scholarly journals Assessment of epidemiological profile of neonatal seizure cases admitted to a tertiary health center of Odisha, India: a cross-sectional study

2018 ◽  
Vol 6 (1) ◽  
pp. 181
Author(s):  
Geetanjali Sethy ◽  
Dhaneswari Jena ◽  
Pullakranjan Mallik ◽  
Sithun Kumar Patro ◽  
Biswakalyan Mishra

Background: Neonatal seizures are common manifestations of neurologic dysfunction in newborns. The incidence of  seizures in neonatal period is higher than any other period of life. It is one of the common causes of admission to special newborn care unit. Therefore, it has been decided to assess the epidemiological profile of neonatal seizure.Methods: A cross-sectional study was conducted from January2017 to June 2018, in the SNCU of MKCG Medical College and Hospital, Berhampur. A total of 300 neonates admitted to SNCU with clinically apparent seizure were the study population and convenient sampling method was used for selecting them. The approval was taken from IEC MKCG Medical College to carry out the study. The data was collected by using a pretested proforma from parents and hospital records. Verbal informed consent was taken from parents. The data so collected was analysed in the department of Pediatrics.Results: Out of the total 300 babies, 66% were males, 61.34% were early neonates,77% babies were of primi  mothers,76% of babies were outborn . 62.12% of babies were born by vaginal route. HIE was most common (88%) cause of seizure. Out of the all seizure types, subtle seizure was most common (87.67%), followed by clonic seizure (35.67%). Various maternal risk factors were present in 81.81 % of cases. Most common risk factor was anemia (50.57%).18.93% of cases were born with  history of obstructed labor/prolonged labor. Overall mortality was 8%.Conclusions: Neonatal seizures are important causes of morbidity and mortality in newborns. Prevention of HIE and maternal risk factors along with early use of an effective drug with minimum side effects are the ways to overcome this problem.

2017 ◽  
Vol 9 (5) ◽  
pp. 50 ◽  
Author(s):  
Rohini Govindasamy ◽  
Manikandan Dhanasekaran ◽  
SheejaS Varghese ◽  
VR Balaji ◽  
B Karthikeyan ◽  
...  

2021 ◽  
pp. 19-20
Author(s):  
C. Hemachithra ◽  
N. Meena

Cerebral palsy (CP) is the most common congenital neurological disorder. The etiological and the risk factors are many and an awareness of the interplay of multiple factors in the causation is crucial. The aim of the study is to investigate the clinical prole and risk factors of CP children in and around Chidambaram. A retrospective cross sectional study was conducted in the Division of Physical Medicine and Rehabilitation, Rajah Muthiah Medical College and Hospital, Chidambaram. Seventy clinically diagnosed CP children were enrolled and clinical prole and history were retrieved from the case sheets and the parents of CP children. The result shows that out of 70 CP children 53% of males and 47% of females were found. The anthropometric measurements like height and weight of the CP children were found lower than the normal. Among 70 children spastic type of CP was the most common, Athetoid type (5.7%) and ataxic type (5.7%) are the least common type. This study concluded that neonatal care services in Chidambaram should be reviewed to get more attention which helps to promote early intervention and rehabilitation of CP children.


2021 ◽  
Vol 8 (7) ◽  
pp. 1168
Author(s):  
Gurunathan Gopal

Background: Babies with a birth weight of less than 2500 grams, irrespective of the period of their gestation are termed as low birth weight (LBW) babies. Despite consistent efforts to improve the quality of maternal and child health, more than twenty million LBW babies are born every year throughout the world. The present study was to explore the effects of various maternal risk factors associated with low birth-weight of institutionally delivered newborns. Across the world, neonatal mortality is 20 times more likely for LBW babies compared to normal birth weight (NBW) babies (>2.5 kg).Methods: A cross sectional study was conducted in neonatal intensive care unit (NICU) of ACS Medical College and Hospital, Chennai from December 2019 to October 2020. Altogether 350 babies were taken who were delivered at ACS hospital.Results: The number of times of ANC attendance was also significantly associated with LBW, odds ratio (OR)=1.296, and p=0.001. The number of meals was not associated with LBW OR=0.946, and p=0.831. The gestational age assessed as completed weeks of pregnancy was significantly associated with LBW OR=3.302; p=0.00001.Conclusions: This study suggests that there are several factors interplaying which lead to LBW babies. Socio-demographic factors (maternal age and gestational age) and antenatal care are more important.


2019 ◽  
Vol 26 (12) ◽  
pp. 2044-2047
Author(s):  
Faraz Ahmed ◽  
Mohsin Ali ◽  
Hussan Ali Sarwar ◽  
Miqdad Haider ◽  
Muhammad Bilal Safdar ◽  
...  

One of the major and important but preventable causes of neonatal morbidity and mortality is Neonatal sepsis. Objectives: To determine the frequency of maternal risk factors in diagnosed cases of early neonatal sepsis. Study Design: Descriptive cross sectional study. Setting: Nursery, Department of Children Hospital and the institute of child health, Lahore. Period: 15-01-2016 to 15-07-2016. Material and Methods: After approval from hospital ethical committee, according to inclusion and exclusion criteria, 250 patients were enrolled in the study from nursery department of children hospital, Lahore. Maternal risk factors i.e. PROM, meconium stained liquor and preterm delivery were recorded along with the demographic information of each case. Results: In our study, out of 250 cases, cases between 1-2 days were 64.8% (n=162) while cases between 3 days of life were 35.2% (n=88), mean+sd was resulted as 2.17+0.69 days. Frequency of maternal risk factors in diagnosed cases of early neonatal sepsis was turned out as 64.8% (n=162) PROM, 29.6% (n=74) meconium stained liquor and preterm delivery was resulted in 21.2% (n=53). Conclusion: The leading maternal risk factor is PROM followed by meconium stained liquor and preterm delivery in diagnosed cases of early neonatal sepsis.


2019 ◽  
Vol 57 (219) ◽  
Author(s):  
Sunil Raja Manandhar ◽  
Rydam Basnet

  Introduction: Perinatal asphyxia is one of the major causes of perinatal and early neonatal mortality in developing countries. The main objective of this study was to observe the prevalence of perinatal asphyxia in babies born at Kathmandu Medical College Teaching Hospital. Methods: This was a descriptive cross-sectional study conducted at Kathmandu Medical College Teaching Hospital over six month period (January to June 2019). All preterm, term and post term babies delivered at Kathmandu Medical College Teaching Hospital were included. Ethical clearance was received from Institutional Review Committee of Kathmandu Medical College (Ref.:2812201808). Convenient sampling method was applied. Data analysis was done in Statistical Package for Social Sciences (SPSS 18), point estimate at 95% Confidence Interval was calculated along with frequency and proportion for binary data. Results: A total of 1284 babies delivered over six months period were enrolled in this study and 47 (3.66 %) babies were asphyxiated, at 95% Confidence Interval (2.64%-4.68%). The mean birth weight of asphyxiated babies was 2759.75±65 grams and gestational age was 37.57±2 weeks. Among asphyxiated babies, 15 (32%) babies were normal, 15 (32%) babies were in Hypoxic Ischemic Encephalopathy stage I, 14 (30%) were in stage II and 3 (6%) were in stage III. Twenty Three (49%) asphyxiated babies had antenatal risk factors and all 47 babies had intrapartum risk factors leading to asphyxia. Conclusions: Prevalence of perinatal asphyxia was lower compared to that of other similar tertiary care hospitals. Perinatal asphyxia remains a major cause of neonatal morbidity and mortality.


2011 ◽  
Vol 51 (1) ◽  
pp. 52 ◽  
Author(s):  
Melani Rakhmi Mantu ◽  
Lelani Reniarti ◽  
Sjarif Hidajat Effendi

Background Small for gestational age (SGA) neonates often have intrauterine growth restriction due to placental insufficiency and chronic hypoxia. These conditions may cause developmental impairment, psychosocial disabilities, or metabolic dysfunction in later life. Previous studies have shown greater incidence of speech and language disabilities, learning impairment, and neuromotor dysfunction in term SGA infants compared to term appropriate for gestational age (AGA) infants.Objective To compare hearing loss in SGA and AGA neonates using otoocoustic emission (OAE) tests and to study correlations between maternal risk factors and hearing loss in SGA neonates.Methods A cross-sectional study was performed in St. Borromeus Hospital, Limijati Hospital, and Melinda Hospital in Bandung from February to May 2010. Study subjects consisted of full-term neonates born in these three hospitals. A retrospective medical record review was performed for this study. Statistical analysis was done by multivariable logistic-regression.Results There was a total of 4279 subjects in our study, including 100 SGA neonates and 4179 AGA neonates. We observed a greater percentage of OAE 'refer' (indicating abnormal OAE) results in the SGA group compared to the AGA group (P<0.001, Z=13.247). For suhjects with OAE 'refer' results, we also analyzed the correlation to the following maternal risk factors: smoking, hypertension, diabetes mellitus and asthma. We also found significant differences between  those with and without each of the four maternal risk factors studied (P< 0.001). By using multivariant analysis to compare SGA and AGA neonates, we found the odds ratio (OR) to he 4.34 (95% CI 2.52 to 7.49, P=0.001), meaning the SGA group had a 4.34 times higher risk of hearing loss than the AGA group.Conclusion SGA neonates had a higher risk of hearing loss than AGA neonates. In addition, maternal smoking, hypertension, diabetes mellitus and asthma significantly correlated to hearing loss in all newborns. [


2020 ◽  
Author(s):  
Bereket Yismaw Fantahun ◽  
Ikram Nurussen

Abstract Background Hypoglycaemia is a common metabolic abnormality seen in neonates that can cause preventable death. Its overall incidence has been estimated to be 1 to 5 per 1,000 live births, with higher incidence in at-risk populations. There is limited data regarding its prevalence and risk factors in developing countries like Ethiopia. Therefore, this study was aimed to determine the prevalence and risk factors of neonatal hypoglycaemia in neonatal intensive care unit (NICU) at Saint Paul’s Hospital Millennium Medical College (SPHMMC), Addis Ababa, Ethiopia. Methodology A cross sectional study was conducted from June 17 to August 3, 2018 at SPHMMC, NICU. Neonates whose age was less than 48hrs and admitted to NICU were enrolled. Sociodemographic, maternal and neonatal factors were collected using structured questionnaire. Blood glucose was measured using glucometer with a test strip. Random blood glucose level < 47mg/dl was taken as a cut-off point to define hypoglycaemia. The data was entered and analysed using SPSS version 20. Results Neonatal hypoglycaemia was detected in 25% (49/196) of the neonates. Birth weight, duration of labor, maternal age, time of feeding initiation, hypothermia and respiratory distress syndrome were associated with hypoglycaemia. From these factors, maternal age, birth weight and hypothermia were found to be independent predictors of the outcome. Conclusion Hypoglycaemia was prevalent in neonates admitted to the NICU of SPHMMC and was associated with low birth weight and hypothermia. These findings calls for early detection of hypoglycaemia, prevention of hypothermia and early initiation of feeding to prevent neonatal morbidity and mortality.


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