scholarly journals Clinical profile of isolated systolic hypertension in elderly

2021 ◽  
Vol 11 (2) ◽  
pp. 245-252
Author(s):  
Asmita Samal ◽  
J S Dhadwad ◽  
Varun Tiwari ◽  
Narendran Sairam ◽  
Namrata Chaware ◽  
...  
Keyword(s):  
Public Health ◽  
Blood Pressure ◽  
Systolic Hypertension ◽  
The Elderly ◽  
Health Concern ◽  
Intervention Trial ◽  
Isolated Systolic Hypertension ◽  
Public Health Concern ◽  
Mortality And Morbidity ◽  
Practicing Physicians

Isolated systolic hypertension is the most common hemodynamic form of hypertension in the elderly. With a rapidly aging population, the prevalence of hypertension, particularly isolated systolic hypertension, is increasing steadily. Isolated systolic hypertension is associated with substantial mortality and morbidity, particularly of cerebrovascular disease. It is a rapidly growing public health concern and its management continues to remain a challenge to practicing physicians. Recent studies like the Systolic Blood Pressure Intervention Trial (SPRINT) and Heart Outcomes Prevention Evaluation (HOPE)-3 have implications for antihypertensive therapy in general and for the management of isolated systolic hypertension in particular.

Arterial hypertension + past stroke – a case report

2021 ◽  
Vol 14 (3) ◽  
pp. 324-326
Author(s):  
Maria Łukasiewicz ◽  
Marta Swarowska-Skuza
Keyword(s):  
Blood Pressure ◽  
Case Report ◽  
Chronic Disease ◽  
Side Effects ◽  
Arterial Hypertension ◽  
Antihypertensive Therapy ◽  
Systolic Hypertension ◽  
The Elderly ◽  
Isolated Systolic Hypertension ◽  
Special Group

Arterial hypertension, as a very widespread chronic disease, and thus differing in both pathomechanism and course in patients, requires a significant individualization of pharmacotherapy. One such special group is the elderly. Both the low-renin pathomechanism of arterial hypertension and its phenotype (isolated systolic hypertension) imply the choice of a specific pharmacotherapy. Additionally, in this group, side effects should be observed much more vigilantly, while target blood pressure values should be treated more liberally. An example of antihypertensive therapy in a patient belonging to the group described is presented in the following case.

scholarly journals Autophagy Modulation in Mammarenavirus Infection

2020 ◽  
Vol 4 (4) ◽  
pp. 45-51
Author(s):  
Giovanna Gallo ◽  
Julieta Roldán ◽  
Laura Delgui
Keyword(s):  
Public Health ◽  
High Mortality ◽  
Metabolic Pathway ◽  
New World ◽  
Stress Conditions ◽  
Health Concern ◽  
Public Health Concern ◽  
Cellular Homeostasis ◽  
Old World ◽  
Mortality And Morbidity

Mammarenavirus genus groups viruses causing human haemorrhagic diseases, including the New World (NW) Junín virus (JUNV), and the Old World (OW) viruses Lassa (LASV), among others. The high mortality and morbidity rates associated to pathogenic mammarenaviruses, the absence of vaccines and the constant threat of new emerging species, make these viruses a public health concern in endemic areas. Autophagy is a widely-known intracellular metabolic pathway involved in maintaining the cellular homeostasis in response to several stress conditions.

scholarly journals Integrated Diabetic Clinic in a Rural Hospital of Nepal

2019 ◽  
Vol 2 (1) ◽  
pp. 77-78
Author(s):  
Niresh Thapa ◽  
Muna Maharjan
Keyword(s):  
Public Health ◽  
Health Care ◽  
Developing Countries ◽  
Cost Effective ◽  
Rural Setting ◽  
Health Concern ◽  
Public Health Concern ◽  
Mortality And Morbidity ◽  
Important Public Health ◽  
Diabetic Clinic

Diabetes is an important public health concern which is increasing rapidly in developing countries. It is challenging to prevent and manage diabetes in a rural setting. The Integrated Diabetic Clinic is comprehensive diabetes care under one roof. Its aim is to provide efficient accessible and affordable comprehensive care. It will make a huge difference in the management of diabetes. This clinic will play a major role in unifying different aspects of health care under one roof and offer the most comprehensive and cost-effective accessible health care to minimize mortality and morbidity associated with diabetes.

scholarly journals Target Blood Pressure for Treatment of Isolated Systolic Hypertension in the Elderly

Hypertension ◽  
2010 ◽  
Vol 56 (2) ◽  
pp. 196-202 ◽  
Author(s):  
Toshio Ogihara ◽  
Takao Saruta ◽  
Hiromi Rakugi ◽  
Hiroaki Matsuoka ◽  
Kazuaki Shimamoto ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Systolic Hypertension ◽  
The Elderly ◽  
Target Blood Pressure ◽  
Isolated Systolic Hypertension

Blood Pressure and Hypertension among Adult Savara Tribals of Visakhapatnam, Andhra Pradesh, India: A Public Health Concern

2014 ◽  
Vol 5 (1) ◽  
pp. 96
Author(s):  
Isukapatla Arjun Rao ◽  
Adimoolam Chandrasekhar ◽  
Venugopal Pulamgatta ◽  
Subal Das ◽  
Kaushik Bose
Keyword(s):  
Public Health ◽  
Blood Pressure ◽  
Andhra Pradesh ◽  
Health Concern ◽  
Public Health Concern

scholarly journals The Prevalence and Risk Factors of Isolated Systolic Hypertension Among Elderly Chinese Population

2020 ◽  
Author(s):  
QingKun Zheng ◽  
Pengshun Rong ◽  
Xiaobo Huang ◽  
Yang Zhang ◽  
Jianxiong Liu ◽  
...  
Keyword(s):  
Risk Factors ◽  
Blood Pressure ◽  
Physical Exercise ◽  
Chinese Population ◽  
Systolic Hypertension ◽  
Multivariate Logistic Regression Analysis ◽  
The Elderly ◽  
Cluster Sampling ◽  
Isolated Systolic Hypertension ◽  
Elderly Chinese

Abstract Objective To investigate the prevalence status of the isolated systolic hypertension (ISH) among the elderly Chinese population and analyze risk factors of ISH. Methods The survey was conducted from September 2015 to September 2016 enrolling 1269 people aging above 80 in the urban community in Chengdu, China. The participants were recruited by using a stratified cluster sampling method. The average blood pressure of an individual was obtained by using a standardized mercury sphygmomanometer to measure the blood pressure twice after a 10-minute seated rest. Results The prevalence of ISH was 53.0% among the elderly population; the ISH was accounted for 82.2% of all hypertension cases. The prevalence of ISH of males and females was 54.7% and 51.5%, respectively, without significant differences (P = 0.25). The prevalence of ISH in the 80–84 group, 85–89 group, and > 90 group were 52.5%, 53.0%, and 60.0%, respectively without significant differences (P for trend = 0.36). Multivariate logistic regression analysis showed that drinking alcoholic, obesity, and heart rate (HR) > 75 beats/min were all positively correlated to the incident of ISH; however, physical exercise was negatively correlated to the occurrence of ISH. Conclusion 53.0% of the elderly Chinese population aged above 80 has ISH. The gender and physical exercise are not the independent risk factor of ISH. But drinking alcoholic, obesity and HR > 75 are significantly related to the occurrence of ISH.

Arterial stiffness: from isolated systolic hypertension to syncope

ESC CardioMed ◽  
2018 ◽  
pp. 2971-2976
Author(s):  
Jerzy Gąsowski ◽  
Chirag Bavishi ◽  
Franz H Messerli
Keyword(s):  
Blood Pressure ◽  
Pulse Pressure ◽  
Systolic Hypertension ◽  
Pulse Wave ◽  
Angiotensin Receptor Blockers ◽  
The Elderly ◽  
Channel Blockers ◽  
Isolated Systolic Hypertension ◽  
Converting Enzyme Inhibitors ◽  
European Guidelines

Isolated systolic hypertension (ISH) is the predominant form of hypertension in the elderly. The pathophysiology includes a plethora of factors; however, the stiffening of large arteries, leading to wider pulse pressure and faster propagation of the pressure pulse wave, are at the core of the disease. It has been shown that higher systolic blood pressure (SBP), pulse pressure, and pulse wave velocity are associated with a greater risk of cardiovascular complications, including a greater risk of dementia. In elderly patients, the relationship between SBP and the risk of mortality starts increasing at about 160 mmHg. A number of clinical trials were performed in populations of patients which included the elderly, however only four trials were specifically dedicated to answer the question of whether the active treatment of ISH (SHEP, Syst-Eur, Syst-China) or treatment of octogenarian hypertensive patients (HYVET) lowers cardiovascular risk in the elderly patient. They all showed that regimens based on thiazide-like diuretics, dihydropyridine calcium channel blockers, or angiotensin-converting enzyme inhibitors are capable of reducing the risk along with the appropriate reduction of SBP. This is widely reflected in the current European guidelines, with the addition of angiotensin receptor blockers. Nevertheless, the debate on the appropriate blood pressure goal is ongoing. However, none of the trials in the elderly had an average SBP lowered to less than 140 mmHg, and the overwhelming evidence suggests that in patients above the age of 70 with overt cardiovascular disease, a SBP less than 130 mmHg may be associated with an increase in risk.

scholarly journals PREVALENCE OF HYPERTENSION AMONG ELDERLY RESIDING IN SLUMS OF WEST

2018 ◽  
Vol 11 (4) ◽  
pp. 337
Author(s):  
Zaozianlungliu Gonmei ◽  
Supriya Dwivedi ◽  
Gurudayal Singh Toteja ◽  
Karuna Singh ◽  
Naval Kishore Vikram
Keyword(s):  
Blood Pressure ◽  
Systolic Hypertension ◽  
Elderly Population ◽  
Lifestyle Modification ◽  
The Elderly ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Isolated Systolic Hypertension ◽  
Health Checkup ◽  
Cross Sectional

 Objective: The present study was carried out to assess the prevalence of hypertension among elderly in slums of West Delhi.Methods: A cross-sectional study was carried out among 202 elderly residing in urban slums of West Delhi. Hypertension was classified as per JNC VII criteria. Blood pressure was measured twice using digital machine (OMRON) after an interval of 5 min. The data obtained were analyzed for percent prevalence, mean, standard deviation, and median.Results: The overall prevalence of hypertension was 49.1%; higher among male (56.0%) than female (41.9%). The prevalence of Stage I, Stage II, and isolated systolic hypertension was 30.7%, 18.8%, and 47%, respectively.Conclusion: Almost half of the elderly population in slums was hypertensive. Periodical health checkup and management through treatment and dietary and lifestyle modification is needed. 

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