scholarly journals Blood Group Discrepancies at a Regional Blood Center

Author(s):  
Hayedeh Javadzadeh Shahshahani ◽  
Azam Hayati

Background: Blood group testing is an important part of supplying safe blood components in blood transfusion centers. Blood group discrepancy develops when reactions in forward grouping do not correspond with reverse grouping or if the preceding and recent results do not match. This study aimed to evaluate ABO blood group discrepancies among blood donors of Yazd, Iran. Materials and Methods: In this cross-sectional study, data of blood donors were obtained from the integrated database of Yazd Blood Transfusion Center during a period of eight years (2010 – 2017). Tube testing was used for determining the ABO blood groups. A serological workup was performed for diagnosis and determination of the discrepancy. Confirmation of the results was accomplished by the reference laboratory of immunohematology. Results: Blood group discrepancies were detected in 130 (0.04%) out of 322,222 donations. Technical/Clerical errors leading to ABO discrepancy were noticed in 12 (9.3%) cases. The most frequent cause of ABO discrepancies in forward grouping was subgroups of A Antigen (44.6%) and in reverse grouping was cold autoantibody (23.9%). There were 11 (8.4%) cases with alloantibodies. Two blood donors with rare Bombay phenotype and p blood group were also identified. Conclusion: For minimizing Technical/Clerical errors, accurate blood donor or sample identification programs should be implemented. All cases of blood group discrepancies should be carefully investigated, and blood donors should be informed appropriately.

2005 ◽  
Vol 12 (04) ◽  
pp. 368-371
Author(s):  
ABDUL REHMAN ◽  
Muhammad Akram Saeed ◽  
MUHAMMAD AYUB KHAN ◽  
Ahmad Rafique ◽  
MUHAMMAD ASHRAF ◽  
...  

`Objective: To know the prevalence of ABO and Rhesus blood groups.Design: Observational cross sectional study. Setting: Blood transfusion Center Tehsil Headquarter HospitalLiaquatpur. Subjects and Methods: The data of blood donors from 2001 to 2003. Results: Total numbers of donorsstudied were 1389. The commonest ABO blood group was O present in 44.56% (CL 41.97% - 47.20%) followed byB in 32.54% (CL 30.13% - 35.06%), A in 20.88% (CL 18.82% - 23.10%) and AB in 2.02% (CL 1.39% - 2.91%) donorswhile 90.35% (CL 88.68% - 91.80%) donors were Rh +ve and 9.65% (CL 8.20% - 11.32%) were Rh -ve. Thecommonest ABO +ve group was O +ve present in 40.03% (CL 37.48% - 42.69%) followed by B +ve in 30.31% (CL27.95% - 32.78%), A +ve in 18.21% (CL 16.27% - 20.34%) and AB +ve in 1.8% (CL 1.21% - 2.66%) donors. The mostcommon ABO -ve was O -ve present in 4.54% (CL 3.56% - 5.77%), A -ve in 2.66% (CL 1.93% - 3.66%), B -ve in 2.23%(CL 1.57% - 3.17%) donors. Conclusion: Blood group O is the commonest ABO blood group and 90.35% are RH +vein this area.


Mediscope ◽  
2015 ◽  
Vol 2 (1) ◽  
pp. 22-26
Author(s):  
RM Hira ◽  
LK Dhali ◽  
ND Dhali ◽  
DK Akash

This is an observational cross-sectional study aiming to identify the distribution patterns of ABO and Rh-D blood group in a rural population of Bagerhat District, Bangladesh in order to promote social awareness and safe blood transfusion among the population. After proper ethical consideration, a total of 164 people of a village in Bagerhat District were included in this study. They were selected irrespective of age and sex by systematic random sampling. ABO and Rh-D blood groups were determined by the antigen antibody agglutination test of slide method. The ABO group distribution, O (34.1%), A (26.2%), B (25.6% and AB (14.0%). Of the respondents, 105 (64.0%) were male and 59 (36.0%). The frequency of group O+ve comprised the highest (32.9%) of the samples followed by group A+ve, B+ve and AB+ve. The majority of the subjects were Rh-D positive (94.5%). It is observed that Rh-D positive group is more common in subjects with O group whereas Rh-D negative group is more common in B group. Most common blood group among this village population was O+ve which can safely be transfused to any other group. The study of blood grouping can generate database and create social awareness about self-blood grouping and safe blood transfusion among the population.Mediscope Vol. 2, No. 1: 2015, Pages 22-26


PLoS ONE ◽  
2021 ◽  
Vol 16 (3) ◽  
pp. e0249061
Author(s):  
Alex Mremi ◽  
James J. Yahaya ◽  
Mramba Nyindo ◽  
Edson Mollel

Background Blood transfusion saves many people every year that would otherwise have died. The present study aimed to provide an update and insightful information regarding prevalence of the common Transfusion-Transmitted Infections (TTIs) and associated factors among blood donors in Tanzania. Methods This was a cross-sectional study involving retrospectively collected data of blood donors from the Tanzania Northern Zone Blood Transfusion Center between 2017 and 2019. Descriptive statistics were performed to describe characteristics of the blood donors. Univariable and multivariable logistic regression analyses were performed to determine association between prevalence of TTIs and socio-demographic factors. P-value <0.05 was considered statistically significant. Results A total of 101, 616 blood donors were included in the present study of which 85,053(83.7%) were males while 16,563 (16.3%) were females. Of all participants, the majority 45,400 (44.7%) were aged between 18 and 25 years; 79,582 (78.3%) were voluntary non-remunerated donors while 22,034 (21.7%) were replacement donors. The vast majority of them 99,626 (98%) were first time blood donors while 1990 (2%) were multiple donors. The overall prevalence of TTIs was 10.1% (10,226 out of 101,616) of which the leading was HBV accounting for 5.1% (5,264 out of 101,616). Being a replacement donor was associated with all the four types of TTIs: HIV (AOR = 1.22, 95% CI = 1.10–1.35), HBV (AOR = 1.35, 95% CI = 1.27–1.44), HCV (AOR = 1.28, 95% CI = 1.12–1.46), and syphilis (AOR = 1.33, 95% CI = 1.20–1.48). Conclusions Our study has demonstrated that Tanzania has relatively high prevalence of TTIs compared to some countries in Sub-Saharan Africa. HBV infection seems to be the most common infection among blood donors and replacement blood donors are at a higher risk of harboring the commonest TTIs among blood donors.


2006 ◽  
Vol 13 (01) ◽  
pp. 23-26
Author(s):  
MUHAMMAD AYUB KHAN ◽  
Muhammad Ashraf ◽  
ABDUL REHMAN ◽  
Azam Ali ◽  
MUHAMMAD ASHRAF ◽  
...  

Objective: To know the prevalence of hepatitis B, hepatitis C and HIV.Design: Observational cross sectional study. Setting: Blood Transfusion Center Tehsil Headquarter HospitalLiaquetpur. Subjects and Methods: The data of blood donors from 2001 to 2003. Results: Total blood donors studiedwere 1426. The prevalence for hepatitis B was 5.96% (CL 4.84%-7.32%) It was 0.07% (CL <0.01% - 0.44%) for HCVand zero for HIV. The prevalence of HBV in males was 6.03% (CL 4.87%-7.45%) while 5.05% (CL 1.91%-11.63%) infemales (p=0. 6917). The prevalence in 17-20 years age group was 6.4% (CL 3.92%-10.23%), 5.81% (CL 4.6%-7.33%)in 21-40 years age group and in 41-60 years age group it was 4.35% (CL 1.33%-28.19%) [p=0.9029]. Conclusion:Hepatitis B is common, hepatitis C is an uncommon health problem while HIV is not present in this area.


2019 ◽  
Author(s):  
Mohamed Aabdien ◽  
Nagah Selim ◽  
Sayed Mohamed Himatt ◽  
Saloua Hmissi ◽  
Zeyd Merenkov ◽  
...  

Abstract Background: Millions of lives around the world are being saved annually through blood transfusion. However, blood transfusion is among the important vehicles for transmitting infections. The overall prevalence of Transfusion Transmissible Infections (TTIs) among blood donors differs around the world, reflecting the variation in the prevalence of these infections. The aim of this study is to assess the prevalence and trends of TTIs among blood donors in Qatar. Methods: This is a cross sectional study utilizing donation records of a five-year period from January 2013 to December 2017. Results for all screening and confirmatory tests for Hepatitis B Virus (HBV), Hepatitis C Virus (HCV), Human T-Lymphotropic Virus-I/II (HTLV-I/II), Syphilis and Malaria were included in the study. Results: Among the 190,509 donations received at the donation center during the study period, about 91% donations were received from males and 9% from females. The overall positivity rate for all tests were 1.95, 2.18, 1.62, 1.81 and 1.85 for the years 2013 through 2017. The overall positivity rates for HBV, Syphilis and Malaria were 0.30, 0.43 and 0.20, respectively. Throughout the years, the positivity rates decreased for HBV, Syphilis and Malaria and increased for HCV and HTLV. Conclusion: The overall positivity rate of all tests combined for the TTIs demonstrated a gradual increasing trend from 2013 to 2017. The rates for HCV and HTLV showed increasing trends too. To support developing effective prevention and control strategies, further investigations are needed to improve the estimations of the prevalence of these infections.


2020 ◽  
Vol 3 (1) ◽  
pp. 14-17
Author(s):  
Faris Mohamed Awad Abdon ◽  
◽  
Elias Teages Adgoy ◽  
Nahom Yacob Berhane ◽  
Senet Awolker Ibrahim ◽  
...  

Background: Platelets are an important constituent of blood. Safety measures of blood transfusion are important for optimum health environment. To the knowledge of the researchers, there is no study that was conducted concerning Platelets count in apparently healthy Eritrean blood donors. Therefore, this study will help in establishing the reference ranges of Platelets count in them. Objectives: To measure the serum platelets levels and mean platelets volume in apparently healthy Eritrean blood donors attending the national blood bank of Eritrea. Study design: Descriptive crosssectional study. Materials and methods: 610 Blood donors were incorporated in the study. 4 ml of venous blood was collected into K3EDTA tubes (Becton Dickinson, Plymouth, UK) from all of the participants of the study. Blood samples collected into the (EDTA)-tubes were examined for Platelets count and mean platelet volume. Results: The overall mean of platelets count was 267.145 ± (65.915) ×109 /L, The median and mode of values were both 266.3 thousands/mm3. The mean platelet count for the females was 296.122 thousands /mm3, and for males was 252.477 ×109 /L, and the statistic difference between them was significant. The statistic mean of MPV for males was 8.763 fl, and for females was 8.717, and the difference between the two means also considered insignificant. Conclusion: This descriptive cross sectional study was performed in the National Blood bank in Asmara where platelets levels and mean platelets volume were measured for 610 healthy blood donors. The results were found to be within reference normal ranges. The difference between the males and females results was statistically significant


2021 ◽  
Vol 8 (29) ◽  
pp. 2615-2619
Author(s):  
Indu Pachampully Kumaran ◽  
Archana K.A ◽  
Meena Dharmadas ◽  
Sasikala Nadanganan ◽  
Anu Kumar B ◽  
...  

BACKGROUND Even in the presence of sufficient voluntary blood donors, the need of blood is not met yet. We wanted to evaluate the causes that hinder the smooth functioning of well-maintained blood transfusion services (BTS). METHODS This is a population based cross-sectional study conducted among blood donors from voluntary outreach blood donation camp for period of one year. Total 1536 blood donors from 32 blood donation camps were subjected to study for the sociodemographic characteristic and their knowledge of blood donation. Statistical analysis of data was done using Microsoft Excel, analysed using statistical package for social sciences (SPSS) ver.16 software. RESULTS A total of 32 blood donation camps were conducted during the study period that provided 1536 donors. In most of the camps, male donors (75 %) were more than female donors. Donors of age group of 30 to 39 years (43.9 %) were more when compared to others. Donors those who were married accounted for 79.9 %. Blood donors of Hindu religion (53 %) were more. CONCLUSIONS The main hindrance for blood donor motivation is lack of knowledge. Literacy and chance to mingle in society have a positive effect on blood donor motivation. Targeting of effective donor motivation, recruitment, and retention were attained by conducting awareness classes, seminars, workshops, and visual communication modalities. KEYWORDS World Health Organization, Altruistic Blood Donor, Blood Transfusion Services, Transfusion Transmitted Infections, Blood Components and Plasma Derivatives, Director General of Health Services (DGHS), National Blood Transportation Council (NBTC)


2019 ◽  
Vol 6 (1) ◽  
pp. 33-38
Author(s):  
Gyanendra Bikram Shah ◽  
Krishna Gurung ◽  
Bharat Prasad Baral ◽  
Ram Raja Gurung ◽  
Balkrishna Bhattachan

Hepatitis B Virus (HBV) and Hepatitis C Virus (HCV) infections lead to chronic diseases and are the most common causes of liver cirrhosis and cancer in developing countries like Nepal. The study is carried out to determine the seroprevalence of HBV and HCV by using a Rapid kit method and Elisa Method to find out its risk factors. The cross-sectional study was done among blood donating people from 16th August 2016 to 19th November 2016. Blood donors in Pokhara Valley were screened for anti-HCV antibodies, anti-HBV antibodies using third generation ELISA kits and automated ELISA Processor in serology laboratory at Central Blood Transfusion Service (CBTS) of Nepal Red Cross Society (NRCS) in Pokhara, Nepal. 1777 (87.2%) units were male blood donors and 260 (12.6%) units were female donors out of 2037 participants. Gender wise, the ratio between male and female was 1:0.1. HBV and HCV infection rate in blood donors were detected at 0.7% (15/2037) and 0.5% (8/2037) respectively. HBV infection rate in volunteer blood donor people was 0.7% (14/1881) which was higher than the replacement donors i.e. 0.6% (1/156). Similarly, in HCV infection rate in volunteer donor were 0.4% (8/1881). HBV infected people are detected higher than the HCV infected people among the blood donors. In addition, there was no significant relationship between positive results of HBV and HCV tests with the gender, age, tattoo, donor type.


2020 ◽  
Vol 15 (1) ◽  
pp. 71-74
Author(s):  
AKM Shafiqur Rahman ◽  
Md Arifuzzaman ◽  
Md Mehedhi Hasan Shourov ◽  
Farzana Zafreen

Introduction: Blood transfusion is a significant life-saving intervention in the present era of patient management system. As the blood and blood products are a potential source of infections and the necessity of transfusion is increasing day by day, transfusion transmissible infections have become a major threat to the system of ensuring safe transfusion. Objectives: To find out the sero-prevalence of Hepatitis B, Hepatitis C, HIV, Syphilis and Malaria parasite among the blood donors and to ascertain risk behaviour of the blood donors. Materials and Methods: This descriptive cross-sectional study was conducted on purposively selected 115 blood donors at Armed Forces Institute of Pathology (AFIP) during the period of 1st September to 31st December 2011. Results: The study revealed among 115 blood donors 7.8% were HBsAg positive. More than half of the HBsAg positive cases 66.67% were from civilian. None of the respondents was found positive for anti-HCV, VDRL, Malaria and anti-HIV. All of the donors in this study were voluntary donors. The sample studied had a mean age of 28.03 ± 6.79 years and 90.5% of donors were belongs to age group 18-37 years and female was only 6.1%. Most of the donors (49.5%) were military personnel,86%above SSC educated and 22.6% had visited abroad. Regarding risk behaviour 38.3% had the history of undertaking dental procedure, 0.9% were found undertaking blood transfusion, 2.6% had the history of illicit sex and 29.6% had the history of suffering from jaundice and among them only 1.7% were found HBsAg positive. Conclusion: The study finding demands motivation against unnecessary blood transfusion. It also emphasize health education programme among peoples having risk behaviour. Journal of Armed Forces Medical College Bangladesh Vol.15 (1) 2019: 71-74


2017 ◽  
Vol 6 (2) ◽  
pp. 12-14
Author(s):  
Nilufar Begum ◽  
Amdadul Haque ◽  
Fatema Akhter Tumpa

This cross sectional study was done at department of Transfusion Medicine in Community Based Medical College (CBMCB) to know the Prevalence of ABO blood group and Rh group systems among the students selected for admission into CBMCB. Sample size was 555. Male female ratio was 67:33 with mean age was ±19 years. Maintaining aseptic precaution blood samples were collected by venepuncture with disposable syringe without anticoagulant. Antigen-antibody agglutination test was done in slide method for ABO and Rh(D) blood grouping by mixing individual blood sample with Anti A, Anti -B, Anti-D human antisera. Results were taken by visually and under microscope in low power. Blood group differs person to person due to genetically determined antigen. This study showed highest frequency of blood group B (33.5%) followed by O (32.5 %), A (23.37%) and AB (10.63%) in ABO system and In Rhesus system, frequency of Rh-positive was 97.12% and Rh-negative was 2.88%. Results were comparable with different foreign studies. Fair blood grouping assist the safe blood transfusion and reduce the morbidity and mortality considerably. CBMJ 2017 July: Vol. 06 No. 02 P: 12-14


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