scholarly journals Full childhood immunization coverage and incidence of vaccine preventable disease in Nigeria: a regression analysis

Author(s):  
Obinna Orjingene ◽  
Ojo Olumuyiwa ◽  
Clara Oguji ◽  
Franco Apiyanteide ◽  
Jude Inegbeboh ◽  
...  

Background: Childhood immunization contributes significantly in the reduction of cases of vaccine preventable diseases in children. DHIS2 data showed that only 60.59% of children under one were fully immunized in 2020. This implies that 39.41% did not receive all recommended vaccinations therefore at risk of contracting vaccine preventable diseases. This study therefore examined the effect of full immunization coverage on incidence of vaccine preventable diseases.Methods: Full childhood immunization coverage and incidence of vaccine preventable disease was examined using simple linear regression model at 5% level of significance and 95% confidence interval. Measles new case for children under five was the dependent variable while children under one fully immunized was the independent variable. Data was retrieved from DHIS2 for the period 2017-2020.Results: The study showed a negative relationship between full immunization coverage and incidence of under-five measles new cases. The study found that any unit increase in full immunization coverage would lead to decrease in measles cases by 6%.Conclusions: Full immunization coverage is still low (below WHO target of 80%) despite effort by government and partners. This implies that a lot of children are at risk of contracting vaccine preventable diseases. In order to avert this risk, health authorities and partners should devise appropriate means of educating the populace on the importance of childhood immunization.

Author(s):  
K. K. Lamiya ◽  
Jesha Mohammedali Mundodan ◽  
Sheela P. Haveri

Background: Many parents have poor understanding of vaccine preventable diseases (VPD) and many believe in false propagations about the contents, side effects and effectiveness of vaccines. Lack of good knowledge and positive attitude about childhood immunization was believed to be the root cause for resurgence of VPDs. Aim of the study was to assess the knowledge, attitude and practice regarding childhood immunization among mothers of under five children.Methods: A cross sectional study was done among mothers with at least one child in the under-five age group residing in the rural field practice area of a teaching institution. Assuming 61% mothers have good knowledge (Mangalore study) the sample size was calculated to be 235 with 20% error and 1.5 design effect. Data was collected with the help of pretested semi structured questionnaire by interviewing 15 eligible mothers from each of 16 wards. Descriptive analysis was done.Results: The average age of the participants was 27.30±5.42 years with many of them educated up to 10th grade (40.3%) and most being housewife (74.5%). Knowledge of mothers regarding the diseases that can be prevented by immunization was fairly good. But the knowledge regarding individual vaccines, their dosages and schedule were found to be low. Majority of mothers had good attitude about immunization. Immunization coverage of the locality was relatively good (87.7%). Significant relation was established between attitude and practice. Sick at the time of vaccination was the most common cause of being partially immunised (68.96%).Conclusions: Intensify the awareness classes for mothers and religious leaders on immunisation.


2021 ◽  
Vol 12 ◽  
pp. 215013272110140
Author(s):  
Oluchi Elekwachi ◽  
La’Marcus T. Wingate ◽  
Veronica Clarke Tasker ◽  
Lorraine Aboagye ◽  
Tadesse Dubale ◽  
...  

Vaccine preventable diseases are responsible for a substantial degree of morbidity in the United States as over 18 million annual cases of vaccine preventable disease occur in the U.S. annually. The morbidity due to vaccine preventable disease is disproportionately borne by adults as over 99% of the deaths due to vaccine preventable diseases occur within adults, and national data indicates that there racial disparities in the receipt of vaccines intended for elderly adults. A literature review was conducted by using the PubMed database to identify research articles that contained information on the vaccination rates among minority populations for selected vaccines intended for use in elderly populations including those for herpes zoster, tetanus, diphtheria, pertussis, hepatitis A, and hepatitis B. A total of 22 articles were identified, 8 of which focused on tetanus related vaccines, 2 of which focused on hepatitis related vaccines, and 12 of which focused on herpes zoster. The findings indicate that magnitude of the disparity for the receipt of tetanus and herpes related vaccines is not decreasing over time. Elderly patients having a low awareness of vaccines and suboptimal knowledge for when or if they should receive specific vaccines remains a key contributor to suboptimal vaccination rates. There is an urgent need for more intervention-based studies to enhance the uptake of vaccines within elderly populations, particularly among ethnic minorities where culturally sensitive and tailored messages may be of use.


2013 ◽  
Vol 46 (2) ◽  
pp. 225-239 ◽  
Author(s):  
OYELOLA A. ADEGBOYE ◽  
DANELLE KOTZE ◽  
OLASUNKANMI A. ADEGBOYE

SummaryAs a leading indicator of child health, under-five mortality was incorporated in the United Nations Millennium Development Goals with the aim of reducing the rate by two-thirds between 1990 and 2015. Under-five mortality in Nigeria is alarmingly high, and many of the diseases that result in mortality are vaccine preventable. This study evaluates the uptake of childhood immunization in Nigeria from 1990 to 2008. A multi-year trend analysis was carried out using Alternating Logistic Regression on 46,130 children nested within 17,380 mothers in 1938 communities from the Nigerian Demographic and Health Surveys from 1990 to 2008. The findings reveal that mother-level and community-level variability are significantly associated with immunization uptake in Nigeria. The model also indicates that children delivered at private hospitals have a higher chance of being immunized than children who are delivered at home. Children from the poorest families (who are more likely to be delivered at home) have a lower chance of being immunized than those from the richest families (OR=0.712; 95% CI, 0.641–0.792). Similarly, the chance of children with a mother with no education being immunized is decreased by 17% compared with children whose mother has at least a primary education. In the same way, children of mothers who are gainfully employed and those of older mothers have statistically significantly higher odds of being immunized. Children of households with a female head are less likely to be immunized than those from male-headed households. The statistical significance of the community–survey year interaction term suggests an increase in the odds of a child being immunized over the years and spread over communities. Evidence-based policy should lay more emphasis on mother- and community-level risk factors in order to increase immunization coverage among Nigerian children.


2021 ◽  
Author(s):  
Catherine Ji ◽  
Pierre-Philippe Piche-Renaud ◽  
Jemisha Apajee ◽  
Ellen Stephenson ◽  
Milena Forte ◽  
...  

Background: The COVID-19 pandemic has caused a disruption in childhood immunization coverage around the world. This study aimed to determine the change in immunization coverage for children under 2 years old in Ontario, Canada, comparing time periods pre-pandemic to during the pandemic. Methods: We conducted an observational retrospective open cohort study, using primary care electronic medical record data from the University of Toronto Practice-Based Research Network (UTOPIAN) database, from January 2019 to December 2020. Children under 2 years old who had at least 2 visits recorded in UTOPIAN were included. We measured up-to-date (UTD) immunization coverage rates, overall and by type of vaccine (DTaP-IPV-Hib, Pneu-C-13, Rot, Men-C-C, MMR, Var), and on-time immunization coverage rates by age milestone (2, 4, 6, 12, 15 and 18 months). We compared average coverage rates over 3 periods of time: January 2019-March 2020 (T1); March-July 2020 (T2); and August-December 2020 (T3). Results: 12,313 children were included. Overall UTD coverage for all children was 71.0% in T1, dropped by 5.7% (95% CI: -6.2, -5.1) in T2, slightly increased in T3 but remained lower than in T1. MMR vaccine UTD coverage slightly decreased in T2 and T3 by approximately 2%. The largest decreases were seen at ages 15-month and 18-month old, with drops in on-time coverage of 14.7% (95% CI: -18.7, -10.6) and 16.4% (95% CI: -20.0, -12.8) respectively during T2. When stratified by sociodemographic characteristics, no specific subgroup of children was found to have been differentially impacted by the pandemic. Conclusion: Childhood immunization coverage rates for children under 2 years in Ontario decreased significantly during the early period of the COVID-19 pandemic and only partially recovered during the rest of 2020. Public health and educational interventions for providers and parents are needed to ensure adequate catch-up of delayed/missed immunizations to prevent potential outbreaks of vaccine-preventable diseases.


2020 ◽  
Vol 30 (Supplement_5) ◽  
Author(s):  
M Biswas

Abstract India has been significantly progressed in full immunization care over the last few decades. Existing literature has not been unaddressed the potential spatial variations in relationships between full immunization coverage and its influence on socio-economic factors. The study aims to explore place-specific spatial dependencies and heterogeneities in the relationships of various factors on the district-level full immunization coverage in India. The study used a geocoded database for 640 districts of India, drawn from the 4th wave of the National Family Health Survey (NFHS) in 2015-16. Univariate Moran's I and LISA maps were used to confirm the spatial autocorrelation and geographical hotspots of the district-level full immunization coverage. Multivariate Ordinary Least Squares (OLS) and Geographically Weighted Regression (GWR) models were employed to examine spatial relationships and decrypt location-based district-level analysis. The prevalence of full immunization care was 62 percent as per the national figure. The GWR results revealed that the relationships between the outcome and set of cofactors were significantly place-specific and spatially clustering in terms of their respective magnitude, direction, and differences in due to local characteristics across India. In terms of model performance and prediction accuracy, the GWR model was performing better over OLS estimates through comparisons of R2 and Akaike Information Criterion (AICC) in both models. Furthermore, the GWR model also improves the reliabilities of the relationships by reducing spatial autocorrelations. The findings suggest that the local GWR model has the potential to explain complexities in place-specific variations that could be ignored by OLS on the local causes of immunization coverage. Thus, appropriate intervention should be devised to safeguard child from vaccine-preventable diseases reduce the geographical heterogeneity of full immunization coverage across India. Key messages This study aims to explore place-specific spatial dependencies and heterogeneities in the relationships of various factors on the district-level full immunization coverage in India. To explain local complexities in place-specific variations that could be ignored by the traditional model on the local causes of full immunization coverage across India.


2021 ◽  
Vol 9 (1) ◽  
pp. 176-196
Author(s):  
Vishesh Kumar

Background: Vaccination against childhood communicable diseases through Expanded Program on Immunization is one of the most cost-effective public health interventions. Additional 1.5 million child deaths can be prevented if global vaccination coverage is improved. Mewat district has one of India’s lowest immunization rates despite a long-standing Universal Immunization Program and continues to sustain a high prevalence of vaccine-preventable diseases. This study investigates determinants of immunization status among children aged 0-23 months. Methods: A community-based cross-sectional study was conducted from December 2019 to June 2020, among 800 children aged 0-23months, randomly selected in one rural and one urban ward each from all 4 blocks of Mewat. Socio-demographic conditions and vaccine-related data were collected using a semi-structured questionnaire. Immunization was assessed by vaccination card and by mother’s recall where the card was unavailable. Results:Mewat has increased full immunization coverage from 13.1% in 2015-16 to 59.4%. Immunization card was available with 68.5% (292/426) beneficiaries. Dropout rates for Pentavalent1 to Pentavalent3 was 27.5% and 54% for Bacillus Calmette-Guerin to measles. After adjusting for the state of residence, religion, gender, paternal education, health professional presence during birth, place of vaccination and knowledge of mother on due dose were significantly associated with full immunization. Awareness gap and fear of side effects for vaccines were main reasons of vaccine hesitancy. Conclusion: Full immunization coverage in the district is sub optimal and behind the desired coverage goal, mainly due to vaccine hesitancy. Enhancing community knowledge about the benefits of vaccination is recommended.


Medicina ◽  
2019 ◽  
Vol 55 (8) ◽  
pp. 480 ◽  
Author(s):  
Abdur Razzaque Sarker ◽  
Raisul Akram ◽  
Nausad Ali ◽  
Zahedul Islam Chowdhury ◽  
Marufa Sultana

Background and Objectives: In line with the global success of immunization, Senegal achieved impressive progress in childhood immunization program. However, immunization coverage is often below the national and international targets and even not equally distributed across the country. The objective of this study is to estimate the full immunization coverage across the geographic regions and identify the potential factors of full immunization coverage among the Senegalese children. Materials and Methods: Nationally representative dataset extracted from the latest Continuous Senegal Demographic and Health Survey 2017 was used for this analysis. Descriptive statistics such as the frequency with percentage and multivariable logistic regression models were constructed and results were presented in terms of adjusted odds ratio (AOR) with a 95% confidence interval (CI). Results: Overall, 70.96% of Senegalese children aged between 12 to 36 months were fully immunized and the coverage was higher in urban areas (76.51%), west ecological zone (80.0%), and among serer ethnic groups (77.24%). Full immunization coverage rate was almost the same between male and female children, and slightly higher among the children who were born at any health care facility (74.01%). Children who lived in the western zone of Senegal were 1.66 times (CI: 1.25–2.21; p = 0.001) and the children of Serer ethnic groups were 1.43 times (CI: 1.09–1.88; p = 0.011) more likely to be fully immunized than the children living in the southern zone and from the Poular ethnic group. In addition, children who were born at health facilities were more likely to be fully immunized than those who were born at home (AOR = 1.47; CI: 1.20–1.80; p < 0.001), and mothers with recommended antenatal care (ANC) (4 and more) visits during pregnancy were more likely to have their children fully immunized than those mother with no ANC visits (AOR: 2.06 CI: 1.19–3.57; p = 0.010). Conclusions: Immunization coverage was found suboptimal by type of vaccines and across ethnic groups and regions of Senegal. Immunization program should be designed targeting low performing areas and emphasize on promoting equal access to education, decision-making, encouraging institutional deliveries, and scaling up the use of antenatal and postnatal care which may significantly improve the rate full immunization coverage in Senegal.


Author(s):  
Nancy Vicente-Alcalde ◽  
Jose Tuells ◽  
Cecilia M. Egoavil ◽  
Esther Ruescas-Escolano ◽  
Cesare Altavilla ◽  
...  

The correct immunization of the inmate population minimizes the risk of transmission of vaccine-preventable diseases in prisons. The objective of this study was to evaluate the vaccine coverage of long-term prisoners in the Spanish penitentiary system through a retrospective longitudinal study. One-thousand and five prisoners were selected, who were imprisoned from 2008 and 2018 in three Spanish prisons. Their degree of immunization was evaluated as related to hepatitis A (HAV), hepatitis B (HBV), tetanus, diphtheria, pneumococcus and seasonal flu. The state of vaccination of the prisoners with a serological diagnosis of HBV, hepatitis C (HCV) and human immunodeficiency virus (HIV) was also evaluated. The vaccination coverage obtained for hepatitis B was 52.3%, and for tetanus–diphtheria, it was 71.9%. However, for hepatitis A and pneumococcus infection, it was insignificant (<2% of the prisoners). Vaccination against seasonal flu was lower than 16%. The HCV and HIV-positive inmates were not correctly vaccinated either. The insufficient level of immunization obtained reflects the lack of interest and marginalization of this population by the penitentiary system and the health authorities. The lack of reliable records is combined with the lack of planned strategies that promote stable and well-defined programs of active vaccination.


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