scholarly journals Study of serum lipid profile and serum lipo-protein (a) in type II diabetes mellitus patients compared to non-diabetics

2021 ◽  
Vol 8 (9) ◽  
pp. 1323
Author(s):  
J. Prathyusha Rao ◽  
Abhinav Thota
Keyword(s):  
Diabetes Mellitus ◽  
Lipid Profile ◽  
Blood Sugar ◽  
Serum Lipid ◽  
Protein A ◽  
Serum Lipid Profile ◽  
Hypoglycemic Agents ◽  
Type Ii ◽  
Lipoprotein A ◽  
Type Ii Diabetics

Background: This study helps us in evaluating present Indian scenario of lipid and diabetic portfolio, and advices about how aggressive treatment should be for immediate control of blood sugars and lipids are to minimize the cardiovascular risks. The objective of this study was to evaluate the serum lipid profile and lipo-protein (a) levels in comparison to patients with type II diabetics with non-diabetics.Methods:It was a hospital-based case control study conducted on patients presenting with signs and symptoms of diabetes mellitus and confirmed on doing appropriate investigation. 200 patients of which 100 were non-diabetic (control) and 100 type II diabetic patients, of which fifty were type II diabetics were on oral hypoglycemic agents (OHA) and 50 were on insulin only, were selected after matching for age and sex. Lipid profile, serum lipoprotein (a), ECG, 2D echo was studied in these patients.Results: The males were more (74%) than females (26%) among the cases. Fasting blood sugar, post prandial blood sugar and HbA1c were significantly more in cases. Triglycerides, LDL, VLDL and lipoprotein (a) were significantly more in cases. ST shift (mm) and T wave inversions were significantly more in cases compared to controls (p<0.05). Mean ejection fraction was significantly reduced in cases compared to controls. FBS and PPBS were not significantly different in two groups of OHA and insulin but HbA1c was significantly better controlled in insulin group than OHA group.Conclusions:Lipid profile and lipoprotein (a) as well as ECG and 2D echo parameters were significantly worse in diabetes patients. Hence appropriate management is important to prevent risk of complications.

Evaluation of Serum Lipid Profile in Type II Diabetes Patients at Mirpur Khas, Sindh, Pakistan

2021 ◽  
Vol 15 (12) ◽  
pp. 3156-3158
Author(s):  
Pir A. Hayee ◽  
Khalil A. Memon ◽  
Atta Ullah ◽  
M. Akber Hassan ◽  
Shafaq Ansari ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Lipid Profile ◽  
Total Cholesterol ◽  
Rural Areas ◽  
Serum Lipid ◽  
Serum Lipid Profile ◽  
Diabetic Patients ◽  
Type Ii ◽  
College Hospital ◽  
Diabetes Patients

Aim: To assess the serum cholesterol levels of the diabetes patients in the rural areas of the Sindh. Study design: Prospective observational study Place and duration of study: Department of Medicine, Muhammad Medical College Hospital, Mirpurkhas Sindh, Pakistan from 1st January 2020 to 31st December 2020. Methodology: Five hundred and seventeen diabetic type II patients were enrolled in the study after the written informed consent. The serum lipid profile was assessed and analyzed the relation with glycemic values and their treatment. The prescription was also assessed and data were transferred in to data analysis sheet. Results: There were 368 (71.18%) males and 149 (28.82%) females. Moreover 223(43.13%) patients were aged from 51 to 60 years. Patients had 3 to 6 years of diabetic history (51.26%). Patients had glycemic value 151-200mg/dL (33.27%). One hundred and eighty nine patients had total cholesterol value 201-250 mg/dL. One hundred and seventy six patients were prescribed from Sulphonylurea with 34.04%, 205 patients were prescribed lovastatin (39.65%), 97 patients were prescribed rosuvastatin Conclusion: The changes in the lipid profile levels of diabetic patients might occur at different ages along with the morbid condition such as diabetes mellitus and condition can be more complicated if not managed properly. The disruption in the serum lipid profile, total cholesterol, triglycerides, LDL, HDL and obesity cannot be ignored the condition is worse in developing countries like Pakistan. Keywords: Lipid, Diabetes Mellitus, Mirpurkhas, Sindh, Pakistan

scholarly journals Effect of Helicobacter pylori Infection on Serum Lipid Profile

2018 ◽  
Vol 2018 ◽  
pp. 1-5 ◽  
Author(s):  
Mohamadreza Haeri ◽  
Mahmoud Parham ◽  
Neda Habibi ◽  
Jamshid Vafaeimanesh
Keyword(s):  
Helicobacter Pylori ◽  
Lipid Profile ◽  
Blood Sugar ◽  
Serum Lipid ◽  
Density Lipoprotein ◽  
Population Data ◽  
Serum Lipid Profile ◽  
Significant Difference ◽  
H Pylori ◽  
The Relationship

Background. Some studies suggest a significant relationship between Helicobacter pylori infection and atherogenesis; but the mechanism of the relationship is almost unknown. The current study aimed at evaluating the relationship between H. pylori infection and serum lipid profile. Patients and Methods. The current study was conducted on 2573 patients, from 2008 to 2015. The serum anti-Helicobacter pylori antibody titer and serum lipid profile were assessed in the study population; data were statistically analyzed by SPSS version 16. P values < 0.05 were considered significant. Results. In the current study, 66.5% of the cases were serologically positive for H. pylori. Among male cases, the level of low density lipoprotein (LDL) was higher in patients with H. pylori infection, compared with that of the ones without the infection (P=0.03); although level of triglyceride (TG) was higher and the level of high density lipoprotein (HDL) was lower in the cases with H. pylori infection; there was no statistically significant difference between the cases with and without H. pylori infection regarding the level of HDL and TG. Among female cases, the level of TG was significantly lower in patients with H. pylori infection, compared with that of the ones without the infection (P=0.001); but there was no significant difference between the cases with and without H. pylori infection regarding the level of LDL and HDL. The mean fasting blood sugar (FBS) in the cases with H. pylori infection was significantly higher than that of the ones without the infection (P=0.04). Conclusion. According to the results of the current study, the levels of LDL and FBS were high among the male cases with H. pylori infection. However, in females with H. pylori infection the level of TG was low; hence, it seems that the atherogenicity of H. pylori affected the level of blood sugar more.

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