Internet platforms as a structural element of education - educational and organizational function

2016 ◽  
Author(s):  
Ewa Lubina
Keyword(s):  
Structural Element ◽  
Organizational Function

Bioavailability of naringenin chalcone in humans after ingestion of cherry tomatoes

2020 ◽  
Vol 90 (5-6) ◽  
pp. 411-416 ◽  
Author(s):  
Carina Kolot ◽  
Ana Rodriguez-Mateos ◽  
Rodrigo Feliciano ◽  
Katharina Bottermann ◽  
Wilhelm Stahl
Keyword(s):  
Plasma Levels ◽  
Average Concentration ◽  
Biologically Active ◽  
Thiol Groups ◽  
Structural Element ◽  
Active Molecule ◽  
Reactive Center ◽  
Average Maximum ◽  
Alpha Beta ◽  
Cherry Tomatoes

Abstract. Chalcones are a type of flavonoids characterized by an α-β unsaturated structural element which may react with thiol groups to activate pathways such as the Nrf2-Keap-1 system. Naringenin chalcone is abundant in the diet but little is known about its bioavailability. In this work, the bioavailability of naringenin chalcone from tomatoes was investigated in a group of healthy men (n=10). After ingestion of 600 grams of tomatoes providing a single dose of 17.3 mg naringenin chalcone, 0.2 mg of naringenin, and 195 mg naringin plasma levels of free and conjugated naringenin and naringenin chalcone (glucuronide and sulfate) were analyzed by UHPLC-QTOF-MS at 0.5, 1, 3, and 6 h post-consumption. Plasma levels of conjugated naringenin increased to about 12 nmol/L with a maximum at about 3 h. Concentrations of free naringenin hardly elevated above baseline. Plasma levels of free and conjugated naringenin chalcone significantly increased. A maximum of the conjugated chalcone was reached at about 3 h after ingestion with an average concentration of about 0.5 nmol/L. No free chalcone was detectable at baseline but low amounts of the unconjugated compound could be detected with an average maximum of 0.8 nmol/L at about 1 h after ingestion. The data demonstrate that naringenin chalcone is bioavailable in humans from cherry tomatoes as a dietary source. However, availability is poor and intramolecular cyclisation as well as extended metabolism likely contribute to the inactivation of the reactive alpha-beta unsaturated reactive center as well as the excretion of the biologically active molecule, respectively.

Theoretical and experimental research on slip and uplift of the timber-concrete composite beam

BioResources ◽  
2020 ◽  
Vol 15 (3) ◽  
pp. 7079-7099
Author(s):  
Jianying Chen ◽  
Guojing He ◽  
Xiaodong (Alice) Wang ◽  
Jiejun Wang ◽  
Jin Yi ◽  
...  
Keyword(s):  
Differential Equations ◽  
Deformation Theory ◽  
Concrete Slab ◽  
Theoretical Calculations ◽  
Structural Element ◽  
Structural Efficiency ◽  
Theoretical Investigations ◽  
New Type ◽  
Interlayer Slip ◽  
Good Agreement

Timber-concrete composite beams are a new type of structural element that is environmentally friendly. The structural efficiency of this kind of beam highly depends on the stiffness of the interlayer connection. The structural efficiency of the composite was evaluated by experimental and theoretical investigations performed on the relative horizontal slip and vertical uplift along the interlayer between composite’s timber and concrete slab. Differential equations were established based on a theoretical analysis of combination effects of interlayer slip and vertical uplift, by using deformation theory of elastics. Subsequently, the differential equations were solved and the magnitude of uplift force at the interlayer was obtained. It was concluded that the theoretical calculations were in good agreement with the results of experimentation.

Redefinisi Fungsi Desa dalam Manga Naruto dan Bande Dessinée Astérix: Sebuah Kajian Komparasi Budaya Populer

Metahumaniora ◽  
2017 ◽  
Vol 7 (3) ◽  
pp. 293
Author(s):  
Tania Intan
Keyword(s):  
Popular Culture ◽  
Rural Environment ◽  
Cultural Comparison ◽  
Structural Element ◽  
Legal Entity ◽  
Bande Dessinee ◽  
Spare Time ◽  
Popular Medium ◽  
The World ◽  
The Village

AbstrakSecara alamiah, manusia membutuhkan sarana untuk mengisi waktu luangnyasetelah bekerja keras. Satu media yang murah, mudah dijangkau, dan digemari oleh semuakalangan di seluruh dunia adalah cerita bergambar atau komik yang merupakan bagiandari budaya populer. Pada umumnya, karya paraliteratur-visual ini memang bersifat fiktifdan hanya merupakan peniruan dari kenyataan yang digambarkan secara berlebihan(grotesque). Namun demikian, di dalam komik, sering ditemukan nilai-nilai kehidupanyang bersifat universal dan abadi sehingga dianggap layak sebagai bahan kajian budaya.Naruto, salah satu manga Jepang, dan Astérix, bande dessinée dari Prancis, akan ditelitisebagai representasi dunia Timur dan Barat. Latar sebagai unsur struktural dalam karyakaryafiksi ini ternyata juga menunjukkan kesamaan mendasar, yaitu keberadaan desasebagai tempat hidup para tokohnya. Dalam tulisan ini, akan dibahas pemaknaan lainterhadap lingkungan rural tersebut, yang memiliki andil dalam pembentukan karakterpara tokoh dari kedua komik. Metode kajian komparasi budaya akan digunakan denganpenerapan teori-teori yang relevan. Penelitian singkat ini bertujuan untuk melengkapistudi mengenai komik yang belum banyak dilakukan di Indonesia.Kata kunci: Desa, komik, Naruto, Astérix, Komparasi BudayaAbstractNaturally, humans need a way to fill their spare time after working hard. Acheap, accessible and popular medium by all circles around the world is a picture or comicstory, which is part of popular culture. McCloud (1993:7) defines comics as drawings andembossed symbols in a particular order, aimed at providing information or achievingaesthetic responses from the reader. In general, this visual-paraliterature work isindeed fictitious and merely an imitation of grotesque reality. However, in the comics, itis often found that values of life that are universal and eternal so comics are consideredappropriate as a material of cultural studies. Naruto, one of the Japanese manga, andAstérix, the bande dessinée of France, are examined as a representation of the East andWest. The background as a structural element in these works of fiction also shows the basicsimilarity of the existence of the village as the place of life of the characters. According toKartohadikoesoemo (1984:16), the village is a legal entity, in which a ruling society livesits own government. In this paper, other meanings of the rural environment, which hascontributed in the character formation of the characters from both comics are discussed.The method of cultural comparative is used with the application of relevant theories. Thisbrief study aims to complete the study of comics which is still very limited in Indonesia.Keywords: Village, Comic, Naruto, Astérix, Cultural Comparison

The features of viability and social adaptation of patients who underwent revisional hip replacement

2020 ◽  
pp. 60-63
Author(s):  
Elena Senina
Keyword(s):  
Empirical Study ◽  
Hip Replacement ◽  
Individual Characteristic ◽  
Social Adaptation ◽  
Structural Element ◽  
Postoperative Rehabilitation ◽  
Physical Recovery ◽  
Research Institute

The author analyzes the category of viability as a structural element of social adaptation of patients who underwent revisional hip replacement. Considering the process of postoperative rehabilitation, the author focuses on viability as an individual characteristic of patients, which determines the effectiveness of physical recovery and social adaptation after hip replacement. The article observes the results of an empirical study conducted on the basis of Saratov Research Institute of Traumatology and Orthopedics of Minzdrav of Russia, aimed at studying the criteria of viability and social viability of adaptation and social adaptation.

STRUCTURAL RELIABILITY ANALYSIS BASED ON P-BOXES

2020 ◽  
Vol 92 (6) ◽  
pp. 51-58
Author(s):  
S.A. SOLOVYEV ◽  
Keyword(s):  
Probability Distribution ◽  
Reliability Analysis ◽  
Structural Reliability ◽  
Epistemic Uncertainty ◽  
Random Variable ◽  
Strength Criterion ◽  
Structural Elements ◽  
Structural Element ◽  
Limit States ◽  
Distribution Shape

The article describes a method for reliability (probability of non-failure) analysis of structural elements based on p-boxes. An algorithm for constructing two p-blocks is shown. First p-box is used in the absence of information about the probability distribution shape of a random variable. Second p-box is used for a certain probability distribution function but with inaccurate (interval) function parameters. The algorithm for reliability analysis is presented on a numerical example of the reliability analysis for a flexural wooden beam by wood strength criterion. The result of the reliability analysis is an interval of the non-failure probability boundaries. Recommendations are given for narrowing the reliability boundaries which can reduce epistemic uncertainty. On the basis of the proposed approach, particular methods for reliability analysis for any structural elements can be developed. Design equations are given for a comprehensive assessment of the structural element reliability as a system taking into account all the criteria of limit states.

TAKING INTO CONSIDERATION OF THE MULTIPLE MODE OF THE FUNCTIONING AND CHARACTERISTICS OF THE CONTROL IN RELIABILITY MODELS OF REPLACEMENT TIME SYSTEMS

2019 ◽  
Author(s):  
Iryna Kononova
Keyword(s):  
A Priori ◽  
Telecommunication System ◽  
Structural Element ◽  
Reliability Models ◽  
Quick Recovery ◽  
Reliability Indicators ◽  
A Priori Uncertainty ◽  
Control Of Parameters ◽  
Time Systems ◽  
Time Reserve

The article evaluates the reliability indicators of telecommunication system equipment, which can be represented by multi-mode objects of continuous and episodic use with a time reserve operating under conditions of a priori uncertainty. Particular attention is paid to consideration of the process of functioning of the system with a replenished time reserve. The telecommunication system includes an object represented by one structural element and used in different modes of operation. In each mode, the object can be used continuously or episodically (the object performs tasks that occur at random times), herewith only a certain part of its equipment is operating. The restoration of the facility's operation in each mode is based on the "quick" recovery scheme ("quick" recovery means that the repair time is much less than the average working time of the element between failures). Also, some cases of the transition of an object from one mode to another are considered, and the control system operates according to the method of sequential control of parameters. In this case, the system, after waiting mode, begins to analyze the first parameter of the monitored complex, then the second and so on. After analyzing the parameters, the system enters the waiting mode. These calculated ratios allow for a comprehensive assessment of the reliability of telecommunication equipment, taking into account the totality of the main factors that significantly affect the reliability of the equipment in real conditions of operation, make it possible to solve important practical problems which arise from the improvement of existing equipment and development of existing equipment.

scholarly journals Chromosomal Lesion Suppression and Removal in Escherichia coli via Linear DNA Degradation

Genetics ◽  
2003 ◽  
Vol 163 (4) ◽  
pp. 1255-1271 ◽  
Author(s):  
Anabel Miranda ◽  
Andrei Kuzminov
Keyword(s):  
Dna Degradation ◽  
Dna Helicase ◽  
Structural Element ◽  
E Coli ◽  
Linear Dna ◽  
Replication Factory ◽  
Low Copy Number ◽  
Chromosomal Lesion ◽  
Recbcd Enzyme

Abstract RecBCD is a DNA helicase/exonuclease implicated in degradation of foreign linear DNA and in RecA-dependent recombinational repair of chromosomal lesions in E. coli. The low viability of recA recBC mutants vs. recA mutants indicates the existence of RecA-independent roles for RecBCD. To distinguish among possible RecA-independent roles of the RecBCD enzyme in replication, repair, and DNA degradation, we introduced wild-type and mutant combinations of the recBCD chromosomal region on a low-copy-number plasmid into a ΔrecA ΔrecBCD mutant and determined the viability of resulting strains. Our results argue against ideas that RecBCD is a structural element in the replication factory or is involved in RecA-independent repair of chromosomal lesions. We found that RecBCD-catalyzed DNA degradation is the only activity important for the recA-independent viability, suggesting that degradation of linear tails of σ-replicating chromosomes could be one of the RecBCD’s roles. However, since the weaker DNA degradation capacity due a combination of the RecBC helicase and ssDNA-specific exonucleases restores viability of the ΔrecA ΔrecBCD mutant to a significant extent, we favor suppression of chromosomal lesions via linear DNA degradation at reversed replication forks as the major RecA-independent role of the RecBCD enzyme.

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