scholarly journals Clinicopathological Study of Lesions of Bone - A Hospital-Based Study

2020 ◽  
Vol 7 (39) ◽  
pp. 2161-2164
Author(s):  
Prasanta Kumar Das ◽  
Bidyut Dutta ◽  
Jabin Musfique ◽  
Partha Pratim Das
Keyword(s):  
Histopathological Examination ◽  
Clinical History ◽  
Malignant Tumour ◽  
Bone Lesions ◽  
Body Parts ◽  
Malignant Tumours ◽  
Female Ratio ◽  
Neoplastic Lesion ◽  
Detailed Clinical History ◽  
Benign Tumours

BACKGROUND A spectrum of pathological bone lesions can present in any form from inflammatory to neoplastic. These lesions are diverse in their clinical and morphological features and range in behaviour from innocuous to rapidly fatal. Accurate diagnosis, proper staging and appropriate treatment are thus necessary to ensure maximum patient survival and maintain optimal function of the affected body parts. We wanted to determine the pattern of various bone lesions and their relative frequency. METHODS This is a hospital based prospective study. After obtaining detailed clinical history, and examination, biopsies were received in 10 % formalin and histopathological examination was done. RESULTS The maximum number of bone lesions occurred in second decade of life. Out of 91 histopathologically diagnosed bone lesions, 54 (59.3%) were males and 37 (40.7 %) were females, with a male to female ratio of 1.5 : 1. Age ranged from 6 ‑ 70 years. Nonneoplastic lesions accounted for 45.1 %, while neoplastic lesions accounted for 54.9 %. Chronic osteomyelitis was the most common non-neoplastic lesion encountered with 25 cases (27.4 %). Out of 50 cases of bone tumours, benign tumours accounted for 34.1 %, while malignant tumours accounted for 20.9 %. The most common benign tumour in this study was giant cell tumour and the most common malignant tumour was osteosarcoma. The most common presenting complaint of all bone lesions was pain (96.7 %) followed by swelling (75.8 %). CONCLUSIONS For precise diagnosis of majority of bone lesions, histopathology is regarded as the gold standard. A multidisciplinary approach (clinical, radiological and histopathological) is required for exact diagnosis of different lesions. KEYWORDS Histopathology, Osteomyelitis, Bone

HISTOPATHOLOGICALANALYSIS OF TUMOURS AND TUMOUR-LIKE LESIONS OF COLON AND RECTUM

2021 ◽  
pp. 9-11
Author(s):  
Durga Nand Jha ◽  
Hari Shankar Mishra ◽  
Ajit Kumar Chaudhary ◽  
Debarshi Jana
Keyword(s):  
Histopathological Examination ◽  
Correct Diagnosis ◽  
Malignant Tumour ◽  
Juvenile Polyp ◽  
Tubular Adenoma ◽  
Malignant Tumours ◽  
Cross Sectional ◽  
Colorectal Biopsies ◽  
Colon And Rectum ◽  
Benign Tumours

Background:Tumours and tumour like lesions of the colon and rectum have overlapping clinical presentation and may be difcult to diagnose on clinical grounds alone. Histopathological examination although helpful to arrive at correct diagnosis, at times may be difcult and may require ancillary tests such as immunohistochemistry. Materials and Methods: A prospective cross sectional study enrolled 125 cases of colorectal biopsies after histopathological conrmation of tumours and tumour like lesions. The specimens were received at the Department of Pathology, DMCH, Laheriasarai, Bihar from December 2019 to November 2020. Results: Out of 125 cases, 32 cases were benign tumours, 36 cases were malignant tumours and 57 cases were tumour like lesions. Most common age range was 51-60 years with mean age of 38 years. Males comprised 76.74% and females 23.26% with ratio of 3:1. Juvenile polyp was the commonest lesion. Among benign tumours, tubular adenoma was the most common (19.2%), adenocarcinoma was most common malignant tumour (25.6%) and juvenile polyp was the most common tumour like lesion (27.2%). Left side was most common side (66.67%) and rectum was the most common site (48.8%). Conclusions: The commonest indications for colorectal biopsies were tumours and tumour like lesions. Juvenile polyp was the most common tumour like lesion, tubular adenoma was the most common benign tumour and adenocarcinoma was the most common malignant tumour. Histopathological examination is a gold standard for conrmation of all tumour and tumours like lesions of colon and rectum.

scholarly journals Histopathological analysis of tumours and tumour-like lesions of colon and rectum

2020 ◽  
Vol 10 (1) ◽  
pp. 1654-1658
Author(s):  
Pramila Vaidhya ◽  
Ram Chandra Adhikari ◽  
Anil Dev Pant
Keyword(s):  
Histopathological Examination ◽  
Correct Diagnosis ◽  
Malignant Tumour ◽  
Juvenile Polyp ◽  
Histopathological Analysis ◽  
Tubular Adenoma ◽  
Malignant Tumours ◽  
Colorectal Biopsies ◽  
Colon And Rectum ◽  
Benign Tumours

Background: Tumours and tumour like lesions of the colon and rectum have overlapping clinical presentation and may be difficult to diagnose on clinical grounds alone. Histopathological examination although helpful to arrive at correct diagnosis, at times may be difficult and may require ancillary tests such as immunohistochemistry. Materials and Methods: A prospective cross sectional study enrolled 125 cases of colorectal biopsies after histopathological confirmation of tumours and tumour like lesions. The specimens were received at the Department of Pathology, of TUTH, from December 1, 2015 to November 30, 2016. Results: Out of 125 cases, 32 cases were benign tumours, 36 cases were malignant tumours and 57 cases were tumour like lesions. Most common age range was 51-60 years with mean age of 38 years. Males comprised 76.74% and females 23.26% with ratio of 3:1. Juvenile polyp was the commonest lesion. Among benign tumours, tubular adenoma was the most common (19.2%), adenocarcinoma was most common malignant tumour (25.6%) and juvenile polyp was the most common tumour like lesion (27.2%). Left side was most common side (66.67%) and rectum was the most common site (48.8%). Conclusions: The commonest indications for colorectal biopsies were tumours and tumour like lesions. Juvenile polyp was the most common tumour like lesion, tubular adenoma was the most common benign tumour and adenocarcinoma was the most common malignant tumour. Histopathological examination is a gold standard for confirmation of all tumour and tumours like lesions of colon and rectum.

scholarly journals Struma Ovarii - A Case Report

KYAMC Journal ◽  
2017 ◽  
Vol 7 (1) ◽  
pp. 734-735
Author(s):  
Md Mahbur Rashid Sarker ◽  
Md Shamim Farooq
Keyword(s):  
Histopathological Examination ◽  
Ovarian Tissue ◽  
Thyroid Tissue ◽  
Excision Biopsy ◽  
Struma Ovarii ◽  
Malignant Tumours ◽  
Rare Form ◽  
Neoplastic Lesion ◽  
Diagnostic Key ◽  
Benign Tumours

Struma ovarii (literally: goitre of the ovary) is a rare form of monodermal teratoma that contains mostly thyroid tissue. The vast majority are benign tumours; however, malignant tumours of this type is found in a small percentage of cases. It is most common between the ages of 40 and 60 years and accounts for approximately 5 percent of all ovarian teratomas. Here we present a case of left sided struma ovarii. This patient is a 39 years' woman from Bhobanipur, Rajbari, Bangladesh. She noticed bleeding per vagina, abdominal swelling and left pelvic region mass for few months. Clinical & imaging examination revealed ascites and left ovarian neoplastic lesion. After excision biopsy, histopathological examination was performed. Microscopically, it shows ovarian tissue but predominantly composed of mature thyroid tissue which are diagnostic key feature of struma ovarii.KYAMC Journal Vol. 7, No.-1, Jul 2016, Page 734-735

Histopathological Study of Lesions of the Nasal Cavity, Paranasal Sinuses and Nasopharynx in a Tertiary Care Centre, Visakhapatnam over a Period of 2 Years

2021 ◽  
Vol 8 (33) ◽  
pp. 3054-3059
Author(s):  
Rajendra Prasad Jagannadham ◽  
Lakshmi Latchupatula ◽  
Sravani Ponnada ◽  
Neelima Lalam ◽  
Raghunadhababu Gudipudi ◽  
...  
Keyword(s):  
Nasal Cavity ◽  
Paranasal Sinuses ◽  
Histopathological Examination ◽  
Tertiary Care ◽  
Histopathological Study ◽  
Histopathological Diagnosis ◽  
Malignant Tumours ◽  
Tertiary Care Centre ◽  
Female Ratio ◽  
Male Predominance

BACKGROUND A variety of non - neoplastic and neoplastic conditions involve the nasal cavity, paranasal sinuses and nasopharynx and these are very common lesions encountered in clinical practice. Histopathological examination of these lesions is the gold standard for diagnosis because management and prognosis vary among different lesions. The aim of the present study was to evaluate the histopathological study of the lesions of the nasal cavity, paranasal sinuses and nasopharynx in relation to their incidence, age, gender and site wise distribution and to compare the results with the available data. METHODS A study of 88 cases was conducted for a period of 2 years from August 2017 to July 2019. After fixation, Processing and Haematoxylin and Eosin staining and special stains histopathological diagnosis was made. RESULTS Among 88 total cases, 58 were males and 30 were females. A male predominance was observed with a male to female ratio of 1.93 : 1. They were more common in third, fourth and fifth decade of life. Malignant nasal lesions were seen after fourth decade of life. Nasal lesions were more common in nasal cavity (67.05 %), followed by paranasal sinuses (18.18 %) and nasopharynx (14.75). Out of 88 total cases, 39 (44.32 %) were non - neoplastic, 30 (34.09 %) were benign and 19 (21.59 %) were malignant nasal lesions. CONCLUSIONS Sinonasal lesions and nasopharyngeal lesions can have various differential diagnoses. A complete clinical, radiological and histopathological correlation helps to categorize these sinonasal lesions into various non - neoplastic and neoplastic types. But histopathological examination remains the mainstay of definitive diagnosis. KEYWORDS Nasal Cavity, Paranasal Sinuses, Nasopharynx, Benign Tumours, Malignant Tumours, Histopathological Examination

scholarly journals Clinicopathological study of sinonasal masses

1970 ◽  
Vol 16 (1) ◽  
pp. 15-22 ◽  
Author(s):  
Abu HenaMohammad Parvez Humayun ◽  
AHM Zahurul Huq ◽  
SM Tarequddin Ahmed ◽  
Md Shah Kamal ◽  
Kyaw Khin U ◽  
...  
Keyword(s):  
Histopathological Examination ◽  
Malignant Lesion ◽  
Malignant Tumour ◽  
Neck Surgery ◽  
Female Ratio ◽  
Medical College ◽  
Male To Female ◽  
Study Setting ◽  
Head Neck Surgery ◽  
Head Neck

Objective: To observe the incidence, clinical presentation and to perform comparative studyof different sinonasal masses. Study design: Prospective study. Setting: Department ofotolaryngology and Head-Neck Surgery & ENT OPD of Chittagong Medical College Hospital.Patients & methods: 50 patients are included in this study (39 male & 11 female) between theages of 3 years and 80 years who were treated between August 2006 to January 2007. Studybased on history, clinical, radiological, laboratory and histopathological examination. Results:Mean age for male was 35.12 years and for female was 22.63 years. Male to female ratio was3.5:1. Highest frequency was noted in second decade. Most of patient (78%) were from poorclass. Frequency of inflammatory nasal masses were more in second decade, benign tumourin fourth and fifth decade, malignant tumour in second decade (OAN & NHL) and fifth andsecond decades (others). Rhinosporidiosis were most frequent inflammatory nasal masses.Nasal obstruction was the commonest and orbitus symptoms were less frequent symptoms.But orbital symptoms were more prevalent in malignant lesion. Conclusion: sinonasal massesare found in all age group. Rhinosporidiosis are appearing to be the commonest nasal masses.The prevalence of nasal polyp is also high. Among the malignant sinonasal masses thepercentage of squamous cell carcinoma is high.DOI: 10.3329/bjo.v16i1.5776Bangladesh J Otorhinolaryngol 2010; 16(1): 15-22

scholarly journals A histopathological review of nephrectomy specimens with an emphasis on pathological assessment of prognostic indicators in malignant lesions

Biomedicine ◽  
2021 ◽  
Vol 40 (4) ◽  
pp. 492-501
Author(s):  
Shubha P. Bhat ◽  
Krishna Prasad H.V. ◽  
Rajeev T.P. ◽  
Kishan Prasad H.L. ◽  
Teerthanath Srinivas ◽  
...  
Keyword(s):  
Histopathological Examination ◽  
Malignant Tumour ◽  
Prognostic Indicators ◽  
Wilms Tumour ◽  
Malignant Tumours ◽  
Neoplastic Lesions ◽  
Kidney Lesion ◽  
Microscopic Features ◽  
Malignant Lesions ◽  
Pathological Assessment

Introduction and Aim: Various non-neoplastic and neoplastic lesions occur in the kidney. Pathological assessment of gross and microscopic features in nephrectomy specimens is essential for diagnosis and predicts the prognosis in malignant tumours. Materials and Methods: Case records of 46 nephrectomy specimens received between two-year periods were retrieved. Detailed gross and histopathological and immunohistochemical features were studied, and malignant tumours were analysed using CAP protocol. Results: Out of 46 nephrectomy specimens, 17 were non-neoplastic and 29 neoplastic. Males constituted 32 cases and females 14 cases. The commonest non-neoplastic kidney lesion was chronic pyelonephritis with hydronephrosis (29%). The mixed epithelial and stromal tumour was the frequently encountered benign tumour (50%). Renal cell carcinoma was the most common malignant tumour in adults (70%) and Wilms tumour in children (4%). Conclusion: Histopathological examination of nephrectomy specimens helps in diagnosing, staging, and planning the management.

scholarly journals Cytohistopathological Study of Salivary Gland Lesions in Bundelkhand Region, Uttar Pradesh, India

2014 ◽  
Vol 2014 ◽  
pp. 1-5 ◽  
Author(s):  
Anita Omhare ◽  
Sanjeev Kumar Singh ◽  
Jitendra Singh Nigam ◽  
Ankit Sharma
Keyword(s):  
Salivary Gland ◽  
Low Cost ◽  
Uttar Pradesh ◽  
Diagnostic Technique ◽  
High Specificity ◽  
Turnaround Time ◽  
Malignant Tumours ◽  
Female Ratio ◽  
Specificity And Sensitivity ◽  
Benign Tumours

Background. FNAC is a useful method for evaluating suspicious salivary glands lesions due to its low cost, minimum morbidity, rapid turnaround time, high specificity, and sensitivity. Aim. To know the frequency of the salivary gland lesions and cytohistological correlation in the Jhansi region, Uttar Pradesh, India. Material and Methods. In present study 124 cases were included and cytohistological correlation was made in 86 cases only. FNA was performed by using a 23/24-gauge needle without local anaesthesia. Air dried and 95% ethyl alcohol fixed wet smears were stained with Giemsa stain and Papanicolaou stain, respectively. Paraffin embedded tissue sections were stained with Haematoxylin and Eosin. Results. Parotid gland was the most commonly involved salivary gland. The commonest age group was 20 to 29 years, 30 to 39 years, and 60 to 69 years for nonneoplastic lesions, benign tumours, and malignant tumours, respectively. The overall male to female ratio was 1.17 : 1. The diagnostic accuracy of FNAC was 100%, 93.3%, and 88.2% for nonneoplastic lesions, benign tumours, and malignant tumours, respectively. Conclusion. The high accuracy, sensitivity, and specificity of FNAC confirm that preoperative cytology is a useful, quick, reliable diagnostic technique for rapid diagnosis and suitable for developing countries.

Histopathological Profile of Non-Haematological Paediatric Neoplasms in Hadoti Region of Rajasthan

2020 ◽  
Vol 7 (43) ◽  
pp. 2453-2457
Author(s):  
Praveen Kumar Bairwa ◽  
Neelu Vashist ◽  
Deepti Sukheeja
Keyword(s):  
Epidemiological Data ◽  
Developed Countries ◽  
Bone Tumours ◽  
Age Group ◽  
Malignant Tumours ◽  
Female Ratio ◽  
Paediatric Tumours ◽  
Haematological Neoplasms ◽  
Benign Tumours ◽  
Male To Female

BACKGROUND Malignancy is a major cause of childhood death in developed countries. In developing countries like India, paediatric tumours are rising day by day. Proper management of paediatric tumours needs epidemiological data in various geographical areas. The present study was carried out to classify and find out the histopathological profile of solid tumours of childhood and infancy in 0 - 14 years age group from 1st January 2015 to 31st December 2017. METHODS We studied histopathology reports of 173 paediatric tumours over a period of 3 years. All the biopsy cases of solid neoplasms in the age group 0 - 14 years were included. RESULTS In our study of 173 paediatric tumours, 133 (76.87 %) were benign and 40 (23.12 %) were malignant. Maximum incidence of malignant paediatric tumours was seen in the age group of 0 - 14 years [12.13 % (21 out of 173)], with male to female ratio of (1:1.3). Amongst the benign tumours, vascular tumours were most common [27.74 % (48 of 173 cases)], with highest incidence of haemangioma [68.75 % (33 of 48 cases)]. Amongst the malignant tumours, most common were bone tumours [6.35 % (11 of 173 cases)] and amongst bone tumours, Ewing’s sarcoma accounted for 63.63 % cases (7 of 11 cases). CONCLUSIONS The incidence of paediatric neoplasms in Hadoti region of Rajasthan is 0.75 % and the majority (54.33 %) of neoplasms occurred in 10 - 14 yrs. age group. KEYWORDS Histopathology, Paediatric, Non-Haematological Neoplasms

scholarly journals Spectrum of primary salivary gland tumors with special emphasis on their management and outcome at a rural tertiary care centre

2020 ◽  
Vol 7 (3) ◽  
pp. 818
Author(s):  
Dwaipayan Samaddar ◽  
Jaya B. Samaddar ◽  
Ahmad M. Aziz
Keyword(s):  
Salivary Gland ◽  
Tertiary Care ◽  
Study Data ◽  
Salivary Gland Tumors ◽  
P Value ◽  
Malignant Tumours ◽  
Tertiary Care Centre ◽  
Female Ratio ◽  
Medical College ◽  
Benign Tumours

Background: Salivary gland tumors (SGT) are uncommon tumors of diverse histopathology accounting for <2% of all neoplasms. Early diagnosis differentiates between benign and malignant SGT and less extensive surgical procedure can be performed. The objective is to study the spectrum of primary SGT with special emphasis on their distribution, treatment and outcome at a rural tertiary care centre.Methods: A prospective observational study was conducted on 30 consecutive primary SGT patients attending the Departments of Surgery and Otorhinolaryngology of North Bengal Medical College and Hospital over a period of one and half years. All patients were clinically evaluated, investigated, treated accordingly and followed up during the period of study. Data was collected and compiled in Excel sheet and analysed using GraphPad Software and GraphPad QuickCalcs 2018 (San Diego, CA). A p value <0.05 was considered statistically significant.Results: Maximum patients (83.3%) were in the age range of 31-60 years. The male to female ratio was 1:4 for benign tumours and 1:1 for malignant tumours. Malignant cases were 66.67%. Involvement of parotid gland was the commonest (43.3%) and mostly presented with swelling (73.3%). Pleomorphic salivary adenoma was the commonest benign tumor (33.3%) and mucoepidermoid carcinoma was the commonest malignant tumor (16.7%). Permanent facial palsy was observed in 2 (9.5%) and recurrence in 4 patients (19%).Conclusions: SGT are rare and present in various modes. Malignant cases were singularly more in this study.

scholarly journals Workplace eye safety: a neglected essential

2020 ◽  
Vol 7 (11) ◽  
pp. 4518
Author(s):  
Aastha N. Patel ◽  
Shankar S. Ganvit
Keyword(s):  
Significant Proportion ◽  
Working Hours ◽  
Clinical History ◽  
Significant Loss ◽  
Working Environment ◽  
Age Group ◽  
Female Ratio ◽  
Chemical Hazards ◽  
Detailed Clinical History ◽  
History Of

 Background: An occupational hazard is a hazard experienced in the workplace. This includes many types of hazards like chemical hazards, biological hazards, psychosocial hazards and physical hazards. Occupational ocular trauma holds significant proportion of visual morbidity worldwide. This can be prevented with the use of proper protective eyewear and strict compliance. This survey was conducted to study occupational related ocular hazard in our tertiary health care system hospital having patients involved in various occupations.Methods: A total of 90 occupational ocular injuries were recorded during study period. The age group of the patients to be studied was between 20 to 60 years. Brief history of present complaints, detailed clinical history and occupation history as like type of work, working environment, place, working hours was recorded. Required ophthalmological check-up was done. All valid responses were tabulated and analysed. Appropriate treatment was given.Results: Our study showed that majority (85.6%) of patients were not wearing protective eye equipment. Male to female ratio was approximately 3:1. Major age group affected was between 31-40 years (41.1%). Welders (40%) were more prone to injury occupation wise.Conclusions: Occupational eye injury is often severe and it contributes to significant loss. Incompliance of appropriate protective eye wear can lead to potential eye damage and permanent blindness.

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