scholarly journals A clinico-epidemiological study of polymorphic light eruption in a tertiary care centre in Salem: a region of South India

Author(s):  
Eby Chacko ◽  
Seethalakshmi Ganga Vellaisamy ◽  
Kannan Gopalan ◽  
Govindarajan Nanjappachetty

<p><strong> </strong><strong>Introduction: </strong>Polymorphic light eruption (PMLE) is an acquired photodermatosis characterized by a polymorphic eruption ranging from papulovesicular lesions to large plaques. The prevalence of PMLE varies from 5% to 15% in various studies across the world and<strong> </strong>in India it is 0.56%.</p><p><strong>Objective: </strong>The present study was conducted to study the clinical pattern and to assess the epidemiological aspects of polymorphic light eruption.</p><p><strong>Material and Method: </strong>A cross sectional prospective study was conducted in Dermatology OPD between April 2015 and June 2016. A total of 100 patients with symptoms and signs of PMLE were included in the study. Data were coded and analyzed.</p><p><strong>Results:</strong> Majority of the cases in our study were in the age group of 21 - 30 years (36%). It was more common in females (82%) when compared with males (18%). Occupation of most of the patients (29%) was farmers in our study population. Positive family history of PMLE was seen in 11% of the study population. The commonest form was the papular type (46%) and the second most common type was plaque type (17%). Regarding the distribution of lesions, about  51%  of  our study subjects had polymorphic lesions confined to only one area of their body mostly forearm (25%) followed by face (12%).</p><p><strong>Conclusion:</strong> The prevalence of PMLE was 1.34% in our study population. Pruritus was the presenting complaint in most of the cases and the rash was mainly seen in areas exposed to sunlight.</p>

2021 ◽  
pp. 10-11
Author(s):  
Akhilesh Behra

BACKGROUND- Psoriasis is chronic common papulosquamous disorder. Its aetiology included various environmental and genetic factors. In genetics, HLA-Cw6 is most commonly associated with psoriasis. Childhood psoriasis is also common in worldwide population. However, very few studies done on epidemiological data and HLA-Cw6 analysis in childhood psoriasis patients. AIMS AND OBJECTIVE- Clinicoepidemiological study of childhood psoriasis patients and its association with HLA-Cw6 in a tertiary care centre of Eastern India MATERIALAND METHOD- We conducted a cross-sectional study in a tertiary care centre and recruited 20 patients of psoriasis with age group below 18 years after taking proper consent. Clinical history and blood was taken from them and HLA-Cw6 analysis was done by PCR method. Data compilation was done by Microsoft excel using SPSS software. RESULTS- A total of the 20 childhood psoriasis patients, 9 were males and 11 were females. Generalized plaque type psoriasis (N=19) is commonest followed by guttate psoriasis (N=1). None of the patients had arthalgia. Family history was present in only 3 patients. Higher numbers of childhood psoriasis patients (N=14) were positive for HLA-Cw6. Also Higher numbers of females (N=10) were positive for HLA-Cw6. ve patients had nail changes. CONCLUSION- We found HLA-Cw6 is strongly associated with childhood psoriasis and also HLA-Cw6 frequency is higher in female than male childhood psoriasis patients.


2017 ◽  
Vol 2 (1) ◽  
pp. 30-33
Author(s):  
SK Shahinur Hossain ◽  
Md Safiul Islam ◽  
Md Mustafizur Rahman ◽  
Shubhashish Dey ◽  
Khurshid Mahmud

Background: Cough variant asthma is presented with different clinical and demographic characteristics.Objectives: The purpose of the present study was to see the clinico-demographic profiles of cough variant asthma patients.Methodology: This descriptive type of cross-sectional study was carried out in theDepartment of Respiratory Medicine at National Institute of Diseases of the Chest and Hospital (NIDCH), Dhaka, Bangladesh from September 2014 to August 2015 for a period of one year. Patients presented with cough variant asthma attending in NIDCH were selected as study population. Methacholine challenge test was performed to diagnosis of Cough Variant Asthma. Result: A total number of 50 patients were recruited for this study. The mean age±SD was found 19.1±7.6 years. Male was predominant than female with a ratio of 1.4.:1. Among the study population positive family history of asthma was found in 39.0% cases and associated allergic rhinitis was reported in 58.0% cases. Eczema was associated with 16.0% patients;however, only 4% patients had associate conjunctivitis. Conclusion: In conclusion young male is more commonly affected by cough variant asthma of which majority have family history of asthma. Journal of National Institute of Neurosciences Bangladesh, 2016;2(1):30-33


2013 ◽  
Vol 64 (4) ◽  
pp. 489-495 ◽  
Author(s):  
Zalika Klemenc-Ketiš ◽  
Borut Peterlin

Abstract This multicentre, cross-sectional observational study aimed to determine the prevalence of depression among the working population of Slovenia and identify factors correlating with higher prevalence of depression. It was conducted in three occupational medicine practices within major Slovenian primary health care centres. The study population consisted of 1,474 respondents [73.7 % of the invited participants, 889 (60.3 %) men and 585 (39.7 %) women with mean age of (40.5±9.8) years] who visited these practices for their regular check-ups from November 2010 to June 2012 and were asked to fill in a self-developed questionnaire and score depression on the Zung’s self-rating depression scale. According to the rating, 50 (3.4 %) respondents suffered from depression. In the multivariate analysis, depression correlated with the following independent variables: self-perceived exposure to chronic stress, positive family history of depression, and primary school education.


Author(s):  
Suganya Sekar ◽  
Samuel J. Daniel

<p class="abstract"><strong>Background:</strong> Psoriasis is a chronic disorder with the most common manifestation being the plaque-type. Nearly 20% of the plaque type suffer from a disease of moderate to severe intensity with immense effect on the quality of life. Aim was to study the clinical, socio-economic and demographic characteristics of patients with moderate to severe plaque type of psoriasis.</p><p class="abstract"><strong>Methods:</strong> This was an observational study conducted in about fourty patients diagnosed with moderate to severe plaque type of psoriasis based upon the clinical history, morphology of the lesions and assessed using psoriasis area and severity index (PASI), dermatology life quality index (DLQI) scoring and for comorbidities. Data was compiled and analyzed with statistical package for social science (SPSS) Version 20.0.</p><p class="abstract"><strong>Results:</strong> Mean age was 37.43±10.1 years. 22 were males (55%) and 18 were females (45%). The mean duration was 8.93 years and 15% had family history. The mean age of onset was earlier in the females (20.23 years) with a positive family history, as compared to males (25.36 years). About 62.5% had moderate psoriasis and 37.5% had severe psoriasis. At the baseline the PASI score was 31.98±6.08 and DLQI score was 36. About 67.5% had nail changes and 10% had psoriatic arthritis. Almost in half (47.5%) the duration of the disease was 1 to 5 years and scalp (32.5%) the most common initial site of involvement. Various comorbidities were documented, 72% in moderate psoriasis and 73.33% in severe psoriasis with dyslipidemia (67.5%) being commonest.</p><p class="abstract"><strong>Conclusions:</strong> Patients with moderate to severe psoriasis mostly have a low quality of life with multiple significant co-morbidities that increases the risk for morbidity and mortality.  </p>


Author(s):  
Rajesh Hadia ◽  
Idrisi Mohammed Tousif ◽  
Avani Kapadia ◽  
Suchitra Pillai ◽  
Hemraj Singh Rajput ◽  
...  

Background: Acne vulgaris remains one of the commonest diseases to afflict humanity, with over 90% of males and 80% of females affected by the age of 21 years. Objectives: The aim of this study was to assessing the specific risk factors, determine the epidemiology and etiology of Acne Vulgaris. Methodology: It is a cross-sectional observational study conducted for a period of six month in the department of dermatology, Dhiraj General Hospital, Vadodara. Patients who were diagnosed with acne vulgaris and fulfilled the inclusion criteria were enrolled in the study. Data was collected by filling the patient medical record sheet. Result: Total 300 patients were included in the study. Out of which 38.67% males and 61.33% females were found affected by Acne Vulgaris. The mean age group affected were found to be 21.77±4.06 years. When compared their social habits, patients consumed more caffeine (49.67%) than alcohol (24.67%), smoking (15.33%) and tobacco (5.67%). 32.33% patients also had history of seborrheic dermatitis. Using GAGS scale, we found 94% patients suffered from moderate Acne condition while 6% suffered from severe Acne condition. Conclusion: Acne Vulgaris was predominantly found in females in adolescence and in males in adulthood. The severity was found more in males than females. The common site for Acne Vulgaris was found to be face while comedones and papules were the common types of lesions. Stress was found to be one of the major aggravating factors for severity of Acne Vulgaris.


Author(s):  
Ashis Samuel John ◽  
Kamaxi M. Bhate

Background: Inadequate understanding by patients of medical prescription given to them adversely affects treatment compliance; which can result in treatment failure and increase the incidence of adverse effects. The study site is a tertiary care hospital in a metropolitan city and the patients attending here are particularly vulnerable in this regard both due to the heavy patient load in the outpatient department and their low socioeconomic status.Methods: This was a cross sectional study conducted in the pharmacy of K.E.M. Hospital, Mumbai over a period of 1 month. Study population included general outpatient department patients of the hospital. Patients were interviewed using a pre validated questionnaire and their knowledge of the prescription analysed under five key aspects including dose, timing, duration, side effects and purpose of each drug. Data was entered using Microsoft Excel and analyzed using SPSS 22 software.Results: The mean age of the population was 37.6, with a standard deviation of 12.4. A good overall knowledge of the prescription was present only in 12.4% patients. In 52% of patients, the level of knowledge ranged from ‘no knowledge to little knowledge’. Age and literacy had statistically significant associations with overall knowledge of prescription.Conclusions: There is a significant gap in prescription knowledge in the study population. Age and literacy of the patient has an effect on prescription knowledge.


2020 ◽  
Vol 16 (2) ◽  
Author(s):  
Marie Stanley Ambroise ◽  
Marie Jeffrey Ambroise

Objective: ‘Elder Abuse’ is a major issue impacting many households. Although several surveys to understand this growing crime against elders has shown varied prevalence worldwide, not much data exists in the state of Puducherry. The main objectives were to screen for abuse, study the demographic patterns of the abused elderly, to estimate their reporting behaviour and awareness of redress mechanisms. Methods: A cross-sectional analysis on the elderly patients attending the out-patient department of a tertiary care centre in Puducherry for various ailments. A semi-structured questionnaire was used to collect data from 300 patients after their informed consent, and the results were statistically analysed. Results: About one-fifth of the elderly reported abuse, the majority belonged to lower socio-economic strata. Disrespect was the most common form of abuse experienced. While the Police Helpline was reported to be the most known redress mechanism, more than one-third of the study population were not aware of any form of redress mechanisms. Conclusion: The findings highlighted the range and type of abuse experienced. The general perception that the families are the safest place for the elderly in India has been questioned by the findings which emerged from this study. Although the victims were aware of the help and support received through police and other agencies, several obstacles to seeking help and support were identified.


Author(s):  
Jyoti Dattaramji Bhise ◽  
Swati Dattaramji Bhise

Background: Animal bite, one of the common causes of physical injuries in spite of a long standing nature of the dog bite problem and the presence of effective intervention strategies for rabies control, it continues to pose a major public health challenge to program planners. So the present study is conducted to study Profile of animal-bite cases at immuno-prophylaxis clinic, at tertiary care centre.Methods: The present study was an observational cross-sectional study carried out at immune prophylaxis clinic of tertiary care centre, from 1st January 2013 to 31st December, 2013. All the registered cases of animal bite attending immune-prophylaxis clinic, which are ready to participate in the study were included as study population. The method used was systematic random sampling. First case was selected randomly using lottery method and then every fifth case reporting to immune prophylaxis clinic was taken in the study group. Total 3504 cases of animal bite were reported during the study period. 20% of these i.e. 700 cases of animal bite were included in the study.Results: Out of 700 study subjects, highest number of bites occurred in the age group 21-30 years i.e. 155 (22.1%). Maximum study subjects 471 (67.3%) were from urban area and 53% of bites occurred during daytime. Maximum cases were the class-III bite i.e. 600 (85.7%).Conclusions: Maximum number of bites seen among 21-30 years of age group predominantly seen among male study subjects. 49.6% study subjects were bitten by pet animals and 47.6% were bitten by stray animals. Dog was the principle animal responsible for the bite of study subjects. 85.7% of study subjects were of class III bite among them 75% study subjects had reported to hospitals within 24 hours. Severe the degree of exposure, earlier was reporting to the hospital was statistically significant.


2019 ◽  
Vol 6 (11) ◽  
pp. 4080
Author(s):  
Archana Dipa Sangita Kujur ◽  
Nishith M. Paul Ekka ◽  
Satish Chandra

Background: The overuse and volume of antibiotic prescription has been found to correlate to the incidence of bacterial resistance. Clinical audit and education can favourably change antibiotic prescribing patterns among practitioners.Methods: Prospective cross-sectional prevalence survey carried out in inpatient department (IPD) and outpatient department (OPD) of department of Surgery, Rajendra Institute of Medical Sciences, Ranchi. 200 prescriptions from OPD and 200 case sheets from IPD were randomly selected. Data was analyzed as per WHO outpatient prescribing indicators. ICU patients and patients on anti-tubercular treatment, antifungals etc. were excluded from this study. Data were computed and analyzed using MS Excel.Results: In the OPD, the average no of drugs per patient was 3.445 of which 17% were injections. 33% of drugs prescribed were antibiotics. Beta-lactams followed by nitroimidazoles were the most common antibiotic class. In the IPD, an average of 2.26 antibiotics per patients was prescribed. 21% of antibiotics were prescribed by a generic name and 196 patients received antibiotic prophylaxis. β-lactams again were the most commonly prescribed antibiotic class with 42.7% (n=193) of total antibiotics prescriptions, Metronidazole (n=101, 22.37%) was the most prescribed antimicrobial agent.Conclusions: The practice of polypharmacy and high antibiotic prescription rate is a concern in our part of the country. Prescriptions writing in generic name needs to be encouraged. There is an acute need for the development of antibiotics prescribing guidelines in India.


2019 ◽  
Vol 6 (5) ◽  
pp. 1466
Author(s):  
Jimnaz P. A. ◽  
Nishad N. ◽  
Harris P.

Background: There is a shift in age of onset of diabetes to a younger age in the recent years. There are very few data available on diabetes in the youth. Hence the study has been undertaken. Objective of the study is to describe the clinical profile of young diabetics and to estimate burden of selected end organ complications at the time of study.Methods: A hospital based Cross sectional study was conducted at a tertiary care centre among 75 young diabetic patients (aged 15-30 years). After taking informed consent, detailed history clinical examination, biochemical investigations like FBS and 2 hours PPBS, HbA1c, lipid profile, screening for neuropathy, retinopathy and nephropathy were done.Results: The mean age of the study population was 26.35±3.8 years, majority were males (62.7 %), 77.3% have positive family history. Mean BMI was 24.8±4.6 kg/m2, 45.3% were overweight ,20 % were obese. The mean FBS levels was 216.63±73.46 mg/dl, 2 hr PPBS 261.51±80.0 mg/dl and mean HbA1c 8.66±1.34 %. The total cholesterol level was higher in 46.7%, with mean of 198.4±21.0. Mean triglyceride level was 136.99±38.9. Nephropathy was present in 25.3%, retinopathy in 13.3% and neuropathy in 9.3 % of the patients. 30.6% had at least one of the three complications. SBP was associated with neuropathy(p=0.030), DBP with retinopathy(p=0.029) and neuropathy(p=0.007) and high FBS levels with retinopathy(p<0.001) and neuropathy(p<0.001).Conclusion: Microvascular complications in young diabetes is alarmingly high. Regular screening, early detection, adequate control of FBS and BP may improve quality of life.


Sign in / Sign up

Export Citation Format

Share Document