Spectrum of primary salivary gland tumors with special emphasis on their management and outcome at a rural tertiary care centre

Background: Salivary gland tumors (SGT) are uncommon tumors of diverse histopathology accounting for <2% of all neoplasms. Early diagnosis differentiates between benign and malignant SGT and less extensive surgical procedure can be performed. The objective is to study the spectrum of primary SGT with special emphasis on their distribution, treatment and outcome at a rural tertiary care centre.Methods: A prospective observational study was conducted on 30 consecutive primary SGT patients attending the Departments of Surgery and Otorhinolaryngology of North Bengal Medical College and Hospital over a period of one and half years. All patients were clinically evaluated, investigated, treated accordingly and followed up during the period of study. Data was collected and compiled in Excel sheet and analysed using GraphPad Software and GraphPad QuickCalcs 2018 (San Diego, CA). A p value <0.05 was considered statistically significant.Results: Maximum patients (83.3%) were in the age range of 31-60 years. The male to female ratio was 1:4 for benign tumours and 1:1 for malignant tumours. Malignant cases were 66.67%. Involvement of parotid gland was the commonest (43.3%) and mostly presented with swelling (73.3%). Pleomorphic salivary adenoma was the commonest benign tumor (33.3%) and mucoepidermoid carcinoma was the commonest malignant tumor (16.7%). Permanent facial palsy was observed in 2 (9.5%) and recurrence in 4 patients (19%).Conclusions: SGT are rare and present in various modes. Malignant cases were singularly more in this study.

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Histopathological Study of Lesions of the Nasal Cavity, Paranasal Sinuses and Nasopharynx in a Tertiary Care Centre, Visakhapatnam over a Period of 2 Years

Journal of Evidence Based Medicine and Healthcare ◽

10.18410/jebmh/2021/557 ◽

2021 ◽

Vol 8 (33) ◽

pp. 3054-3059

Author(s):

Rajendra Prasad Jagannadham ◽

Lakshmi Latchupatula ◽

Sravani Ponnada ◽

Neelima Lalam ◽

Raghunadhababu Gudipudi ◽

...

Keyword(s):

Nasal Cavity ◽

Paranasal Sinuses ◽

Histopathological Examination ◽

Tertiary Care ◽

Histopathological Study ◽

Histopathological Diagnosis ◽

Malignant Tumours ◽

Tertiary Care Centre ◽

Female Ratio ◽

Male Predominance

BACKGROUND A variety of non - neoplastic and neoplastic conditions involve the nasal cavity, paranasal sinuses and nasopharynx and these are very common lesions encountered in clinical practice. Histopathological examination of these lesions is the gold standard for diagnosis because management and prognosis vary among different lesions. The aim of the present study was to evaluate the histopathological study of the lesions of the nasal cavity, paranasal sinuses and nasopharynx in relation to their incidence, age, gender and site wise distribution and to compare the results with the available data. METHODS A study of 88 cases was conducted for a period of 2 years from August 2017 to July 2019. After fixation, Processing and Haematoxylin and Eosin staining and special stains histopathological diagnosis was made. RESULTS Among 88 total cases, 58 were males and 30 were females. A male predominance was observed with a male to female ratio of 1.93 : 1. They were more common in third, fourth and fifth decade of life. Malignant nasal lesions were seen after fourth decade of life. Nasal lesions were more common in nasal cavity (67.05 %), followed by paranasal sinuses (18.18 %) and nasopharynx (14.75). Out of 88 total cases, 39 (44.32 %) were non - neoplastic, 30 (34.09 %) were benign and 19 (21.59 %) were malignant nasal lesions. CONCLUSIONS Sinonasal lesions and nasopharyngeal lesions can have various differential diagnoses. A complete clinical, radiological and histopathological correlation helps to categorize these sinonasal lesions into various non - neoplastic and neoplastic types. But histopathological examination remains the mainstay of definitive diagnosis. KEYWORDS Nasal Cavity, Paranasal Sinuses, Nasopharynx, Benign Tumours, Malignant Tumours, Histopathological Examination

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Comparative assessment of fetomaternal outcome in twin pregnancy with singleton pregnancy at tertiary care centre

International Journal of Reproduction Contraception Obstetrics and Gynecology ◽

10.18203/2320-1770.ijrcog20172319 ◽

2017 ◽

Vol 6 (6) ◽

pp. 2395

Author(s):

Divya Gupta ◽

Premlata Mital ◽

Bhanwar Singh Meena ◽

Devendra Benwal ◽

. Saumya ◽

...

Keyword(s):

Twin Pregnancy ◽

Tertiary Care ◽

Comparative Assessment ◽

P Value ◽

Care Centre ◽

Tertiary Care Centre ◽

Singleton Pregnancy ◽

Medical College ◽

Obstetrics And Gynaecology ◽

Twin Pregnancies

Background: Multiple pregnancy remains one of the highest risk situations for the mother, foetus and neonate despite recent advances in obstetrics, perinatal and neonatal care. Twin pregnancies have increased rates of obstetric and perinatal complications compared to singletons Objective of present study was comparative assessment of fetomaternal outcome in twin pregnancy with singleton pregnancy in Obstetrics and Gynaecology Department of S.M.S. Medical College, Jaipur.Methods: This was a hospital based, prospective observational study done in the Department of Obstetrics and Gynaecology. S.M.S. Medical College, Jaipur from April 2015 to March 2016. 150 women with twin pregnancy and 150 women with singleton pregnancies at gestation age of 28 weeks and above coming for delivery and consented for the study were included in the study. Women with chronic medical disorder or chronic hypertension were excluded from the study. Maternal and neonatal outcome recorded and analysed.Results: Occurrence of twin in our study was 2.82%. Risk of preterm labour was about nine times higher in twin pregnancies than the singleton (OR: 2.74, 95% CI; 1.4494-5.1884, P value 0.001). The risk of premature rupture of membrane was increased by 2.74 times in twin pregnancies (OR:2.74; 95% CI: 1.4494-5.1884, p value .001). There was 3-time increased risk of malpresentation (OR 3.14; CI:1.7184-5.7480, p value .00002) and 2.28 times increase in hypertensive disorder (OR 2.28; 95% CI: 1.0727-4.8823, p value .03) in twin pregnancies. The risk of asphyxia and septicaemia was 2.5 times more in twins.Conclusions: Twin pregnancy is a high-risk pregnancy with more complications in mother and foetus and is a great challenge for obstetrician. So, it should be managed carefully at tertiary care centre to reduce the maternal and perinatal mortality and morbidity.

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Cytohistopathological Study of Salivary Gland Lesions in Bundelkhand Region, Uttar Pradesh, India

Pathology Research International ◽

10.1155/2014/804265 ◽

2014 ◽

Vol 2014 ◽

pp. 1-5 ◽

Cited By ~ 5

Author(s):

Anita Omhare ◽

Sanjeev Kumar Singh ◽

Jitendra Singh Nigam ◽

Ankit Sharma

Keyword(s):

Salivary Gland ◽

Low Cost ◽

Uttar Pradesh ◽

Diagnostic Technique ◽

High Specificity ◽

Turnaround Time ◽

Malignant Tumours ◽

Female Ratio ◽

Specificity And Sensitivity ◽

Benign Tumours

Background. FNAC is a useful method for evaluating suspicious salivary glands lesions due to its low cost, minimum morbidity, rapid turnaround time, high specificity, and sensitivity. Aim. To know the frequency of the salivary gland lesions and cytohistological correlation in the Jhansi region, Uttar Pradesh, India. Material and Methods. In present study 124 cases were included and cytohistological correlation was made in 86 cases only. FNA was performed by using a 23/24-gauge needle without local anaesthesia. Air dried and 95% ethyl alcohol fixed wet smears were stained with Giemsa stain and Papanicolaou stain, respectively. Paraffin embedded tissue sections were stained with Haematoxylin and Eosin. Results. Parotid gland was the most commonly involved salivary gland. The commonest age group was 20 to 29 years, 30 to 39 years, and 60 to 69 years for nonneoplastic lesions, benign tumours, and malignant tumours, respectively. The overall male to female ratio was 1.17 : 1. The diagnostic accuracy of FNAC was 100%, 93.3%, and 88.2% for nonneoplastic lesions, benign tumours, and malignant tumours, respectively. Conclusion. The high accuracy, sensitivity, and specificity of FNAC confirm that preoperative cytology is a useful, quick, reliable diagnostic technique for rapid diagnosis and suitable for developing countries.

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Salivary gland tumours: a retrospective study at a tertiary care centre in South India

International Journal of Otorhinolaryngology and Head and Neck Surgery ◽

10.18203/issn.2454-5929.ijohns20211576 ◽

2021 ◽

Vol 7 (5) ◽

pp. 825

Author(s):

Neha Swarnkar ◽

Srinivasan Venkataraman ◽

Prasanna Kumar Saravanam

Keyword(s):

Salivary Gland ◽

Retrospective Study ◽

Parotid Gland ◽

Pleomorphic Adenoma ◽

South India ◽

Tertiary Care ◽

Salivary Gland Tumors ◽

Care Centre ◽

Tertiary Care Centre ◽

Salivary Gland Tumours

Background: Salivary gland tumors are morphologically and histologically diverse group of lesions and their frequency varies in several parts of the world. Better understanding of these tumours will help in assessing the behaviour and outcomes of lesions of this region. The aim of this study was to analyse the charactertistics of different tumours occurring in the salivary gland in a tertiary care centre in South India.Methods: A retrospective study was conducted of salivary gland tumors diagnosed from the year 2015 to 2020. Patient age and gender, tumor site and frequency, histopathological diagnosis were evaluated and analysed.Results: A total of 36 salivary gland tumor cases was identified, 30 (87.3%) of which were classified as benign and 6 (12.7%) as malignant. Most tumors occurred in the parotid gland (81.3%). Pleomorphic adenoma was the most common tumor in 23 patients (63.8%), followed by warthins tumour. The tumors occurred more often in women than men.Conclusion: The results of the present study reinforce prevalence of salivary gland tumours. The parotid gland is the most common location and pleomorphic adenoma are the most frequent lesions. The malignant tumors also can occur in these glands and good clinical suspicion is necessary.

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A study of serum C peptide levels in newly detected diabetic patients in tertiary care hospital

International Journal of Advances in Medicine ◽

10.18203/2349-3933.ijam20211475 ◽

2021 ◽

Vol 8 (5) ◽

pp. 679

Author(s):

Balakrishna Teli ◽

Prabhu S. ◽

Sneha Biradar

Keyword(s):

Tertiary Care ◽

Cross Sectional Study ◽

Study Data ◽

P Value ◽

Diabetic Patients ◽

Care Hospital ◽

Cross Sectional ◽

C Peptide ◽

Medical College ◽

Endogenous Insulin

Background: Diabetes mellitus (DM) refers to a group of common metabolic disorders that share the phenotype of hyperglycemia. The deficiency of C-peptide in type 1 DM or its excess in type 2 DM leads to the development of disorders which includes the cardiovascular, nervous, excretory and other systems. The present study is done to assess the serum C-peptide levels in newly detected diabetic patients and its significance in classification of diabetes and deciding about management.Methods: This cross sectional study was conducted within the hospitals attached to Bangalore medical college and research institute. 65 newly detected diabetes patients who gave consent for study and satisfy the inclusion criteria were included in the study. Data was collected using semi structured questionnaire, clinical examination and relevant investigations. Statistical analysis was performed using SPSS software. A p value of <0.05 was considered significant.Results: C-peptide levels showed that 34 (52.3%) subjects had C-peptide levels >2 followed by 10 (15.4%) subjects having 0.1 to 0.6, 9 (13.8%) subjects having 1 to 2, 6 (9.2%) subjects each having 0.6 to 1 and <0.1.Conclusions: Serum C-peptide levels are useful as an index of endogenous insulin production. Low C-peptide levels need insulin treatment due to poor insulin reserve. Majority of the subjects, who had low serum C-peptide levels also had low BMI suggesting a positive correlation between C-peptide levels and BMI.

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Thoracic empyema: clinical course and management in Trivandrum Medical College

International Journal of Research in Medical Sciences ◽

10.18203/2320-6012.ijrms20213407 ◽

2021 ◽

Vol 9 (9) ◽

pp. 2681

Author(s):

Sony P. S. ◽

Vinu C. V. ◽

Suresh Kumar J. ◽

Kishore Lal

Keyword(s):

Treatment Guidelines ◽

Early Recognition ◽

Tertiary Care ◽

Community Acquired Pneumonia ◽

Chronic Obstructive ◽

Tertiary Care Centre ◽

Obstructive Pulmonary Disease ◽

Female Ratio ◽

Thoracic Empyema ◽

Medical College

Background: The incidence of empyema thoracis among adults is increasing steadily. It may be primary empyema (pleural infection developing without pneumonia) or secondary empyema. The common cause of secondary empyema being- community acquired pneumonia or hospital acquired pneumonia, empyema due to iatrogenic causes, secondary to trauma etc. With advancement in science and technology, early recognition of empyema in patients with symptoms is now possible. But the treatment guidelines are not unified so that each physician may treat this condition in a different way without referring to higher concerned specialties making it complicated. The objective of this study was to determine the clinical profile of thoracic empyema in Trivandrum Medical College a tertiary care centre in South Kerala.Methods: A total of 56 patients with empyema admitted to Government Medical College, Trivandrum, Kerala in 2018-2019 were reviewed retrospectively. The demographic details, clinical presentation, etiology, microbiological findings, and management were recorded in a planned proforma, and analysis was done.Results: The mean age was 49.1 years with peak incidence seen in 40-60 years of age. The male to female ratio was 4.6:1.0 and right pleura was more involved than left pleura. Risk factors were diabetes mellitus, chronic obstructive pulmonary disease, pulmonary tuberculosis, and smoking. Etiology of thoracic empyema was infective in 78.6% cases and traumatic in 21.4% cases. Only two cultures showed gram positive aerobe, rest of the culture was sterile. Only a few cases resolved with medical management. Decortication was needed for 52 patients (82.1%).Conclusions: A unified protocol need to be formulated and followed up in all centres for the management of empyema before its evolution and thus reducing the incidence of empyema and its associated complications.

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ANAEMIA AND MALARIA: A STUDY FROM MADHYA PRADESH

10.36106/gjra/2102505 ◽

2021 ◽

pp. 74-75

Author(s):

Parag Gupta ◽

Lal Pranay Singh

Keyword(s):

Falciparum Malaria ◽

Vivax Malaria ◽

Health Centre ◽

Tertiary Care ◽

P Value ◽

Mosquito Vector ◽

Care Centre ◽

Tertiary Care Centre ◽

Medical College ◽

History Of

Background: Malaria is common despite interventions directed to mosquito vector control and treatment of symptomatic cases. In areas where malaria is hyperendemic, such as the study area, a high percentage of the population may harbor the Plasmodium parasite in their blood. The current study was planned to assess the prevalence of malaria and anemia. Methods: A total number of 150 cases were studied for a period of 2 years from Aug 2013 to Sept 2015. Haematological parameters of 150 patients, including 100 malaria-infected and 50 non-malaria infected, who were admitted at the rural tertiary care centre with history of fever were analysed. Patients who were diagnosed as malaria were included in the study. Cases were selected from the the rural health centre of Index Medical College. Results: The median of Hb in patients with falciparum malaria (11.5 g/dL) was signicantly lower than those with vivax malaria (11.9 g/dL) and nonmalaria (13.8 g/dL) groups (P value=<0.0001). Thirty Five (35%) of patients with falciparum malaria; Thirty Two (32%) of patients with vivax malaria; and Thirteen (26%) of patients with non-malaria groups had anaemia. Conclusion: Malaria is common in patients of anaemia. The prevalence of both are positively correlated and both are associated with increased morbidi

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Comparison of Accuracy of Gonial Angle of Orthopantomogram and Lateral Cephalogram for Mandibular Measurements among Orthodontic Patients Attending Tertiary Care Dental Hospital in Kathmandu

Orthodontic Journal of Nepal ◽

10.3126/ojn.v10i3.35497 ◽

2020 ◽

Vol 10 (3) ◽

pp. 57-61

Author(s):

Vikash Veer Shrestha ◽

Ansu Piya ◽

Anju Khapung ◽

Prakash Bhattarai

Keyword(s):

Tertiary Care ◽

Study Data ◽

P Value ◽

Facial Skeleton ◽

Lateral Cephalogram ◽

Gonial Angle ◽

Medical College ◽

Lateral Cephalograms ◽

Significant Difference ◽

The Difference

Introduction: Gonial angle is an important parameter of the craniofacial complex which is generally used to evaluate the vertical parameters and symmetry of the facial skeleton. Gonial angle can be measured in both orthopantomogram (OPG) and lateral cephalograms. Due to the superimpositions seen while measuring the bilateral strucuture on lateral cephalograms, reliable measurement of the gonial angle becomes difficult. This study is done to clarify the possible application of orthopantomogram (OPG) for evaluating angular measurement of the mandible specifically gonial angle by comparing with lateral cephalogram. Materials and Method: All the patients (104) being treated from January 2018 to August 2020 in department of Orthodontics in Nepal Medical College were included in the study. Gonial angle measurements were made on lateral cephalograms and orthopantomograms of 104 patients – 54 males and 50 females with mean age of 22.20 ± 3.25 years. Patients aged 15-35 years were included in the study. Data was processed in SPSS version 16.0. Result: Mean Gonial angle in lateral cephalogram was greater than mean gonial angle in OPG and this difference was found to be statistically significant (p-value < 0.05). The difference in mean gonial angle was found to be statistically significant when compared between right gonial angle in OPG and gonial angle in lateral cephalogram (p-value < 0.05) and also between left gonial angle in OPG and gonial angle in lateral cephalogram (p-value < 0.05). Conclusion: When gonial angle values obtained from both sides of OPG were compared, no statistically significant difference was found. Significant differences were found when gonial angle values obtained from OPG right and left sides were compared with that of lateral cephalogram.

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CLINICO-EPIDEMIOLOGICAL STUDY OF LEPROSY IN TERTIARY CARE INSTITUTE IN CHHATTISGARH

10.36106/ijar/1503209 ◽

2021 ◽

pp. 7-9

Author(s):

Rakesh Kumar Patel ◽

Akhilesh Behra ◽

Dilip Kumar Sa

Keyword(s):

Tertiary Care ◽

Study Data ◽

Major Health Problem ◽

Female Ratio ◽

Major Health ◽

Medical College ◽

Care Institute ◽

Peripheral Nerve Involvement ◽

Epidemiological Pattern ◽

Male To Female

INTRODUCTION – Leprosy is a chronic bacterial infection. India has achieved an elimination target of less than one case per ten thousand population in December 2005. Even after elimination leprosy is remaining a major health issue in a few states like Chhattisgarh and union territories like Dadra and Nagar haveli. AIMS AND OBJECTIVE –To study the clinico-epidemiological pattern of leprosy in a tertiary care institute at Chhattisgarh. MATERIAL AND METHOD- A retrospective descriptive study was performed at LSLAM medical college, Raigarh, Chhattisgarh. All the cases of leprosy attending skin OPD from January 2020 to December 2020 were recruited for the study. Data was collected in MS excel sheet and analyzed using SPSS software version 20. RESULT – A total of 92 patients were diagnosed as leprosy. 4 (4.35%) patients were children less than 14 years of age. 67 patients were male and 25 were female with male to female ratio was 2.68:1. Commonest age group of presentation was 21 to 40 years. The most common type of leprosy was Borderline Tuberculoid Hansen Disease (BTHD) (43.48%). 64 patients (69.57%) were diagnosed as multibacillary (MB) leprosy. The most common nerve found thickened was ulnar nerve. 30 patients (32.60%) presented with lepra reaction at the time of diagnosis. Out of 30 Lepra reaction cases, 21 (70%) were diagnosed as type1 lepra reaction and the rest 9 (30%) cases were diagnosed as type 2 lepra reaction cases. 59 patients (64.13%) presented with peripheral nerve involvement at the time of diagnosis. 23 (25%) patients were having grade 2 disability at the time of diagnosis. CONCLUSION – Even after achieving the target of elimination leprosy remains a major health problem especially in endemic states of India like Chhattisgarh.

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LRINEC: an economical diagnostic tool for prognosis in patients with necrotizing soft tissue infections in a tertiary care centre

International Surgery Journal ◽

10.18203/2349-2902.isj20192282 ◽

2019 ◽

Vol 6 (6) ◽

pp. 2007

Author(s):

Ballapalli Hari Prasad ◽

Minchala Chengalrayan Narendra ◽

Shaik Nurul Hameed

Keyword(s):

Soft Tissue ◽

Tertiary Care ◽

Lower Limbs ◽

Soft Tissue Infections ◽

Tertiary Care Centre ◽

Female Ratio ◽

Medical College ◽

Necrotizing Soft Tissue Infections ◽

Lrinec Score ◽

A Prospective Study

Background: The objective of the study was to evaluate the efficacy of LRINEC score in the management and prognosis of patients with soft tissue necrotizing infections.Methods: This is a prospective study conducted in Sri Padmavathi Medical College (W), Tirupati, Andhra Pradesh, India from May 2018 to January 2019. It included 50 patients who were diagnosed with severe soft tissue infection of lower limbs who needed surgical intervention. The effectiveness of LRINEC score was determined from the outcome.Results: Age group varied from 40 to 60 years. Out of 50 patients 40 were men and 10 were women. The male to female ratio was 4:1. All the patients were investigated at the time of admission in the emergency department using the LRINEC score. Hospital stay varied from 15-45 days.Conclusions: This study concludes that LRINEC score is an economical and accurate investigating tool in necrotizing soft tissue infections to determine the prognosis and outcomes.

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