scholarly journals Impact of active smoking on nasal functions in patients with allergic rhinitis

Author(s):  
Pratibha Chamarajanagara Bhaskara ◽  
Anita Ross ◽  
Neha Gupta

<p class="abstract"><strong>Background:</strong> Allergic rhinitis is an important health problem in view of its prevalence and its impact on patients’ social life, school performance and work productivity. Smoking is known to affect the asthmatic airway inflammation. The additional effect of smoking in impairment of nasal functions in patients with allergic rhinitis is a subject of interest. The aim and objective of this study was to study the effect of active tobacco smoke on mucociliary clearance and olfactory thresholds in allergic rhinitis.</p><p class="abstract"><strong>Methods:</strong> A descriptive observational pilot study was carried out on 40 patients of allergic rhinitis. Nasal mucociliary clearance was measured by saccharine transit time and olfactory threshold test was measured by butanol threshold test score.  </p><p class="abstract"><strong>Results:</strong> The saccharine transit time was significantly prolonged in smokers as compared to nonsmokers. Amongst the subgroups of allergic rhinitis mucociliary clearance was found to be more prolonged with the severity of allergic rhinitis. Butanol threshold test scores were significantly lower in smokers when compared to non- smokers. Amongst the subgroups of allergic rhinitis olfactory threshold was found to be lower with the severity of allergic rhinitis.</p><p><strong>Conclusions:</strong> In the current study we found that nasal functions were significantly impaired in smokers with allergic rhinitis. This indicates that smoking leads to worsening of symptoms in allergic rhinitis.</p>

2010 ◽  
Vol 3 (2) ◽  
pp. 93-95
Author(s):  
Rupender K Ranga ◽  
Jyoti Yadav ◽  
Jagat Singh

Abstract Allergic rhinitis in children is not an uncommon disease in India. Our objective was to evaluate the effect of allergic rhinitis on nasal mucociliary clearance. The nasal mucociliary clearance time (NMC) was studied using Andersen's saccharin method in fifty controls and fifty age and sex matched patients of allergic rhinitis. The nasal mucociliary clearance time in healthy controls was found to be 5.11 ± 1.51 minutes. A significant impairment (p < 0.01) in nasal mucociliary clearance time of 12.46 ± 3.74 minutes was observed in children suffering with allergic rhinitis, signifying that allergic rhinitis may predispose to sinusitis and pulmonary diseases.


2018 ◽  
Vol 31 (5) ◽  
pp. 917-922 ◽  
Author(s):  
Sevil Ceyhan Doğan ◽  
Ahmet Karadağ ◽  
Kasım Durmuş ◽  
Özlem Şahin ◽  
Emine Elif Altuntaş

2020 ◽  
Vol 49 (11) ◽  
pp. 885-896
Author(s):  
Xuandao Liu ◽  
De Yun Wang ◽  
Tze Choong Charn ◽  
Leslie Timothy Koh ◽  
Neville WY Teo ◽  
...  

Allergic rhinitis (AR) is prevalent in Singapore, with a significant disease burden. Afflicting up to 13% of the population, AR impairs quality of life, leads to reduced work productivity and is an independent risk factor for asthma. In the last 2 decades, local studies have identified patient and physician behaviours leading to suboptimal control of the disease. Yet, there is an overall lack of attention to address this important health issue. Allergic Rhinitis and its Impact on Asthma (ARIA) is a European organisation aimed at implementing evidence-based management for AR worldwide. Recent focus in Europe has been directed towards empowering patients for self-management, exploring the complementary role of mobile health, and establishing healthcare system-based integrated care pathways. Consolidation of these ongoing efforts has led to the release of the 2019 ARIA care pathways. This review summarises the ARIA update with particular emphasis on the current status of adult AR in Singapore. In addition, we identify unmet needs and future opportunities for research and clinical care of AR in the local context. Keywords: Allergen immunotherapy, Allergic Rhinitis and its Impact on Asthma, clinical guideline


2021 ◽  
pp. 000348942110254
Author(s):  
Yavuz Atar ◽  
Semih Karaketir ◽  
Imran Aydogdu ◽  
Hüseyin Sari ◽  
Hasan Sami Bircan ◽  
...  

Objective: We aim to demonstrate the effect of an isotonic seawater spray containing chamomile liquid extract on symptoms and nasal mucociliary clearance in patients with allergic rhinitis by comparing it with other isotonic seawater nasal washing solutions. Methods: The study included 123 patients. Based on Allergic Rhinitis and its Impact on Asthma guidelines, mometasone furoate intranasal spray treatment was started for all patients in the group diagnosed with allergic rhinitis. In addition to this treatment, isotonic seawater spray with chamomile liquid extract was added to Group A, isotonic seawater spray to Group B, and isotonic seawater nasal irrigation to Group C. The fourth group (Group D) was given only nasal steroid spray without nasal washing treatment. Before and after treatment in all patients, the Sino-Nasal Outcome Test-22 was performed, and nasal mucociliary clearance times were measured by the saccharin test. Results: The differences in duration of nasal mucociliary clearance and Sino-Nasal Outcome Test-22 values were taken before and after treatment. In Group A, B, C, and D the Sino-Nasal Outcome Test-22 differences were statistically significant ( P ≤.001; P ≤ .001; P ≤ .001, and P = .048, respectively). Only Group A and Group B experienced a significant difference in nasal mucociliary clearance times ( P ≤ .001; P = .010, respectively). When the Sino-nasal Outcome Test-22 score and nasal mucociliary clearance time differences before and after treatment were compared between all groups, the Sino-Nasal Outcome Test-22 score difference was higher in Group A than in Groups B, C, and D, the differences were found as statistically significant ( P = .010; P = .003; P ≤ .001, respectively). The nasal mucociliary clearance time difference was higher in Group A than in Groups C and D, the differences were found as statistically significant ( P = .010; P = .001, respectively). Conclusion: Isotonic seawater spray containing chamomile liquid extract is seen as a good alternative treatment option for allergic rhinitis patients.


2019 ◽  
Vol 179 (4) ◽  
pp. 297-303 ◽  
Author(s):  
Marek Mikolajczyk ◽  
Krystyna Janukowicz ◽  
Ewa Majewska ◽  
Zbigniew Baj

Author(s):  
Vimal Nambiar ◽  
Sheetal Rai ◽  
Gangadhar Somayaji K. S.

<p class="abstract"><strong>Background:</strong> Allergic diseases in India have been on an uprising trend. 3.5% of the population in INDIA is suffering from Allergic Rhinitis. This study aims to compare the effectiveness of two commonly used intranasal steroids- Fluticasone Furoate (FF) and Fluticasone Propionate (FP) using the nasal mucociliary clearance time (NMCT).</p><p class="abstract"><strong>Methods:</strong> We conducted a prospective study on 70 patients. 35 each on FF and FP. Pretreatment and Post treatment Nasal was assessed by Saccharin Test. Patients were then put on either FF or FP for a period of one month.  </p><p><strong>Results: </strong>Average improvement of NMCT post treatment with steroids sprays is 2-3 minutes.(Average Pretreatment time is 17.92 and Average Post treatment time 15.55 minutes).</p><strong>Conclusion: </strong>Both drugs are equally efficacious and well tolerated by the patients. Compliance of Fluticasone Furoate was better because of its once daily dosage. Disadvantages of FP are its twice daily dosage and after taste.


2016 ◽  
Vol 9 (2) ◽  
pp. 74-76 ◽  
Author(s):  
Vinish Kumar Agarwal ◽  
Mamta Goyal ◽  
Sampan S Bist

ABSTRACT Introduction Allergic rhinitis (AR) is a global health problem that significantly alters patients’ social life and affects learning at school and work productivity. Materials and methods A total of 150 patients suggestive of a history of AR were included in this study. The patients underwent a thorough history, clinical examination, diagnostic nasal endoscopic evaluation, and radiological imaging. Results Out of 150 patients, 65% were male, whereas 35% were female ranging from age 14 to 70 years; 30% of both male and female were between 21 and 25 years; and 85% belonged to urban area, whereas 15% were rural inhabitants. The most significant complaints of patients were mainly paroxysmal sneezing, nasal obstruction, and watery nasal discharge. In the present study, 21% of patients had first-degree relatives with a complaint of AR; 72% of male patients and 75% of female patients had swollen turbinate; 59% of male patients and 62% of female patients had pale edematous nasal mucosa; 68% of male patients and 56% of female patients had granular pharyngitis; and 25% of male patients and 40% of female patients had complications of AR. Conclusion Allergic rhinitis is a disease of youth that affects mostly people in the age group of 21 to 25 years, and it is paroxysmal sneezing that concerns most of the patients and brings them to hospital. About 60% of the patients have a history of contact with the AR patients. Clinical significance Allergic rhinitis involves nearly 600 million people all over the world. Our study suggests three cardinal signs of AR, viz., swollen turbinate, pale and edematous nasal mucosa, and granular pharyngitis. This study also signifies female preponderance for complications of AR. How to cite this article Agarwal VK, Goyal M, Bist SS. Study of Predisposing Factor, Clinical Profile, and Complications of Allergic Rhinitis. Clin Rhinol An Int J 2016;9(2):74-76.


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