scholarly journals The Influence of Comprehensive Nursing Intervention on the Negative Emotion and Quality of Life of Patients with Pulmonary Tuberculosis

2013 ◽  
Vol 2 ◽  
pp. 14
Author(s):  
Wenfang Fei
Keyword(s):  
Quality Of Life ◽  
Social Support ◽  
Health Education ◽  
Pulmonary Tuberculosis ◽  
Negative Emotion ◽  
Intervention Group ◽  
Nursing Intervention ◽  
Control Group ◽  
Quality Of Life Scale

<p><strong>Objective:</strong> The study discussed the influence of comprehensive nursing intervention on the negative emotion and quality of life of patients with pulmonary tuberculosis. <strong>Method:</strong> 118 patients with pulmonary tuberculosis were collected in our department, who were randomly allocated to the two groups. In the intervention group (59 cases), in addition to conventional nursing, the patients also received the comprehensive nursing intervention based on health education, psychological guidance, cognitive-behavioral change and encouragement of social support. The control group (59 cases) received conventional nursing. The differences of negative emotion and quality of life between two groups were analyzed by the negative emotion subscale and quality of life scale (WHONQOL-BREF) in the Positive and Negative Affect Scale (PANAS). <strong>Results:</strong> The quality of life in the intervention group was significantly higher than the control group after intervention, and the negative emotion was significant lower than the control group. <strong>Conclusion: </strong>The comprehensive nursing intervention, based on health education, psychological guidance and encouragement of social support, could significantly reduce the negative emotion of patients with pulmonary tuberculosis, improved the quality of life.</p>

scholarly journals Effect of “Modular” Nursing Intervention on the Therapeutic Effect of Ranoxifene on Postmenopausal Osteoporosis

2020 ◽  
Vol 185 ◽  
pp. 03022
Author(s):  
Yang Guo ◽  
XiaoJie Sun ◽  
Miao Tai ◽  
Fang Liu ◽  
XiaoWei Liu ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Patient Satisfaction ◽  
Postmenopausal Osteoporosis ◽  
Negative Emotion ◽  
Intervention Group ◽  
Life Quality ◽  
Nursing Intervention ◽  
Routine Care ◽  
Control Group

the purpose of this study was to explore the effect of “modular” nursing intervention on Ranoxifene in the treatment of patients with postmenopausal osteoporosis. A total of 108 patients with postmenopausal osteoporosis who were accepted by the Department of Orthopaedics in our hospital were selected as the research objects. According to the random number table method and they were divided into two groups (the intervention group and the control group), 54 cases in each group. The control group was given routine care, while the other was given “modular” interventional care. The patient satisfaction, adverse mood changes and quality of life changes in the two groups was observed in the treatment. The results of this study showed that the nursing satisfaction of the patients in the intervention group was significantly higher than that in the control group; however, the negative emotion of the two groups of patients after care were lower than that before the care, and the degree of reduction in the intervention group was significantly higher than that of the control group; the life quality of patient in the two groups was improved than before nursing, and the degree of improvement in the intervention group was significantly higher than that in the control group. Therefore, the clinical application of Raloxifene in the treatment of postmenopausal osteoporosis patients with “modular” nursing intervention can improve patient satisfaction, relieve negative emotions, and improve quality of life.

scholarly journals Rehabilitation Nursing Intervention Can Improve Dysphagia and Quality of Life of Patients Undergoing Radiotherapy for Esophageal Cancer

2021 ◽  
Vol 2021 ◽  
pp. 1-6
Author(s):  
Xiange Zeng ◽  
Ling Li ◽  
Wenjing Wang ◽  
Lihui Zhu
Keyword(s):  
Quality Of Life ◽  
Esophageal Cancer ◽  
Intervention Group ◽  
Life Quality ◽  
Nursing Intervention ◽  
Control Group ◽  
Swallowing Function ◽  
Acute Radiation Injury ◽  
Random Number Table

Objective. To seek the improvement of rehabilitation nursing intervention on dysphagia and quality of life of patients with esophageal cancer undergoing radiotherapy. Methods. A total of 109 patients with esophageal cancer undergoing radiotherapy were selected as research objects. According to the random number table, they were separated into the control group (CG) and intervention group (IG), with 45 cases in CG and 64 cases in IG. In CG, patients were given routine nursing intervention, while those in IG were given rehabilitation nursing intervention. After intervention, the degree of acute radiation injury and the improvement of swallowing function were observed to compare the self-nursing ability, quality of life, and incidence of complications between the two groups. Results. The degree of injury in CG was heavier than that in IG. The improvement of swallowing function in IG was better than that in CG. The scores of self-nursing ability and life quality in IG were higher than those in CG, with statistically significant differences ( p < 0.05 ). The incidence of complications in IG was obviously lower than that in CG ( p < 0.05 ). Conclusion. Rehabilitation nursing intervention can ameliorate dysphagia, improve the quality of life, and reduce the incidence of complications for patients with esophageal cancer undergoing radiotherapy. It is worthy of clinical application.

scholarly journals Health Education Through a Campaign and mHealth to Enhance Knowledge and Quality of Life Among Patients With Chronic Kidney Disease in Bangladesh: Protocol for a Randomized Controlled Trial (Preprint)

2021 ◽  
Author(s):  
Mohammad Habibur Rahman Sarker ◽  
Michiko Moriyama ◽  
Harun Ur Rashid ◽  
Md Moshiur Rahman ◽  
Mohammod Jobayer Chisti ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Chronic Kidney Disease ◽  
Randomized Controlled Trial ◽  
Kidney Disease ◽  
Health Education ◽  
Controlled Trial ◽  
Intervention Group ◽  
Control Group ◽  
Randomized Controlled

BACKGROUND Despite the growing burden of chronic kidney disease (CKD), disease knowledge and understanding are still lacking, especially in Bangladesh. OBJECTIVE The aim of this study was to evaluate the outcome of a health education intervention in order to enhance knowledge, health-related quality of life (QOL), and motivation regarding healthy lifestyles among rural and periurban adults suffering from CKD. METHODS A parallel-group (1:1) randomized controlled trial is ongoing in the Mirzapur subdistrict, Bangladesh, where two groups of patients with CKD are being compared. Patients aged 18 years and over with CKD (stages 1-3) were enrolled in November 2020. Patients were randomly allocated into either the intervention group (n=63) or the control group (n=63). The control group received usual treatment, while the intervention group received health education through a CKD campaign facilitated by a nephrologist and via mHealth (ie, periodic mobile phone calls) from community health workers. Both groups were followed up for a period of 6 months. The primary endpoint is patients’ increased knowledge measured using the Chronic Kidney Disease Knowledge Questionnaire. The secondary endpoints are improved QOL measured using the standardized EuroQol 5-Dimension 5-Level (EQ-5D-5L) questionnaire as well as improvements in the levels of blood pressure, BMI, serum creatinine, fasting blood sugar, hemoglobin, cholesterol, high-density lipoprotein cholesterol, triglyceride, serum uric acid, blood urea nitrogen, and albumin to creatinine ratio. RESULTS Enrollment of participants began in November 2020; the intervention and follow-up were completed in May 2021. We enrolled 126 patients in the study. Patients’ mean ages were 57.97 (SD 15.03) years in the control group and 57.32 (SD 14.37) years in the intervention group. There were 45 out of 63 (71%) females in the control group and 38 out of 63 (60%) females in the intervention group. In addition, there were 38 out of 63 (60%) literate patients in the control group and 33 out of 63 (52%) literate patients in the intervention group. CONCLUSIONS It is expected that a combined approach, incorporating both a CKD campaign and mHealth, for health education may be an effective tool for increasing knowledge and improving QOL among patients with CKD. CLINICALTRIAL ClinicalTrials.gov NCT04094831; https://clinicaltrials.gov/ct2/show/NCT04094831 INTERNATIONAL REGISTERED REPORT DERR1-10.2196/30191

scholarly journals M185. THE EFFECTS OF GROUP ARTS THERAPY BASED ON EMOTION MANAGEMENT TRAINING ON THE EMOTIONAL EXPRESSION, ALEXITHYMIA, DEPRESSION AND QUALITY OF LIFE IN PATIENTS WITH SCHIZOPHRENIA

2020 ◽  
Vol 46 (Supplement_1) ◽  
pp. S206-S207
Author(s):  
Eunsung Lim ◽  
Sung-Yong Park ◽  
Seung-Ho Jang ◽  
Won-Myong Bahk ◽  
Young-Joon Kwon ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Emotional Expression ◽  
Positive Emotion ◽  
Negative Emotion ◽  
Management Training ◽  
Emotion Management ◽  
Control Group ◽  
General Psychopathology ◽  
Quality Of Life Scale

Abstract Background The objective of this study was to investigate the effects of group arts therapy based on emotion management training on emotional expression, positive emotion and negative emotion, alexithymia, depression and quality of life in patients with schizophrenia. Methods 24 of 160 in-patients with schizophrenia, according to DSM-IV from H Mental Health Hospital, were randomly assigned to either an experimental or control group. Each group were consisting of 12 patients. Group arts therapy was conducted on the experimental group twice a week, 60 minutes per session, for a total of 16 sessions, while the control group was left untreated. The following scales were used for assessment: Berkeley Expressivity Questionnaire (BEQ), Positive Affective and Negative Affect Schedule (PANAS), Toronto Alexithymia Scale-Korean vesion (TAS-20K), Depression Scale for Schizophrenia (K-CDSS), Positive and Negative Syndrome Scale (PANSS), and Schizophrenia Quality of Life Scale (SQLS-R4K). Independent t-test was conducted to confirm the homogeneity, and to find the effects of group arts therapy, Repeated measures ANOVA was conducted to confirm the differences for scores of each scales regarding groups, measuring timing, and also the interaction between groups and measuring timing by pre, post and follow-up test. Results The result of this study are as follows. First, total score, expressivity factors and impulse strength factors of emotional expressivity were significantly increased after group arts therapy compared to the control group. Second, positive emotion was significantly increased and negative emotion was significantly decreased after group integrative therapy compared to the control group. Third, total score, difficulty identifying feelings of Alexithymia were significantly decreased after group arts therapy compared to the control group. Fourth, depression was significantly decreased after group integrative arts therapy compared to the control group. Fifth, negative syndromes and general psychopathology were significantly decreased after group arts therapy compared to the control group. Sixth, quality of life was significantly increased after group arts therapy compared to the control group. Discussion The group arts therapy have significantly improved the emotional expression, positive emotion, negative emotion and Alexithymia in patients with schizophrenia and also improved negative syndromes, general psychopathology, depression and quality of life. These result suggest that group arts therapy based on emotion management training could be a useful intervention for emotional disturbance treatment for in patients with schizophrenia.

Effects of health education based on mobile platform on cognitive function and quality of life of children with pneumonia

2021 ◽  
Vol 7 (6) ◽  
pp. 6529-6539
Author(s):  
Yang Lu ◽  
Xi Ying
Keyword(s):  
Quality Of Life ◽  
Cognitive Function ◽  
Health Education ◽  
Clinical Symptoms ◽  
Nursing Intervention ◽  
Mobile Platform ◽  
Control Group ◽  
Observation Group ◽  
Early Recovery

Objective: To explore the effects of health education based on mobile platform on cognitive function and quality of life of children with pneumonia. Methods: Eighty parents with pneumonia admitted to our hospital from March 2018 to March 2020 were selected as the research subjects. The parents of the control group received routine nursing intervention, and the parents of the observation group received health education intervention based on the mobile platform. After nursing, the nursing effect of the two groups was compared. The cognitive function and quality of life of the two groups were compared after nursing. The time of cough, dyspnea, shortness of breath and lung rales were compared between the two groups. The incidence of rash, abdominal pain, dizziness and headache and parents' satisfaction with nursing were compared between the two groups. Results: Compared with the control group, the nursing effective rate of the observation group was significantly increased (P<0.05). The scores of cognitive function and quality of life in observation group were significantly higher than those in control group (P<0.05). Compared with the control group, the disappearance time of clinical symptoms in the observation group was significantly decreased (P<0.05). The satisfaction of parents in the observation group was significantly higher than that in the control group (P<0.05). Conclusion: Health education based on mobile platform can effectively improve the cognitive function and quality of life of children with pneumonia, contribute to the early recovery of children, and has high clinical application value.

Analysis of the Effect of Advanced Nursing on the Quality of Life and the Prevention of Complications in Patients with Breast Cancer Undergoing PICC Chemotherapy

2021 ◽  
Vol 7 (5) ◽  
pp. 1558-1563
Author(s):  
Xiuzhen Hu ◽  
Qun Yang ◽  
Zhengyun Wang ◽  
Xuyun Hu
Keyword(s):  
Breast Cancer ◽  
Quality Of Life ◽  
Negative Emotion ◽  
Nursing Intervention ◽  
Psychological Status ◽  
Control Group ◽  
Study Group ◽  
Clinical Value ◽  
Significant Difference

Objective: To investigate the effect of advanced nursing on the quality of life and the prevention of complications in patients with breast cancer undergoing PICC (Peripherally Inserted Central Catheter) chemotherapy. Methods: From January 2017 to January 2020, 98 patients with breast cancer undergoing PICC chemotherapy in our hospital were divided into control group and study group by random sampling. The patients were given routine nursing and advanced nursing intervention on the basis of routine nursing. The psychological status, complications and quality of life of the patients were compared. Results: There was no significant difference in HAMA, HAMD score and QLQ-30 score before nursing (P > 0.05). The scores of HAMA and HAMD in the study group after nursing were lower than those in the control group (P < 0.05), the scores of QLQ-30 were higher than those in the control group (P < 0.05), and the complication rate was lower than that in the control group (P < 0.05). Conclusion: The intervention of advanced nursing mode in patients with breast cancer treated with PICC chemotherapy can effectively alleviate the influence of negative emotion on chemotherapy, reduce the occurrence of complications and improve the quality of life. This mode has high clinical value.

scholarly journals Clinical Efficacy of Treating Endometrial Cancer with Xiaoaiping Tablets under Comprehensive Nursing Intervention and Their Effect on Quality of Life

2021 ◽  
Vol 2021 ◽  
pp. 1-9
Author(s):  
Juan Wang ◽  
Qingyan Liu ◽  
Jianping Li ◽  
Dan Nie ◽  
Daiying Zhang
Keyword(s):  
Quality Of Life ◽  
Endometrial Cancer ◽  
Clinical Efficacy ◽  
Negative Emotion ◽  
Remission Rate ◽  
Depression Scale ◽  
Nursing Intervention ◽  
Control Group ◽  
Experimental Group

Objective. To explore the clinical efficacy of treating endometrial cancer with Xiaoaiping tablets under comprehensive nursing intervention and their effect on quality of life. Methods. The clinical data of 120 endometrial cancer patients treated at the Affiliated Hospital of Southwest Medical University from February 2019 to February 2020 were retrospectively analyzed, and the patients were split into the experimental group and the control group according to their admission order, with 60 cases each. Conventional treatment and Xiaoaiping tablet regimen were received by all patients, those in the control group accepted the general nursing, and those in the experimental group accepted the comprehensive nursing intervention for 12 months, so as to compare their clinical efficacy, quality of life (Functional Assessment of Cancer Therapy, FACT), negative emotion scores (Hospital Anxiety and Depression Scale, HAD), and Medical Coping Modes Questionnaire (MCMQ) scores between the two groups. Results. No statistical differences in the patients’ general information between the two groups were observed ( P > 0.05 ); compared with the control group after nursing, the experimental group obtained a significantly higher objective remission rate (80.0%), significantly higher disease control rate (90.0%) ( P < 0.05 ), significantly better QOL ( P < 0.001 ), significantly lower negative emotion scores ( P < 0.001 ), and significantly better MCMQ scores ( P < 0.001 ). Conclusion. Adopting Xiaoaiping tablets under comprehensive nursing intervention can improve the negative emotions of patients with endometrial cancer, enhance their confidence in medical treatment, present better efficacy, and obviously promote their QOL. Therefore, comprehensive nursing intervention should be promoted and applied in practice.

scholarly journals Health Education Through a Campaign and mHealth to Enhance Knowledge and Quality of Life Among Patients With Chronic Kidney Disease in Bangladesh: Protocol for a Randomized Controlled Trial

10.2196/30191 ◽  
2021 ◽  
Vol 10 (11) ◽  
pp. e30191
Author(s):  
Mohammad Habibur Rahman Sarker ◽  
Michiko Moriyama ◽  
Harun Ur Rashid ◽  
Md Moshiur Rahman ◽  
Mohammod Jobayer Chisti ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Chronic Kidney Disease ◽  
Randomized Controlled Trial ◽  
Kidney Disease ◽  
Health Education ◽  
Controlled Trial ◽  
Intervention Group ◽  
Control Group ◽  
Randomized Controlled

Background Despite the growing burden of chronic kidney disease (CKD), disease knowledge and understanding are still lacking, especially in Bangladesh. Objective The aim of this study was to evaluate the outcome of a health education intervention in order to enhance knowledge, health-related quality of life (QOL), and motivation regarding healthy lifestyles among rural and periurban adults suffering from CKD. Methods A parallel-group (1:1) randomized controlled trial is ongoing in the Mirzapur subdistrict, Bangladesh, where two groups of patients with CKD are being compared. Patients aged 18 years and over with CKD (stages 1-3) were enrolled in November 2020. Patients were randomly allocated into either the intervention group (n=63) or the control group (n=63). The control group received usual treatment, while the intervention group received health education through a CKD campaign facilitated by a nephrologist and via mHealth (ie, periodic mobile phone calls) from community health workers. Both groups were followed up for a period of 6 months. The primary endpoint is patients’ increased knowledge measured using the Chronic Kidney Disease Knowledge Questionnaire. The secondary endpoints are improved QOL measured using the standardized EuroQol 5-Dimension 5-Level (EQ-5D-5L) questionnaire as well as improvements in the levels of blood pressure, BMI, serum creatinine, fasting blood sugar, hemoglobin, cholesterol, high-density lipoprotein cholesterol, triglyceride, serum uric acid, blood urea nitrogen, and albumin to creatinine ratio. Results Enrollment of participants began in November 2020; the intervention and follow-up were completed in May 2021. We enrolled 126 patients in the study. Patients’ mean ages were 57.97 (SD 15.03) years in the control group and 57.32 (SD 14.37) years in the intervention group. There were 45 out of 63 (71%) females in the control group and 38 out of 63 (60%) females in the intervention group. In addition, there were 38 out of 63 (60%) literate patients in the control group and 33 out of 63 (52%) literate patients in the intervention group. Conclusions It is expected that a combined approach, incorporating both a CKD campaign and mHealth, for health education may be an effective tool for increasing knowledge and improving QOL among patients with CKD. Trial Registration ClinicalTrials.gov NCT04094831; https://clinicaltrials.gov/ct2/show/NCT04094831 International Registered Report Identifier (IRRID) DERR1-10.2196/30191

scholarly journals Effectiveness of Health Promotional Strategies on Quality of Life among Spouse of Alcoholics in Selected Communities of Dakshina Kannada District, India

2020 ◽  
Author(s):  
PJ Shiji ◽  
Neetha Kamath ◽  
Supriya Hegde
Keyword(s):  
Quality Of Life ◽  
Health Education ◽  
Demographic Variable ◽  
Intervention Group ◽  
Control Group ◽  
The Family ◽  
Post Test ◽  
Promotional Strategies ◽  
And Control

Introduction: Alcoholism is a major problem in developing countries like India. Alcoholism affects not only the individual but also his family and the society. Spouses of alcoholics are among those who suffer the maximum consequences of alcoholism and its effects. Aim: To find the effect of health promotional strategies (Yoga and Health education) on Quality of Life (QOL) of the spouse of alcoholics. Materials and Methods: Quasi experimental pre-test post-test control design was adopted. A total of 330 men were administered the Alcohol Use Disorders Identification Test (AUDIT) tool to screen for alcoholics through house to house survey, of which 279 men who scored in the range of 8-15 AUDIT score were considered as alcoholics. Their spouses were selected as study participants (who met the sampling criteria) and subjects were randomly allocated to intervention group (132) and control group (147) through simple randomised sampling. The data was gathered by using WHOQOL-BREF tool to assess the QOL; initially pre-test QOL was assessed, followed by individual health education (45 minutes) and yoga (15 minutes) once a week for 3 consecutive weeks and post-test was done during fourth week for intervention (127) and control groups (142). There were five dropouts in post-test from each group due to health problems, migration and no cooperation from the family for the intervention. Independent t-test was performed by using SPSS version 18.0 to determine effectiveness of health promotion strategies on QOL scores between the intervention and control group and chi-square test was used to find the association between post-intervention QOL scores and selected demographic variable at p<0.05 level of significance. Results: QOL scores in all four domains in the intervention group showed that there was an increase before and after the interventions. On comparing the mean differences between QOL scores post-test in intervention and control group, calculated t-value was (34.04) and the difference was highly statistically significant at p<0.001** showing that health promotional strategies were effective in improving QOL among spouse of alcoholics. There was a significant association between post-test intervention QOL scores of subjects and selected variables such as primary decision maker (p=0.002*) of the family and history of domestic violence (p=0.030*). Conclusion: The study findings suggest that adopting health promotional strategies such as yoga can help the spouses of alcoholics to improve their QOL.

scholarly journals Mobile Breast Cancer e-Support Program for Chinese Women With Breast Cancer Undergoing Chemotherapy (Part 2): Multicenter Randomized Controlled Trial (Preprint)

2017 ◽  
Author(s):  
Jiemin Zhu ◽  
Lyn Ebert ◽  
Xiangyu Liu ◽  
Di Wei ◽  
Sally Wai-Chi Chan
Keyword(s):  
Breast Cancer ◽  
Quality Of Life ◽  
Social Support ◽  
Health Outcomes ◽  
Self Efficacy ◽  
Controlled Trial ◽  
Intervention Group ◽  
Support Program ◽  
Control Group

BACKGROUND Women undergoing chemotherapy for the treatment of breast cancer have frequently reported unmet supportive care needs. Moreover, easily accessible and innovative support is lacking. OBJECTIVE The purpose of this trial was to determine the effectiveness of an app-based breast cancer e-support program to address women’s self-efficacy (primary outcome), social support, symptom distress, quality of life, anxiety, and depression. Secondary objectives included exploring the association between women’s health outcomes and the breast cancer e-support usage data. METHODS A multicenter, single-blinded, randomized controlled trial was conducted. A total of 114 women with breast cancer, who were commencing chemotherapy and were able to access internet through a mobile phone, were recruited in the clinics from 2 university-affiliated hospitals in China. Women were randomized either to the intervention group (n=57) receiving breast cancer e-support plus care as usual or the control group (n=57) receiving care as usual alone. The health care team and research assistants collecting data were blinded to the women’s group allocation. Bandura’s self-efficacy theory and the social exchange theory guided the development of the breast cancer e-support program, which has 4 components: (1) a Learning forum, (2) a Discussion forum, (3) an Ask-the-Expert forum, and (4) a Personal Stories forum. Moderated by an experienced health care professional, the breast cancer e-support program supported women for 12 weeks covering 4 cycles of chemotherapy. Health outcomes were self-assessed through paper questionnaires in clinics at baseline before randomization (T0), after 3 (T1), and 6 months (T2) of follow-ups. RESULTS Fifty-five participants in the intervention group and 49 in the control group completed the follow-up assessments (response rate: 91.2%). During the 12-week intervention, the log-in frequency ranged from 0 to 774 times (mean 54.7; SD 131.4; median 11; interquartile range, IQR 5-27), and the total usage duration ranged from 0 to 9371 min (mean 1072.3; SD 2359.5; median 100; IQR 27-279). Repeated measures multivariate analysis of covariance (intention-to-treat) found that breast cancer e-support + care as usual participants had significant better health outcomes at 3 months regarding self-efficacy (21.05; 95% CI 1.87-40.22; P=.03; d=0.53), symptom interference (−0.73; 95% CI −1.35 to −.11; P=.02; d=−0.51), and quality of life (6.64; 95% CI 0.77-12.50; P=.03, d=0.46) but not regarding social support, symptom severity, anxiety, and depression compared with care as usual participants. These beneficial effects were not sustained at 6 months. Spearman rank-order correlation showed that the breast cancer e-support usage duration was positively correlated with self-efficacy (r=.290, P=.03), social support (r=.320, P=.02), and quality of life (r=.273, P=.04) at 3 months. CONCLUSIONS The breast cancer e-support program demonstrated its potential as an effective and easily accessible intervention to promote women’s self-efficacy, symptom interference, and quality of life during chemotherapy. CLINICALTRIAL Australian New Zealand Clinical Trials Registry (ANZCTR): ACTRN12616000639426; www.ANZCTR.org.au/ACTRN12616000639426.aspx (Archived by Webcite at http://www.webcitation.org/6v1n9hGZq)

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