scholarly journals Outfacing second wave of pandemic in COVID-19 positive mothers at Gandhi hospital

2021 ◽  
Vol 8 (4) ◽  
pp. 548-552
Author(s):  
Amreen Sharif ◽  
Vellanki Janaki
Keyword(s):  
Rna Virus ◽  
Discharge Rate ◽  
Tertiary Care ◽  
Medical Advice ◽  
Severe Illness ◽  
Tertiary Care Centre ◽  
Safe Delivery ◽  
Labour Room ◽  
Second Wave ◽  
In Pregnancy

The novel coronavirus is a single stranded RNA virus with spike proteins triggering an immune response leading to cytokine storm and coagulopathy. Pregnancy is an immunocompromised and hypercoagulable state, with predisposition to severe illness. An insight into impact of COVID-19 in pregnancy is essential to combat its future.This study was conducted at a tertiary care centre. Analytical study was conducted from the data collected regarding COVID-19 positive labour room admissions, deliveries and deaths during the second wave of pandemic.There was a discharge rate of 88.14% after safe delivery. Among COVID-19 maternal mortalities, most deaths were due to ARDS. Quick SOFA score was a good predictor for morbidity and mortality. Deranged coagulation profile and D-Dimer levels more than 500 ng/ml were good predictors of mortality. Silent hypoxia needs to be identified and corrected at admission. Delay in seeking medical advice was a major contributory risk factor.Increasingawareness among public about seeking medical advice during early stages of disease. Early identification and treatment according to latest guidelines for a positive outcome.Making aware the policy makers regarding risk-benefits of vaccination in mothers can come a long way in changing the fate of COVID-19 in pregnancy.

H1N1 in Pregnancy: A Tertiary Care Centre Experience

2011 ◽  
Vol 33 (7) ◽  
pp. 698-704 ◽  
Author(s):  
Ann Kinga Malinowski ◽  
Allison McGeer ◽  
Julie Robertson ◽  
Mathew Sermer ◽  
Dan Farine ◽  
...  
Keyword(s):  
Tertiary Care ◽  
Care Centre ◽  
Tertiary Care Centre ◽  
In Pregnancy

scholarly journals High proportion of overt diabetes mellitus in pregnancy and missed opportunity for early detection of diabetes at a tertiary care centre in Pakistan

2019 ◽  
Vol 36 (ICON-Suppl) ◽  
Author(s):  
Aisha Syed Wali ◽  
Raheela Rafique ◽  
Sundus Iftikhar ◽  
Rakhshinda Ambreen ◽  
Mohammad Yawar Yakoob
Keyword(s):  
Diabetes Mellitus ◽  
Early Detection ◽  
Tertiary Care ◽  
Fasting Blood Glucose ◽  
Care Centre ◽  
Tertiary Care Centre ◽  
Family History Of Diabetes ◽  
Overt Diabetes ◽  
Missed Opportunity ◽  
In Pregnancy

Objectives: To determine the frequency of diabetes in pregnancy (DIP), namely pre-gestational, gestational (GDM) and overt diabetes mellitus (DM) in women registered for delivery. Methods: A retrospective chart review of antenatal women registered between January 01 to August 31, 2017 was performed. Gestational age, diagnosis of DIP, glucose levels at diagnosis and other relevant data was extracted. The effect of various fasting blood glucose (FBG) thresholds for diagnosis of DIP was assessed. Results: DIP was diagnosed in 21.8% women (pre-gestational: 2%, GDM: 81.2%, overt DM: 16.8%). In early registrants, 30.2% were detected through screening. However, 55.3% of women registered late. Women with pre-gestational DM were older, had more miscarriages, and greater personal and family history of diabetes versus GDM and overt DM. Raising the diagnostic threshold of FBG from 92 mg/dl to 95 mg/dl missed three women (0.1%) and to 105 mg/dl, missed six women (0.2%). Conclusion: We observed a high proportion of overt DM. In early registrants, almost one third of DIP was diagnosed in the first half of pregnancy, an opportunity missed in late registrants. Altering diagnostic thresholds of DIP affected only a small proportion of women. doi: https://doi.org/10.12669/pjms.36.ICON-Suppl.1723 How to cite this:Wali AS, Rafique R, Iftikhar S, Ambreen R, Yakoob MY. High proportion of overt diabetes mellitus in pregnancy and missed opportunity for early detection of diabetes at a tertiary care centre in Pakistan. Pak J Med Sci. Special Supplement ICON 2020. 2020;36(1):S38-S43. doi: https://doi.org/10.12669/pjms.36.ICON-Suppl.1723 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

scholarly journals Prevalence of various dermatoses in pregnancy at a tertiary care centre in Moradabad, Uttar Pradesh, India: an observational study

2019 ◽  
Vol 8 (2) ◽  
pp. 425
Author(s):  
Shruti Uniyal ◽  
Ritika Agarwal ◽  
Nupur Nandi ◽  
Pulkit Jain
Keyword(s):  
Observational Study ◽  
Low Socioeconomic Status ◽  
Treatment Options ◽  
Tertiary Care ◽  
Liver Function Tests ◽  
Skin Lesions ◽  
Personal Hygiene ◽  
Tertiary Care Centre ◽  
Palmar Erythema ◽  
In Pregnancy

Background: This was a prospective study which was done to observe various skin lesions in pregnancy and to determine the most likely causes and their incidence in antenatal patients, it was noticed that many women in our institute were having pregnancy related cutaneous complaints thus this observational study was carried out so that better preventive measures and treatment options could be provided to these patients.Methods: Study was conducted in out-patient department of Obstetrics and Gynaecology, TMU, Moradabad. All ANC cases between October 2017 to September 2018 having any type of dermatoses were included in the study irrespective of gestational age. 6348 patients appeared in OPD in the given time period out of which 1256 were included. In case of pruritus, liver function tests were done with USG whole abdomen and patients were reviewed by physician if required. Screening with VDRL, HCV, HbSAg and ELISA for HIV was done in all. Results were tabulated and analyzed.Results: 50.8% primi gravidas ,49.2% multi gravidas. age range 18-38 years. 29.3% presented in third trimester ,25.6% presented in second trimester. Physiological changes seen in all cases, 8.68% specific dermatoses of pregnancy. 40.4 % no complaints, 5.65% melasma, 90.8% hyperpigmentation, 94.6% linea nigra. Secondary areola 89.3%,striae 80.3% out of which 38.9%- primi gravidas and 41.40% -multi gravidas. 92.9% no change in hair density. Montgomery’s tubercles 30-50% of cases. spiders nevi 67%. No cases of palmar erythema. Pruritus gravidarum 38.53%. PUPPP 28.4%. Pemphigoid Gestationis 9.17%. Prurigo of pregnancy 18.34%. Pruritic folliculitis 1.8%. Eczema in pregnancy : pre-existing in 3.7% , out of which exacerbation 1, 3 unaffected. 3 chicken pox.1 filariasis.24 herpetic lesions (herpes simplex).1 scleroderma.17.27% pre-existing taenia infection . Scabies 20.46%.11 0.87% dual infection (scabies-taenia).Conclusions: This study highlights high prevalence of community acquired infections in our region like taenia, scabies giving rise to skin lesions in Antenatal women. Moreover, it highlights a probable association between the prevalence of skin lesions with factors like poor personal hygiene, overcrowding, low socioeconomic status, anaemia and poor nutritional status.

scholarly journals Spectrum of dengue morbidity in pregnancy and its impact on maternal and perinatal outcome

2019 ◽  
Vol 8 (4) ◽  
pp. 1511
Author(s):  
Anuradha G. ◽  
Sandya M. R. ◽  
Shirley George
Keyword(s):  
Dengue Infection ◽  
Tertiary Care ◽  
Dengue Shock Syndrome ◽  
Severe Form ◽  
Tertiary Care Centre ◽  
College Hospital ◽  
Medical College ◽  
Still Births ◽  
Record Review ◽  
In Pregnancy

Background: Dengue is a vector borne viral infection with seasonal outbreaks every year. The spectrum varies from just a febrile morbidity to the severe form of dengue shock syndrome (DSS). The objective of the present study was to study the influence of dengue fever on pregnancy and to analyze the maternal and perinatal outcome.Methods: Thirty-six pregnant women beyond 28weeks of gestation who tested positive for dengue infection were retrospectively analyzed during a 5year study period (Jan 2014-Dec 2018). The study was conducted in the Department of OBGYN St John’s Medical College Hospital, Bangalore. Thirty-three of these patients delivered at St John’s and there were three postpartum referral cases. The necessary data was obtained by patient record review. The data was analyzed using SPSS and the results were expressed as Mean±SD and percentages.Results: Out of 36 women analyzed the mean age was found to be 23.93±4.5 years. Majority were primigravidae (58.3%). The most common clinical manifestation was fever seen in 47.2%. Twenty five percent of patients had platelet count of <20,000 on admission. Overall 66% of the patients required transfusion. Nearly fifty three percent of the patients had vaginal delivery. There were 4 maternal mortalities (11.1%) and 2 perinatal mortalities (5.5%) both were still births in the present study.Conclusions: Dengue infection in pregnancy was associated with increased maternal and perinatal morbidity as well as mortality. The severity of the infection has direct impact on the outcome. Hence early diagnosis and prompt management in a tertiary care centre, with multidisciplinary approach improves the outcome and minimizes the complications.

scholarly journals A study to determine the prevalence of urinary incontinence in antenatal women at a tertiary care centre in central India

2020 ◽  
Vol 9 (3) ◽  
pp. 956
Author(s):  
Deepa Joshi ◽  
Sheetal Achale ◽  
Nilesh Dalal ◽  
Alka Patel
Keyword(s):  
Urinary Incontinence ◽  
Pregnant Women ◽  
Indian Subcontinent ◽  
Tertiary Care ◽  
Previous History ◽  
Case Report Form ◽  
Tertiary Care Centre ◽  
Cross Sectional ◽  
Pregnancy And Postpartum ◽  
In Pregnancy

Background: Urinary incontinence is a common condition in pregnancy and postpartum. There are more than a thousand articles on urinary incontinence (UI) in pregnancy but very limited literature from Indian subcontinent is available. Incidence and prevalence figures of UI in association with pregnancy vary substantially. Not many reviews have focused solely on incidence and prevalence of UI in association with pregnancy. Prevalence of UI in pregnancy ranges from 32% to 64%.Methods: A cross sectional observational study was conducted in the department of obstetrics and gynecology, MGM Medical College and M.Y. Hospital, Indore over the period of 6 months on 1000 pregnant women who were following antenatal care (ANC) clinic. Pregnant women, who were severely sick, diagnosed with kidney or urinary infection and vaginal infections women were excluded from the study. The data were collected using a structured questionnaire. After the purpose of the study was explained, written consent was obtained from each voluntary participant. This study was approved by institutional ethical committee. The data was recorded in predesign coded case report form and statistical analysis was performed using the STATA 12.1.Results: In the present study the prevalence of urinary incontinence reported is 16.4% of women during pregnancy.Conclusions: In this study the prevalence of UI during current pregnancy was found to be lower compared to previous studies conducted. The previous history of surgery, constipation, obesity and respiratory problems were found to be significantly associated with UI during pregnancy.

scholarly journals A comparative study of oral nifedipine and intravenous labetalol in control of acute hypertension in severe pre-eclampsia and eclampsia

2018 ◽  
Vol 7 (2) ◽  
pp. 719
Author(s):  
Yogita Gavit ◽  
Deepika Sharma ◽  
Pratibha V. Dixit
Keyword(s):  
Sample Size ◽  
Severe Hypertension ◽  
Tertiary Care ◽  
Hypertensive Disorder ◽  
Tertiary Care Centre ◽  
Acute Hypertension ◽  
Maternal Morbidity And Mortality ◽  
Life Threatening ◽  
Hypertensive Disorder Of Pregnancy ◽  
Labour Room

Background: This study was conducted to compare oral Nifedipine and intravenous Labetalol in control of acute hypertension in severe pre-eclampsia and eclampsia. This study was observational study with 80 sample size in which 40 sample size treated with intravenous Labetalol and other 40 sample size treated with oral Nifedipine. The maternal and perinatal outcome in two groups sample size with oral Nifedipine and intravenous Labetalol compared and found that nevertheless these results do establish oral Nifedipine as an alternative to IV Labetalol in lowering BP in acute severe hypertension. In summary oral Nifedipine may be preferable as it has a convenient dosing pattern orally.Methods: The present study was conducted in tertiary care centre Mumbai from June 2016 to October 2016. All pregnant woman diagnosed with acute hypertension in severe pre-eclampsia and eclampsia in labour room were enrolled in the study.Results: In the present study oral Nifedipine as an alternative to IV Labetalol in lowering BP in acute severe hypertension. In summary oral Nifedipine may be preferable as it has a convenient dosing pattern orally.Conclusions: A hypertensive disorder of pregnancy is one of the life-threatening complication encountered in obstetrics and globally is major cause of maternal morbidity and mortality. Management of acute severe hypertension in pregnancy is a challenging task. Present study compares the efficacy of oral Nifedipine and IV Labetalol in reaching the therapeutic goal. From the results of this study we can well conclude that oral Nifedipine is more efficacious.

scholarly journals Impact and outcome of cardiac diseases in pregnancy

2020 ◽  
Vol 10 (1) ◽  
pp. 102
Author(s):  
Gira Dabhi ◽  
Jignesh Chauhan ◽  
Munjal Pandya ◽  
Rahul Sinhar
Keyword(s):  
Heart Disease ◽  
Cardiac Disease ◽  
Nyha Class ◽  
Demographic Data ◽  
Tertiary Care ◽  
Mode Of Delivery ◽  
Close Monitoring ◽  
Care Hospital ◽  
Tertiary Care Centre ◽  
In Pregnancy

Background: Present study done to study incidence, effect of pregnancy on cardiac disease and vice-versa and feto-maternal outcome in patients with cardiac disease in pregnancy at tertiary care hospital.Methods: It’s a retrospective observational study conducted in Department of OBGY at tertiary care hospital between 01 June 2019 to 31 May 2020. 28 cases of cardiac disease out of 8659 patients registered included in the study. Demographic data like age, parity, etiological factors of cardiac disease, mode of delivery, neonatal outcome noted from case records.Results: In study, 32% were unregistered cases and 10.7% had never sought any medical care before. Majority (53.6%) cases belonged to 20-25 years. Heart disease noted to be more in primipara (35.7%). 71.4% belonged to NYHA class 1+2 and had a relatively uneventful peripartum period. Majority (53.6%) patients had rheumatic valvular disease. Cases of Congenital heart disease were17.8%, pulmonary artery hypertension was 25%, Maternal mortality were 2(7.2%). 46.5% women delivered with caesarean section. PIH (18%) and anemia (7.2%) were most commonly associated conditions. 85.6% women delivered live newborns and full term, pre-term deliveries and IUGR were 71.4%, 17.8% and 10.7% respectively.Conclusions: Rheumatic origin is the most common cardiac disease associated with pregnancy. The availability of early diagnostic techniques and reference to tertiary care centre, timely admission and close monitoring of patient and delivery with multidisciplinary approach include specialized cardiologic care, high risk obstetric support and neonatology expertise can minimize feto-maternal morbidity and mortality. Pre-conceptional counselling, regular antenatal check-ups and contraceptive advice must be included in counselling part.

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