scholarly journals The Study of Biochemical Markers in Chronic Renal Failure Patients in Pre- and Post-Haemodialysis

2021 ◽  
Vol 53 (03) ◽  
pp. 259-264
Author(s):  
Mohammed Abed Jawad ◽  
Keyword(s):  
Diabetes Mellitus ◽  
Lipid Peroxidation ◽  
Renal Failure ◽  
Chronic Renal Failure ◽  
Group Method ◽  
Control Group ◽  
Renal Markers ◽  
Patients With Diabetes ◽  
History Of ◽  
Notable Increase

Background: The current research is designed to investigate alterations in lipid peroxidation (malondialdehyde - MDA) and renal markers (urea and creatinine) in patients of chronic renal failure (CRF) as compared to the control group. Method: The study included 55 subjects, who were separated into two groups: control group, which included 15 healthy members with no history of systematic illness; and patients group, which included 40 patients with CRF divided into four groups “Non: CRF patients without any accompanied disease, DM: CRF patients with diabetes mellitus, HT: CRF patients with hypertension, and HT + DM: CRF patients with diabetes mellitus and hypertension”. Results: The findings reveal that there is a notable increase in serum concentration of MDA, urea, and creatinine, in patients group as compared to the control group. Conclusion: In all chronic renal failure patients with or without any accompanying disease, lipid peroxidation is present in pre- and post-haemodialysis patients as well as patients with CRF have high levels of urea and creatinine compared with healthy groups.

Biochemical Analysis of Vitreous Humor in Postmortal Diagnosis of Renal Failure

10.12737/2726 ◽  
2013 ◽  
Vol 20 (4) ◽  
pp. 47-49
Author(s):  
Терёхина ◽  
N. Terekhina ◽  
Акимов ◽  
Pavel Akimov
Keyword(s):  
Diabetes Mellitus ◽  
Molecular Weight ◽  
Renal Failure ◽  
Serum Creatinine ◽  
Biochemical Analysis ◽  
Vitreous Humor ◽  
Control Group ◽  
Patients With Diabetes ◽  
Maximum Content

The content of medium molecular weight peptides and creatinine in serum and vitreous humor from 48 corpses of people suffering from diabetes mellitus during his lifetime and 27 without this disease, formed the control group, were investigated. The presence of renal failure among patients with diabetes mellitus and in the control group was, respectively, in 20 and 15 persons was revealed. The content of serum creatinine in cadaver blood without renal failure was more than 2-2,5 - folds in comparative with living people and was not more than 240 μηΊθΙ/L. The content of serum medium molecular weight peptides in control group was not more than 2,8 g/L, and in the group of diabetes mellitus without renal failure - 2,9 g/L. The obtained results are analogical with data of living people accordingly literature sources. Direct correlation between the content of creatinine, medium molecular weight peptides and vitreous humor and serum are estimated. The maximum content of creatinine and medium molecular weight peptides in vitreous humor were, respectively, 110 μΓηοΙ/L and 0,5 g/L. The values extreme graduated in presents of renal failure as in serum, as in vitreous humor. Thus, in postmortal period appropriate to determine the vitreous humor creatinine and medium molecular weight peptides content for the diagnosis of renal failure.

A study of haptoglobin phenotypes in patients with chronic renal failure

2003 ◽  
Vol 40 (6) ◽  
pp. 680-683 ◽  
Author(s):  
Samir Awadallah ◽  
Mawieh Hamad
Keyword(s):  
Renal Failure ◽  
Chronic Renal Failure ◽  
Polyacrylamide Gel Electrophoresis ◽  
Reflux Nephropathy ◽  
Control Group ◽  
Chronic Glomerulonephritis ◽  
Polycystic Kidney ◽  
Patients With Diabetes ◽  
Hardy Weinberg Equilibrium ◽  
Blood Specimens

Background: This study has investigated the association between haptoglobin (Hp) polymorphism and the occurrence of chronic renal failure (CRF) in Jordanians. Methods: Blood specimens were collected from 159 patients with CRF resulting from various predisposing conditions and from 200 healthy unrelated controls. Hp phenotyping was conducted using polyacrylamide gel electrophoresis. Results: The Hp 2-2 phenotype was over-represented in CRF patients in general (0.547), patients with hypertension (0.622) and patients with diabetes mellitus (0.633). The Hp 2-1 phenotype was over-represented in patients with chronic glomerulonephritis (0.549) and patients with reflux nephropathy (0.445). In patients with polycystic kidney disease (PKD), only Hp 2-1 and Hp 2-2 were detected, occurring at a frequency of 0.214 and 0.786, respectively. The frequency of Hp 2 allele in PKD patients was 0.893 compared with 0.706 in the control group. Hp-type distribution was in agreement with the expectations of a population in Hardy-Weinberg equilibrium in all groups except for the hypertensive patients. Conclusions: Haptoglobin homozygosity seems to represent a possible risk factor for CRF in hypertensive, diabetic and PKD patients; Hp heterozygosity may lead to chronic glomerulonephritis.

scholarly journals ALBUMIN AND HEMOGLOBIN VALUE IN CHRONIC RENAL FAILURE (CRF) PATIENTS WITH DIABETES AND NON-DIABETES

2018 ◽  
Vol 2 (2) ◽  
pp. 253
Author(s):  
Diyah Candra Anita
Keyword(s):  
Diabetes Mellitus ◽  
Renal Failure ◽  
Chronic Renal Failure ◽  
Nutritional Status ◽  
Sampling Method ◽  
Historical Background ◽  
Measuring Instruments ◽  
Cross Sectional ◽  
Patients With Diabetes ◽  
Larger Sample

Introduction. Malnutrition is a common problem in patients with chronic renal failure (CRF) with Diabetes Mellitus and Non-Diabetes Mellitus. Assessments of nutritional status in CRF patients are required to measure some important parameters including serum albumin and hemoglobin. This study aimed to fi gure out the differences of nutritional status between CRF patients with diabetes mellitus and without diabetes mellitus in the inpatient unit of PKU Muhammadiyah Hospital Yogyakarta, by examining the levels of albumin and hemoglobin serum. Methods. This study applied cross sectional method of which measuring instruments were patients’ medical records of laboratory tests. This research used accidental sampling method involving 30 patients as samples. Result. The results of independent t-test showed that there was no signifi cant differences between the levels of albumin (p = 0.917) and hemoglobin (p = 0.168) between the group of non DM CRF patients and CRF patients with  M. Discussion. Therefore, further research should be performed by using a larger sample size as well as considering patients’ historical background of hemodialysis treatment.Keywords: Diabetes Mellitus (DM), Chronic Renal Failure (CRF), albumin, hemoglobin

scholarly journals Differences in Arteriovenous Fistula Maturation between Diabetes Mellitus and Non-Diabetes Mellitus in Chronic Renal Failure Patients in Padang

2021 ◽  
Vol 6 (1) ◽  
pp. 1287-1291
Author(s):  
Richard Santosa ◽  
Raflis Rustam ◽  
Vendry Rivaldy
Keyword(s):  
Diabetes Mellitus ◽  
Renal Failure ◽  
Chronic Renal Failure ◽  
Arteriovenous Fistula ◽  
Kidney Failure ◽  
Chronic Kidney Failure ◽  
Fistula Surgery ◽  
Arteriovenous Fistulas ◽  
Significant Difference ◽  
Patients With Diabetes

Background: Arteriovenous fistula (AVF) is the preferred vascular access for hemodialysis (HD). Several factors can affect AVF maturity, such as diabetes. This study aims to determine the differences in the maturation of arteriovenous fistulas between diabetes mellitus and non-diabetes mellitus in patients with chronic kidney failure in Padang. Methods: This was a comparative cross-sectional study of patients with chronic kidney failure who underwent arteriovenous fistula surgery in Padang. The sampling technique in this study was consecutive sampling. The analysis was carried out using statistical analysis according to the existing data scale and using SPSS software. Results: This study involved 46 patients with chronic kidney failure who underwent arteriovenous fistula surgery in Padang, of which 23 patients with diabetes mellitus and 23 patients with non-diabetes mellitus. The diameter of the arteriovenous fistula between diabetes mellitus and non-diabetes mellitus in patients with chronic renal failure had a significant difference (p<0.05). There was no significant difference in flow, depth, and maturation of arteriovenous fistulas in patients with diabetes mellitus and non-diabetes mellitus with chronic renal failure. Conclusion: There is no difference in the maturation of arteriovenous fistula between patients with diabetes mellitus and non-diabetes mellitus

Polyuria

2015 ◽  
Author(s):  
Hugo Farne ◽  
Edward Norris-Cervetto ◽  
James Warbrick-Smith
Keyword(s):  
Diabetes Mellitus ◽  
Renal Failure ◽  
Urinary Tract ◽  
Chronic Renal Failure ◽  
Urine Output ◽  
Urinary Frequency ◽  
Patient Will ◽  
Chronic Urinary Retention ◽  
Pain Frequency ◽  
History Of

In both polyuria and high urinary frequency the patient will be passing urine more often than before. But in polyuria, patients will pass abnormally large volumes of clear urine each time. In urinary frequency, the volume voided each time will be normal or reduced. The only way of knowing objectively whether this is the case is by collecting a 24-hour urine sample (>3 L = polyuria). As this is usually impractical outside of hospital, one must rely on the patient’s recall, with the caveat that many patients find it difficult to estimate urine output. In the history, then, ask them whether they feel they are passing a larger volume every time they go to the toilet. Remember that it is important to be as sure as you can that you are dealing with polyuria and not urinary frequency or nocturia, as the differential diagnoses are quite distinct. Chronic renal failure and hypercalcaemia (e.g. due to bone metastases) cause polyuria by inducing nephrogenic diabetes insipidus. Similarly, steroids and Cushing’s syndrome can cause polyuria by causing diabetes mellitus. • Temporal pattern of urine output (number of times in the day and at night), especially nocturia. At night, the kidneys concentrate urine in order to retain fluid (as intake is zero), removing the need to urinate during sleep. Thus nocturia (in the absence of other causes of nocturia, e.g. benign prostatic hyperplasia (BPH)) is often one of the earliest signs of a loss of concentrating ability. This symptom makes primary polydipsia less likely. • Fatigue, weight loss, recurrent infections. All can be features of diabetes mellitus. • Lower urinary tract symptoms (LUTS), e.g. frequency, urgency, hesitancy, terminal dribbling, incomplete voiding. These symptoms indicate pathology in the bladder or the outflow tract, e.g. prostatism in men, detrusor instability and prolapse in women. Not strictly speaking polyuria. • Pain, frequency, change in urine colour and smell. These are all symptoms suggestive of a urinary tract infection (UTI), which would cause increased frequency but not polyuria. • Past medical history. Look for any history of renal problems or conditions that may precipitate chronic renal failure (e.g. vasculitides, hypertension, chronic urinary retention).

STATUS NUTRISI PASIEN GAGAL GINJAL KRONIS DENGAN DIABETES MELLITUS DAN NON-DIABETES MELLITUS

2016 ◽  
Vol 5 (2) ◽  
pp. 92-98
Author(s):  
Diyah Candra Anita
Keyword(s):  
Diabetes Mellitus ◽  
Renal Failure ◽  
Chronic Renal Failure ◽  
Nutritional Status ◽  
Medical Records ◽  
Descriptive Research ◽  
Measuring Devices ◽  
Laboratory Results ◽  
Patients With Diabetes ◽  
Test Result

Background:Malnutrition is a common problem in chronic renal failure (CRF) patients with or without Diabetes Mellitus (DM). An assessment of nutritional status in CRF patients is encouraged to see the level of its severity. The general parameters for assessing nutritional status are serum albumin and hemoglobin. Objective:The objective of this research was to investigate the differences on thenutritional status of CRF patients with Diabetes Mellitus (DM) compared to those without DM at PKU Muhammadiyah Hospital Yogyakarta. Methods:This was a comparative descriptive research applying accidental sampling and was conducted for 6 months (June-November 2014). The main measuring devices were patients’ medical records and laboratory results of albumin and hemoglobin levels. Sampleof this study consisted of 30 respondents. Independent t-test was applied to analyze the differences of albumin and hemoglobin levels in both groups. Result:The test result showed that the albumin (p=0.917) and hemoglobin levels (p=0.168) of CRF patients without DM and that of CRF patients with DM were not significantly different. Conclusion:CRF patients with and without DM had low level of albumin and hemoglobin. Nurses shouldbe more careful in regulating fluidbalance to reduce pulmonary edema. Keywords:Chronic Renal Failure (CRF), diabetes mellitus(DM), albumin, hemoglobin

FAKTOR-FAKTOR YANG BERHUBUNGAN DENGAN KEJADIAN GAGAL GINJAL KRONIK PADA PASIEN USIA < 45 TAHUN DI RUANG HEMODIALISA RSUD INDRAMAYU

2017 ◽  
Vol 5 (1) ◽  
pp. 48-56
Author(s):  
Wayunah . ◽  
Neneng Ratnanengsih Puspitasari ◽  
Fatikhatul Jannah
Keyword(s):  
Diabetes Mellitus ◽  
Renal Failure ◽  
Chronic Renal Failure ◽  
P Value ◽  
Chi Square ◽  
Study Approach ◽  
Failure Event ◽  
Chi Square Test ◽  
History Of

Gagal ginjal kronik merupakan suatu kondisi dimana ginjal mengalami penurunan fungsi yang terjadi secara progresif dan irreversible. Banyak faktor yang dapat menyebabkan GGK pada pasien usia < 45 tahun. Tujuan penelitian ini adalah untuk mengetahui faktor-faktor yang berhubungan dengan kejadian GGK pada pasien usia < 45 tahun. Penelitian ini dilakukan dengan pendekatan case study. Sampel dipilih dengan tekhnik counsecutive sampling, dengan jumlah 98 responden. Alat pengumpul data dalam penelitian ini menggunakan kuesioner. Analisis data bivariat yang digunakan dalam penelitian ini adalah uji chi square. Hasil penelitian diketahui faktor yang berhubungan adalah faktor riwayat penyakit diabetes mellitus (p value = 0,002). Sedangkan faktor yang tidak berhubungan adalah faktor zat kimia (p value = 0,295), faktor kurang asupan cairan (p value = 0,366), faktor riwayat hipertensi (p value = 0,518) dan faktor riwayat obstruksi saluran kemih (p value = 0,312). Simpulan dalam penelitian ini faktor yang berhubungan adalah diabates mellitus dan faktor yang tidak berhubungan adalah konsumsi zat kimia, kurang asupan cairan, riwayat penyakit hipertensi dan riwayat penyakit obstruksi saluran kemih. Saran dalam penelitian ini ditujukan kepada perawat untuk meningkatkan edukasi kepada masyarakat tentang pencegahan terjadinya GGK. Abstrak Chronic Renal Failure is a condition that decreasing kidney function, occurning progresive and irreversible. Many factors causes CRF in patiens aged < 45 years. Purpose of this study was to determine the factors associated with the occurrence of CRF in patiens age < 45 years.This research was conducted with case study approach. Samples selected with counsecutive technique sampling with 98 respondents. Data collection, this study using a questionnaire. The bivariae data analysis used in this study is the chi square test. The results is known factors associacted with in a diabetes mellitus of history factor (p value = 0,002) while factor unrelated chemical substances is a factor ( p value = 0,925), less intake of fluids factor (p value = 0,366), hypertension of history factor ( p value = 0,518) and history of obstruction of tract urinary factor (p value = 0,312). Conclusions in this research that there is a relationship between the factors of history of diabetes mellitus with chronic renal failure event in patients aged < 45 years. Suggestions in this study was shown to the nurse to increase public education about the prevention of the occurance of CRF.

scholarly journals STATUS NUTRISI PASIEN GAGAL GINJAL KRONIS DENGAN DIABETES MELLITUS DAN NON-DIABETES MELLITUS

2019 ◽  
Vol 5 (2) ◽  
pp. 92-98
Author(s):  
Diyah Candra Anita
Keyword(s):  
Diabetes Mellitus ◽  
Renal Failure ◽  
Chronic Renal Failure ◽  
Nutritional Status ◽  
Medical Records ◽  
Descriptive Research ◽  
Measuring Devices ◽  
Laboratory Results ◽  
Patients With Diabetes ◽  
Test Result

Background:Malnutrition is a common problem in chronic renal failure (CRF) patients with or without Diabetes Mellitus (DM). An assessment of nutritional status in CRF patients is encouraged to see the level of its severity. The general parameters for assessing nutritional status are serum albumin and hemoglobin. Objective:The objective of this research was to investigate the differences on thenutritional status of CRF patients with Diabetes Mellitus (DM) compared to those without DM at PKU Muhammadiyah Hospital Yogyakarta. Methods:This was a comparative descriptive research applying accidental sampling and was conducted for 6 months (June-November 2014). The main measuring devices were patients’ medical records and laboratory results of albumin and hemoglobin levels. Sampleof this study consisted of 30 respondents. Independent t-test was applied to analyze the differences of albumin and hemoglobin levels in both groups. Result:The test result showed that the albumin (p=0.917) and hemoglobin levels (p=0.168) of CRF patients without DM and that of CRF patients with DM were not significantly different. Conclusion:CRF patients with and without DM had low level of albumin and hemoglobin. Nurses shouldbe more careful in regulating fluidbalance to reduce pulmonary edema. Keywords: Chronic Renal Failure (CRF), diabetes mellitus(DM), albumin, hemoglobin

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