽  
pp. 1951
Author(s):  
Siddiqui S. S. ◽  
Shivraj Kumar Koppa ◽  
Kale A. V.
Keyword(s):  
Typhoid Fever ◽  
Urban Areas ◽  
Enteric Fever ◽  
Clinical Presentation ◽  
Tap Water ◽  
Tertiary Care ◽  
Clinical Signs ◽  
Signs And Symptoms ◽  
Drinking Water Source ◽  
Care Hospital

Background: In endemic areas such as India, traditional signs and symptoms in enteric fever are not often observed. Unusual presentations lead to diagnostic dilemma and may delay the diagnosis of typhoid fever. The present study describes the clinical presentation of enteric fever at a tertiary care centre in Aurangabad district of Maharashtra.Methods: The study was a hospital based prospective observational study done in paediatric ward of MGM Medical College, Aurangabad over a period of 18 month starting from 1st November 2013 to 31st April 2015. The parents of the children were informed about the research and its objectives, and written informed consent was obtained from them. Prior approval was taken from institutional ethics committee.  Children of age 2 -18 years who presented with fever of 5 days or more with clinical signs and symptoms suggestive of typhoid fever and positive Widal test or Typhidot tests were included in the study. The demographic and clinical features of the patients were described.Results: Total of 99 patients were included in the study. Majority of the children were between 2 - 7 year age group (45.4%). Out of 99 children, 57 were males and 42 were females. Majority of the cases were from urban areas accounting for 75%, which included urban slums. Drinking water source was tap water in 80% cases and bore well water in 20% cases. Only 36.4% of children had fever of less than one-week duration. 58.6% of the cases had fever of more than one week but less than two weeks. Continuous fever was noticed in majority of children (55.55%). All the children presented with fever as the main complaint (100%). Loss of appetite and headache were the next common complaints reported by 59.6% cases. Commonest sign noticed was toxic look (83.8%) followed by coated tongue (74.7%) and splenomegaly (61.6%). Hepatomegaly was also noted in 39.4% of cases.Conclusions: Clinical presentation in the study subjects was similar to available reports from literature.

scholarly journals CLINICAL PROFILE OF TYPHOID FEVER IN CHILDREN

2021 ◽  
Vol 5 (8) ◽  
Author(s):  
Shaitan Singh Balai
Keyword(s):  
Typhoid Fever ◽  
Enteric Fever ◽  
Tertiary Care ◽  
Clinical Signs ◽  
Signs And Symptoms ◽  
Clinical Profile ◽  
Care Hospital ◽  
Tertiary Care Centre ◽  
Main Complaint ◽  
Clinical Signs And Symptoms

Background: The present study describes the clinical presentation of enteric fever at a tertiary care centre. Methods: The study was a hospital based prospective observational study conducted on  children of age 2 -18 years who presented with fever of 5 days or more with clinical signs and symptoms suggestive of typhoid fever and positive Widal test or Typhidot tests were included in the study. The demographic and clinical features of the patients were described. Results: All the children presented with fever as the main complaint (100%). Commonest sign noticed was toxic look (84%) followed by coated tongue (79%) and splenomegaly (61%). Hepatomegaly was also noted in 34% of cases. Conclusion: This study was undertaken to observe the clinical profile of typhoid fever in children admitted in a tertiary care hospital. Typhoid fever remains to be as an endemic disease in this locality. All the signs and symptoms of the disease are nonspecific common with other acute febrile illnesses; a definitive diagnosis of the disease is required for treatment and to prevent transmission. Keywords: Enteric fever, Splenomegaly, Toxic look

scholarly journals CLINICAL PROFILE OF TYPHOID FEVER IN CHILDREN

2021 ◽  
Vol 5 (12) ◽  
Author(s):  
Poonam Meena ◽  
Satish Meena ◽  
Ashok Meena ◽  
Kailash Meena
Keyword(s):  
Typhoid Fever ◽  
Prospective Study ◽  
Enteric Fever ◽  
Clinical Presentation ◽  
Clinical Signs ◽  
Signs And Symptoms ◽  
Definitive Diagnosis ◽  
Clinical Profile ◽  
Widal Test ◽  
Clinical Signs And Symptoms

Background: The present study describes the clinical presentation of typhoid fever. Methods: The study was a hospital based prospective study. Children of age 2 -18 years who presented with fever of 5 days or more with clinical signs and symptoms suggestive of typhoid fever and positive Widal test or Typhidot tests were included in the study. Results: Commonest sign noticed was toxic look (88.00%) followed by coated tongue (79.00%) and splenomegaly (63.00%). Hepatomegaly was also noted in 35.00% of cases. Conclusion: Typhoid fever remains to be as an endemic disease in this locality. All the signs and symptoms of the disease are nonspecific common with other acute febrile illnesses; a definitive diagnosis of the disease is required for treatment and to prevent transmission. Keywords: Enteric fever, Splenomegaly, Toxic look

scholarly journals Clinical profile and antibiotic sensitivity pattern of typhoid fever in children: a hospital based prospective study from a tertiary care center

2020 ◽  
Vol 7 (4) ◽  
pp. 901
Author(s):  
Shekar V. ◽  
Chapay Soren ◽  
Lakshmi Aparnadevi V. V. ◽  
Umadevi M. ◽  
Malathi Vanka
Keyword(s):  
Typhoid Fever ◽  
Clinical Presentation ◽  
Tap Water ◽  
Tertiary Care ◽  
Antibiotic Sensitivity ◽  
Public Health Problem ◽  
Clinical Profile ◽  
Drinking Water Source ◽  
Chloramphenicol Resistance ◽  
Sensitivity Pattern

Background: Typhoid fever is a serious public-health problem in many developing countries including India. There is a wide spectrum of clinical presentation and with the emergence of multidrug resistant typhoid now a days, the treatment has become still more complex. The present study authors describe the clinical profile and antibiotic sensitivity pattern of typhoid fever in children from a tertiary care in Mahabubnagar, Telangana, South India.Methods: This hospital based prospective observational study was done in Department of Pediatrics, SVS Medical College, Mahabubnagar, Telangana over a period of 3-year period from January 2017 to December 2019. The study was approved by institutional ethics committee. Written informed consent was obtained from children’s parents. All pediatric patients diagnosed as typhoid fever if presented with fever (temperature >38ºC) for at least 3 days with positive blood culture for S. typhi or paratyphi were included in the study. The demographic profile and clinical data were recorded and tests including antibiotic sensitivity and resistance were done.Results: A total of 136 patients were included in the study. Majority of the children were between 8 to 12-year age group (38.2%). Out of 136 children, 78 were males and 58 were females. Majority of the cases were from rural areas accounting for 69%. Drinking water source was tap water in 63% cases and bore well water in 37% cases. Majority (65%) belonged to lower socioeconomic class and 68% were during rainy seasons. The clinical findings observed were fever (100%), vomiting (98, 72%), diarrhea (55.8%), headache (45.5%), and splenomegaly (42.6%). Other clinical features found were coated tongue, abdominal pain, hepatomegaly, constipation, and dehydration. Six children had complications, 3 had enteric hepatitis, 2 had shock, and 1 had encephalopathy. Ampicillin, amoxicillin and chloramphenicol resistance was observed in 76%, 71% and 22% of patients with typhoid fever respectively. Maximum sensitivity was observed with ceftriaxone (95%), followed by aztreonam (92%), ciprofloxacin (84.5%), and azithromycin (77%).Conclusions: Clinical presentation in the study subjects was similar to available reports from literature. Increasing resistance of salmonella to Ampicillin and amoxicillin were observed.

scholarly journals Clinical, laboratory and radiological profile of dengue among pediatric patients admitted in tertiary care hospital

2018 ◽  
Vol 5 (6) ◽  
pp. 2237
Author(s):  
Sangeetha Jairaj ◽  
Sridhar D. ◽  
Mettu Pradeep Reddy
Keyword(s):  
Dengue Fever ◽  
Urban Areas ◽  
Health Personnel ◽  
Clinical Laboratory ◽  
Early Recognition ◽  
Tertiary Care ◽  
Clinical Signs ◽  
Signs And Symptoms ◽  
Severe Dengue ◽  
Care Hospital

Background: Dengue is found in tropical and subtropical regions around the world, predominantly in urban and semi-urban areas. Dengue mortality can be reduced by implementing early case detection and referral systems for patients; managing severe cases with appropriate treatment; reorienting health services to cope with dengue outbreaks; and training health personnel at all levels of the health system. Many studies that focus on the difference between the frequency of clinical findings in DHF and dengue shock syndrome (DSS) with respect to classical DF has been published. The objectives of the study were to assess signs and symptoms of dengue among patients with severe dengue and patients with dengue fever and to evaluate laboratory and radiological profile among dengue patients.Methods: This Hospital based cross sectional study was conducted on 70 seropositive cases, admitted in the Paediatrics Department of Gandhi hospital during the period of July to December 2017 for 6months. Data was analyzed by using SPPS Version 17 and student t test was used for inferential statistics.Results: Out of 70 cases 38 were presented with severe dengue and 32 presented with dengue fever. Average age of presentation is 7.24 years among severe dengue group, 5.52 years among dengue fever group. In group of severe dengue, 60.5% of the cases were female, which was insignificantly more as compared to 40.6% of the cases from group of dengue fever.Conclusions: All levels of health personnel must be aware of clinical signs and symptoms of all dengue types. Careful monitoring of unusual presentations early recognition severe manifestation and timely intervention can reduce disease specific mortality rate.

scholarly journals The Optimum Cut-off Value of the Nelwan Score to Diagnose Typhoid Fever in Adults

2021 ◽  
Author(s):  
Erni Juwita Nelwan ◽  
Luh Putu Listya Paramita ◽  
Robert Sinto ◽  
Fransiscus Nikodemus Hosea ◽  
Pringgodigdo Nugroho ◽  
...  
Keyword(s):  
Typhoid Fever ◽  
Clinical Presentation ◽  
Clinical Signs ◽  
Gastrointestinal Symptoms ◽  
Signs And Symptoms ◽  
Diagnostic Value ◽  
Cross Sectional Study ◽  
Cross Sectional ◽  
Clinical Signs And Symptoms ◽  
Sensitivity Specificity

AbstractIntroductionTyphoid fever can be challenging to diagnose since clinicians often depend merely on clinical presentation. Clinical scores are useful to provide more accurate diagnosis. Variables in Nelwan Score are derived from clinical signs and symptoms of suspected cases for typhoid. Diagnostic value of Nelwan Score based on a cut-off value has never been evaluated.MethodsA cross sectional study was conducted between July 2017 and January 2018 in five hospitals and two Primary Health Centers in Jakarta and Tangerang. The inclusion criteria were patients with 3-14 days of fever and gastrointestinal symptoms between July 2017 and January 2018. Diagnosis are confirmed by blood culture, rectal swab culture, or PCR. Cut-off analysis was performed by using Receiver Operating Characteristic (ROC) curve and diagnostic value was analyzed to generate sensitivity, specificity, predictive value and likelihood ratio.ResultFrom 233 subjects involved, 4.72% of them were confirmed to have typhoid fever. The optimal cut-off value of Nelwan Score is 10 with AUC 71.3%. This cut-off value has sensitivity 81.8%, specificity 60.8%, PPV 9.3%, NPV 98.5%, LR + 2.086, and LR – 0.299.ConclusionNelwan Score with cut-off value of 10 provides a good diagnostic performance as a screening tool for patients with suspected typhoid fever clinical presentation.

scholarly journals Study on ultrasound observations in children with typhoid fever in a tertiary care hospital

2020 ◽  
Vol 7 (2) ◽  
pp. 428
Author(s):  
Zubair Ahamed Md. ◽  
Gangadhar B. Belavadi
Keyword(s):  
Typhoid Fever ◽  
Enteric Fever ◽  
Tertiary Care ◽  
Wall Thickening ◽  
Age Difference ◽  
Care Hospital ◽  
College Hospital ◽  
Laboratory Findings ◽  
Female Ratio ◽  
Elevated Liver Enzymes

Background: Enteric fever continues to be endemic in poor countries globally, although it has been eradicated from the developed nations due to their well-organized sanitation and protected water supply. The five Fs most concerned with spread of typhoid disease are fingers, food, fomites, flies, and feces. Enteric fever is predominantly caused by Salmonella typhi and next in frequency is Salmonella paratyphi. Very less literature is available on radiological manifestations of typhoid fever in children on the basis of age difference in India. Hence, a study was conducted to observe the radiological findings and to correlate with laboratory manifestations in typhoid fever. Objectives of the study was to observe the ultrasound abdomen changes in Typhoid fever at rural area.Methods: The current study was conducted at Department of pediatrics of Narayana Medical College Hospital, Nellore, Andhra Pradesh state in a period of one year. All patients presenting with fever having positive for Widal test were included. In total 50 patients were included and divided into 2 age groups, <5 years and >5years. The laboratory results and abdominal ultrasound were conducted in the two groups and compared.Results: Total 20 patients in <5 years age and 30 patients in >5 years were enrolled. Male to female ratio was 2:1 in both groups. Common laboratory findings showed 32 patients (64%) with Anemia, elevated liver enzymes in 40 patients (80%), and elevated ESR in 42 patients (84%). 45 patients have Splenomegaly and hepatomegaly with normal parenchymal echotexture. Gallbladder sludge and biliary sludge was seen in 6 patients. Thickened gall bladder in 34 patients (68%) was observed. Bowel wall thickening seen in 32 patients (64%). mesenteric lymphadenopathy in 36 patients (68%) observed. All were recovered by treatment.Conclusions: On ultrasound, splenomegaly, hepatomegaly, and thick-walled gallbladder were observed in most of the childrens with typhoid fever. Therefore, ultrasound can also be used as supportive diagnose along with laboratory parameters due to it is a non-invasive and economical tool of diagnosing typhoid.

scholarly journals Frequency of complication, outcome and immunization of patients presenting with measles in a tertiary care hospital

2017 ◽  
Vol 1 (1) ◽  
pp. 30
Author(s):  
Mussarat Ameer
Keyword(s):  
Causes Of Death ◽  
Clinical Presentation ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Signs And Symptoms ◽  
Effective Vaccine ◽  
Care Hospital ◽  
Paediatric Ward ◽  
Paediatric Unit ◽  
Serious Disease

Introduction: Measles is a highly contagious, serious disease caused by a virus. The disease remains one of the leading causes of death among young children globally, despite the availability of a safe and effective vaccine. Objective: To describe the  frequency of complication, outcome and immunization of patients presenting with measles in a tertiary care hospital. Method: this pilot study is being conducted in  paediatric unit II, Abbasi Shaheed Hospital, Karachi from April to December 2016 among patients presenting with measles. All patients who presented with signs and symptoms suggestive of measles according to WHO criteria were included. Data  regarding demographic profile, duration of stay, clinical presentation, degree of  malnutrition, complication and outcome was collected and analyzed. Result: A total of 106/900 (12%) hospitalized patients with/without complications were included in this study. Out of 106 patient, 55(52%) were male and 51(48%) were females, the age group range was 4 months to 9 year. Patients shifted to P.I.C.U were 20(19%) of which 5(5%) expired and 15 were shifted to paediatric ward. Majority of the patients were incompletely vaccinated 52(49%), unvaccinated 28(26%), and 26 (24%) were completely vaccinated. The most common complication was pneumonia; followed by acute gastroenteritis, encephalitis, conjunctivitis, croup, dysentery, stomatitis,  pneumothorax. Majority of the patients Conclusion: Measles is still a serious threat to children in our population. The current study concluded that improving        immunization and nutritional status in children is essential for reducing morbidity and mortality.

scholarly journals Emerging hazard for women of new era: ovarian malignancy.

2021 ◽  
Vol 28 (09) ◽  
pp. 1229-1233
Author(s):  
Khadija Saleem ◽  
Tabinda Roheen ◽  
Faiza Wattoo ◽  
Sadia Ijaz ◽  
Farhan Javed ◽  
...  
Keyword(s):  
Malignant Tumors ◽  
Tertiary Care ◽  
Clinical Signs ◽  
Signs And Symptoms ◽  
Benign Tumors ◽  
Care Hospital ◽  
Duration Of Symptoms ◽  
Study Results ◽  
Clinical Signs And Symptoms ◽  
Mucinous Cystadenomas

Objective: The present study aims to assess the incidence of ovarian malignancies and its rise from 2010 to 2020 at subnational levels in tertiary care hospital in Faisalabad. Study Design: Retrospective Analysis. Setting: Madina Teaching Hospital, Faisalabad. Period: January 2010 and January 2020. Material & Methods: After the precise processing of data extracted from the Pakistan Cancer Registry and hospital records, annual standardized incidence and increasing trends were calculated during the period of the study. Results: A total of 103 patients of ovarian tumors were included in the study. During this period 550 oophorectomies were received out of 4752 (11.5%) gynecological admissions. 103 cases(18.73%) selected after formulating an inclusion criteria. The data showed 75 benign (74.25%) cases, 7 borderline tumors (6.93%) and 21 malignant tumors (20.79%). Age of patients ranged from 14-69 years. Out of all the benign tumors, serous cystadenomas were most common (45.33%) followed by mucinous cystadenomas (24%), dermoid cyst (30.66%). Commonest malignant tumor was serous cystadenocarcinoma (42.85%) followed by mucinous cystadenocarcinoma (33.33%) granulosa cell tumors (14.28%) krukenberg tumor (4.76%) and dysgerminoma (4.76%). Clinical signs and symptoms were mostly abdominal pain and distention. Conclusion: Ovarian malignancies are increasing in frequency at an early age with relatively longer duration of symptoms. This emphasizes the need of early detection and management because of desirability of maintaining patient’s menstrual and reproductive capabilities.

scholarly journals Clinical and biomarker profile of COVID-19 patients admitted in a tertiary care hospital

Biomedicine ◽  
2021 ◽  
Vol 41 (2) ◽  
pp. 268-273
Author(s):  
Archana Bhat ◽  
Don Gregory Mascarenhas ◽  
J Manjunath ◽  
Anand Kumar R ◽  
Sucharitha Suresh ◽  
...  
Keyword(s):  
Disease Severity ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Clinical Signs ◽  
Signs And Symptoms ◽  
Care Hospital ◽  
Male Predominance ◽  
Co Morbidity ◽  
Clinical Signs And Symptoms ◽  
D Dimer

Introduction and Aim:A novel beta-coronavirus emerged in Wuhan, China during the early December 2019 and spread globally. The clinical signs and symptoms and the disease severity in people infected with COVID-19 can be varied. The present study was conducted to study the biomarker profile and their association with disease severity in COVID-19.   Materials and Methods:This was a single-centre Cohort study of data regarding epidemiological, clinical and biomarker parameters, and outcome of COVID-19 patients admitted in a tertiary care hospital in South India. CDC guidelines were followed for assessing disease severity.   Results:A total of 336 COVID-19 patients were admitted during the study period. Of these 16 were excluded and 320 cases were analysed. Mean age of patients was 44.82 years. A male predominance was observed. Diabetes mellitus was the most common co-morbidity. Asymptomatic, Mild, moderate, severe and critical disease was seen in 15%, 52.5%, 20.3%, 6.3% and 5.9% patients respectively. ICU care was required in 15.3%. Overall mortality was 5.3%. The mean NLR, ALC, CRP, LCR, LDH, Ferritin and D-dimer in the severe group vs non-severe groupwere19.03 vs 4.2, 1025cells/cumm vs 1740cells/cumm, 185.8mg/L vs 31.7mg/L, 17.1 vs 996.3, 552.8IU/L vs 252.7IU/L, 2531.9ng/ml vs 414.1ng/ml and 2245.5ng/ml vs 339.4ng/ml respectively.   Conclusion:An increased NLR, CRP, LDH, Ferritin and D-dimer and a reduced ALC and LCR are significantly associated with disease severity, need for ICU and mortality. These biomarkers will be useful adjunct to clinical assessment in better categorising and management of COVID-19 patients.

A STUDY ON CLINICAL PROFILE AND OUTCOME OF SNAKE ENVENOMATION IN CHILDREN AT TERTIARY CARE HOSPITAL JHALAWAR, RAJASTHAN

2020 ◽  
Vol 4 (5) ◽  
Author(s):  
Abhishek Bansal ◽  
Kalu Ram Meena
Keyword(s):  
Tertiary Care ◽  
Clinical Signs ◽  
Public Health Problem ◽  
Pediatric Intensive Care ◽  
Signs And Symptoms ◽  
Snake Bite ◽  
Lower Limbs ◽  
Common Symptom ◽  
Care Hospital ◽  
Female Ratio

Background: Snake bite is generally considered to be a rural problem and has been linked with environmental and occupational condition is a neglected public health problem. Method: This study was conducted in children admitted with snake bite in Pediatric Intensive Care Unit in the year 2019. Their demographic details, site of bite, arrival time, 20Minutes Whole Blood Clotting time, clinical signs and symptoms, complications and outcome were measured. Results: The male: female ratio was 1.33:1. Peak age group affected was 6 to 12 years old children. Lower limbs were commonly bitten. 88.1% of children arrived in the hospital between 0 and 6 hours after the bite. Pain and swelling at the site of bite were the most common symptom of envenomation. There were only two deaths during the study period. Conclusion: Snake bite is a life threatening emergency. Identification, timely diagnosis and early administration of anti-snake venom will certainly aid to curb mortality in snake bite.

Sign in / Sign up

Export Citation Format

Share Document