scholarly journals Effects of High and Normal Dose Fluid Therapy on Nausea and Vomiting after Pediatric Tonsillectomy: A Comparative Study

2021 ◽  
Author(s):  
Mahshid Nikooseresht ◽  
Pouran Hajian ◽  
Mahshid Shafiian ◽  
Abbas Moradi
Keyword(s):  
Fluid Therapy ◽  
Recovery Room ◽  
Intervention Group ◽  
Perioperative Period ◽  
Nausea And Vomiting ◽  
Control Group ◽  
High Dose ◽  
Normal Dose ◽  
Antiemetic Drugs ◽  
The Difference

Background: Nausea, vomiting, and postoperative pain are common and undesirable complications after anesthesia and tonsillectomy surgery especially in children. This study was designed to evaluate the effects of high and normal dose lactated Ringer infusion on nausea, vomiting, and pain intensity after pediatric tonsillectomy. Methods: A total number of 100 tonsillectomy surgery candidates at the age range of 1-12 years were selected for this randomized clinical trial. The subjects were randomly assigned to the intervention or control group after signing of their informed consent. The intervention group received high-dose fluid therapy (lactated Ringer 30cc/kg) and the control group received the normal dose (lactated Ringer 10cc/kg) during the perioperative period. The amounts of consumed adjuvant antiemetic drugs, incidence of nausea and vomiting, and pain severity were evaluated in both groups in the recovery room, at 12 and 24 hours after tonsillectomy. Results: The incidence of nausea and vomiting and the use of rescue antiemetic drugs in the intervention group compared to the control group, were always lower in the recovery room, 12 and 24 hours after surgery; but only the difference in incidence of nausea and vomiting at 24 hours after surgery was statistically significant (P = 0.027). Conclusion: High-dose fluid therapy significantly reduces the late incidence (24 hours after surgery) of post- tonsillectomy nausea and vomiting in children.

The effect of ear acupressure medicine at the “Shen Men” point on the nausea and vomiting during pregnancy

2021 ◽  
Vol 15 (5) ◽  
pp. 1774-1779
Author(s):  
Sanaz Nehbandani ◽  
Hajar Salehi ◽  
Khadije Rezaie Keikhaie ◽  
Hossein Rashki Ghalenow ◽  
Fatemeh Mirzaie ◽  
...  
Keyword(s):  
Pregnant Women ◽  
Gestational Age ◽  
Intervention Group ◽  
Nausea And Vomiting ◽  
Control Group ◽  
Health Clinics ◽  
Significant Difference ◽  
Quasi Experimental ◽  
The Mean ◽  
The Difference

Introduction & Objective: Nausea and vomiting during pregnancy is one of the most common gastrointestinal disorders that more than 85% of pregnant women experience. However, controlling and treating this complication is still one of the most important issues in antenatal care. Therefore, the aim of this study was to investigate the effect of ear acupressure at Shen Men point on relieving nausea, vomiting and retching during pregnancy. Materials and Methods: In this quasi-experimental study, 100 pregnant women with a gestational age of less than 16 weeks attending the health clinics of Zabol city during 2019-2020 were studied in two control and intervention groups (n = 50 in each group). The samples in the intervention group were trained to apply pressure on their ears’ Shen Men point with the thumb for three minutes three times a day (morning, noon, and night), for a duration of one month. At the end of second and fourth weeks, the data were collected using the Rhodes index form and then, were analyzed by SPSS software version 22. Results: According to the results, there was no significant difference between the two groups in terms of age, gestational age, occupation and education. The difference in the mean scores of nausea, vomiting and retching was not statistically significant between the control and intervention groups before the study. But four weeks after the study, a significant difference was observed in the mean scores of vomiting, nausea and retching between the two groups, so that the mean scores of vomiting, nausea and retching were significantly lower in the intervention group than in the control group. Conclusion: The ear acupressure medicine at the Shen men point can be used as a non-invasive, safe and inexpensive method to relieve nausea, vomiting and retching during pregnancy. Keywords: Acupressure medicine, Shen Men, Vomiting, Pregnancy, Nausea, Retching, Rhodosis

scholarly journals The effect of ear acupressure medicine at the “Shen Men” point on the nausea and vomiting during pregnancy

2021 ◽  
Vol 15 (6) ◽  
pp. 1602-1606
Author(s):  
Sanaz Nehbandani ◽  
Hajar Salehi ◽  
Khadijerezaie Keikhaie ◽  
Hossein Rashki Ghalenow ◽  
Fatemeh Mirzaie ◽  
...  
Keyword(s):  
Pregnant Women ◽  
Gestational Age ◽  
Intervention Group ◽  
Nausea And Vomiting ◽  
Control Group ◽  
Health Clinics ◽  
Significant Difference ◽  
Quasi Experimental ◽  
The Mean ◽  
The Difference

Background: Nausea and vomiting during pregnancy is one of the most common gastrointestinal disorders that more than 85% of pregnant women experience. However, controlling and treating this complication is still one of the most important issues in antenatal care. Aim: To investigate the effect of ear acupressure at Shen Men point on relieving nausea, vomiting and retchingduring pregnancy. Methods: In this quasi-experimental study, 100 pregnant women with a gestational age of less than 16 weeks attending the health clinics ofZabol city during 2019-2020 were studied in two control and intervention groups (n = 50 in each group). The samples in the intervention group weretrained to apply pressure ontheirears’Shen Men point with the thumb for three minutes three times a day (morning, noon, and night), for a duration of one month. At the end of second and fourth weeks, the data were collected using the Rhodes index form and then, were analyzed by SPSS software version 22. Results: According to the results, there was no significant difference between the two groups in terms of age, gestational age, occupation and education. The difference in the mean scores of nausea, vomiting and retching was not statistically significant between the control and intervention groups before the study. But four weeks after the study, a significant difference was observed in the mean scores of vomiting, nausea and retching between the two groups, so that the mean scores of vomiting, nausea and retching were significantly lower in the intervention group than in the control group. Conclusion: The ear acupressure medicine at the Shen men point can be used as a non-invasive, safe and inexpensive method to relieve nausea, vomiting and retching during pregnancy. Keywords :Acupressure medicine, Shen Men, Vomiting, Pregnancy, Nausea, Retching, Rhodosis

The effect of foot reflexology on chemotherapy-induced nausea and vomiting in digestive or lung cancer patients: a randomized controlled trial (Preprint)

2020 ◽  
Author(s):  
Audrey Murat-Ringot ◽  
Pierre Jean Souquet ◽  
Fabien Subtil ◽  
Florent Boutitie ◽  
Marie Preau ◽  
...  
Keyword(s):  
Cancer Patients ◽  
Controlled Trial ◽  
Nausea And Vomiting ◽  
Control Group ◽  
Digestive Cancer ◽  
Complementary Medicines ◽  
Antiemetic Drugs ◽  
Platinum Based Chemotherapy ◽  
Significant Difference ◽  
Delayed Nausea

BACKGROUND Cancer is a chronic disease with an incident worldwide had been 24.5 million and 9.6 million deaths in 2017. Lung and colorectal cancer are the most common cancer for both sexes and according to national and international recommendations platinum-based chemotherapy is the reference adjuvant treatment. This chemotherapy can be moderately to highly emetogenic. Despite antiemetic therapy, chemotherapy-induced nausea and vomiting may persist. Moreover, cancer patient are increasingly interested in alternative and complementary medicines and express the desire that non-pharmacological treatments be used in hospitals. Among alternative and complementary medicines, foot reflexology decreases significantly the severity of chemotherapy-induced nausea and vomiting in breast cancer patients. OBJECTIVE The primary objective of the present study was to assess the benefits of foot reflexology as a complement to conventional treatments on severity of acute chemotherapy-induced nausea and vomiting in digestive or lung cancer patients. The secondary objectives assessed were the frequency and severity of delayed chemotherapy-induced nausea and vomiting, quality of life, anxiety, and self-esteem. METHODS The present study was conducted between April 2018 and April 2020 in French University Hospital. This is an open-label randomized controlled trial. Participants are randomized into two groups: 40 to interventional group (conventional care with foot reflexology) and 40 to control group (conventional care without foot reflexology). Foot reflexology sessions (30 minutes) are performed on an outpatient or inpatient. Eligible participants are patients with a lung or digestive cancer with indication for platinum-based chemotherapy. RESULTS The severity of acute nausea and vomiting was assessed with a visual analogue scale during the second cycle of chemotherapy. A significant increase of at least 2 points was observed for control group (20.6%, P = 0.01). Across all cycle, the foot reflexology group showed a trend towards less frequent delayed nausea (P=0.28), a significantly less frequent consumption of antiemetic drugs (P=0.04), and no significant difference for vomiting (P=0.99); there was a trend towards a perception of stronger severity for delayed nausea in the control group (P=0.39). According to quality of life and anxiety, there was no significant difference between the interventional group and the control group (P=0.32 and P=0.53 respectively). CONCLUSIONS In conclusion, the present study results indicated that foot reflexology decreased significantly the severity of acute nausea and consumption of antiemetic drugs in lung and digestive cancer patients. No side effects from foot reflexology have been noted. In order to better respond to a desire of patients for non-pharmacological treatments and CAMs to be used in hospitals to improve their care, the results of this study showed that foot reflexology seems to be a promising complement to conventional antiemetic drugs. To assess the performance of this intervention in routine practice, a larger study with several health care centers would be relevant with a cluster RCT. CLINICALTRIAL The present study registered with clinicaltrials.gov: NCT03508180 (28/06/2018) INTERNATIONAL REGISTERED REPORT RR2-10.2196/17232

scholarly journals Evaluation of the BDNF, NGF, NT3 and NT4 Genes Expressions in the Brains of Neonatal Mice with Hypothyroidism

2017 ◽  
Vol 7 (1) ◽  
pp. 171
Author(s):  
Hamid Reza Adeli Bhroz ◽  
Kazem Parivar ◽  
Iraj Amiri ◽  
Nasim Hayati Roodbari
Keyword(s):  
Dose Group ◽  
Low Dose ◽  
Pure Water ◽  
Intervention Group ◽  
Control Group ◽  
High Dose ◽  
Endocrine Glands ◽  
Blood Samples ◽  
High Doses ◽  
The Brain

Background and Aim: Thyroid is one of the endocrine glands, (T3 and T4) play a significant role in the development of prenatal brain and the following stages. The study aimed to evaluate the effect of hypothyroidism on the amount of expression of NT4, NT3, nerve growth factor (NGF) and brain-derived neurotrophic factor (BDNF) in brain of one-day rat neonates with hypothyroidism.Materials and Methods: In total, 25 mature mice of Albino NMRI race were selected after mating, divided into three group, control, as well as low-dose and high-dose intervention groups. Samples of the control group received pure water during pregnancy, whereas subjects of the intervention group with low and high doses of the medication were administered with 20 mg and 100 mg methimazole powder (dissolved in 100 cc water), respectively. After child delivery, blood samples were obtained from mother mice to determine the level of T3 and T4 in blood serum. Following that, the brain of one-day mice were removed by surgery and assessed to determine the amount of expression of NT4, NT3, NGF and BDNF using the complete kit of RT-PCR.Results: Levels of T4 and T3 in the control group were 28 ug/dl and 1.59 ug/dl, respectively. In the low-dose intervention group, the amounts of the mentioned hormones were 8 ug/dl and 0.85 ug/dl, significantly, indicating a significant reduction in the expression of NT4, NT3, NGF and BDNF genes, compared to the control group. Moreover, T4 and T3 were 6 ug/dl and 0.79 ug/dl in the high-dose group, respectively, conveying a significant decrease in the expression of NT4, NT3, NGF and BDNF genes, compared to the control group (P<0.05).

Intranasal dexmedetomidine to facilitate mask induction and prevent emergence delirium.

2021 ◽  
Author(s):  
Michiel Denis ◽  
Hans Goethuys ◽  
Elly Vandermeulen ◽  
Dieter Mesotten ◽  
Joris Vundelinckx
Keyword(s):  
Day Care ◽  
Recovery Room ◽  
Controlled Trial ◽  
Perioperative Period ◽  
Control Group ◽  
Care Hospital ◽  
Implementation Study ◽  
Emergence Delirium ◽  
Paediatric Patients ◽  
Randomised Controlled

Abstract Background As children are exposed to stress and anxiety during the perioperative period, pre-anaesthetic medication to facilitate induction of anaesthesia without prolonging recovery is needed. Dexmedetomidine is increasingly being used for sedation in the intensive care units and for procedural anaesthesia outside the operating room. However, the effectiveness of pre-operative sedation with intranasal dexmedetomidine in paediatric patients undergoing ambulatory surgery has not yet been well characterised. Aims To identify the effectiveness of intranasal dexmedetomidine in facilitating mask induction and preventing emergence agitation. Methods In a single centre retrospective implementation study, we compared intranasal dexmedetomidine (2 µg/kg) administration, sequentially in all paediatric patients undergoing minor urological surgery between January 2019 and July 2019 with a period in which dexmedetomidine was not administered. The outcome measures were tolerance of mask induction, post-operative sedation and the Paediatric Anaesthesia Emergence Delirium scale (PAED) score. Results The 53 children in the control group were compared with 50 children in the dexmedetomidine group during implementation. The incidence of sedation on mask induction was greater in patients given dexmedetomidine compared to those who did not receive premedication (60% versus 0%, p<0.0001). The proportion of children who were asleep but easily arousable in the recovery room and in day-care hospital was greater in the dexmedetomidine group compared to the control group. (32% versus 7% in the recovery room; p=0.004, and 20% versus 2% in day-care hospital, p = 0.002). The PAED scores did not differ between the two groups, neither in the recovery room nor in day-care hospital. Conclusion In paediatric patients undergoing small urologic surgery, premedication with intranasal dexmedetomidine in a dose of 2µg/kg provides adequate sedation and anxiolysis on mask induction and in the postoperative period. These results from an implementation study need to be confirmed in a multicentre blinded randomised controlled trial.

scholarly journals The Effects of Acupuncture on Pregnancy Outcomes of Recurrent Implantation Failure: A Systematic Review and Meta-Analysis

2021 ◽  
Vol 2021 ◽  
pp. 1-11
Author(s):  
Menglin Li ◽  
Yunyun Liu ◽  
Haoran Wang ◽  
Shuzhen Zheng ◽  
Yinhe Deng ◽  
...  
Keyword(s):  
Pregnancy Rate ◽  
Assessment Tool ◽  
Meta Analysis ◽  
Intervention Group ◽  
Control Group ◽  
Implantation Failure ◽  
Recurrent Implantation Failure ◽  
The Difference ◽  
Ivf Et

Objective. To systematically evaluate the efficacy and safety of acupuncture for patients with recurrent implantation failure (RIF) undergoing in vitro fertilization-embryo transfer (IVF-ET) and hopefully provide reliable guidance for clinicians and patients. Methods. Through searching domestic and foreign medical journals, the literature of randomized controlled trials (RCTs) of acupuncture for RIF undergoing IVF-ET was collected. RevMan 5.3 software was used for meta-analysis and Cochrane’s risk of bias assessment tool was used to evaluate the quality of the included studies. Results. Seven documents meeting the criteria were finally included. The results showed that the intervention group contributes more in outcomes including clinical pregnancy rate (RR = 1.90, 95% CI (1.51, 2.40), P < 0.05 ), biochemical pregnancy rate (RR = 1.59, 95% CI (1.27, 1.99), P < 0.05 ), embryo implantation rate (RR = 1.89, 95% CI (1.47, 2.45), P < 0.05 ), and endometrial thickness (MD = 1.11, 95% CI (0.59, 1.63), P < 0.05 ) when compared with the control group, and the difference is statistically significant. In terms of the number of embryo transfers and the type of endometrium, the difference between the acupuncture group and the control group was not statistically significant. Conclusion. Acupuncture therapy on patients with RIF can improve the pregnancy outcome of patients. It is a relatively effective treatment with satisfactory safety and suitable for clinical application. However, as the quality of the included studies is not good enough, the conclusion of this meta-analysis should be treated with caution. More double-blind RCTs equipped with high quality and large samples are expected for the improvement of the level of evidence.

scholarly journals Nursing-Mini-CEX Combined with Online and Offline Hybrid Teaching Model Application Research in Basic Nursing Training Teaching

2020 ◽  
Vol 9 (6) ◽  
pp. 51
Author(s):  
Hongmin Wang ◽  
Yaru Feng ◽  
Huan Li
Keyword(s):  
Mixed Model ◽  
Intervention Group ◽  
Control Group ◽  
Teaching Model ◽  
Traditional Teaching ◽  
Training Methods ◽  
Hybrid Teaching ◽  
Measurement Tools ◽  
The Difference ◽  
Nursing Training

Objective: To explore the application effects and countermeasures of Nursing-Mini-CEX combined with the online and offline hybrid teaching model in basic nursing training. Methods: Taking 150 students from the 2017 grade as an example, the effects of traditional teaching mode and Nursing-Mini-CEX combined with mixed model teaching were compared. Results: The performance of the intervention group combining Nursing-Mini-CEX evaluation and mixed teaching was significantly higher than that of the control group, and the difference was statistically significant (P<0.05). Conclusion: The combination of Nursing-Mini-CEX measurement tools and mixed teaching is feasible and effective in basic nursing training.

scholarly journals The Effectiveness of the Use of Nurse Safety Booklet on Nurse Knowledge in Ergonomic Injury Prevention in BIMA Hospital

2019 ◽  
Vol 4 (2) ◽  
pp. 108
Author(s):  
A. Haris ◽  
Abdul Haris
Keyword(s):  
Health Services ◽  
Intervention Group ◽  
Hospital Staff ◽  
Control Group ◽  
P Value ◽  
Research Subjects ◽  
Post Intervention ◽  
Quasi Experimental ◽  
The Difference ◽  
Nurse Knowledge

Safety has become a global issue in various sectors, including the health services sector. The hospital is one of the health service organizations that is guided to continuously improve quality by building safer and safer health services so as to get customer loyalty. Hospital staff is a major component of quality management in one of the indicators in evaluating hospital accreditation. This research uses a quasi-experimental research design pre and posttest with control group. Quasi experiment research is a study that tests an intervention in a group of research subjects and then measures the results of the intervention. Samples in this study are all nurses who are in the room of the General Hospital, Surgery and ICU Bima Hospital, which are 50 people. The results showed the results of different tests using paired t-test p value = 0.000 which can be concluded that there are differences between the intervention group and the control group, seen from the value of the difference in the intervention group is greater than the difference in the control group can be interpreted as education using more booklets affect the increase in nurse knowledge. The conclusion in this study was that there were significant differences in nurses' knowledge after being given education using pre and post intervention booklets between the intervention and control groups (p = 0.000).

Clinical Observation of Electro acupuncture Combined with Early Rehabilitation Training to Treat Hypertensive Cerebral Hemorrhage in Basal Ganglia

2021 ◽  
Author(s):  
Wei Wei ◽  
Tu Qin ◽  
Wang Yafen ◽  
Zeng Lang ◽  
Man Liao
Keyword(s):  
Cerebral Hemorrhage ◽  
Blood Stasis ◽  
Intervention Group ◽  
Clinical Treatment ◽  
Early Rehabilitation ◽  
Control Group ◽  
Rehabilitation Training ◽  
Significant Difference ◽  
The Difference ◽  
Hypertensive Intracerebral Hemorrhage

In this study, we investigated the clinical efficacy and poor prognosis of patients with limb disorders after the operation of hypertensive cerebral hemorrhage, using the treatment of removing blood stasis and Shengxin acupuncture combined with early rehabilitation training using a randomized trial. A total of 100 patients with hypertensive intracerebral hemorrhage who underwent surgery in our hospital from May 2019 to May 2021 were selected and divided into control group were treated with early rehabilitation training, and the intervention group was treated with acupuncture for removing blood stasis and promoting new acupuncture based on the control group. We observed that there was no significant difference in the evaluation of limb function recovery between the two groups of patients (P>0.05). After the intervention, the modified Ashworth score, FMA score, and B1 index of the two groups were significantly different in the ADL scores and the scores of families and friends support were remarkably improved. The clinical treatment efficiency of the intervention group was 94.00%,significantly higher than that of the control groupof80.00%, and the difference was statistically significant (P<0.05). The study demonstrated that the rehabilitation training combined with removing blood stasis and Shengxin acupuncture is significantly better than rehabilitation training alone to improve postoperative limb dysfunction, daily life and quality of life and is a clinical treatment for hypertension.

The effect of continuous care model-based intervention on the quality of sleep in menopausal women: A clinical trial study

2019 ◽  
Author(s):  
Farzaneh AKBARI ◽  
sousan Heydarpour ◽  
Nader Salari
Keyword(s):  
Clinical Trial ◽  
Intervention Group ◽  
Control Group ◽  
Quality Of Sleep ◽  
Care Model ◽  
Continuous Care ◽  
Menopausal Women ◽  
Significant Difference ◽  
The Difference

Abstract BACKGROUND Sleep disorder, brings in many physical, behavioral, and mental problems. Applying continuous care model leads to proper recognition of the patient’s problems and involves the patient in solving health problems. This study aimed to determine the effect of continuous care model on the quality of sleep in menopausal women. METHODS AND MATERIALS A random clinical trial study was carried out with participation of 110 menopausal women visiting Kermanshah-based clinics (the west of Iran) in 2017. The participants were randomly assigned to intervention (n=55) and control (n=55) groups. The control group received the routine cares and in addition to the routine cares the intervention group attended four weekly group consultation sessions (60-90min). The quality of sleep in the two groups was assessed using Pittsburg Sleep Quality Index before, immediately after, and one month after the intervention. Data analyses were done using independent t-test, ANOVA with frequent measures, Friedman’s test, Wilcoxon’s post hoc test, and X2 test in SPSS (24). RESULTS The mean scores of quality of sleep before and after the intervention were significantly different in the intervention group (p=0.001). There was no significant difference between the two groups in terms of quality of sleep before (p=0.140) and immediately after the intervention (p=0.168). However, one month after, the difference between the two groups was significant (P<0.001). CONCLUSION Implementation of the continuous care model led to an improvement of quality of sleep in the menopausal women.

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