scholarly journals Comparative analysis of the post-operative anti-inflammatory effect of topical 0.1% dexamethasone sodium eye drops, topical 1% prednisolone acetate eye drops and difluprednate 0.05% topical eye drops after small incision cataract surgery at a tertiary eye care institute in India

2021 ◽  
Vol 7 (1) ◽  
pp. 71-76
Author(s):  
Abhilash B ◽  
Mahesh Babu
Keyword(s):  
Comparative Analysis ◽  
Cataract Surgery ◽  
Prednisolone Acetate ◽  
Eye Drops ◽  
Eye Care ◽  
Small Incision Cataract Surgery ◽  
Small Incision ◽  
Care Institute ◽  
Anti Inflammatory ◽  
Inflammatory Effect

scholarly journals Topical bromfenac versus prednisolone: post cataract surgery safety and efficacy

2020 ◽  
Vol 7 (4) ◽  
pp. 1375
Author(s):  
Harish R. Trivedi ◽  
Harsha Maheshwari
Keyword(s):  
Intraocular Pressure ◽  
Cataract Surgery ◽  
Macular Oedema ◽  
Cystoid Macular Oedema ◽  
Posterior Chamber ◽  
Prednisolone Acetate ◽  
Eye Drops ◽  
Small Incision Cataract Surgery ◽  
Postoperative Inflammation ◽  
Anti Inflammatory

Background: Cataract surgery can result in postoperative inflammation which increases the risk of complications like increased intraocular pressure (IOP), uveitis and cystoid macular oedema. We aim to evaluate the effectiveness of topical non-steroidal anti-inflammatory drug bromfenac and topical prednisolone in controlling intraocular inflammation after uncomplicated cataract surgery and compare intraocular pressure (IOP) differences, degrees of anterior chamber inflammation and macular oedema between two different treatments.Methods: 100 patients undergoing manual small incision cataract surgery with PMMA posterior chamber intraocular lens implantation were randomly assigned to receive either Bromfenac (0.09%) eye drops or prednisolone acetate (1%) eye suspension as their postoperative anti-inflammatory medication with 50 cases in each group. The patients were examined at the day 1, day 7, day 15, and day 30 after surgery. Postoperative inflammation was evaluated subjectively by intraocular pressure, slit-lamp assessment of signs of inflammation in the form of aqueous cells and flare and optical coherence tomography to rule out post-operative macular oedema.Results: Both the drugs are equally effective in controlling post-operative inflammation and post-operative cystoid macular oedema.Conclusions: Bromfenac (0.09%) is an effective drug in controlling ocular inflammation after un-complicated cataract surgery having effect similar to topical Prednisolone acetate (1%) with minimal side effects and less frequent dosing.

scholarly journals A 50-year-old woman presented with severe reduction of vision and recurrent pain in right eye following cataract surgery

2019 ◽  
Vol 12 (3) ◽  
pp. 154-158
Author(s):  
Md. Abdul Khaleque ◽  
Mohammad Afzal Mahfuzullah ◽  
Suprokash Sarkar ◽  
Abir Bin Sajj ◽  
Md. Shafiqul Islam
Keyword(s):  
Cataract Surgery ◽  
Eye Drops ◽  
Government Hospital ◽  
Recurrent Pain ◽  
Small Incision Cataract Surgery ◽  
Iol Implantation ◽  
Small Incision ◽  
Department Of Ophthalmology ◽  
Severe Reduction ◽  
The Right

This article has no abstract. The first 100 words appear below: A 50-year-old female, hailing from Patuakhali, was admitted at the Department of Ophthalmology for the management of severe reduction of vision and pain at the right eye for the last 7 months following cataract surgery at a government hospital. Her cataract surgery (small incision cataract surgery with PC-IOL implantation) of the right eye was performed on October 28, 2018. On the first post-operative day, she developed pain, redness and severe reduction of vision in the right eye. The following day, she was discharged with the advice of some medications like moxifloxacin, dexamethasone, bromfenac eye drops and oral acetazolamide and potassium.

scholarly journals Comparison of efficacy of difluprednate 0.05% vs dexamethasone 0.1% eye drops in inflammation associated with small incision cataract surgery

2017 ◽  
Vol 6 (6) ◽  
pp. 1526
Author(s):  
Preet Sood ◽  
Manmohan Bhanot
Keyword(s):  
Cataract Surgery ◽  
Drug Administration ◽  
Ocular Inflammation ◽  
Eye Drops ◽  
Parallel Study ◽  
Small Incision Cataract Surgery ◽  
Small Incision ◽  
Dexamethasone Group ◽  
The Cost ◽  
Single Blind

Background: Post operative ocular inflammation is a common happening after any type of surgery. Corticosteroids have been used to treat ocular inflammation however, they carry a risk of side effects, particularily an increase in IOP. A newer steroid, difluprednate is found to be safe than dexamethasone.Methods: Total 120 patient undergoing small incision cataract surgery was enrolled in this prospective, randomized and single blind (investigator masked) parallel study. Either of the two eye drops (dexamethasone/difluprednate) were prescribed post operatively. Patients were examined on postoperative day 1, 7, 14 and 28 for - Intraocular pressure, anterior chamber cells and flare with slit lamp examination.Results: As difluprednate was found effective in reducing pain in 62% of the patients on day 3 as compared to dexamethasone group on day 7 i.e.76% of the patients. Both the drugs has no significant effect on the intraocular pressure.Conclusions: Patients in difluprednate preparation have shown good compliance owing to the lesser frequency of drug administration. Better tolerability because of the emulsion form is also an encouraging factor. The only discouraging factor for difluprednate preparation is the cost. As the frequency of drug administration as compared to dexamethasone is less (QID), it is compromised a bit.

scholarly journals Outcome of cluster endophthalmitis in western plain region of Nepal

1970 ◽  
Vol 8 (1) ◽  
pp. 102-108 ◽  
Author(s):  
S Bajimaya ◽  
I Kansakar ◽  
BR Sharma ◽  
R Byanju
Keyword(s):  
Visual Acuity ◽  
Cataract Surgery ◽  
Case Series ◽  
Visual Outcome ◽  
High Volume ◽  
Prednisolone Acetate ◽  
Sensitivity Testing ◽  
Small Incision Cataract Surgery ◽  
Small Incision ◽  
Oral Ciprofloxacin

Background: Post-operative endophthalmitis remains one of the most visually devastating complications of cataract surgery. Cluster endophthalmitis is defined as five or more cases of endophthalmitis occurring on a particular day in a single operating room in one centre. Excessive inflammation, particularly in the early post-operative phase, should be regarded as infective endophthalmitis. Early diagnosis and immediate intervention in such case, lead to salvage of eye as well as better visual outcome. Objective: To find out the causative organisms and visual outcome after an outbreak of post-operative endophthalmitis in high volume cataract surgical centre. Materials and methods: Retrospective, interventional case series of 19 patients with acute post-operative endophthalmitis after manual small incision cataract surgery in a single day, underwent vitreous tap and received intravitreal Vancomycin, amikacin and Dexamethasone. Subconjunctival vancomycin was given at the end of the procedure. Vitreous samples were stained using Grams stain, Giemsa stain and KOH mount. Samples were sent to the hospital's microbiology laboratory for culture and sensitivity testing. All patients received intravenous ciprofloxacin for 3 days and oral ciprofloxacin for 7 days. Topical Prednisolone acetate, Ofloxacin, Gentamycin and atropine were given to all patients. Patients were followed up till 6 weeks. Results: 10 eyes had vitreous tap culture negative (52.6%) where as 9 eyes (47.4%) had bacterial culture growth. The culture reports showed 4 cases (21%) of Staphylococcus epidermidis, 3 cases (15.8%) of Staphylococcus aureus and 2 cases (10.5%) of mixed growth. 48 hours after the intervention, 15 patients improved clinically. On sixth week follow up, 7 eyes (37%) had visual acuity better than 6/18, 7 eyes had 6/18 to 6/60 and 5 eyes had visual acuity between 1/60 to 5/60. Conclusion: Intravitreal antibiotics and steroid, along with systemic ciprofloxacin and subconjunctival vancomycin has good visual outcome for post operative cluster endophthalmitis. Key words: Manual small incision cataract surgery; Cluster Endophthalmitis; Nepal DOI: 10.3126/kumj.v8i1.3232 Kathmandu University Medical Journal (2010), Vol. 8, No. 1, Issue 29, 102-108

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