scholarly journals THE VIBRATION DISEASE IN WORKERS OF THE AIRCRAFT ENTERPRISE: FACTORS OF THE FORMATION, CLINICAL MANIFESTATIONS, SOCIAL-PSYCHOLOGICAL FEATURES (DYNAMIC FOLLOWING-UP)

2018 ◽  
Vol 97 (10) ◽  
pp. 915-920 ◽  
Author(s):  
Marina V. Kuleshova ◽  
V. A. Pankov ◽  
M. P. Dyakovich ◽  
V. S. Rukavishnikov ◽  
N. V. Slivnitsyna ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Emotional State ◽  
Clinical Manifestations ◽  
Health Related Quality ◽  
Local Vibration ◽  
Vibration Disease ◽  
Study Results ◽  
Related Quality ◽  
Health Related

Introduction. The vibration disease takes one of the leading places in the structure of the occupational morbidity in the Irkutsk region, its specific weight accounted of 21.1-35.9% of all newly revealed cases of occupational diseases in different years. The purpose of the study is to investigate the socio-psychological features and manifestations of the vibration disease clinical syndromes in local vibration-exposed employees in the dynamic of observation. Material and methods. The assessment of working conditions of employees in the aircraft enterprise, a coherent dynamic clinical and sociopsychological examination in employees with the occupational disease which continuing their work was carried out. Results. Working conditions have not been changed; the levels of the occupational and labor process factors have remained the same in the dynamic. Clinical manifestations of vibration disease and neurosensory hearing loss, which is the second (accompanying) occupational disease, were shown to be aggravated in patients continuing to work in contact with local vibration. A significant prevalence of diseases of the musculoskeletal system and the circulatory system has been revealed. High levels of the personal and situational anxiety, hypochondriacal traits, instability of emotional state, the rigid stereotype of behavior-oriented to caring about physical well-being are registered in patients. A reduction of health-related quality of life scores characterizing the role of physical and emotional functioning has been established, that indicates the limitations in the performance of daily work due to the deterioration of the emotional state. Discussion. The significant prevalence of diseases of the musculoskeletal and circulatory systems in vibration disease patients is associated with both the irritating effect of the actual vibration and the severity of the work process and significant physical overloads. The study results of the psycho-emotional status, the health-related quality of life in vibration disease patients allow assuming a significant effect of the pain syndrome on the emotional state, decrease of the health-related quality of life, which is consistent with the other authors’ studies. Conclusion. The study results show that it is necessary to remove workers from contact with vibration if the initial manifestations of vibration disease appear. Also, it is necessary to revise approaches to the secondary prevention of vibration disease, which should be aimed at preserving residual work capacity and medical and psychological adaptation of patients.

Health-related quality of life measures in routine clinical care: Can FACT-Fatigue help to assess the management of fatigue in cancer patients?

2009 ◽  
Vol 25 (01) ◽  
pp. 90-96 ◽  
Author(s):  
Maria-Jose Santana ◽  
Heather-Jane Au ◽  
Melina Dharma-Wardene ◽  
Joanne D. Hewitt ◽  
David Dupere ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Cancer Patients ◽  
Clinical Care ◽  
Health Related Quality ◽  
Routine Clinical Care ◽  
Study Results ◽  
Related Quality ◽  
Health Related

Objectives:Fatigue is the most common symptom reported by cancer patients. The inclusion of health-related quality of life (HRQL) measures in routine clinical care of cancer patients may improve the management of fatigue. The primary objective of this study is to provide evidence on the magnitude of change in fatigue subscale scores using the Functional Assessment of Cancer Therapy-Fatigue (FACT-F) that is clinically important.Methods:Consecutive patients with advanced primary lung cancer attending a Canadian tertiary care cancer and, prior to undergoing palliative chemotherapy, were enrolled in the study. Patients completed a battery of questionnaires [FACT-F, Qualitative Patients Self-report of Fatigue Level (QPSRF)] at baseline, follow-up and 2 weeks after their final cycle of chemotherapy. Clinicians assessed the patients using the Eastern Cooperative Oncology Group (ECOG) Performance Status Scale at baseline and each follow-up visit. FACT-F change scores were computed as the mean change in score (end of study score minus baseline score).Results:A total of 43 patients with mean age of 59 years were enrolled in the study. Results revealed a mean change in FACT-F subscale score of 5.0 (SE 1.06) for those who rated themselves as more tired, 1.28 (SE 1.00) for those who rated themselves as the same (no change), and −1.52 (SE 0.84) for those patients who rated themselves as less tired.Conclusions:We provide evidence on the magnitude of change in FACT-F score that is associated with the perception by patients of improvement in fatigue and magnitude of change in score that is associated with worsening in fatigue.

scholarly journals Fatigue after acquired brain injury impacts health-related quality of life: an exploratory cohort study

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Elisabeth Åkerlund ◽  
Katharina S. Sunnerhagen ◽  
Hanna C. Persson
Keyword(s):  
Quality Of Life ◽  
Brain Injury ◽  
Emotional State ◽  
Acquired Brain Injury ◽  
Executive Dysfunction ◽  
Health Related Quality ◽  
Related Quality ◽  
Health Related ◽  
Lower Hrqol

AbstractThis study aimed to identify the consequences of fatigue, fatigability, cognitive and executive functioning, and emotional state on health-related quality of life (HRQoL) in a clinical group of outpatients after acquired brain injury (ABI). This cross-sectional retrospective study included assessing outpatients at a rehabilitation clinic with WAIS-III working memory and coding subtests, and self-rating scales (Fatigue Impact Scale, Dysexecutive Questionnaire, Hospital Anxiety and Depression Scale, and the dimension of health-related quality of life from EQ-5D-3L). The predictive variables were investigated using a binary logistic regression with HRQoL as the dependent variable. Descriptive statistics and correlations were analyzed. Participants reported a lower than average HRQoL (95%), fatigue (90%), and executive dysfunction (75%). Fatigue had a significant impact and explained 20–33% of the variance in HRQoL with a moderate significance on depression (p = 0.579) and executive dysfunction (p = 0.555). Cognitive and executive function and emotional state showed no association with HRQoL. A lower HRQoL, as well as fatigue and cognitive and executive dysfunctions, are common after ABI, with fatigue is a partial explanation of a lower HRQoL.

scholarly journals MOVE UP STUDY RESULTS: WEIGHT LOSS POSITIVELY AFFECTS HEALTH-RELATED QUALITY OF LIFE BUT NOT DEPRESSIVE SYMPTOMS

2019 ◽  
Vol 3 (Supplement_1) ◽  
pp. S896-S896
Author(s):  
Elizabeth M Venditti ◽  
Robert M Boudreau ◽  
Anne B Newman ◽  
Michelle E Danielson ◽  
Lori A Kieffer ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Weight Loss ◽  
Depressive Symptoms ◽  
Physical Component Score ◽  
Health Related Quality ◽  
Sf 36 ◽  
Study Results ◽  
Related Quality ◽  
Health Related

Abstract Obesity is prevalent among older adults as are increases in depressive symptoms and declines in health-related quality of life (HRQOL). Healthy weight loss and mitigating mild depressive symptoms (MDS) and HRQOL could have critical public health significance. The Mobility and Vitality Lifestyle Program (MOVE UP) led by Community Health Workers delivered 32 healthy aging/weight management group sessions over 13 months. Data from 240 participants were evaluated to assess program impact on CES-D (20-item) depressive symptom and SF-36 HRQOL scores. Participants were 88% female, 28% black/other race, 42% ≥ college-educated. Mean (SD) age was 67.6 (4.1) and BMI was 34.7 (4.7). At baseline, average CES-D score was 7.9 (7.2) and 27.9 % (N = 67) had MDS, scoring 17.1 (6.2). Results show significant mean (SD) weight change of -12.7 (13.3) lb from baseline (p<0.0001). Overall, CES-D mean (SD) score change was -0.4 (6.7) (p=0.33); participants with MDS had an average CES-D decrease of -4.4 (7.8) points (p<0.0001). Further, HRQOL improved significantly in all realms, particularly the physical component score (p<0.0001). SF-36 (SD) total score improved +1.1 (7.6), mental + 2.1 (11.7), and physical + 5.0 (16.7). Regression analyses (age/sex adjusted) demonstrate that for each 5 lb of weight loss there was an average (SEM) 3.35 (1.49) point increase in SF-36 total score (p=0.03). The mitigation of depressive symptoms in the MDS subgroup was not significantly associated with weight loss but may reflect other positive effects of the intervention experience. Conversely, positive HRQOL changes appear to be driven strongly by weight loss.

scholarly journals Clinical features and health-related quality of life in adult patients with mucopolysaccharidosis IVA: the Spanish experience

2021 ◽  
Vol 16 (1) ◽  
Author(s):  
Pilar Quijada-Fraile ◽  
Elena Arranz Canales ◽  
Elena Martín-Hernández ◽  
María Juliana Ballesta-Martínez ◽  
Encarna Guillén-Navarro ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Clinical Manifestations ◽  
Self Care ◽  
Adult Patients ◽  
Health Related Quality ◽  
Cervical Surgery ◽  
Related Quality ◽  
Health Related ◽  
Mps Iva

Abstract Background Mucopolysaccharidosis (MPS) IVA or Morquio A syndrome is a progressive and disabling disease characterized by a deficiency of the enzyme N-acetylgalactosamine-6-sulphate sulphatase. Its clinical presentation is very heterogeneous and poorly understood in adults. The aim of this study was to describe the clinical manifestations of MPS IVA in adult patients in Spain and to assess their health-related quality of life (HRQoL). Results Thirty-three patients from nine reference centres participated in the study. The median age was 32 (interquartile range [IQR]: 20.5–40.5) years. The phenotype was classical in 54.5% of patients, intermediate in 33.3% of patients, and non-classical in 12.1% of patients. The most common clinical manifestation was bone dysplasia, with a median height of 118 (IQR: 106–136) cm. Other frequent clinical manifestations were hearing loss (75.7%), ligamentous laxity (72.7%), odontoid dysplasia (69.7%), limb deformities that required orthopaedic aids (mainly hip dysplasia and genu valgus) (63.6%), and corneal clouding (60.6%). In addition, 36.0% of patients had obstructive sleep apnoea/hypopnoea syndrome and 33.3% needed non-invasive ventilation. Cervical surgery and varisation osteotomy were the most common surgical interventions (36.4% each). Almost 80% of patients had mobility problems and 36.4% used a wheelchair at all times. Furthermore, 87.9% needed help with self-care, 33.3% were fully dependent, and 78.8% had some degree of pain. HRQoL according to the health assessment questionnaire was 1.43 (IQR: 1.03–2.00) in patients with the non-classical phenotype, but 2.5 (IQR: 1.68–3.00) in those with the classical phenotype. Seven patients were initiated on enzyme replacement therapy (ERT), but two of them were lost to follow-up. Lung function improved in four patients and slightly worsened in one patient. The distance achieved in the six-minute walk test increased in the four patients who could perform it. HRQoL was better in patients treated with elosulfase alfa, with a median (IQR) of 1.75 (1.25–2.34) versus 2.25 (1.62–3.00) in patients not treated with ERT. Conclusions The study provides real-world data on patients with MPS IVA. Limited mobility, difficulties with self-care, dependence, and pain were common, together with poor HRQoL. The severity and heterogeneity of clinical manifestations require the combined efforts of multidisciplinary teams.

scholarly journals Maternal emotional states in relation to their offspring weight status and health-related quality of life: Tehran Lipid and Glucose Study

2020 ◽  
Author(s):  
Parnian Parvin ◽  
Parisa Amiri ◽  
Sara Jalali-Farahani ◽  
Mehrdad Karimi ◽  
Mina MoeinEslam ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Weight Status ◽  
Emotional State ◽  
Emotional States ◽  
Z Score ◽  
Health Related Quality ◽  
Related Quality ◽  
Health Related ◽  
Z Scores

Abstract Background: Maternal characteristics have been known to be associated with parenting practices that could eventually influence their child’s weight and health-related quality of life (HRQoL). This study aimed to assess the direct and indirect associations of maternal emotional states (depression, anxiety and stress) with body mass index (BMI) and HRQoL in their children. Methods: This study was conducted within the framework of Tehran Lipid and Glucose Study (TLGS). Participants were children (n=231) who participated in the TLGS during 2014-2016 with complete data on maternal emotional states. Body weight and height of children were measured using standard protocol and BMI-Z scores were determined using Anthroplus. HRQoL in children and emotional states in mothers were assessed using the Iranian version of the pediatric quality of life inventory (PedsQL TM 4.0) and the depression, anxiety and stress scales (DASS-21) respectively. Structural equations modeling (SEM) was used to assess the direct and indirect relations of maternal emotional states with children’s BMI Z score and HRQoL. Results: Mean age, BMI Z-score and HRQoL total score in children were 13.8±3.1 years, 0.74±1.5 and 84.7±11.3 respectively. In mothers, median scores (Interquartile ranges) of DASS-21 in three scales including depression, anxiety and stress were 4(0-10), 6(2-12) and 14(8-20) respectively. Maternal level of education was significantly associated with DASS-21 scores (β=-0.23, 95% CI: -0.37,-0.07). Maternal DASS-21 scores were significantly associated with BMI Z scores only in girls (β=0.25, 95% CI: 0.06, 0.53). Significant determinants of HRQoL in boys were child’s age (β=-0.21, 95% CI: -0.40, -0.01), maternal education (β=-0.24, 95%CI: -0.44, -0.02) and emotional state (β=-0.24, 95% CI: -0.44, -0.03). Child’s age (β=-0.33, 95%-CI: -0.53, -0.10) and maternal emotional state (β=-0.31, 95% CI: -0.54, -0.08) were significantly associated with HRQoL in girls. Conclusion: Our results indicate maternal emotional states to be the important determinants of HRQoL in children, regardless of their weight status. Further research is recommended to examine the current hypothesized model in rural and sub-urban populations taking ino consideration more influential factors.

scholarly journals Gender Differences and Quality of Life in Parkinson’s Disease

2020 ◽  
Vol 18 (1) ◽  
pp. 198
Author(s):  
Pietro Crispino ◽  
Miriam Gino ◽  
Elena Barbagelata ◽  
Tiziana Ciarambino ◽  
Cecilia Politi ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Parkinson’S Disease ◽  
Gender Differences ◽  
Parkinson's Disease ◽  
Clinical Manifestations ◽  
Health Related Quality ◽  
Related Quality ◽  
Health Related ◽  
Non Motor Symptoms

Parkinson’s disease has been found to significantly affect health-related quality of life. The gender differences of the health-related quality of life of subjects with Parkinson’s disease have been observed in a number of studies. These differences have been reported in terms of the age at onset, clinical manifestations, and response to therapy. In general, women with Parkinson’s disease showed more positive disease outcomes with regard to emotion processing, non-motor symptoms, and cognitive functions, although women report more Parkinson’s disease-related clinical manifestations. Female gender predicted poor physical functioning and socioemotional health-related quality of life, while male gender predicted the cognitive domain of health-related quality of life. Some studies reported gender differences in the association between health-related quality of life and non-motor symptoms. Depression and fatigue were the main causes of poorer health-related quality of life in women, even in the early stages of Parkinson’s disease. The aim of this review was to collect the best available evidence on gender differences in the development of Parkinson’s disease symptoms and health-related quality of life.

scholarly journals Perception of health-related quality of life in children with chronic kidney disease by the patients and their caregivers: Multicentre national study results

2013 ◽  
Vol 22 (10) ◽  
pp. 2889-2897 ◽  
Author(s):  
Katarzyna Kiliś-Pstrusińska ◽  
Anna Medyńska ◽  
Irena Bałasz Chmielewska ◽  
Ryszard Grenda ◽  
Agnieszka Kluska-Jóźwiak ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Chronic Kidney Disease ◽  
Kidney Disease ◽  
National Study ◽  
Health Related Quality ◽  
Study Results ◽  
Related Quality ◽  
Health Related ◽  
Perception Of Health

scholarly journals Maternal Emotional States in Relation to Offspring Weight and Health-Related Quality of Life: Tehran Lipid and Glucose Study

2021 ◽  
Vol In Press (In Press) ◽  
Author(s):  
Parnian Parvin ◽  
Parisa Amiri ◽  
Sara Jalali-Farahani ◽  
Mehrdad Karimi ◽  
Mina Moein Eslam ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Emotional State ◽  
Structural Equations ◽  
The Body ◽  
Emotional States ◽  
Z Score ◽  
Health Related Quality ◽  
Related Quality ◽  
Health Related

Background: Maternal characteristics have been known to be associated with parenting practices, which could eventually influence their child’s weight and health-related quality of life (HRQoL). Objectives: This study aimed to assess the direct and indirect associations of maternal emotional states (depression, anxiety, and stress) with body mass index (BMI) and HRQoL in their children. Methods: This study was conducted within the framework of the Tehran lipid and glucose study (TLGS). Participants were the children (n = 231) enrolled in TLGS during 2014 - 2016, who had complete data on maternal emotional states. The body weight and height of children were measured using the standard protocol, and BMI Z-score was determined using Anthroplus. Also, HRQoL in children and emotional states in mothers were assessed using the Iranian version of the pediatric quality of life inventory (PedsQLTM4.0) and the depression, anxiety, and stress scale (DASS-21), respectively. Structural equations modeling (SEM) was used to assess the direct and indirect relations of maternal emotional states with children’s BMI Z-score and HRQoL. Results: Mean age, BMI Z-score, and HRQoL total score in children were 13.8 ± 3.1 years, 0.74 ± 1.5, and 84.7 ± 11.3, respectively. In the mothers, median DASS-21 scores (interquartile ranges) in the three scales of depression, anxiety, and stress were 4 (0 - 10), 6 (2 - 12), and 14 (8 - 20), respectively. Maternal level of education was significantly associated with the DASS-21 score (β = -0.23, 95% CI: -0.37,-0.07). Maternal DASS-21 score was significantly associated with BMI Z-score only in girls (β = 0.25, 95% CI: 0.06, 0.53). Significant determinants of HRQoL in boys were the child’s age (β = -0.21, 95% CI: -0.40, -0.01) and maternal education (β = -0.24, 95%CI: -0.44, -0.02) and emotional state (β = -0.24, 95% CI: -0.44, -0.03). The child’s age (β = -0.33, 95% CI: -0.53, -0.10) and maternal emotional state (β = -0.31, 95% CI: -0.54, -0.08) were significantly associated with HRQoL in girls. Conclusions: Our results indicated that the maternal emotional state was an important determinant of HRQoL in children, regardless of their weight status. Further research is recommended to examine the current hypothesized model in rural and suburban populations, taking into consideration more influential factors.

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