scholarly journals Correlation between haematological profile and body mass index in adults

2021 ◽  
Vol 8 (2) ◽  
pp. 86-89
Author(s):  
Tejashwini V Basarigidad ◽  
Ganashree C P
Keyword(s):  
Type 2 Diabetes ◽  
Body Mass Index ◽  
Leucocyte Count ◽  
Haemoglobin Concentration ◽  
The Body ◽  
Total Leucocyte Count ◽  
Haematological Profile ◽  
Obese Subjects ◽  
Rbc Count

Obesity is defined as excessive accumulation of fat in various tissues in the body which causes ill health in the body. The basic cause of obesity is imbalance between calories intake and calories expenditure There is increased intake of calorie rich foods and reduced physical activity due to urbanization all over the world.Body mass index is simple formula to classify obesity in adults. It is defined as person’s weight in kilograms divided by height in meter squares (m).Obesity and elevated BMI are the major causes for development of chronic diseases like stroke, hypertension, Type 2 diabetes and other cardiovascular disorders.BMI is the modifiable risk factors of type 2 diabetes, hypertension, stroke and cardiovascular diseases. This study was undertaken to assess the relationship between BMI and haematological profile among young Indian population. This study comprises 200 participants comprising 100 males and 100 females aged between 18 to 30 years. The design for this study was cross-sectional survey. Ethical approval was taken from ethical committee of BMCH, Chitradurga. Under aseptic precaution, 10 ml of venous blood sample collected from antecubital vein and then transfererd to EDTA tube. Then haematological parameters like PCV, Haemoglobin concetration, RBC, WBC count was estimated using sysmex haematology anlyser.Subjects were grouped into underweight, normal, overweight and obese subjects. Stastical significance was determined by ANOVA. Scheffe post-hoc test was used to determine significance while pearson correlation was used to determine relationship between the variables. Data was analysed using SPSS software and presented as mean± standard deviation. Values of P ≤ 0.05 were considered significant.In our study, PCV is statistically increased in overweight and obese individuals as compared to other BMI groups in both males and females. Total leucocyte count was significantly higher in overweight and obese subjects when compared to normal subjects. We found no change in Haemoglobin concentration and RBC count in all BMI groups.In our study we observed, leucocytosis and higher PCV in overweight and obese individual groups when compared to underweight and normal weight BMI groups. There is direct positive correlation between BMI and total leucocyte count. RBC count and haemoglobin concentration shows no statistical significance among all BMI groups.There is need for promotion of a healthy life style, regular exercise, healthy nutrition, stress free life in young population.

scholarly journals Frequency of Genital Infections According to Body Mass Index in Dapagliflozin-treated Patients with Type 2 Diabetes Mellitus

2017 ◽  
Vol 04 (01) ◽  
pp. e1-e4
Author(s):  
Gottfried Rudofsky ◽  
Tanja Haenni ◽  
John Xu ◽  
Eva Johnsson
Keyword(s):  
Type 2 Diabetes ◽  
Body Mass Index ◽  
Body Mass ◽  
The Body ◽  
Baseline Body Mass Index ◽  
Obese Patients ◽  
Genital Infections ◽  
Increased Risk ◽  
Three Body

Abstract Genital infections are associated with sodium glucose co-transporter 2 inhibitors such as dapagliflozin. Since patients with Type 2 diabetes are at increased risk of genital infections, and obesity is a risk factor for infections, obese patients with Type 2 diabetes could be more susceptible to genital infections when treated with sodium glucose co-transporter 2 inhibitors. This pooled dataset assessed the frequency of genital infections according to baseline body mass index in patients treated with dapagliflozin 10 mg. Data were pooled from 13 studies of up to 24 weeks’ duration (dapagliflozin N=2 360; placebo N=2 295). Frequency of genital infections was compared between three body mass index subgroups (<30, ≥30−< 35 and ≥35 kg/m2). Genital infections were reported in 130 (5.5%) patients receiving dapagliflozin and 14 (0.6%) patients receiving placebo; none of which were serious. Genital infections were more common in women (84/130 [64.6%]) than in men (46/130 [35.4%]) treated with dapagliflozin. In the body mass index < 30, ≥ 30−< 35 and ≥ 35 kg/m2 dapagliflozin-treated subgroups, 38/882 (4.3%), 47/796 (5.9%) and 45/682 (6.6%) patients presented with genital infections, respectively. Although the frequency was low overall and relatively similar between subgroups, there was a trend towards an increase in genital infections in patients with a higher body mass index. This trend is unlikely to be clinically relevant or to affect suitability of dapagliflozin as a treatment option for obese patients with Type 2 diabetes, but rather should influence advice and counselling of overweight patients on prevention and treatment of genital infections.

scholarly journals Correlation between serum lipid profile and body mass index in young healthy medical students

2021 ◽  
Vol 8 (2) ◽  
pp. 106-109
Author(s):  
Tejashwini V B ◽  
Ganashree C P
Keyword(s):  
Type 2 Diabetes ◽  
Body Mass Index ◽  
Young Adults ◽  
Medical Students ◽  
Lipid Profile ◽  
The Body ◽  
Cardiovascular Disorders ◽  
Prevalence Of Obesity ◽  
The Mean

Obesity is defined as increased accumulation of fat in various tissues in the body causes impairment in the body. The cause for obesity is imbalance between calories intake and calories expenditure There is increased intake of calorie rich foods and reduced physical activity due to urbanization all over the world.Body mass index is simple index to divide obesity among adults. It is defined as person’s weight in kilograms divided by height in meter squares (m).Obesity and elevated BMI are the major causes for development of chronic diseases like stroke, hypertension, malabsorption syndrome, Type 2 diabetes and other cardiovascular disorders.BMI and obesity are the modifiable risk factors of type 2 diabetes, cardiovascular disorders and hypertension. This study was carried out to correlate the relationship between BMI and lipid profile among young healthy medical students. This study comprises 45 males and 55 females (100 in total) young adults aged between 18 to 25 years. The design for this study was cross-sectional survey. Ethical approval was taken from ethical committee of BMCH, Chitradurga. BMI, lipid profile levels are measured from the subjects. A total of 100 participants were tested. Among them 45 males were males and 55 were females. The mean age of the subjects was 22 years. Among them, 30 were overweight and 17 were obese while, 4 were underweight. The mean BMI was 26.72±3.45 Kg/m. Mean serum cholesterol in 100 students was 147.63 ± 15 mg/dl, mean LDL-C was 85.23±14.8 mg/dl, mean HDL-C was 23.22±5.56 mg/dl and mean triglycerides were 76.6 ±18.5 mg/dl. The mean BMI of students was 22.5 kg/m ±5.5.It was found in our study that prevalence of overweight is the major driving forces in the development of diabetes mellitus, hypertension, metabolic syndrome. Prevalence of obesity is significantly higher among young adults. This prevalence may be due to lack of awareness and unhealthy lifestyles, so health education and more preventive measures should decrease the prevalence of obesity and cardiac risks in our medical college by modifying their lifestyle.

scholarly journals The effect of combination therapy of insulin glargine, metformin, and sitagliptin on insulin secretion, insulin resistance, and metabolic parameters in obese subjects with type 2 diabetes

2016 ◽  
Vol 144 (9-10) ◽  
pp. 497-502
Author(s):  
Teodora Beljic-Zivkovic ◽  
Milica Marjanovic-Petkovic ◽  
Miljanka Vuksanovic ◽  
Ivan Soldatovic ◽  
Dobrila Kanlic ◽  
...  
Keyword(s):  
Insulin Resistance ◽  
Type 2 Diabetes ◽  
Body Mass Index ◽  
Waist Circumference ◽  
Insulin Glargine ◽  
Body Mass ◽  
Fasting Glucose ◽  
C Peptide ◽  
Obese Subjects

Introduction. A combination of drugs is required for treatment of obese subjects with diabetes, due to multiple pathogenic mechanisms implicated in the development of both diabetes and obesity. Objective. Assessment of the effect of sitagliptin added to insulin glargine and metformin, in obese subjects with type 2 diabetes. Methods. A total of 23 obese subjects on metformin and insulin glargine participated in the study. Titration of insulin glargine during a one-month period preceded the addition of 100 mg of sitagliptin daily. Body mass index, waist circumference, fasting, and prandial glucose were measured monthly, lipids and hemoglobin A1c (HbA1c) every three months, insulin, c-peptide and glucagon at the start and after six months of treatment. Homeostatic models for insulin secretion (HOMA B) and insulin resistance (HOMA IR) were calculated. Results. Participants were 58.65 ?} 7.62 years of age with a body mass index of 35.06 ?} 5.15 kg/m2, waist circumference of 115.04 ?} 15.5 cm, and the duration of diabetes of 4.11 ?} 2.57 years. With the titration of insulin glargine, target fasting glucose levels were not achieved. Waist circumference and body mass index decreased during three months of sitagliptin treatment, thereafter remaining stable. HbA1c decreased significantly after three and six months of therapy. C-peptide increased significantly, while glucagon level fell. HOMA indexes were unchanged. Conclusion. Sitagliptin can improve diabetes control and induce modest weight loss in obese subjects poorly controlled on insulin glargine and metformin. Titration of insulin glargine to optimal fasting glucose values is a prerequisite of success of this combination therapy.

CHARACTERISTICS OF BLOOD PARAMETERS OF YAKUT MEN WITH TYPE 2 DIABETES DEPENDING ON THE SOMATOTYPE

2020 ◽  
Vol 22 (11) ◽  
pp. 45-49
Author(s):  
Alekseeva V.A. ◽  
Zolotaryov N.A.
Keyword(s):  
Type 2 Diabetes ◽  
Body Mass Index ◽  
Body Mass ◽  
Statistical Processing ◽  
Blood Parameters ◽  
The Body ◽  
Transverse Diameter ◽  
Diagnostic Laboratory ◽  
Anthropometric Study

The aim of the work was to identify the features of biochemical blood parameters of Yakut men with type 2 diabetes depending on the Rees-Eizenk somatotype. We examined 40 men of yakut nationality with an established diagnosis of "type 2 diabetes", aged 38 to 69 years (average age 57,4 years). The anthropometric study included measurements of body length, body weight, body circumference (chest circumference, waist and buttock circumference), and body diameters (transverse diameter of the chest, anterior-posterior diameter of the chest). The body mass index (BMI) was calculated. Somatotyping was performed using the Rees-Eizenk index. The index value of the examined men was divided into pyknic, normosthenic and asthenic somatotype. Data from the biochemical blood test were copied from the patients ' medical history. All laboratory tests were conducted in the clinical and diagnostic laboratory of the Yakut city clinical hospital. Statistical processing of the obtained scientific material was carried out by the method of variation statistics using the SPSS application software package for Windows (version 17,0). The analysis was performed using parametric and nonparametric statistics. An anthropometric study of men with type 2 diabetes found that half of the subjects were obese according to their body mass index. A somatotypological study on the Rees-Eizenk index found a predominance of individuals with a pyknical somatotype. Asthenic somatotype was not detected in the examined group. More pronounced deviations of biochemical parameters of the pyknic men's blood from the standard parameters were found. The data obtained indicate a greater susceptibility to the development of type 2 diabetes in men with a pyknical somatotype.

Multifaceted Effects of Intermittent Fasting in the Treatment and Prevention of Diabetes, Cancer and Obesity or Other Chronic Diseases

2021 ◽  
Vol 18 ◽  
Author(s):  
Priti Tagde ◽  
Sandeep Tagde ◽  
Tanima Bhattacharya ◽  
Pooja Tagde ◽  
Rokeya Akter ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Cardiovascular Disease ◽  
Body Mass Index ◽  
Chronic Diseases ◽  
The Body ◽  
Intermittent Fasting ◽  
Treatment And Prevention ◽  
Obesity And Diabetes ◽  
Hormonal Imbalance

Background: Obesity and diabetes are global epidemics that result in a slew of co-morbid illnesses. Both have been linked to an increased risk of hormonal imbalance, cancer, and other significant disorders, which are a concerning trend for cancer rates in the backdrop of rising obesity and diabetes rates worldwide. Around one in ten persons in the United States and Canada have serious illnesses correlated with type 2 diabetes and early death. It is believed that the US economy alone spends $245 billion annually. Lifestyle modification with intermittent fasting protocol and proper diet helps lower the blood glucose level and maintain the body mass index and reduced the inflammation in the body which is the main cause for all chronic diseases. Methods: We searched case series, clinical trials relating to type 2 diabetes, insulin resistance, cancer, thyroid, cardiovascular disease or other inflammatory diseases in response to intermittent fasting in the PubMed, MEDLINE, and Google Scholar databases. Objective: In this review, we focused on intermittent fasting-based approaches that are becoming more widely accepted for improving health and reducing unwanted effects in patients with type 2 diabetes, cancer, cardiovascular disease, neurodegenerative disease, obesity, thyroid, and hormonal imbalance, which are fasting intermittently and whether intermittent fasting may be considered as a non-medicinal therapeutic option for persons suffering from chronic diseases. Conclusion : Intermittent fasting successfully reversed the diabetes, thyroid, high blood pressure, elevated lipid level, and maintained the body mass index along and also studies has shown that it has been followed or instructed for the treatment and prevention of cancer and neurodegenerative diseases with dietary interventions.

Influence of the body mass index on the occurrence of falls in patients with type 2 diabetes mellitus

2015 ◽  
Vol 9 (5) ◽  
pp. 522-526 ◽  
Author(s):  
Aline B. Herrera-Rangel ◽  
Catalina Aranda-Moreno ◽  
Teresa Mantilla-Ochoa ◽  
Lilia Zainos-Saucedo ◽  
Kathrine Jáuregui-Renaud
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Body Mass Index ◽  
Type 2 Diabetes Mellitus ◽  
Body Mass ◽  
The Body

scholarly journals Update on the Mechanisms Facilitating Weight Loss and Resolution of Type 2 Diabetes Following Bariatric Surgery

2012 ◽  
Vol 19 (4) ◽  
pp. 425-432
Author(s):  
Cornelia Zetu ◽  
Rubin Munteanu ◽  
Anca Frunză ◽  
Constantin Ionescu-Tîrgovişte
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Bariatric Surgery ◽  
Body Mass Index ◽  
Weight Loss ◽  
Morbidly Obese ◽  
Obese Patients ◽  
Glucose Profiles ◽  
Obese Subjects

AbstractThe prevalence of type 2 diabetes mellitus (T2DM) and obesity is steadily increasingworldwide. To fight the twin pandemics of obesity and T2DM, clinicians need everytool they can get. Major, durable weight loss is uncommon with medical andbehavioral approaches; many diabetes drugs promote weight gain, while using themto obtain better blood glucose profiles increases the risk of hypoglycemia. Bariatricsurgery seems to be the most effective method for promoting major and durableweight loss in obese subjects, leading also to ameliorations of obesity-associated comorbidities,especially T2DM. Currently, indications for bariatric surgery includemorbidly obese patients or patients with a body mass index (BMI) >35 withsignificant co-morbidities. Currently, bariatric surgery (also referred to as“metabolic surgery”) is advocated for the treatment of T2DM even in overweightsubjects who do not meet the current BMI criteria. This review examines the currentevidence regarding the mechanisms of T2DM resolution following bariatric surgery.

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