scholarly journals Treatment of arterial hypertension in patients with diabetes mellitus and nephropathy: current potentialities of renin-angiotensin-aldosterone system block

2003 ◽  
Vol 9 (6) ◽  
pp. 191-195
Author(s):  
O. D. Ostroumova ◽  
A. A. Zykova ◽  
A. M. Batutina
Keyword(s):  
Diabetes Mellitus ◽  
Renal Failure ◽  
Chronic Renal Failure ◽  
Arterial Hypertension ◽  
Antihypertensive Agents ◽  
Cardiovascular Complications ◽  
Angiotensin Ii Receptor ◽  
Hypertensive Nephropathy ◽  
Patients With Diabetes ◽  
End Stage

Diabetes mellitus and arterial hypertension are major risk factors of cardiovascular complications. Diabetic nephropathy is the most common cause of end-stage chronic renal failure in the world; next is hypertensive nephropathy. Microalbuminuria is the earliest clinical marker of renal dysfunction. The basic clinical significance of microalbuminuria is that it is an independent risk factor of both end-stage chronic renal failure and cardiovascular complications. Controlling blood pressure with antihypertensive agents in patients with diabetes mellitus ensures diminished microalbuminuria and retards the development of chronic renal failure. Angiotensin II receptor blockers and angiotensin-converting enzyme (ACE) inhibitors are essential drugs for the treatment of patients with diabetes mellitus and nephropathy. A combination of these two classes of drugs offers new prospects for nephroprotection in this group of patients.

scholarly journals Hand osteomyelitis in arterial calcification, diabetes mellitus and end-stage renal failure: a comparison of 210 cases over 12 years

2021 ◽  
pp. 175319342098187
Author(s):  
Matthew Wyman ◽  
Dallan Dargan ◽  
Jennifer Caddick ◽  
Victoria Giblin
Keyword(s):  
Diabetes Mellitus ◽  
Renal Failure ◽  
Disease Free Survival ◽  
Arterial Calcification ◽  
Level Of Evidence ◽  
Free Survival ◽  
End Stage Renal Failure ◽  
Patients With Diabetes ◽  
End Stage ◽  
Steal Syndrome

We present 210 patients with hand osteomyelitis in 246 rays over 12 years, including detailed analysis of 29 patients in this cohort with digital artery calcification evident on plain X-ray. Overall 71 patients had diabetes mellitus and/or end-stage renal failure, including 28 of 29 patients with calcification. In the calcification group, 17 patients had ipsilateral arteriovenous fistulae, five had steal syndrome and 15 had digital ulceration or skin necrosis. Compared with 181 controls, patients with calcification had more affected bones, polymicrobial infections, surgical procedures, phalanges and digits amputated and had higher mortality at 1 year (12 of 29) and 5 years (20 of 29), as a result of comorbidities. Absence of calcification in 43 patients with diabetes and/or end-stage renal failure was associated with better outcomes on all the above parameters. Early amputation to maximize disease-free survival may be appropriate for patients with hand osteomyelitis and arterial calcification. Level of evidence: IV

scholarly journals The Study of Biochemical Markers in Chronic Renal Failure Patients in Pre- and Post-Haemodialysis

2021 ◽  
Vol 53 (03) ◽  
pp. 259-264
Author(s):  
Mohammed Abed Jawad ◽  
Keyword(s):  
Diabetes Mellitus ◽  
Lipid Peroxidation ◽  
Renal Failure ◽  
Chronic Renal Failure ◽  
Group Method ◽  
Control Group ◽  
Renal Markers ◽  
Patients With Diabetes ◽  
History Of ◽  
Notable Increase

Background: The current research is designed to investigate alterations in lipid peroxidation (malondialdehyde - MDA) and renal markers (urea and creatinine) in patients of chronic renal failure (CRF) as compared to the control group. Method: The study included 55 subjects, who were separated into two groups: control group, which included 15 healthy members with no history of systematic illness; and patients group, which included 40 patients with CRF divided into four groups “Non: CRF patients without any accompanied disease, DM: CRF patients with diabetes mellitus, HT: CRF patients with hypertension, and HT + DM: CRF patients with diabetes mellitus and hypertension”. Results: The findings reveal that there is a notable increase in serum concentration of MDA, urea, and creatinine, in patients group as compared to the control group. Conclusion: In all chronic renal failure patients with or without any accompanying disease, lipid peroxidation is present in pre- and post-haemodialysis patients as well as patients with CRF have high levels of urea and creatinine compared with healthy groups.

The clinical and instrumental rationale for the choice of therapy of arterial hypertension in the patients presenting with diabetes mellitus

2013 ◽  
Vol 58 (6) ◽  
pp. 8-12
Author(s):  
I. P. Tatarchenko ◽  
N. V. Pozdnyakova ◽  
A. G. Mordovina
Keyword(s):  
Diabetes Mellitus ◽  
Arterial Hypertension ◽  
Diastolic Heart Failure ◽  
Angiotensin Ii Receptor ◽  
Vasomotor Function ◽  
Patients With Diabetes ◽  
Hemodynamic Characteristics ◽  
Arterial Endothelium ◽  
Choice Of Therapy

Cardiovascular disorders are the main cause of high disability and mortality rates among the patients with diabetes mellitus. The objective of the present work was to estimate the clinical and hemodynamic characteristics during the treatment of arterial hypertension with the use of olmesartan (hypertension/angiotensin II receptor antagonist, ARA) in the patients with type 2 diabetes mellitus suffering diastolic heart failure. The study included 56 patients (26 men and 30 women) of the mean age 58.2±5.3 years. They were given a course of olmesartan (cardosal) therapy 40 weeks in duration. This treatment was shown to result in positive dynamics of structural and geometric characteristics of the left ventricle and its diastolic function in conjunction with the improvement of the vasomotor function of arterial endothelium.

Alexithymic Characteristics of Bulimia Nervosa in Diabetes Mellitus with End-Stage Renal Disease

1997 ◽  
Vol 81 (2) ◽  
pp. 627-633 ◽  
Author(s):  
Isao Fukunishi
Keyword(s):  
Diabetes Mellitus ◽  
Renal Failure ◽  
Bulimia Nervosa ◽  
Prevalence Rate ◽  
Diabetic Patients ◽  
Related Factors ◽  
End Stage Renal Failure ◽  
Patients With Diabetes ◽  
Stage Renal Disease ◽  
End Stage

This study examined the clinical characteristics including stress-related factors of eating disorders in a sample of 312 diabetic patients with end-stage renal failure. The prevalence rate of bulimia nervosa was 5.1% (16 of 312 patients). The 16 patients with bulimia nervosa were 8 men and 8 women over 58 years old. Looking at the subjects by cause of end-stage renal failure, those with diabetes mellitus exhibited significantly higher prevalence rate of bulimia nervosa than two nondiabetic groups (diabetes 10%; nephritis 1.6%; others 1.9%). As for the association of bulimia nervosa and stress-related factors, end-stage renal failure patients with diabetes who exhibited bulimia nervosa showed significantly higher scores on a measure of alexithymia. These results suggest that, when liaison psychiatrists see diabetic patients with end-stage renal failure who exhibit bulimia nervosa, they should pay close attention to stress-related symptoms including alexithymia.

scholarly journals ALBUMIN AND HEMOGLOBIN VALUE IN CHRONIC RENAL FAILURE (CRF) PATIENTS WITH DIABETES AND NON-DIABETES

2018 ◽  
Vol 2 (2) ◽  
pp. 253
Author(s):  
Diyah Candra Anita
Keyword(s):  
Diabetes Mellitus ◽  
Renal Failure ◽  
Chronic Renal Failure ◽  
Nutritional Status ◽  
Sampling Method ◽  
Historical Background ◽  
Measuring Instruments ◽  
Cross Sectional ◽  
Patients With Diabetes ◽  
Larger Sample

Introduction. Malnutrition is a common problem in patients with chronic renal failure (CRF) with Diabetes Mellitus and Non-Diabetes Mellitus. Assessments of nutritional status in CRF patients are required to measure some important parameters including serum albumin and hemoglobin. This study aimed to fi gure out the differences of nutritional status between CRF patients with diabetes mellitus and without diabetes mellitus in the inpatient unit of PKU Muhammadiyah Hospital Yogyakarta, by examining the levels of albumin and hemoglobin serum. Methods. This study applied cross sectional method of which measuring instruments were patients’ medical records of laboratory tests. This research used accidental sampling method involving 30 patients as samples. Result. The results of independent t-test showed that there was no signifi cant differences between the levels of albumin (p = 0.917) and hemoglobin (p = 0.168) between the group of non DM CRF patients and CRF patients with  M. Discussion. Therefore, further research should be performed by using a larger sample size as well as considering patients’ historical background of hemodialysis treatment.Keywords: Diabetes Mellitus (DM), Chronic Renal Failure (CRF), albumin, hemoglobin

scholarly journals Diabetic retinopathy: a tool for cardiovascular risk stratification

2020 ◽  
Vol 22 (5) ◽  
pp. 455-460
Author(s):  
Angelo Avogaro ◽  
Gian Paolo Fadini
Keyword(s):  
Diabetes Mellitus ◽  
Bone Marrow ◽  
Renal Failure ◽  
Diabetic Retinopathy ◽  
Cardiovascular Risk ◽  
Microvascular Complications ◽  
Cardiovascular Complications ◽  
Cross Sectional ◽  
Patients With Diabetes ◽  
Diabetic Microvascular Complications

Randomized, cross-sectional, and prospective studies have demonstrated that microvascular complications in patients with diabetes are not only the cause of blindness, renal failure and non-traumatic amputations, but also powerful predictors of cardiovascular complications. The pathophysiology of diabetic microvascular complications is determined by several factors including epigenetic modifications, and reduced release of circulating progenitor cells by the bone marrow. Identifying microvascular complications, in particular retinopathy, increases the ability to stratify patients in terms of cardiovascular risk. There may no longer be a rational to consider microangiopathy and macroangiopathy as entirely separate entities, but they should most likely be viewed as a continuum of the widespread vascular damage determined by diabetes mellitus.

scholarly journals Differences in Arteriovenous Fistula Maturation between Diabetes Mellitus and Non-Diabetes Mellitus in Chronic Renal Failure Patients in Padang

2021 ◽  
Vol 6 (1) ◽  
pp. 1287-1291
Author(s):  
Richard Santosa ◽  
Raflis Rustam ◽  
Vendry Rivaldy
Keyword(s):  
Diabetes Mellitus ◽  
Renal Failure ◽  
Chronic Renal Failure ◽  
Arteriovenous Fistula ◽  
Kidney Failure ◽  
Chronic Kidney Failure ◽  
Fistula Surgery ◽  
Arteriovenous Fistulas ◽  
Significant Difference ◽  
Patients With Diabetes

Background: Arteriovenous fistula (AVF) is the preferred vascular access for hemodialysis (HD). Several factors can affect AVF maturity, such as diabetes. This study aims to determine the differences in the maturation of arteriovenous fistulas between diabetes mellitus and non-diabetes mellitus in patients with chronic kidney failure in Padang. Methods: This was a comparative cross-sectional study of patients with chronic kidney failure who underwent arteriovenous fistula surgery in Padang. The sampling technique in this study was consecutive sampling. The analysis was carried out using statistical analysis according to the existing data scale and using SPSS software. Results: This study involved 46 patients with chronic kidney failure who underwent arteriovenous fistula surgery in Padang, of which 23 patients with diabetes mellitus and 23 patients with non-diabetes mellitus. The diameter of the arteriovenous fistula between diabetes mellitus and non-diabetes mellitus in patients with chronic renal failure had a significant difference (p<0.05). There was no significant difference in flow, depth, and maturation of arteriovenous fistulas in patients with diabetes mellitus and non-diabetes mellitus with chronic renal failure. Conclusion: There is no difference in the maturation of arteriovenous fistula between patients with diabetes mellitus and non-diabetes mellitus

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