The relationship between problemsolving ability and fatigue severity in people with multiple sclerosis

Author(s):  
Seyed Alireza Derakhshanrad ◽  
Emily Piven

Background: The literature speculates that there may be a relationship between cognitive capacities and levels of fatigue in people with multiple sclerosis (MS), which has been under reported. This study has investigated one aspect of cognition by evaluating the association between problem-solving ability and the severity of fatigue. Methods: A cross-sectional, descriptive study was used to investigate the association between levels of problem-solving ability and degrees of fatigue severity. Eighty-five participants living in the city of Shiraz, Iran, completed Cassidy Problem-Solving Inventory (PSI) and the Fatigue Severity Scale (FSS). Pearson’s Product Moment Correlation Coefficient was used to analyze the data. Results: Problem-solving was inversely associated with fatigue (r = -0.381, P = 0.009), whereby higher levels of problem-solving ability were associated with lower degrees of fatigue. Conclusion: The results of this study contributed to the ongoing debate about the linkage between cognition and fatigue in people with MS, suggesting an association between problem-solving ability and fatigue severity. A possible implication would be the importance of problem-solving training for people with MS.

2003 ◽  
Vol 9 (5) ◽  
pp. 509-514 ◽  
Author(s):  
A Lerdal ◽  
E G Celius ◽  
T Moum

Objective: To explore the relationship between fatigue, sociodemographic and clinical variables in a population of patients with multiple sclerosis (MS). Rationale: There is a need to identify empirical relationships with possible antecedents of fatigue among patients with MS. Methods: A mailed questionnaire designed to survey sociodemographic variables and the Fatigue Severity Scale (FSS) was mailed to 502 individuals from the population of patients with definite MS in the city of O slo. A total of 368 (73%) responded. C linical data were collected from the O slo C ity MS-Registry. Results: The prevalence of fatigue in this population was 60.1%. The FSS score showed a negative correlation with education (r =-0.15, P <0.01) and a positive correlation with age (r =0.20, P B-0.001) and time since disease onset (r =0.11, P B-0.05). When controlled for gender, level of education and time since disease onset, the data showed a positive relationship between fatigue and age (P B-0.001) among patients with primary progressive (PP) disease. This relationship between age and fatigue was not found among patients with relapsing-remitting/secondary progressive (RR/SP) disease. Conclusion: The negative relationship between level of formal educatio n (FE) and fatigue among individuals with RR/SP disease suggests that behavioral factors may be among the antecedents of fatigue in this patient group. In contrast to normative data from the general population, our findings revealed no differences in fatigue related to gender. Thus, this study supports the hypothesis that there are disease-specific antecedents of fatigue among patients with MS.


Author(s):  
Sandra Neate ◽  
Afaf Humam ◽  
Nupur Nag ◽  
George A. Jelinek ◽  
Steve Simpson-Yap

Abstract Background Mastery is the extent to which an individual perceives their life circumstances as being under their control and not predominantly influenced by external factors. The relationship of mastery with clinical outcomes in people with multiple sclerosis (pwMS) has not been well-researched. We assessed the relationships of mastery with fatigue, disability, relapse number, and depression risk among pwMS over 2.5 years’ follow-up. Methods Data from the Health Outcomes and Lifestyle in a Sample of people with Multiple sclerosis study, among 839 participants who completed the 2.5 and 5-year reviews, were analysed. Mastery was measured by the Pearlin Mastery Scale, fatigue by Fatigue Severity Scale, depression risk by Patient Health Questionnaire-9, and disability by Patient-Determined Disease Steps, and diagnosed relapse number in the previous 12 months was queried. Cross-sectional and prospective analyses were undertaken by log-binomial, log-multinomial, and Poisson regression, as appropriate, adjusted for relevant confounders. Results Cross-sectionally, pwMS with the highest quartile mastery (> 25/28) had 90% lower frequency of depression risk, 60% lower frequency of clinically significant fatigue, and 77% fewer had severe disability, all largely robust to adjustment. Prospectively, those in the top two quartiles of mastery (> 21–25, > 25/28) had 66% and 74% lower subsequent depression risk, robust to adjustment. No significant associations were seen prospectively for change in fatigue, disability, or relapse number, however, and no robust associations of mastery with relapse number were evident. Conclusions Prospectively, a protective relationship of mastery with subsequent risk of depression was observed, suggesting this may be a point of intervention to improve wellbeing in pwMS.


2021 ◽  
Author(s):  
Sandra Neate ◽  
Afaf Humam ◽  
Nupur Nag ◽  
George Jelinek ◽  
Steve Simpson-Yap

Abstract Background: Mastery is the extent to which an individual perceives their life circumstances as being under their control and not predominantly influenced by external factors. The relationship of mastery with clinical outcomes in people with multiple sclerosis (pwMS) has not been well-researched. We assessed the relationships of mastery with fatigue, disability, relapse number, and depression risk among pwMS over 2.5 years’ follow-up. Methods: Data from the Health Outcomes and Lifestyle in a Sample of people with Multiple sclerosis (HOLISM) study, among 839 participants who completed the 2.5 and 5-year reviews, were analysed. Mastery was measured by the Pearlin Mastery Scale, fatigue by Fatigue Severity Scale, depression risk by Patient Health Questionnaire-9, and disability by Patient-Determined Disease Steps, and diagnosed relapse number in the previous 12 months was queried. Cross-sectional and prospective analyses were undertaken by log-binomial, log-multinomial, and Poisson regression, as appropriate, adjusted for relevant confounders. Results: Cross-sectionally, pwMS with the highest quartile mastery (>25/28) had 90% lower depression risk, 60% lower frequency of clinically significant fatigue, and 77% fewer with severe disability, all largely robust to adjustment. Prospectively, those in the top two quartiles of mastery (>21-25, >25) had 66% and 74% lower depression risk, robust to adjustment. No significant associations were seen prospectively for change in fatigue, disability, or relapse number, however, and no robust associations of mastery with relapse number. Conclusions: Prospectively, a protective relationship of mastery with subsequent risk of depression was observed, suggesting this may be a point of intervention to improve wellbeing in pwMS.


2006 ◽  
Vol 12 (4) ◽  
pp. 481-486 ◽  
Author(s):  
B R Stanton ◽  
F Barnes ◽  
E Silber

Fatigue is common in multiple sclerosis (MS) and is an important cause of disability. However, the cause of fatigue is poorly understood. This study aimed to describe the frequency and pattern of sleep disturbance in a group of outpatients with MS, and to investigate the relationship between sleep disturbance and fatigue. Sixty outpatients with MS completed the Fatigue Severity Scale (FSS) and the Epworth Sleepiness Scale and kept a sleep diary for seven days. Fatigue and excessive daytime sleepiness were common in this group of patients (64 and 32%). Sleep problems on at least two nights per week occurred frequently, including initial insomnia in 42%, middle insomnia in 53% and terminal insomnia in 58%. The reasons cited for different types of insomnia varied, with anxiety and pain/discomfort being the commonest causes of initial insomnia and nocturia the commonest cause of middle insomnia. Middle insomnia was significantly correlated with daytime fatigue, a relationship that remained after controlling for disability. Sleep disturbance is common in MS and is associated with treatable symptoms, including pain and nocturia. Sleep disturbance may be an important factor contributing to fatigue in patients with MS.


2016 ◽  
Vol 2016 ◽  
pp. 1-5 ◽  
Author(s):  
Christian Veauthier ◽  
Gunnar Gaede ◽  
Helena Radbruch ◽  
Klaus-Dieter Wernecke ◽  
Friedemann Paul

Objectives. Pittsburgh Sleep Quality Index (PSQI) values correlate with depression, but studies investigating the relationship between PSQI values and polysomnographic (PSG) data showed inconsistent findings.Methods. Sixty-five consecutive patients with multiple sclerosis (MS) were retrospectively classified as “good sleepers” (GS) (PSQI ≤ 5) and “poor sleepers” (PS) (PSQI > 5). The PSG data and the values of the Visual Analog Scale (VAS) of fatigue, Modified Fatigue Impact Scale (MFIS), Fatigue Severity Scale (FSS), Epworth Sleepiness Scale (ESS), and the Beck Depression Inventory (BDI) were compared.Results. No significant differences were found either for PSG data or for ESS, MFIS, and FSS values; but PS showed significantly increased BDI and VAS values.Conclusions. Poor sleep is associated with increased depression and fatigue scale values.


2020 ◽  
Vol 8 (1) ◽  
pp. 213-220
Author(s):  
L Anagonou ◽  
Houinou Ebo B ◽  
F Adeossi ◽  
E Klikpo ◽  
S Salifou ◽  
...  

The developmental path of the minor may be marked by particular situations such as conflicts with the law, various crimes. The situations, contexts and processes that lead to crime are multiple. Thus, the aim of our research was to study the characteristics of minors judged for crime, seen in a judicial space. This was a retrospective, cross-sectional, descriptive study carried out at the Cotonou First Instance Court. Data were collected from the judicial files of minors tried for crime by the juvenile court ruling on criminal matters from 1 January 2011 to 31 December 2015; 34 files were taken into account. The respondents were all adolescents aged between 10 and 18 years. The majority of them were tried for homicide (61.7%) and rape (32.4%). For 35.3% of the minors tried for crime, the relationship with opposite sex parent had poor quality. These minors received a firm prison sentence (88.2%), and 11.8% of them were placed in a foster centre without receiving a prison sentence. Crimes committed by minors calls into question our ability to supervise and provide a safe and appropriate framework for the psychological construction of children and adolescents in our society. Measures should be taken in terms of prevention at various levels to reduce the risk of children developing criminal behaviour.


2020 ◽  
Vol 34 (8) ◽  
pp. 1103-1111
Author(s):  
Marzieh Mortezanejad ◽  
Fatemeh Ehsani ◽  
Nooshin Masoudian ◽  
Maryam Zoghi ◽  
Shapour Jaberzadeh

Objective: To compare the effects of anodal trans-cranial direct current stimulation (a-tDCS) over primary motor and dorsolateral prefrontal cortices on Fatigue Severity Scale and its lasting effect on fatigue reduction and improvement in quality of life in patients with multiple sclerosis. Design: A randomized, double-blinded, sham-controlled parallel clinical trial study. Setting: Neurological physiotherapy clinics. Subjects: Thirty-nine participants were randomly assigned to three groups: dorsolateral prefrontal cortex a-tDCS, primary motor a-tDCS (experimental groups) and sham a-tDCS. Finally, 36 participants completed the whole study ( n = 12 in each group). Interventions: Participants in the experimental groups received six-session a-tDCS (1.5 mA, 20 minutes) during two weeks (three sessions per week). The sham group received six sessions of 20-minute sham stimulation. Main measures: The Fatigue Severity Scale and quality of life were assessed before, immediately and four weeks after the intervention. Results: Findings indicated a significant reduction in the Fatigue Severity Scale and a significant increase in the quality of life in both experimental groups, immediately after the intervention ( P < 0.001), while Fatigue Severity Scale and quality of life changes were not significant in the sham a-tDCS group ( P > 0.05). In addition, improvement of the variables remained four weeks after the intervention in dorsolateral prefrontal cortex a-tDCS (mean differences (95% confidence interval): 0.03 (−0.63 to 0.68) as compared to primary motor (−0.62 (−0.11 to −1.14) and sham a-tDCS groups (−0.47 (−1.37 to 0.43)). Conclusion: Both primary motor and dorsolateral prefrontal cortex a-tDCS as compared to sham intervention can immediately improve fatigue and quality of life. However, the effects last up to four weeks only by the dorsolateral prefrontal cortex a-tDCS.


2016 ◽  
Vol 12 (8) ◽  
pp. 192 ◽  
Author(s):  
Saeed Ariapooran ◽  
Masuod Rajabi ◽  
Amirhosein Goodarzi

<p><strong>Introduction:</strong> Patients with Multiple Sclerosis (MS) are at risk for Suicide Ideation (SI). The relationship between Social Support (SS) and Time Perspective (TP) with SI is important among patients with MS. This study was performed to determine the prevalence of SI and the correlation between SS and TP with SI in Iranian patients with MS in Nahavand and Malayer.</p><p><strong>Methods:</strong> Using a cross-sectional analytic research design, we selected 79 participants among patients with MS in Nahavand and Malayer, Iran. Beck Scale for Suicidal Ideation, Multidimensional Scale of Perceived Social Support and Zimbardo’s Time Perspective Inventory were used for collecting the data.</p><p><strong>Results:</strong> The obtained results indicated that 30.3% of the patients with MS suffered from SI. There was a negative correlation between SS (from family, friends and significant other), Past Positive (PP) and Future (F) orientations and a positive correlation between Past Negative (PN) orientation and SI; SS from significant other and PP negatively predicted the SI in patients with MS.</p><p><strong>Conclusion: </strong>Based on the obtained results, the relationship between SS, PN, PP, F and SI and the role of SS from significant other and PP in predicting the SI in Nahavand and Malayer patients with MS were confirmed. Thus, it is necessary to develop support systems and apply the TP-based treatments for patients with MS who are at risk for SI.</p>


2005 ◽  
Vol 11 (4) ◽  
pp. 469-476 ◽  
Author(s):  
Sharon G Lynch ◽  
Brett A Parmenter ◽  
Douglas R Denney

Background: The association between cognitive impairment and physical disability was examined in a larger, more representative sample of patients with multiple sclerosis (MS) than in previous studies. Method: Two hundred and fifty-three patients attending an MS clinic were assessed with respect to physical disability using the Expanded Disability Status Scale and cognitive impairment using a battery of neuropsychological tests. Results: Physical disability correlated with duration of disease; cognitive impairment did not. Virtually all measures derived from the cognitive battery were significantly correlated with physical disability. Three measures of speeded information processing and one involving delayed recall of verbal material were unique predictors of disability status. The relationship between cognitive impairment and physical disability was equivalent for patients with shorter (<3 years) versus longer (>10 years) disease duration. Cognitive impairment correlated with the rate of disability progression as reflected by the progression index. Conclusion: Cognitive impairment is more closely associated with physical disability than most previous studies indicate. This relationship appears to be stable throughout the duration of MS, although this conclusion is qualified by the cross-sectional design of the study. Further attention should be paid to cognitive impairment as a possible predictor of the rate of patients’ physical decline.


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