scholarly journals Features of erosive­ulcerative lesions of stomach and duodenum in patients with migraine

2018 ◽  
Vol 96 (9) ◽  
pp. 826-832
Author(s):  
A. I. Dolgushina ◽  
M. I. Karpov ◽  
Olga V. Serousova ◽  
V. V. Osipova ◽  
A. F. Vasilenko ◽  
...  

A number of epidemiological studies have shown the Association of migraine with peptic ulcer disease (JB), however, the processes underlying the pathogenesis and features of the course of these diseases have not been fully studied. Material and methods. A comprehensive examination of the gastrointestinal tract was performed in 114 patients with migraine. Focused on the major clinical and psychological characteristics of patients depending on the availability of gastroduodenopathies, especially pain therapy and serotonin levels in the blood serum. Results. In 18.4% of patients with migraine, regardless of its type, erosive and ulcerative lesions of the stomach and duodenum were detected. In patients with chronic migraine, gastric ULCER developed more often (PF =0.022), the clinical features of the combination of migraine and ULCER were more pronounced intensity of abdominal pain and heartburn. High (5 or more times a week) frequency of nonsteroidal anti-inflammatory drugs (NSAIDs) was an important ulcerogenic factor in patients with migraine. Serotoninergic hypofunction can be discussed as a mechanism that determines the comorbid relationship of migraine and JB. The combination of migraine with NSA contributed to the formation of a more severe course of migraine. In assessing the quality of life indicators of all scales in such patients were lower . Gastropathy can be considered as an additional factor of migraine chronization, requiring appropriate therapeutic interventions to improve the quality of life of patients.

Author(s):  
Sadagat Ganbarovna Guseinova ◽  
S. S Imamverdieva ◽  
E. E Mustafaeva ◽  
M. Yu Mamedova ◽  
K. N Yusifova

Clinical-neurophysiological bases of the combined use of Nucleo CMF forte preparation and interference therapy in the complex treatment of patients with vertebrogenic radiculopathies were studied. The beneficial effect of this therapeutic complex on the clinical course of the disease, more pronounced analgesic effect and regression of clinical manifestations, as well as improvement of quality of life indicators were proved. It has been established that the therapeutic effect of the complex application of Nucleo CMF forte and interference therapy lies in the improvement in the afferent and efferent links of the neuromotor apparatus, as well as the functional state of the spinal alpha-motoneurons associated with the acceleration of the regenerative processes. Activation of regenerative processes can also be associated with the restoration of certain morphological elements of the nervous system under the action of Nucleo CMF forte, as well as the normalization of the synthesis of complex lipids involved in cellular metabolism and synthesis of substances for the structural restoration of peripheral nerves. Carrying out neurotropic pharmacotherapy in combination with physiotherapy helps optimize therapeutic tactics in patients with vertebrogenic radiculopathies and is aimed at improving the quality of treatment, reducing the using of number of non-steroidal anti-inflammatory drugs and the frequency of relapse of the disease, and improving the quality of life of patients.


2020 ◽  
Vol 29 (4) ◽  
pp. 2097-2108
Author(s):  
Robyn L. Croft ◽  
Courtney T. Byrd

Purpose The purpose of this study was to identify levels of self-compassion in adults who do and do not stutter and to determine whether self-compassion predicts the impact of stuttering on quality of life in adults who stutter. Method Participants included 140 adults who do and do not stutter matched for age and gender. All participants completed the Self-Compassion Scale. Adults who stutter also completed the Overall Assessment of the Speaker's Experience of Stuttering. Data were analyzed for self-compassion differences between and within adults who do and do not stutter and to predict self-compassion on quality of life in adults who stutter. Results Adults who do and do not stutter exhibited no significant differences in total self-compassion, regardless of participant gender. A simple linear regression of the total self-compassion score and total Overall Assessment of the Speaker's Experience of Stuttering score showed a significant, negative linear relationship of self-compassion predicting the impact of stuttering on quality of life. Conclusions Data suggest that higher levels of self-kindness, mindfulness, and social connectedness (i.e., self-compassion) are related to reduced negative reactions to stuttering, an increased participation in daily communication situations, and an improved overall quality of life. Future research should replicate current findings and identify moderators of the self-compassion–quality of life relationship.


2001 ◽  
Vol 120 (5) ◽  
pp. A491-A491
Author(s):  
G GONZALEZSTAWINSKI ◽  
J ROVAK ◽  
H SEIGLER ◽  
J GRANT ◽  
T PAPPAS

2020 ◽  
Vol 17 (6) ◽  
pp. 76-91
Author(s):  
E. D. Solozhentsev

The scientific problem of economics “Managing the quality of human life” is formulated on the basis of artificial intelligence, algebra of logic and logical-probabilistic calculus. Managing the quality of human life is represented by managing the processes of his treatment, training and decision making. Events in these processes and the corresponding logical variables relate to the behavior of a person, other persons and infrastructure. The processes of the quality of human life are modeled, analyzed and managed with the participation of the person himself. Scenarios and structural, logical and probabilistic models of managing the quality of human life are given. Special software for quality management is described. The relationship of human quality of life and the digital economy is examined. We consider the role of public opinion in the management of the “bottom” based on the synthesis of many studies on the management of the economics and the state. The bottom management is also feedback from the top management.


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