scholarly journals Asymptomatic COVID 19 infection: An innocent bystander in Mucormycosis or maybe not?

2021 ◽  
Vol 8 (2) ◽  
pp. 182-184
Author(s):  
Liz Mary Paul ◽  
Shamsudeen M ◽  
Shahul Hameed C P ◽  
Lubna Abdul Azeez ◽  
Faris Hussain K N ◽  
...  

We report a case of 48 year old male with past medical history of poorly controlled Diabetes mellitus, Chronic Liver Disease-child Pugh B who came with complaints of left frontal headache and left orbital pain. A clinical diagnosis of possible Rhinorbital Mucormycosis was made and further confirmed by potassium hydroxide (KOH) mount from tissue, which showed broad sparsely septate hyphae and fungal culture grew Rhizopus oryzae. Covid 19 infection was detected as an incidental finding on admission to the hospital. The patient was successfully treated with surgical debridement and liposomal Amphotericin B followed by oral Posaconazole.

Author(s):  
A.P. Mitha ◽  
J.H. Wong ◽  
S.J. du Plessis

A 51-year-old gentleman of Chinese descent presented for neurological evaluation following a two-year history of cervical neck pain associated with left arm numbness. His symptoms were initially stable, but had progressed over the past six months to include weakness of his entire left arm and leg and symptoms of bladder urgency. Two weeks prior to presentation, he suffered repeated falls due to worsening gait difficulties. The past medical history was significant for type II diabetes mellitus.


2022 ◽  
Vol 22 (1) ◽  
Author(s):  
Seyed Ali Tabatabaei ◽  
Soran Aminzade ◽  
Aliasghar Ahmadraji ◽  
Mohammad Soleimani ◽  
Bahram Bohrani Sefidan ◽  
...  

Abstract Background Based on endophthalmitis vitrectomy study, intravitreal injection of antibiotics is preferred for initial management of cases of acute post cataract surgery endophthalmitis (APCE) with presenting vision of hand motions (HM). This study aimed to compare outcomes of early and complete vitrectomy (VIT) and vitreous tap and antibiotic injection (T&I) in cases of APCE presented with vision of HM. Methods In this prospective study, cases of APCE with vision of HM between 2018 and 2020 were enrolled. According to the time of presentation, the patients were arranged into two groups (VIT vs. T&I). Demographic data, elapsed time to developing endophthalmitis, past medical history, microbiology results, complications, and final visual acuity were recorded and analyzed. Results Seventy-six eyes of 76 patients were enrolled. Fifty-three eyes underwent T&I and twenty-three were arranged into the VIT group. Past medical history of 34.2% of patients was significant for diabetes mellitus. There was a statistically significant lower logMAR in VIT group compared to T&I group (diff = 0.14, 95% CI: 0.04 to 0.24, P-value = 0.007). The comparison of the diabetic and non-diabetic patients in both groups showed that the visual outcome was better in non-diabetic cases compared to the diabetic subjects. There was no statistically significant difference between the diabetic and non-diabetic groups regarding the superiority of procedure. Conclusion Based on our results, we could recommend that it’s maybe better to do early and complete vitrectomy as the initial management of APCE with the vision of HM. Past medical history of diabetes mellitus is not a determining factor for choosing initial management between vitrectomy and antibiotic injection.


2019 ◽  
Vol 18 (11) ◽  
pp. 1028-1035
Author(s):  
Farhanah Ahmad Shuhaimi ◽  
Norazmir Md Nor ◽  
Siti Sabariah Buhari ◽  
Emmy Hainida Khairul Ikram ◽  
Ummy Syalshabella Mu Zamri

2020 ◽  
Vol 4 (1) ◽  
pp. 99-100
Author(s):  
Sophia Ahmed ◽  
Romeo Fairley

A 58-year-old male with past medical history of diabetes mellitus presented with pain to the bilateral groin for six weeks. Magnetic resonance imaging of the patient’s lower extremities revealed acute myoedema, and he was diagnosed with myositis secondary to diabetic muscle infarction.


Author(s):  
Dr. Nicholas Gaeto, PGY 2, ◽  
Dr. Glenn Goodwin, PGY 2, D.O. ◽  
Mara Seat, OMS III

A 51-year-old female with a past medical history of poorly controlled diabetes mellitus presented to the emergency department with signs of emphysematous cystitis and pyelonephritis with associated Enterococcus faecalis bacteremia and Candida Glabrata (C.Glabrata) fungemia. She was treated with micafungin and amoxicillin with improvement in her symptoms. During her course she underwent repeat imaging which showed improvement in her cystitis and no obstruction in her bladder. She was discharged on home IV micafungin. She returned to the emergency department the next day with acute urinary obstruction and was found to have a completely obstructing mucus ball in her bladder. This was removed cystoscopically and surgical cultures grew C. glabrata. She was successfully treated with intra-vesicular amphotericin B and was discharged.


2019 ◽  
Vol 14 (4) ◽  
pp. e30-e31
Author(s):  
Taraneh Tofighi ◽  
Karen Lien ◽  
Raphael Rush

         We report the ccase of a 65-year-old woman presenting with urosepsis in the context of a one-week history of progressive right flank pain and a past medical history of type 2 diabetes mellitus. Computed Tomography (CT) demonstrated evidence of emphysematous pyelitis, a rare infection caused by gas-producing bacteria associated with elevated blood glucose. The patient responded well to fluid resuscitation and was discharged home with follow-up arranged for blood sugar management and outpatient lithotripsy addressing obstructive renal calculus.


2020 ◽  
pp. 1-5
Author(s):  
Joana Coutinho ◽  
Catarina Santos ◽  
Joana Coutinho ◽  
Raquel Chorao ◽  
Teofilo Yan

Visceral leishmaniasis is a rare disease in Western countries. We present the case of a 72-year-old male recipient of a related live donor renal transplant 41 years earlier and a past medical history of visceral leishmaniasis, who presented with progressive malaise, diarrhea, weight loss and darkening of skin, 11 months after the first episode. The main finding on blood work was severe hyponatremia and pancytopenia. He was diagnosed with relapsing visceral leishmaniasis and treated with liposomal amphotericin B (L-AmB), reduction of immunosuppressive therapy and supportive therapy. Throughout treatment he had worsening bradycardia and hyponatremia accompanied with liver failure and acute congestive heart failure. The patient survived the leishmaniasis episode but had sequels of chronic liver disease and chronic heart failure. The authors report the case due to its clinical challenge and due to the fact that data on how to treat immunodeficient patients with relapsing leishmaniasis is scarce.


2021 ◽  
pp. 089719002110007
Author(s):  
Kyle A. Weant ◽  
Alexander M. Clendening ◽  
Jeffrey S. Bush

Introduction: Tramadol is an opioid analgesic that binds to mu-opioid receptors and inhibits the uptake of norepinephrine and serotonin. Through its activation of these receptors, it has potential to increase the utilization of glucose and/or decrease hepatic gluconeogenesis. Case Report: A 55-year-old male presents to the Emergency Department (ED) via Emergency Medical Services (EMS) following a self-reported overdose of alprazolam, lorazepam, acetaminophen with codeine, and tramadol. During EMS transport, the patient was found to be hypoglycemic with a glucose of 30 mg/dL and was administered 25 grams of intravenous (IV) dextrose 50% in water. The patient had no past medical history of diabetes mellitus, hypoglycemia, or hyperglycemia and was normoglycemic on his prior presentations to our facility 3 months and 2 years prior. Subsequent analysis found that the patient was negative for acetaminophen, ethanol, salicylates, tricyclics, and lithium. His urinalysis was positive for opiates and benzodiazepines. Upon arrival to the ED, the patient’s blood glucose was 131 mg/dL but subsequently dropped to 73 mg/dL, necessitating the initiation of continuous IV fluids containing dextrose. These fluids were discontinued 3.5 hrs later and the patient was discharged 16 days later. Discussion: This case illustrates that hypoglycemia can be a presenting symptom in patients with an acute overdose of tramadol with no previous history of glycemic dysregulation. Upon presentation it is important to closely monitor serum glucose concentrations to identify hypoglycemia early in order to initiate necessary hypoglycemia protocols.


2021 ◽  
Vol 14 (8) ◽  
pp. e241655
Author(s):  
Swasthi S Kumar ◽  
Animesh Ray ◽  
Naval Kishore Vikram ◽  
Surabhi Vyas

Chronic cavitary pulmonary aspergillosis (CCPA) is a slow destructive type of chronic pulmonary aspergillosis, characterised by multiple pulmonary cavities that develop and expand over several months or years. Pleural involvement in the form of pneumothorax has been rarely reported in CCPA. We report such an unusual case of an immunocompromised male, with a history of chronic cough and fever, presenting with acute onset of shortness of breath. Chest imaging showed bilateral multiple cavitating nodules, ground glass opacities and dense right middle lobe consolidations and right-sided pneumothorax. Bronchoalveolar lavage (BAL) showed septate hyaline hyphae on KOH (potassium hydroxide) staining and fungal culture grew Aspergillus fumigatus. BAL and serum galactomanan were positive and serum IgG for A. fumigatus was 58 MgA/L (0–40MgA/L) confirming the cause of spontaneous secondary pneumothorax in our patient as CCPA.


2015 ◽  
Vol 7 (1) ◽  
pp. 36-38
Author(s):  
Jennifer Yan Fei Chen ◽  
Marianne J. Stroz ◽  
David N. Adam

In this report we describe a unique case of tinea pedis. A 29-year-old man presented with a 3-day history of asymptomatic purpuric papules predominantly on his left foot. Potassium hydroxide preparation demonstrated fungal hyphae and culture yielded Trichophyton mentagrophytes. This patient presented unusually with purpuric papules, unlike the three commonly described types of tinea pedis. Given the morphology, positive potassium hydroxide slide preparation, T. mentagrophytes on fungal culture and clinical response to ketoconazole cream, we conclude that this represents a unique variant of tinea pedis. We recognize that even common dermatological diagnoses can have unique presentations, and it is important for clinicians to maintain a broad differential for new dermatologic cases.


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