The association between cognitive impairment and physical disability in multiple sclerosis

2005 ◽  
Vol 11 (4) ◽  
pp. 469-476 ◽  
Author(s):  
Sharon G Lynch ◽  
Brett A Parmenter ◽  
Douglas R Denney
Keyword(s):  
Multiple Sclerosis ◽  
Cognitive Impairment ◽  
Physical Disability ◽  
Cross Sectional ◽  
Delayed Recall ◽  
Physical Decline ◽  
Disability Status ◽  
Duration Of Disease ◽  
Cross Sectional Design ◽  
The Relationship

Background: The association between cognitive impairment and physical disability was examined in a larger, more representative sample of patients with multiple sclerosis (MS) than in previous studies. Method: Two hundred and fifty-three patients attending an MS clinic were assessed with respect to physical disability using the Expanded Disability Status Scale and cognitive impairment using a battery of neuropsychological tests. Results: Physical disability correlated with duration of disease; cognitive impairment did not. Virtually all measures derived from the cognitive battery were significantly correlated with physical disability. Three measures of speeded information processing and one involving delayed recall of verbal material were unique predictors of disability status. The relationship between cognitive impairment and physical disability was equivalent for patients with shorter (<3 years) versus longer (>10 years) disease duration. Cognitive impairment correlated with the rate of disability progression as reflected by the progression index. Conclusion: Cognitive impairment is more closely associated with physical disability than most previous studies indicate. This relationship appears to be stable throughout the duration of MS, although this conclusion is qualified by the cross-sectional design of the study. Further attention should be paid to cognitive impairment as a possible predictor of the rate of patients’ physical decline.

Disclosure of disease status among employed multiple sclerosis patients: Association with negative work events and accommodations

2014 ◽  
Vol 21 (2) ◽  
pp. 225-234 ◽  
Author(s):  
Seth E Frndak ◽  
Victoria M Kordovski ◽  
Diane Cookfair ◽  
Jonathan D Rodgers ◽  
Bianca Weinstock-Guttman ◽  
...  
Keyword(s):  
Multiple Sclerosis ◽  
Cognitive Impairment ◽  
Physical Disability ◽  
Psychiatric Symptoms ◽  
Disease Status ◽  
Adaptive Strategy ◽  
Cross Sectional ◽  
Disclosure Status ◽  
Multiple Sclerosis Patients

Background: Unemployment is common in multiple sclerosis (MS) and detrimental to quality of life. Studies suggest disclosure of diagnosis is an adaptive strategy for patients. However, the role of cognitive deficits and psychiatric symptoms in disclosure are not well studied. Objective: The goals of this paper were to (a) determine clinical factors most predictive of disclosure, and (b) measure the effects of disclosure on workplace problems and accommodations in employed patients. Methods: We studied two overlapping cohorts: a cross-sectional sample ( n = 143) to determine outcomes associated with disclosure, and a longitudinal sample ( n = 103) compared at four time points over one year on reported problems and accommodations. A case study of six patients, disclosing during monitoring, was also included. Results: Disclosure was associated with greater physical disability but not cognitive impairment. Logistic regression predicting disclosure status retained physical disability, accommodations and years of employment ( p < 0.0001). Disclosed patients reported more work problems and accommodations over time. The case study revealed that reasons for disclosing are multifaceted, including connection to employer, decreased mobility and problems at work. Conclusion: Although cognitive impairment is linked to unemployment, it does not appear to inform disclosure decisions. Early disclosure may help maintain employment if followed by appropriate accommodations.

scholarly journals Examining the Relationship Between Family Caregivers' Emotional States and Ability to Empathize with Patients with Multiple Sclerosis

2016 ◽  
Vol 18 (3) ◽  
pp. 122-128 ◽  
Author(s):  
Sepideh Pooyania ◽  
Michelle Lobchuk ◽  
Wanda Chernomas ◽  
Ruth Ann Marrie
Keyword(s):  
Multiple Sclerosis ◽  
Cognitive Impairment ◽  
Family Caregivers ◽  
Mood State ◽  
Statistical Significance ◽  
Quality Care ◽  
Emotional States ◽  
Linear Regression Models ◽  
Cross Sectional ◽  
The Relationship

Background: Multiple sclerosis (MS) is the most common nontraumatic cause of disability affecting young adults in Canada. Caregivers of patients with MS are highly psychologically burdened. Empathy and helping behaviors are hallmarks of quality care, but when they are challenged, suboptimal patient care can result. We aimed to evaluate the prevalence of negative emotional states among primary caregivers of people with MS; the association between the caregiver's empathy-related behavior and the physical and cognitive impairment of the person with MS; and the association between the caregiver's emotional status and his or her empathy-related behaviors. Methods: We conducted a descriptive, cross-sectional pilot study with family caregivers of noninstitutionalized individuals living with MS. We used univariate linear regression models for each potential predictor. The Kruskal-Wallis test was conducted to compare differences in caregiver empathic responses depending on Profile of Mood States subscale scores. Results: Thirty percent of caregivers had elevated or very elevated mood scores, and such elevated scores were associated with greater functional impact of MS on the person with MS. Patient severity of cognitive impairment was not associated with caregiver mood scores. Caregiver mood state was not associated with empathy-related behaviors. Empathy-related behaviors were less frequent when levels of anger and hostility were higher, but this association did not reach statistical significance. Conclusions: Given the elevated levels of fatigue, depression, and anger observed among caregivers in this study, clinicians need to be aware of the potential impact of caregiving and to assess the needs of caregivers.

Cognitive impairment at diagnosis predicts 10-year multiple sclerosis progression

2015 ◽  
Vol 22 (5) ◽  
pp. 659-667 ◽  
Author(s):  
Marcello Moccia ◽  
Roberta Lanzillo ◽  
Raffaele Palladino ◽  
Kiara Chu-Mei Chang ◽  
Teresa Costabile ◽  
...  
Keyword(s):  
Multiple Sclerosis ◽  
Cognitive Impairment ◽  
Newly Diagnosed ◽  
Delayed Recall ◽  
Selective Reminding ◽  
Conversion Rates ◽  
Disability Status ◽  
Relapsing Remitting ◽  
Selective Reminding Test

Background: Cognitive impairment occurs from the early phases of multiple sclerosis (MS), and more frequently affects secondary progressive (SP) subjects than relapsing–remitting (RR). Objective: To investigate relationships between cognitive dysfunctions in newly diagnosed RRMS, and long-term MS-related outcomes. Methods: The present 10-year retrospective longitudinal study included 155 RRMS subjects, tested with the Rao Brief Repeatable Battery at MS diagnosis. The reaching of Expanded Disability Status Scale (EDSS) 4.0, and the SP conversion were recorded. Results: 67 subjects (43.2%) reached EDSS 4.0, and 34 subjects (21.9%) converted to SP during a follow-up period of 10.0±1.8 years. Subjects with cognitive impairment at diagnosis had a rate of reaching EDSS 4.0 more than three times greater ( p<0.001; HR=3.183), and a rate of SP conversion more than two times greater, as compared to cognitively preserved subjects ( p=0.008; HR=2.535). In particular, better scores in the Selective Reminding Test-Delayed Recall and in the Symbol Digit Modalities Test at baseline were associated with lower SP conversion rates during the follow-up period ( p=0.018; HR=0.835; and p=0.001; HR=0.941, respectively). Conclusion: Cognitive impairment, with particular involvement of processing speed and memory, predicts disability progression and SP conversion in newly diagnosed RRMS, highlighting the importance of cognitive assessment from the beginning of MS.

scholarly journals Depression and Cognitive Impairment in Disability-Free Early Multiple Sclerosis

2003 ◽  
Vol 14 (1-2) ◽  
pp. 39-45 ◽  
Author(s):  
Claus G. Haase ◽  
Michael Tinnefeld ◽  
Marc Lienemann ◽  
Reinhard E. Ganz ◽  
Pedro M. Faustmann
Keyword(s):  
Multiple Sclerosis ◽  
Cognitive Impairment ◽  
Physical Disability ◽  
Neuropsychological Tests ◽  
Short Term Memory ◽  
Clinical Signs ◽  
Depression Scale ◽  
Diagnostic Tools ◽  
Disability Status ◽  
Relapsing Remitting

Cognitive and emotional capabilities were evaluated in 73 female patients with stable relapsing-remitting definite, and/or laboratory-supported multiple sclerosis (MS) and were compared with 32 matched healthy controls. Patients were categorized according to their score in the expanded disability status scale (EDSS) to either no (EDSS 0,n= 33) or few clinical signs (EDSS 1–2,n= 40) of MS without physical disability. Patients with EDSS > 0 were characterized by significantly (p These results indicate that depression may present as an early sign in MS followed by cognitive impairment, in particular visuo-spatial short-term memory, before physical disability appears. Neuropsychological tests as mentioned here could serve as early diagnostic tools to detect subtle disease progression and to initiate and monitor disease modifying therapies.Patients with EDSS > 0 were characterized by significantly (p< 0.001) higher scores on “von Zerssen’s“ depression scale, compared to controls. Patients with higher EDSS scores (1–2) showed significantly decreased performance with respect to the total score of Kimura’s Recurring-Figures-Test (p< 0.001), in addition. Regarding visuo-constructive functioning, patients with EDSS = 0 performed to a significantly lower level (p< 0.001), compared to controls.

scholarly journals The Possible Direct Correlation between Cognitive Impairment and Fear of Catching COVID-19 among Patients with Multiple Sclerosis

2021 ◽  
Author(s):  
Roghayyeh Saeedi ◽  
Nasim Rezaeimanesh ◽  
Mohammad Ali Sahraian ◽  
Abdorreza Naser Moghadasi
Keyword(s):  
Multiple Sclerosis ◽  
Cognitive Impairment ◽  
Cognitive Disorders ◽  
Clinical Information ◽  
Immunosuppressive Drugs ◽  
Cognitive Disorder ◽  
P Value ◽  
Information Processing Speed ◽  
Cross Sectional ◽  
The Relationship

Objective: The prevalence of cognitive impairment in multiple sclerosis (MS) is significant and it is estimated that 40% to 70% of patients with MS suffer from this impairment. COVID-19 is also a new infectious disease. The symptoms of this disease, which include fever, shortness of breath, and cough, can be mild to severe and can even lead to death. Due to the use of immunosuppressive drugs by Patients with MS, they might be at greater risk of catching COVID-19. Thus, patients with MS may be more afraid of catching the virus. One of the important factors is the relationship between cognitive deficit and the increase in patients' fear of COVID-19. The aim of this study was to assess the relationship between fear of catching COVID-19 and cognitive impairment in patients with MS. Method: This cross-sectional study was conducted at the MS Clinic, Sina hospital, Tehran University of Medical Sciences, Tehran, Iran. Our participants in this project were Patients with MS who were over 18 years old and had no history of other neurological and psychiatric diseases. In addition to obtaining demographic and clinical information, we measured the fear of catching the COVID 2019 via Fear of COVID-19 Scale (FCV-19S), which is 7-item questionnaire. We also used Multiple Sclerosis Neuro Psychological Screening Questionnaire (MSNQ) to assess memory and information processing speed in Patients with MS. Results: After adjustment for age, gender, disease duration, highest level of education, MS type, and EDSS in linear regression model, as well as the MSNQ total score and fear score of catching coronavirus, the results demonstrated a significant positive correlation with P value of 0.00 and β: 0.024. Conclusion: The present study showed a direct relationship between cognitive disorder and level of fear regarding COVID-19. Patients with more cognitive disorders were more afraid of COVID-19.

Evaluación Cognitiva Montreal y consumo de alcohol: Un diagnóstico descriptivo del deterioro cognitivo en estudiantes universitarios de Durango, México

2019 ◽  
pp. 28-38
Author(s):  
Karla Liliana Pérez-Sosa ◽  
Edgar Felipe Lares-Bayona
Keyword(s):  
Cognitive Impairment ◽  
Alcohol Consumption ◽  
Cognitive Functions ◽  
Toxic Substance ◽  
Female Gender ◽  
Diagnostic Tools ◽  
Cross Sectional ◽  
Probabilistic Study ◽  
The Central Nervous System ◽  
The Relationship

Alcohol is a toxic substance associated with acute and chronic disorders affecting the Central Nervous System and significantly altering brain function. Objective: To determine the relationship between cognitive impairment and alcohol consumption in university students of the Juárez University of the State of Durango. Methodology: It is a cross-sectional, descriptive, comparative, non-probabilistic study, for convenience. A database was designed on the results obtained in a clinical interview on alcohol consumption and the application of the Montreal Cognitive Assessment (MoCA) test. Contribution: The evaluation of cognitive functions show similar results, the male sex presented a better score in Attention and the female one in Orientation. More involvement was identified in the Deferred Memory functions in both groups. In relation to alcohol consumption, the cognitive functions evaluated show lower levels. The female gender was more evident cognitive impairment in relation to alcohol consumption being statistically significant (p <0.025). Alcohol consumption is a risky behavior that deserves to be recognized by the main actors about neurocognitive effects. Alcohol consumption prevention programs and cognitive diagnostic tools are appropriate strategies to reduce risk behaviors in mental health.

HUBUNGAN INTELEGENSI DENGAN PERILAKU NERS TINGKAT II STIKES SANTA ELISABETH MEDAN

2016 ◽  
Vol 1 (1) ◽  
pp. 21-30
Author(s):  
Imelda Derang
Keyword(s):  
Student Nurses ◽  
Sampling Technique ◽  
P Value ◽  
Test Results ◽  
Cross Sectional ◽  
Intelligence Level ◽  
Level Ii ◽  
Study Population ◽  
Cross Sectional Design ◽  
The Relationship

Intelligence is the ability to apply the knowledge and experiences that have been gained into the effort tasks are challenging and flexible book. Behaviour is an action that involves aspects of affective, cognitive, and psychomotor. Goal: This study aims to determine the relationship between the behavior of student nurses intelligence level II STIKes Santa Elisabeth Medan. Method: This study uses correlation with cross sectional design. The study population was all students / i Ners Level II STIKes Santa Elisabeth Medan as 65. The samples used were 65 respondents, the sampling technique in this research is using purposive sampling. The instrument of this study using questionnaire and observation sheets by using product moment test person. Result: Intelligence students as many as 30 people (46.2%) classified as having an average level of intelligence. A total of 32 people (49.2%) classified as well-behaved students. Person product moment test results obtained p value = 0.172 where a significant level of p> 0.05 so that this value proves that the absence of a relationship between the behavior of student nurses intelligence level II STIKes Santa Elisabeth Medan. Conclusion: Recommended for institutions, motivating students in balancing the behavior and intelligence. 

scholarly journals THE RELATIONSHIP BETWEEN OCCUPATIONAL STRESSORS AND COPING STRATEGIES IN NURSING TECHNICIANS

2016 ◽  
Vol 25 (4) ◽  
Author(s):  
Sandra de Souza Pereira ◽  
Carla Araujo Bastos Teixeira ◽  
Emilene Reisdorfer ◽  
Mariana Verderoce Vieira ◽  
Edilaine Cristina da Silva Gherardi-Donato ◽  
...  
Keyword(s):  
Coping Strategies ◽  
Exploratory Research ◽  
Occupational Stressors ◽  
Cross Sectional ◽  
Coping Scale ◽  
Cross Sectional Design ◽  
Quantitative Descriptive ◽  
And Coping ◽  
Nursing Professionals ◽  
The Relationship

ABSTRACT This is a quantitative, descriptive and exploratory research, with cross-sectional design that investigated the stressors experienced by nursing technicians working in general hospital and identified the coping strategies most used by them. The sample contained 310 participants. A sociodemographic questionnaire and the Ways of Coping Scale were used. For the analysis we used descriptive statistics and calculated the Cronbach's alpha. 60% of professionals used the strategies focused on the problem; 57.4% attributed their stress to working conditions, 26.8% to relationships in the workplace, 5.5% to the lack of reward at work and only 0.6% to problems personal. We conclude that strategies focused on the problems were the most used, indicating an approximation of the stressor in order to fix it. The identified stressors indicate the need for planning, stimulating and recognizing nursing professionals.

scholarly journals The relationship between Internet use and self-concept clarity: A systematic review and meta-analysis

2021 ◽  
Vol 15 (2) ◽  
Author(s):  
Cristina Elena Petre
Keyword(s):  
Systematic Review ◽  
Internet Use ◽  
Meta Analysis ◽  
Self Concept ◽  
The Internet ◽  
Inclusion Criteria ◽  
Cross Sectional ◽  
Self Evaluation ◽  
Cross Sectional Design ◽  
The Relationship

There are three hypotheses regarding the relationship between Self-Concept Clarity (SCC) and Internet use. It was argued that Internet use: 1) decreases SCC, 2) increases SCC, 3) does not relate with SCC. The present study, in the form of a systematic and meta-analytic synthesis, aimed to explore: a) the extent empirical evidence can support each hypothesis; b) how Internet use-SCC relationship was addressed across studies; c) the intensity of the Internet use –SCC relationship; d) potential moderators. Twenty-one studies (N = 8,910) met the inclusion criteria for the systematic review (i.e., being quantitative, written in English, concerned with Internet use -SCC relationship) and 11 studies (N = 3,298) met the additional criteria for meta-analysis (i.e., being correlational, using self-evaluation instruments, quantifying general Internet use and including the information needed to calculate the meta-analysis specific indicators). Results emphasized that all three hypotheses are plausible, as distinct dimensions of Internet use related differently with SCC. However, the conclusions were limited by the extensive use of cross-sectional design. For general Internet use and SCC relationship the overall effect was -0.350, p < .01. Some moderators were significant: cultural background, Internet operationalization, age homogeneity, participants rewarding. This paper outlines the complexity of SCC – Internet relationship and underlines some of the gaps that should be further addressed. Implications and limits of the study (e.g., publication bias, excluded outcomes in the meta-analysis or possible omission of moderators) are discussed.

scholarly journals HUBUNGAN TINGKAT PENGETAHUAN IBU DAN DUKUNGAN SUAMI TERHADAP KEBERHASILAN PEMBERIAN ASI EKSKLUSIF

2019 ◽  
Vol 2 (1) ◽  
pp. 5
Author(s):  
Eka Putri Primasari
Keyword(s):  
Breast Milk ◽  
Exclusive Breastfeeding ◽  
Statistical Test ◽  
P Value ◽  
Test Results ◽  
Cross Sectional ◽  
Level Of Knowledge ◽  
Cross Sectional Design ◽  
The Relationship ◽  
Low Rate

Abstract: Breast milk is the best food for babies, especially in the first month of life. Breast milk contains all nutrients to build and provide the energy needed by the baby. The low rate of breastfeeding is a threat to child development. Several factors related to the success of exclusive breastfeeding are the level of knowledge of the mother and husband's support. The purpose of this study was to determine the relationship between the level of knowledge of mothers and husband's support  towards the success of exclusive breastfeeding in Lubuk Kilangan Puskesmas in 2017. This study was analytical with a cross sectional design. The population in this study amounted to 153 respondents. A sample of 31 respondents obtained by simple ramdom sampling. Data were analyzed bivariate. The statistical test results obtained p-value = 0,000. It can be concluded that there is a relationship between the knowledge of mothers about exclusive breastfeeding and husband's support for the success of exclusive breastfeeding.

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