scholarly journals Insuffisance Rénale Aigue Obstétricale : Expérience De La Maternité Issaka GAZOBY De Niamey (Niger)

2016 ◽  
Vol 12 (33) ◽  
pp. 281
Author(s):  
Zeinabou Maiga Moussa Tondi ◽  
Madi Nayama ◽  
Yaya Kane ◽  
Moumouni Garba ◽  
Ahmet Tall Lemrabott ◽  
...  

Introduction Acute renal failure (ARF) is a serious obstetric complication of pregnancy, a real health problem in developing countries. It is more related to the pathologies of pregnancy affecting the mother rather than the fetus. The purpose of our study was to assess sociodemographic, clinical, therapeutic and evolutionary features in obstetric acute renal failure. Materials and Methods: A cross sectional study of 6 months (August 2015- January 2016) was conducted. The study involved pregnant women over 20- week amenorrhea including the immediate postpartum admitted for acute renal failure. Results: Thirty-two patients were involved. The mean age was 25.21 ± 5.14 years. Most of them were first-time mothers (53.1%). Surrounding hospital exits account for 71.9% of the admissions. 31.25% (N = 10) of the patients did not receive any antenatal care. The main clinical signs at admission were hypertension (86.6%), oliguria (40.5%) and edema syndrome (37.5%). Eclampsia and severe pre-eclampsia represented the causes of the ARF in 68.75% cases. Considering 8 patients (25%) who were supposed to undergo dialysis therapy, only one took the treatment. The average hospital stay was 15.20 ± 7.45 days. Renal function resolved in 68.75% of patients and 15.62% developed chronic renal sequelae. At the end of the study, we recorded 5 cases of maternal deaths and 10 cases of fetal death in utero. Conclusion: Obstetric ARF remains a serious complication of pregnancy for mother and child. It should be noted that hemodialysis was not accessible to all patients who were entitled to it due to lack of financial means. Therefore, regular monitoring of pregnancies should be prioritized, and, if possible, ensure that hemodialysis sessions are funded.

2021 ◽  
Vol 28 (05) ◽  
pp. 640-646
Author(s):  
Shaheena Zafar ◽  
Riffat Jaleeel ◽  
Kouser Karim Lodhani

Objective: To determine the frequency of factors leading to acute renal failure in obstetric patients. Study Design: Cross Sectional study. Setting: Department of Obstetrics and Gynecology, Civil Hospital Karachi, Tertiary Care Hospital. Period: July 2015- Jan 2016. Material & Methods: Total 250 women during pregnancy and within 42 days after delivery who were diagnosed as ARF were included. Serum creatinine was done on admission and then after 24 hours of delievery. Those with urine output < 30ml / hour and serum creatinine > 1.5 mg / dl were recruited. All data was recorded on proforma. Results: The average age of the women was 29.36±5.87 years. Post-partum hemorrhage was the important and common factor i.e. 40.4%, followed by placental abruption 25.6%, Severe pre-eclampsia 18.4%, puerperal sepsis 8.4% and eclampsia 7.2%. Conclusion: Ante partum hemorrhage like placental abruption, eclampsia and preeclampsia, and postpartum hemorrhages’ are the major causes of obstetrical ARF. Good antenatal care and provision of universal health facility can prevent this dangerous condition. Though it is a treatable and curable complication, but if not diagnosed and treated timely, it can lead to significant maternal morbidity and mortality.


2020 ◽  
Vol 27 (06) ◽  
pp. 1285-1290
Author(s):  
Ahmed Ali Kanhar ◽  
Waseem Raja Memon ◽  
Nasrullah Aamer ◽  
Bahkat Ali Sial ◽  
Abdul Aziz Sahito ◽  
...  

Objective: To determine the frequency of acute renal failure in patients presented with Blackstone poisoning in a tertiary care Hospital. Study Design: Cross sectional study. Setting: Medical wards and ICU at Peoples Medical College Hospital, Nawabshah. Period: September 2017 to March 2018. Material & Methods: All the patients of age 20 to 50 years having Paraphenylenediamine (PPD) poisoning (kala-patthar) during ≥6 hours after ingestion and either of gender were included. AKI was labelled as positive if either of any stage was present on the basses of urine output measurement for 24 hours through urine beg r urine output (UO) criteria. All the data was documented in self-made proforma. Results: The mean age for patients was 24.9±8.9 years, 46(19.08%) subjects were male and 195(80.91%) were female. 18(7.5%) study subjects had acute renal failure, out of them 6 study subjects had ARF of stage I, 5 patients had stage II and 7 study subjects had acute renal failure stage III. Conclusion: Acute renal injury is a common complication following PPD ingestion 7.5%. Paraphenylenediamine toxicity is a threat to the region of Asia and is evolving as a substitute to the poisoning of organophosphorus due to its easy accessibility and low cost.


2016 ◽  
Vol 53 (4) ◽  
pp. 551-558 ◽  
Author(s):  
David Cucchiari ◽  
Manuel Alfredo Podestà ◽  
Elisa Merizzoli ◽  
Albania Calvetta ◽  
Emanuela Morenghi ◽  
...  

2020 ◽  
Vol 27 (10) ◽  
pp. 2149-2153
Author(s):  
Muhammad Shoaib Akhtar ◽  
Aziz Ur Rehman ◽  
Kiran Akbar ◽  
Mazhar Hussain ◽  
Moazzam Ali Atif ◽  
...  

Organophosphate (OP) compounds are insecticides whose toxicity is well reported. They can virtually involve any organ and cardiac and renal complications are one of the most dreadful ones. Objectives: To determine the frequencies of acute renal failure and cardiac complication in patients with Organophosphorus poisoning. Study Design: Cross Sectional study. Setting: Department of Medicine, Sheikh Zayed hospital, Rahim Yar khan. Period: January 2015 to December 2015. Material & Methods: All adult cases with documented history of Organophosphorus poising either trans-dermally or oral ingestion with either accidental or intentional intake were included. The cases then underwent ECG and renal function tests. The abnormalities in ECG were documented and the urea more than 30 mg/dl and creatinine more than 1.5 mg/dl was labeled as acute renal failure. Results: In this study there were 100 cases, 58 (58%) were females and 42 (42%) males. The mean age was 22.58±48 years and mean duration of OP taken was 7±0.24 hours. Complications were seen in 35 (35%) cases out of which 6 had ARF and 29 had cardiac arrhythmias. IA, 6 had prolonged QT and remaining 3 observed ventricular tachycardia (VT). ARF was common in females but there was no significant association with any study variables. However a near significant was seen in cases that presented with more than 4 hours of toxicity (p= 0.07). Cardiac arrhythmias were also more common in females. There was significant association of it with oral intake and with suicidal intention with p= 0.001 and 0.001. Conclusion: OP poisoning is common and cardiac complications are more than acute renal failure. Oral intake and with suicidal intention are significantly associated with cardiac complications.


2020 ◽  
Vol 3 (1) ◽  
pp. 19-22
Author(s):  
Deddy C. Kalonji ◽  
◽  
Lebrun N. Kembo ◽  
Matthieu Ngombe ◽  
Olivier Mukuku ◽  
...  

Purpose Acute renal failure (ARF) or acute kidney injury (AKI) is one of the major criteria for the severity of malaria according to WHO. The objective was to determine the frequency as well as to evaluate the management and follow-up of ARF during malaria in children in Lubumbashi. Material and methods This is a descriptive cross-sectional study over 48 months (January 1st, 2016 to December 30th, 2019) carried out at the pediatric service of the University Clinics of Lubumbashi. All children with an ARF with a positive thick blood smear were included in the study. Data were analyzed with SPSS 19 software. Results During this period, 910 patients (49.1%) were admitted for malaria. Among them, 14 patients, i.e. an intra-hospital prevalence of 0.78%, of which 6 boys (42.9%) and 8 girls (57.1%) had ARF. The mean age is 7.9±3.5 years. The serum creatinine level was between 0.54 and 15.2 mg/dL with a mean of 5.7 mg/dL. Kidney dialysis was only effective in 3 patients (21.4%) and diuretics were given 100% in all children. The mean length of stay was 13.4±8.7 days (range: 1 day and 18 days). Mortality was 21.4%. Conclusion The present study shows that ARF in childhood malaria in Lubumbashi is infrequent but of high mortality in our environment with limited resources where care is lacking and monitoring difficult.


mBio ◽  
2014 ◽  
Vol 5 (5) ◽  
Author(s):  
Mina C. Hosseinipour ◽  
Kristen M. Sweet ◽  
Jie Xiong ◽  
Dan Namarika ◽  
Albert Mwafongo ◽  
...  

ABSTRACTKaposi’s sarcoma (KS), caused by KS-associated herpesvirus (KSHV), is the most common cancer among HIV-infected patients in Malawi and in the United States today. In Malawi, KSHV is endemic. We conducted a cross-sectional study of patients with HIV infection and KS with no history of chemo- or antiretroviral therapy (ART). Seventy patients were enrolled. Eighty-one percent had T1 (advanced) KS. Median CD4 and HIV RNA levels were 181 cells/mm3and 138,641 copies/ml, respectively. We had complete information and suitable plasma and biopsy samples for 66 patients. For 59/66 (89%) patients, a detectable KSHV load was found in plasma (median, 2,291 copies/ml; interquartile range [IQR], 741 to 5,623). We utilized a novel KSHV real-time quantitative PCR (qPCR) array with multiple primers per open reading frame to examine KSHV transcription. Seventeen samples exhibited only minimal levels of KSHV mRNAs, presumably due to the limited number of infected cells. For all other biopsy samples, the viral latency locus (LANA, vCyc, vFLIP, kaposin, and microRNAs [miRNAs]) was transcribed abundantly, as was K15 mRNA. We could identify two subtypes of treatment-naive KS: lesions that transcribed viral RNAs across the length of the viral genome and lesions that displayed only limited transcription restricted to the latency locus. This finding demonstrates for the first time the existence of multiple subtypes of KS lesions in HIV- and KS-treatment naive patients.IMPORTANCEKS is the leading cancer in people infected with HIV worldwide and is causally linked to KSHV infection. Using viral transcription profiling, we have demonstrated the existence of multiple subtypes of KS lesions for the first time in HIV- and KS-treatment-naive patients. A substantial number of lesions transcribe mRNAs which encode the viral kinases and hence could be targeted by the antiviral drugs ganciclovir or AZT in addition to chemotherapy.


1970 ◽  
Vol 39 (1) ◽  
pp. 24-27
Author(s):  
Sabrina Q Rashid

This study was conducted to determine fetal biparietal diameter and abdominal circumference ratio in Bangladesh. There is still no table of this ratio in our country. A prospective, cross-sectional study was conducted on well dated, singleton fetuses of healthy pregnant women. One table and two graphs were prepared by fitting Polynomial regression model. Percentiles, mean and two standard deviations were derived of the ratio. Fetal charts of the raw data with superimposed fitted curves were constructed. The model showed a good fit to the data of 1223 subjects. It covered 95% of the population and gave 3rd, 10th, 50th, 90th and 97th percentiles. This chart can be useful for accurate assessment of fetal biparietal diameter and abdominal circumference ratio to determine the type of fetal growth abnormality, symmetrical or asymmetrical. This is the first time that this ratio has been studied in Bangladesh. Key words: Biparietal diameter; abdominal circumference. DOI: 10.3329/bmj.v39i1.6229 Bangladesh Medical Journal 2010; 39(1): 24-27


2006 ◽  
Vol 124 (1) ◽  
pp. 42-44 ◽  
Author(s):  
Fabio Luiz de Menezes Montenegro ◽  
Marcos Roberto Tavares ◽  
Marcelo Doria Durazzo ◽  
Claudio Roberto Cernea ◽  
Anói Castro Cordeiro ◽  
...  

CONTEXT AND OBJECTIVE: Adequate management of parathyroid carcinoma apparently relates to the surgeon’s ability to identify it at the first operation. The objective of this paper was to evaluate the role of clinical suspicion in the management of parathyroid carcinoma. DESIGN AND SETTING: Retrospective analysis of parathyroid carcinoma patients treated in Department of Head and Neck Surgery, Faculdade de Medicina da Universidade de São Paulo. METHODS: Cross-sectional study of 143 patients who underwent surgery from 1995 to 2000, due to hyperparathyroidism. These cases were reviewed to ascertain whether preoperative and intraoperative suspicion of parathyroid carcinoma were helpful during the operation, and which factors demonstrated the suspicion of cancer best. RESULTS: Among 66 patients with primary hyperparathyroidism there were four cases of parathyroid carcinoma (6.1%), and one case was found in secondary hyperparathyroidism (1.3%). Palpable nodules were found in five patients with primary hyperparathyroidism, four of them with parathyroid carcinoma. Preoperative levels of calcium in primary hyperparathyroidism with cancer patients varied from 12.0 mg/dl to 18.2 mg/dl. Two patients had gross macroscopic spread of the tumor to adjacent structures. Except for one patient, with extensive disease, tumors were resected en bloc. In secondary hyperparathyroidism, parathyroid carcinoma was found in a fifth mediastinal gland. One atypical adenoma was observed. CONCLUSIONS: High levels of calcium, palpable tumors and adherence to close structures are more common in parathyroid carcinoma. These clinical signs may be helpful for decision-making during parathyroid surgery.


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