Histopathological Study of Myometrial Lesions of Uterus in a Tertiary Care Hospital of South India

2021 ◽  
Vol 8 (06) ◽  
pp. 293-297
Author(s):  
Gayathri B.N ◽  
Mallikarjun A. Pattanashetti ◽  
Priyadarshini M.M
Keyword(s):  
Histopathological Examination ◽  
Tertiary Care ◽  
Abnormal Uterine Bleeding ◽  
Cross Sectional Study ◽  
Histopathological Study ◽  
Care Hospital ◽  
Age Group ◽  
Cross Sectional ◽  
Microscopic Pathology ◽  
Age Range

BACKGROUND The most commonly done gynaecological surgery worldwide is hysterectomy. Myometrial lesions contribute to majority of cases with abnormal uterine bleeding. Leiomyoma and adenomyosis are most common lesions seen in the myometrium. The present study was undertaken to identify the various types of myometrial pathologies in hysterectomy samples. METHODS This is a two-year retrospective cross-sectional study done from January 2017 to December 2018, in the Department of Pathology, Kodagu Institute of Medical Sciences, Madikeri. All the patients who underwent hysterectomy and myomectomy for myometrial lesions of uterus were included in the study. Hysterectomy specimens showing secondaries, gross infection, massive haemorrhage and necrosis were excluded from the study. Gross appearance and microscopic pathology were noted and results were analysed. RESULTS In this study, 148 specimens were included. Age range was from 20 years to 65 years. Histopathological examination revealed that 58.25 % of myometrial lesions were present in the age group of 41 to 50 years followed by age group of 31 to 40 years. Histopathological examination done showed the following diagnosis in patients - leiomyoma (85.13 %), adenomyosis (8.79 %) and leiomyoma with adenomyosis (6.08 %). CONCLUSIONS The commonest histopathological lesion in myometrium was leiomyoma (85.13 %) followed by adenomyosis (8.79 %). It is mandatory to examine the hysterectomy specimens adequately to diagnose myometrial lesions. KEYWORDS Myometrium, Leiomyoma, Adenomyosis

HISTOPATHOLOGICAL STUDY OF ENDOMETRIUM IN WOMEN WITH ABNORMAL UTERINE BLEEDING

2021 ◽  
pp. 30-33
Author(s):  
Bhakti D Deshmukh ◽  
Anuradha Malpani ◽  
Alka V Gosavi ◽  
Kalpana R Sulhyan ◽  
Rucha M Pimpalkhute
Keyword(s):  
Histopathological Examination ◽  
Tertiary Care ◽  
Abnormal Uterine Bleeding ◽  
Intraepithelial Neoplasia ◽  
Mucinous Carcinoma ◽  
Uterine Bleeding ◽  
Serous Carcinoma ◽  
Histopathological Study ◽  
Care Hospital ◽  
Age Group

BACKGROUND –Abnormal uterine bleeding (AUB) is dened as a bleeding pattern that differs in frequency, duration and amount from a pattern observed during a normal menstrual cycle. The term dysfunctional uterine bleeding (DUB) is used to describe abnormal uterine bleeding for which no specic cause has been found. AUB is one of the most common gynaecological problems. This study was done to evaluate histological patterns of endometrium in women with abnormal uterine bleeding. AIMS AND OBJECTIVE – To study various histological patterns of endometrium in abnormal uterine bleeding and correlate it with age, parity and symptoms. MATERIAL AND METHODS –This is a retrospective study, conducted in the Department of Pathology, in a tertiary care hospital from 1st July 2016 to 30th June 2019. Total 718 specimens with AUB were included in the study from the age group of 21 to 95 years. The specimens received were hysterectomy (74.65 %), endometrial biopsies (21.45%), dilatation and curettage (2.79 %) and transcervical resection of endometrium (1.11 %). RESULTS –The patients with AUB were mainly from the age group 41-50 years with menorrhagia as the chief complaint. Most of the women with AUB were multiparous (84.54%). The most common pattern observed on histopathological examination was proliferative endometrium (49.86%) followed by atrophic endometrium (10.31%). Malignancy was found in 2.23% (Endometrioid carcinoma – 1.81%, serous carcinoma - 0.14% and mucinous carcinoma – 0.28%). Endometrial hyperplasia without atypia (23 cases, 3.20%) was more common than endometrial atypical hyperplasia (EAH) / endometrioid intraepithelial neoplasia {EIN} (4 cases, 0.56 %). Various other patterns of endometrium on histopathology were endometritis (6.82 %) followed by endometrial polyp (4.46 %). CONCLUSION – Histopathological examination of endometrium should be done generously in women presenting with abnormal uterine bleeding especially after the age of 40 years to rule out malignant pathology.

scholarly journals Women with Abnormal Endometrial Pathology: Experienced at a Tertiary Care Hospital in Bangladesh

2013 ◽  
Vol 5 (1) ◽  
pp. 11-13
Author(s):  
Mst Syeeda Showkat ◽  
Lubna Khondker ◽  
Shahryar Nabi ◽  
Bishwajit Bhowmik
Keyword(s):  
Endometrial Hyperplasia ◽  
Histopathological Examination ◽  
Tertiary Care ◽  
Cross Sectional Study ◽  
Transvaginal Sonography ◽  
Common Disease ◽  
Care Hospital ◽  
Cross Sectional ◽  
Examination Result ◽  
Endometrial Pathology

Background: Transvaginal sonography is superior to transabdominal sonography in most cases of pelvic pathology. Objective: This study was undertaken to see the clinicalpathological characteristics of endometrial hyperplasia. Methodology: This cross sectional study was carried out from January 2007 to December 2008 for a period of two years. All suspected cases of endometrial hyperplasia were included for this study. Transvaginal sonography (TVS) performed and confirmation was done by histopathological examination. Result: A total number of 40 cases were enrolled for this study. The most common diagnosed endometrial pathology was endometrial hyperplasia which was 42.5% cases. Endometrial polyp was diagnosed in 32.5% cases. Endometrial carcinoma was in 7.5% patients and submucosal fibroid was in 10.0%. Conclusion: Endometrial hyperplasia is the most common disease among the women presented with endometrial pathology. DOI: http://dx.doi.org/10.3329/jssmc.v5i1.16198 J Shaheed Suhrawardy Med Coll, 2013;5(1):11-13

COVID-19: An Experience from a Tertiary Care Hospital of Nowshera

2020 ◽  
Vol 24 (2) ◽  
pp. 149-155
Author(s):  
Hamzullah Khan ◽  
Mohammad Zahid Khan ◽  
Mian Mohammad Naveed
Keyword(s):  
Tertiary Care ◽  
Relevant Information ◽  
Cross Sectional Study ◽  
Care Hospital ◽  
Cross Sectional ◽  
Number Of Patients ◽  
Epidemic Area ◽  
History Of ◽  
Severity Of The Disease ◽  
Age Range

Objective: To determine the frequency of COVID-19 and characteristics of patients presenting to the COVID-19 clinic at Qazi Hussain Ahmed Medical Complex (QHAMC) Nowshera. Methodology: This cross-sectional study was conducted from 21st Feb 2019 to April 8, 2020, in QHAMC Nowshera. Relevant information was collected on a pre-designed Performa prepared following the objectives of the study. Results: Out of 220 patients, 165(75%) were males, and 55(25%) females. 96(43.6%) of the patients were in the age range 18-30 years followed by 52(23.6%) in age range 31-45years and 17(7.7%) with age>60 years etc. Out of total the nasopharyngeal swabs of 26(11.6%) strong suspects were sent for PCR testing. 208(94.5%) were sent home while 12(5.5%) were advised quarantine. Forty-seven (21.4%) had a travel history to an epidemic area in the last 14 days. 51(23.2%) had a positive history of contact. Eighty-five (38.6%) had a fever and sore throat followed by 27(12.3%) with (fever & cough), 24(10.9%) with (cough and shortness of breath/dyspnea) and 14(6.4%) with a simple flue, etc. Out of 26 cases, 6(2.7%) were COVID-19 Positive, 12(5.5%) were negative and results of 8(3.6%) were still awaited. The PCR repeated the test for confirmed cases showed;  4(1.8%) negative, one died and one was refractory positive.  A positive correlation (p=0.03, r=0.4) of an increase in age with the severity of the disease/outcome was recorded. Conclusion: The frequency of infectivity with COVID-19 was 2.6%. A higher number of patients with mild symptoms attend the COVID clinic. The rate of infection and mortality was higher in age> 60 years.

scholarly journals A study of surgical profile of patients with hemorrhoids at a tertiary care hospital

2019 ◽  
Vol 6 (3) ◽  
pp. 916
Author(s):  
Prashant R. Shinde ◽  
Meghraj J. Chawada ◽  
Sudhir B. Deshmukh
Keyword(s):  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Vegetarian Diet ◽  
Cross Sectional Study ◽  
Care Hospital ◽  
Age Group ◽  
Cross Sectional ◽  
Normal Limits ◽  
Skin Tag ◽  
One Year

Background: In hemorrhoids, the anal canal venous plexuses become engorged. It can lead to bleeding, thrombosis, prolapse, pain. Study of surgical profile helps to educate the patients to take proper precautions to avoid the severe forms of it. The objective of the study was to study the surgical profile of patients with hemorrhoids at a tertiary care hospital.Methods: Present study was hospital based cross sectional study. It was carried out at a tertiary care hospital in the department of general surgery among 100 patients who presented with symptoms suggestive of hemorrhoids during the study period from 1st January 2017 to 31st October 2018.Results: Majority of the patients 41% were in the age group of 35-45 years. The number affected by hemorrhoids was more in males i.e. 56%. Incidence of hemorrhoids was more in upper class. Incidence of hemorrhoids was less i.e. 21% among those who took only vegetarian diet. Majority of the patients (78%) presented after one year of occurrence of treatment. 54% of the patients had third grade of hemorrhoids. Bleeding was present in the majority i.e. 98% of the patients. On anorectal examination, it was found that 44% of the patients had fissure and 23% of the patients had peri anal skin tag. Anorectal examination was within normal limits in 33% of the cases.Conclusions: Vegetarian diet may be protective against hemorrhoids. Bleeding was the most common presenting symptom. Thus, study helped to identify that being male, younger age group, non-veg diet may be the risk factors for hemorrhoids.

scholarly journals Cervical Cancer Screening On 1000 Healthy Asymptomatic Women Residing In Slum of Rajshahi City of Bangladesh

2017 ◽  
Vol 7 (1) ◽  
pp. 14-17
Author(s):  
Munira Ferdausi ◽  
Fatema Ashraf ◽  
Nourin Rahman ◽  
Zara Rahman ◽  
Fahima Mustanzid
Keyword(s):  
Tertiary Care Hospital ◽  
Histopathological Examination ◽  
Cervical Screening ◽  
Tertiary Care ◽  
Cross Sectional Study ◽  
Care Hospital ◽  
Cross Sectional ◽  
Study Population ◽  
Asymptomatic Women ◽  
Rajshahi City

Background: Cervical carcinoma is an important cause of mortality among adult women.Objective: The purpose of the present study was to detect the pre-cancerous condition of cervix in women.Methodology: This cross sectional study was carried out in the OPD of a tertiary care hospital of Rajshahi City in Bangladesh during the year June 2010 to August 2011. Healthy asymptomatic women residing in slum of Rajshahi city with a marital age of 8 years and above were included as study population. VIA test was performed in all women. The VIA positive cases were invited for colposcopy and directed biopsies were obtained from women who were colposcopically positive.Result: A total number of 1000 women were studied. Among them 80(8%) women were VIA positive. These positive cases were also referred for colposcopy. Out of the 80 cases, 26 (32%) were colposcopically normal and 50(63%) were CIN-1 and 4(5%) women were CIN II. Directed biopsy was done among colposcopically positive group. Histopathological examination shows 44 (82%) were CIN-1 and 4(7%) were CIN- II and 6(11%) were chronic cervicities.Conclusion: Cervical screening of the slum area women shows an important number of women suffering from precancerous condition of which CIN-l is the most common.J Shaheed Suhrawardy Med Coll, 2015; 7(1):14-17

A STUDY ON SOCIODEMOGRAPHIC PROFILE OF PATIENTS OF INTESTINA OBSTRUCTION IN DR. SUSHEELA TIWARI GOVERNMENT HOSPITAL, HALDWANI

2021 ◽  
pp. 4-6
Author(s):  
Prateek Shakya ◽  
Rajeev Kumar Singh ◽  
Deepak Goyal
Keyword(s):  
Intestinal Obstruction ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Abdominal Tuberculosis ◽  
Cross Sectional Study ◽  
Care Hospital ◽  
Age Group ◽  
Government Hospital ◽  
Cross Sectional ◽  
Sociodemographic Profile

Background/Aim: This study was aimed to provide a sociodemographic prole of intestinal obstruction in a tertiary care hospital in Kumaun region of Uttarakhand, India. Materials and Methods: This was a cross-sectional study of patients admitted in our hospital with a diagnosis of intestinal obstruction between the years 2019 and 2020 at Dr. Susheela Tiwari Government Hospital, Haldwani, Uttarakhand. The study comprised of 250 patients. Results: The commonest age group affected was 18-30 years. In our patients, the main cause of obstruction was adhesions followed by abdominal tuberculosis with MALIGNANCY coming third. Conservative management was advocated in 72 patients while the rest underwent surgery. Conclusion: Adhesion was the main etiology in Intestinal Obstruction. The odds of malignant bowel obstruction are increasing in the proportion of Intestinal Obstruction. There were some differences towards the etiologic spectrum compared with western countries.

scholarly journals Histopathological Study of Post-Surgical Gallbladder to Establish True Histopathology Proven Chronic Inflammation

2021 ◽  
Vol 8 (3) ◽  
pp. 15-19
Author(s):  
Tania Khattak ◽  
Almas Khattak ◽  
Susan Kakakhel ◽  
Anwar Ul Haque
Keyword(s):  
Chronic Inflammation ◽  
Demographic Data ◽  
Descriptive Analysis ◽  
Tertiary Care ◽  
Cross Sectional Study ◽  
Chronic Cholecystitis ◽  
Histopathological Study ◽  
Care Hospital ◽  
Histopathological Changes ◽  
Cross Sectional

OBJECTIVES: The aim of this study was to establish true histopathology proven diagnosis of chronic cholecystitis. METHODOLOGY: A cross-sectional study was conducted on 51 post-surgical gallbladders was done to assess their histopathological patterns in a single centered tertiary care hospital. The specimens were studied for chronic cholecystitis, fibrosis, hypertrophy and presence of Rokitansky-Aschoff sinuses. Descriptive analysis was done and associations of the histopathological changes with demographic data of patients were analyzed through Chi-squared test. RESULTS: Fifty-one post cholecystectomy samples of gallbladder were analyzed for histopathological changes with 82.4% showing chronic cholecystitis, 84.3% fibrosis, 64.7% congestion, and more than 60% mild or moderate hypertrophy. Moreover, 49% of the specimens showed Rokitansky-Aschoff sinuses. All these changes suggest chronic inflammation. CONCLUSION: Chronic cholecystitis, fibrosis, and Rokitansky-Aschoff sinuses are the most common histopathological findings in specimens of patients undergone cholecystectomy for cholelithiasis.  

scholarly journals Dermatological adverse drug reactions in tertiary care hospital: an analysis of causality and severity

2018 ◽  
Vol 7 (8) ◽  
pp. 1620
Author(s):  
Kalpana R. Bharani ◽  
Nitibhushansingh R. Chandel ◽  
Chhaya A. Goyal
Keyword(s):  
Adverse Drug Reactions ◽  
Tertiary Care ◽  
Age Distribution ◽  
Cross Sectional Study ◽  
Care Hospital ◽  
Age Group ◽  
Drug Reactions ◽  
Morphological Pattern ◽  
Cross Sectional ◽  
Moderate Severity

Background: Dermatological adverse drug reactions (ADRs) are easily detected by patients and that precludes further usage of drugs. So, decided to study the pattern, causative drugs, severity of adverse drug reactions and their causality in tertiary care hospital.Methods: It was prospective non inventional cross sectional study. Patients attending OPD or admitted to IPD of all age group and both gender with suspected dermatological ADRs following drug intake were included and the ADRS were recorded on CDSCO’s Pharmacovigilance form. Collected data was analyzed for assessment of causality using WHO-UMC scale, for severity by using Modified Hartwig and Siegel. Morphological pattern, drug groups, gender and age distribution was analyzed.Results: 231 dermatological ADRs were recorded and analyzed. Maximum cases were found in 21-30 years age group (74 cases). Dermatological ADRs were found in 143 females and in 88 males. Three major classes of drugs found responsible for causing dermatological ADRs were -oral Antimicrobials-41 (17.75%) and Injectable Antimicrobials-40 (17.32%), NSAID's-40 (17.32%.) and Topical Betnovate-36 (15.58%.). Regarding the type, 95 cases were of maculopapular rashes (41.12%), steroid damaged face in 42 (18.18%) andacute urticaria in 20 (8.65%). In terms of Severity assessment, authors found 23 cases (9.95%) as Mild, 176 cases (76.19%) of moderate severity and 32 cases (13.85%) of Severe category. In terms of causality assessment: 3 cases as Certain, 68 cases as Probable and 160 cases as Possible.Conclusions: From this study, it was found maximum Dermatological ADRs of moderate severity and few cases of causality category as “Certain”.

scholarly journals Clinico-etiological study of erythroderma cases from tertiary care hospital, Chitradurga, Karnataka, India

2020 ◽  
Vol 6 (4) ◽  
pp. 502
Author(s):  
Harish Gangaraju ◽  
Raghu M. T. ◽  
Yogendra M. ◽  
Virupakshappa H. E. ◽  
Ashwini S. ◽  
...  
Keyword(s):  
Age Of Onset ◽  
Histopathological Examination ◽  
Tertiary Care ◽  
Cross Sectional Study ◽  
Care Hospital ◽  
Drug Induced ◽  
College Hospital ◽  
Cross Sectional ◽  
Female Ratio ◽  
Histopathological Correlation

<p class="abstract"><strong>Background:</strong> Erythroderma is a cutaneous morphological reaction pattern of skin having many underlying causes and finding the etiology helps in the proper management of erythroderma cases.</p><p class="abstract"><strong>Methods:</strong> A cross sectional study was performed at the department of dermatology, Basaveshwara Medical College, Hospital and Research center, Chitradurga. Authors studied 30 consecutive cases of erythroderma from July 2017 to June 2019 with respect to the epidemiological, clinical and histological data. Clinico-histological correlation was analyzed for etiology of erythroderma.<strong></strong></p><p class="abstract"><strong>Results:</strong> The mean age of onset was 35.03 years with a male to female ratio of 3:2. In addition to erythrema and scaling that were present in all patinets, other co-existent features included were pruritus (43.3%), fever (23.3%), and edema (16.7%). Of the pre-existing dermatoses, psoriasis was the most common (36.6%) disease followed by eczema (26.7%), drug-induced erythroderma (16.7%), colloidan baby (3.3%), pityriasisrubrapilaris (3.3%) and in 13.3% of cases, etiology could not be ascertained. Clinico-histopathological correlation could be established in 73.3% of cases.</p><p class="abstract"><strong>Conclusions:</strong> In all erythroderma cases cutaneous features were identical irrespective of etiology. Detailed history, clinico-histopathological examination and other necessary haematological investigations helps to establish the etiology of erythroderma which helps in further management.</p>

scholarly journals Hypocalcemia in Elderly Population in a Tertiary Care Hospital: A Descriptive Cross-sectional Study

2020 ◽  
Vol 58 (231) ◽  
Author(s):  
Sangita Thapa ◽  
Rabindra Jang Rayamajhi
Keyword(s):  
Serum Calcium ◽  
Elderly Population ◽  
Care Center ◽  
Tertiary Care ◽  
Cross Sectional Study ◽  
Care Hospital ◽  
Age Group ◽  
Tertiary Care Center ◽  
Sectional Study ◽  
Cross Sectional

Introduction: As the medical facilities are improving, the life expectancy is increasing which has led to rapid rise in elderly population. The epidemiology of many diseases in elderly has been modified, including calcium imbalance. This study aims to know the prevalence of hypocalcemia in elderly population visiting a tertiary care center of Kathmandu. Methods: A descriptive cross-sectional study was conducted in a tertiary care center of Kathmandu from March to July 2020 after obtaining ethical clearance (Ref: 2003202007). Total 402 participants at or above 60 years of age groups visiting outpatient departments were included in the study by convenience sampling method excluding those under vitamin D and calcium supplements. Serum total calcium level was measured using standard routine method and corrected with albumin. The serum calcium value less than 8 mg/dl was considered as hypocalcemia in accordance with the reference range of our laboratory. Data analysis for calculation of frequency and proportion was done in Statistical Package of Social Sciences. Results: The prevalence of hypocalcaemia in elderly was found to be 97 (24.1%). Out of 286 participants of age group 60-74 years, hypocalcemia was seen in 75 (26.2%) and among 116 participants of age group >74 years, 22 (19%) were hypocalcemic. Among 181 male participants, 44 (24.3%) had hypocalcemia and out of 221 female participants, 53 (24%) had hypocalcemia. Conclusions: The finding of present study suggests that hypocalcemia is common among elderly which can be life threatening. Therefore, regular monitoring of serum calcium is recommended for this age group.

Sign in / Sign up

Export Citation Format

Share Document