scholarly journals Effect Of Trabeculectomy On Ocular Biometry And Refractive Errors In Pediatric Glaucoma

2021 ◽  
Vol 17 (29) ◽  
pp. 291
Author(s):  
Nouhoum Guirou ◽  
Youssouf Dembélé ◽  
Abdoulaye Napo ◽  
Théra Japhet ◽  
Drissa Moriba Coulibaly ◽  
...  

Background: Pediatric glaucoma triggers refractive errors by modifying the biometry of the eye. This study was conducted with the objective of estimating the short-term biometric and refractive changes prior to and post trabeculectomy in pediatric glaucoma. Material and Methods: A 12-month, descriptive, cross-sectional study was carried out from January to December 2019, using patients operated on for pediatric glaucoma. Pre- and post-operative biometric and refraction measurements were noted. Visual acuity, axial length, corneal diameter and refraction were obtained. All ethical requirements (anonymity, free, informed, and continuous consent) were satisfied. Data analysis was done using SPSS 20.0. Results: In the present study, 47 eyes of 27 patients were surgically operated upon, from January 2019 to December 2019 at CHU-IOTA. The predominant sex was male (17 patients) at 63%, giving a sex ratio (M / F) of 1.7. The mean age was 5.04 ± 4.24. Preoperatively, the mean corneal diameter, and D90 were respectively 13.83 ± 1.51 and 12.55 ± 0.99. Preoperatively, the mean axial length, and D90, were 23.87 ± 1.29 and 22.28 ± 1.07, respectively. Preoperatively and at three month, the mean myopia (n = 36), were respectively -3.13 ± 1.83 and -1.59 ± 0.97. The mean preoperative astigmatism (n = 47) and D90 were respectively, -1.59 ± 0.77 and -1.23 ± 0.57. A statistically significant relationship (p <0.05) was found to exist between the preoperative and postoperative data of the axial length, corneal diameter, and refractive errors. Conclusions: Trabeculectomy significantly exerts a short-term positive impact on the biometrics and refraction by modifying the initial measurements and diopters. 

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Lu Huo ◽  
Yuanyuan Qi ◽  
Shaozhen Zhao

Abstract Background Infancy is the of a child’s visual development. Refractive errors, especially myopia, are a common vision disorder. Thus, the purpose of this study was to explore refractive errors and risk factors for myopia among infants aged 1–18 months in Tianjin, China. Methods A total of 583 infants aged 1–18 months participated in this cross-sectional study at Tianjin Women’s and Children’s Health Center in China from February 2019 to November 2020. Each infant received a complete ophthalmologic examination, and myopia-related risk factors were investigated using a questionnaire. Results A total of 583 eligible infants participated in this study, including 312 (53.5%) boys and 271 (46.5%) girls. There were 164 (28.1%) premature born infants. The mean age was 6.59 ± 4.84 months (range, 1–18 months). The mean spherical equivalent (MSE) for the right eye was 1.81 D ± 1.56 D, with no difference related to sex (P = 0.104). Refractive state showed an average hyperopia of +2.74 ± 1.74 D at early ages, followed by a trend toward less hyperopia, finally reaching +1.35 ± 1.44 D at the age of 18 months (P ≤0.001). The overall prevalence rates of myopia (MSE ≤ −0.50 D), emmetropia (−0.50 D<MSE<+0.50 D), hyperopia (MSE ≥ +2.00 D), and astigmatism (≥ 1.50 D) were 5.1%, 10.8%, 42.7%, and 49.9%, respectively. The chi-square tests showed that gender, gestational age ≥37 weeks, winter birth, prenatal exposure to environmental tobacco smoke, and parental history of high myopia were associated with children’s myopia (P = 0.022, P = 0.023, P = 0.038, P = 0.015, P<0.001, respectively). Conclusions Among Chinese infants in Tianjin, hyperopia and astigmatism were the most frequent refractive errors, and the diopter was lower in individuals with higher age. In a small number of infants with myopia, genetic factors and the prenatal environment were associated with the early onset of myopia.


2020 ◽  
Author(s):  
Amr A. Gab-Alla

Abstract Background: To generate reference values of the central corneal thickness (CCT) with different refractive errors for the adult Egyptian population. Methods: A retrospective, observational, and cross-sectional study of 2200 eyes in 1166 subjects scheduled for LASIK, who came to private refractive eye center, Ismailia, Egypt. The study period was from January 2018 to January 2020. The subjects were divided into a broad range of myopia with spherical equivalent (SE) <-0.5D and hyperopia SE> +0.5D. Then, the myopic eyes divided into low (SE>-3.0D), moderate (SE-3.0D to >-6.0D), and high (SE<-6.0D). Similarly, the hyperopic eyes were divided into low (SE<+3.0 D) and moderate (SE+3.0D to <+6.0D) and high >+6.0D. The refractive error was measured by an auto-refractometer (Topcon, Tokyo Optical Co., Ltd., Japan), and CCT was measured using Sirius (CSO, Florence, Italy). Results: The data of 1100 myopic eyes in 556 subjects (30.5% males and 69.5% females) and 1100 hyperopic eyes in 610 subjects (33.6% males and 66.4% females). The mean+SD of CCT for the total myopic subjects was 531.98+32.92μm, range (406 to 636μm). The mean+SD of SE was -4.1±2.5D, range (-0.5 to -12.0D). The mean+SD of CCT for the total hyperopic subjects was 529±38.8μm, range (448 to 619 μm). The mean+SD of SE was +3.65+1.97D, range (+0.5 to +8.5D).Conclusion: In this study, the mean of CCT of the Egyptian population was 531.9 μm for myopic and 529μm for hyperopic subjects respectively. The myopic and hyperopic subjects show a reduction in CCT with age. Females have a thinner cornea than males, 23.6% of the myopic eyes, and 16.5% of the hyperopic eyes have CCT less than 500μm.


2018 ◽  
Vol 2018 ◽  
pp. 1-10 ◽  
Author(s):  
Luoli Zhang ◽  
Xiangui He ◽  
Xiaomei Qu ◽  
Xiaofang You ◽  
Bingjie Wang ◽  
...  

Purpose. To investigate the refraction and ocular biometry characteristics and to examine the prevalence of refractive errors in preschool children aged 3 to 6 years in Shanghai, China. Methods. A school-based cross-sectional study was conducted in Jiading and Xuhui District, Shanghai, in 2013. We randomly selected 7 kindergartens in Jiading District and 10 kindergartens in Xuhui District, with a probability proportionate to size. The children underwent comprehensive eye examinations, including cycloplegic refraction and biometric measurements. Myopia, hyperopia, astigmatism were defined as spherical equivalent (SE) ≤ −0.50 D, SE ≥ +2.00 D, and cylindrical diopters ≤ −1.00 D. Results. The mean SE for 3- to 6-year-old children was +1.20 D (standard deviation [SD] 1.05), and the mean axial length (AL) was 22.29 mm (SD 0.73). The overall prevalence of myopia and astigmatism was 3.7% and 18.3%, respectively. No difference in prevalence of astigmatism was found across age groups. There was a statistically significant association between lower cylindrical diopters and higher spherical diopters (Spearman’s correlation: −0.21, P<0.001). Conclusion. Chinese children aged 3 to 6 years in the Shanghai area were mostly mildly hyperopic, with a low prevalence of myopia. Refractive astigmatism for children may be relatively stable throughout the preschool stage. Astigmatism was significantly associated with refractive error.


Author(s):  
Tadesse Melaku ◽  
Akshaya Srikanth Bhagavathula ◽  
Yonas Getaye ◽  
Sewunet Admasu ◽  
Ramadan Alkalmi

This study aimed to compare the perceptions of pharmacy clerkship students and clinical preceptors of preceptors’ teaching behaviors at Gondar University. A cross-sectional study was conducted among pharmacy clerkship students and preceptors during June 2014 and December 2015. A 52-item structured questionnaire was self-administered to 126 students and 23 preceptors. The responses are presented using descriptive statistics. The Mann-Whitney U test was applied to test the significance of differences between students and preceptors. The response rate was 89.4% for students and 95.6% for preceptors. Statistically significant differences were observed in the responses regarding two of the five communication skills that were examined, six of the 26 clinical skills, and five of the 21 parameters involving feedback. The mean scores of preceptors (2.6/3) and students (1.9/3) regarding instructors’ ability to answer questions were found to be significantly different (P= 0.01). Students and preceptors gave mean scores of 1.9 and 2.8, respectively, to a question regarding preceptors’ application of appropriate up-to-date knowledge to individual patients (P= 0.00). Significant differences were also noted between students and instructors regarding the degree to which preceptors encouraged students to evaluate their own performance (P= 0.01). Discrepancies were noted between students and preceptors regarding preceptors’ teaching behaviors. Preceptors rated their teaching behaviors more highly than students did. Short-term training is warranted for preceptors to improve some aspects of their teaching skills.


2021 ◽  
Vol 14 (2) ◽  
pp. 292-298
Author(s):  
Masoud Khorrami-Nejad ◽  
◽  
Alireza Akbarzadeh Baghban ◽  
Bahram Khosravi ◽  
◽  
...  

AIM: To evaluate the effect of axial length (AL) and anterior chamber depth (ACD) on peripheral refractive profile in myopic patients compared to emmetropic participants. METHODS: This cross-sectional study was conducted in right eyes of 58 participants of whom 38 were emmetropic and 20 were myopic. Central and peripheral refraction were measured at 10°, 20°, and 30° eccentricities in nasal and temporal fields using an open-field autorefractor. The Lenstar LS900 was used to measure ACD and AL. The participants were divided into three groups of short (<22.5 mm), normal (22.5-24.5 mm), and long eye (>24.5 mm) according to AL and three groups of low ACD (<3.00 mm), normal ACD (3.00-3.60 mm), and high ACD (>3.60 mm) according to ACD. RESULTS: The mean age of the participants was 22.26±3.09y (range 18-30y). The peripheral mean spherical refractive error showed a hypermetropic shift in myopic and emmetropic groups although this shift was more pronounced in the myopic group. The results showed significant changes in the spherical equivalent, J0, and J45 astigmatism in all gazes with an increase in eccentricity (P<0.001). The pattern of refractive error changes was more noticeable in long and short eyes versus normal AL eyes. Moreover, the pattern of peripheral refractive changes was much more prominent in the high ACD group versus the normal ACD group and in the normal ACD group versus the low ACD group. CONCLUSION: Peripheral refraction changes are greater in participants with AL values outside the normal range and deeper ACD values compared to participants with normal AL and ACD.


2018 ◽  
Vol 103 (8) ◽  
pp. 1173-1178 ◽  
Author(s):  
Ahmad M Mansour ◽  
Michael W Stewart ◽  
Salma W Yassine ◽  
Carl-Joe Z Mehanna ◽  
Antonio Marcelo B Casella ◽  
...  

AimTo study the macular structure and vasculature in consecutive nanophthalmic eyes using optical coherence tomography angiography.MethodsThis is a prospective, multicentre, cross-sectional study of patients with nanophthalmos (one or both eyes). The superficial and deep foveal avascular zones (FAZ) were measured both manually and with the machine’s built-in automated measurement tool. Correlations between best corrected visual acuity (BCVA), central macular thickness (CMT) and subfoveolar choroidal thickness (SFCT) were calculated.ResultsSixty-five eyes of 35 subjects (16 men and 19 women) with a mean age of 37.4 years were analysed. The mean±SD of refractive error was 14.3±3.2 dioptres, axial length was 16.4±1.6 mm, CMT was 410.2±128.3 µm and SFCT was 450.1±108.3 µm. FAZ was unmeasurable small size in both the superficial and deep capillary plexus in all eyes, along with tortuosity of the superficial foveal capillaries and large vessels. Foveal folds were present in 29 eyes. Disc drusen was detected in 27 eyes and was absent in 31 eyes, while fundus autofluorescence was positive in 17 and negative in 24 eyes. BCVA varied from 20/20 to 20/800, with a mean of 20/76. Using Spearman’s correlation, logarithm of the minimum angle of resolution BCVA correlated negatively with axial length (r=−0.30; p=0.015).ConclusionsFAZ attenuation, capillary tortuosity, foveal folds and thickened subfoveal choroid characterise the nanophthalmic macula. These findings may result from a redundant retina and the absence of apoptotic foveolar retraction because of developmental arrest of the optic vesicle after closure of the embryonic fissure.


2020 ◽  
Author(s):  
Julia Gutierrez-Vazquez ◽  
Lorenzo Ismael Perez-Sanchez ◽  
Maria Satrustegui-Lapetra ◽  
Juan Jose Arevalo-Manso ◽  
Juan Jesus Gomez-Herrera ◽  
...  

Aims: To determine the reliability of transpalpebral ultrasound in B-mode (B-TUS) with a high-resolution linear probe (18 MHz) in estimating both the ocular anterior chamber depth (ACD) and axial length (AL), as well as its agreement with the IOL Master 500 optical biometer. Material and methods: Cross-sectional study on 82 eyes of 41 volunteers with no history of eye disease. ACD and AL were determined using B-TUS and the IOL Master 500. The agreement between the two tech-niques and the variability of B-TUS (inter- and intra-observer) were analyzed with the Bland-Altman method. To this end, the mean difference between measures±1.96 SD was calculated to determine the limits of agreement (LoA). Results: The mean difference±1.96SD between B-TUS and the IOL Master 500 was -0.41±0.25mm for ACD (p<0.001) and -0.48±0.45 mm for AL (p<0.001). The maximum variability for B-TUS (average±1.96SD) was 0.00±0.35 mm at the inter-observer level for AL, and 0.00±0.18mm at the intra-observer level for AL. Conclusion: The determination of ACD and AL by B-TUS has a good re-liability and variability, in line with other sonographic techniques. However, it systematically provides smaller measurements than those obtained with the IOL Master 500, similar to the conventional ultrasound techniques. B-TUS could be useful in the assessment and follow-up of a wide range of ophthalmic diseases, in which a high accuracy in ACD and AL is not determinant.


2021 ◽  
Vol 8 (11) ◽  
pp. 1657
Author(s):  
Anthony O. Betiku ◽  
Adeola O. Onakoya ◽  
Olufisayo T. Aribaba ◽  
Omodele O. Jagun

Background: Aim of the study was to determine the relationship between axial length (AL), keratometry and central corneal thickness (CCT), and refractive errors in adult patients attending the Guinness eye centre (GEC), Lagos university teaching hospital (LUTH) Idi-Araba, Lagos.Methods: A descriptive cross-sectional study conducted among consecutive patients aged 16 years and above with refractive errors attending the GEC, LUTH. Ocular parameters measured included AL, anterior corneal curvature, CCT and refractive errors. AL and keratometry were measured with IOL master and CCT with ultrasonic A scan pachymeter. Refraction was done with auto-refractor-keratometer. Data analysis was done with statistical package for social science (SPSS) 20. Results: A total of 394 patients were studied, 157 males and 237 females. The age range was 16-65 years, mean -37.9±13.3 years and median -36.5 years. There were more myopic patients 215 (54.6%) than hyper-metropes 179 (45.4%). The mean AL was 23.9±1.1 mm and eyes with longer AL were more likely to be myopic (r=-0.676, p<0.001); to have flatter cornea (r=0.519, p<0.001) and thicker cornea (r=0.149, p=0.003). The mean CCT was 520.3±31.0 µm. There was a weak negative correlation between CCT and refractive error (r=-0.111, p=0.027).Conclusions: The mean CCT was lower than the mean CCT of other Nigerian studies. Hypermetropic patients were more likely to have thinner corneas. This may lead to underestimation of intraocular pressure (IOP) in these patients. Significant correlation was seen between AL and refractive error, CCT and keratometry. AL correlated with less spherical equivalent refractive error, flatter and thicker cornea. It is therefore important to measure the CCT of all patients going for refractive surgery to detect those at risk of developing corneal ectasia following refractive surgery.


2021 ◽  
Vol 14 (1) ◽  
Author(s):  
Ari Shinojima ◽  
Toshihide Kurihara ◽  
Kiwako Mori ◽  
Yujiro Iwai ◽  
Akiko Hanyuda ◽  
...  

Abstract Objective The purpose of this study is to analyze axial length, body height, hand length, and foot length to find new factors that predict myopia and to identify gender differences as one of the factors of high myopia. A cross-sectional study was conducted as a single observation. Body height, hand length, and foot length were measured according to standard anthropometric methods. Axial length, retinal thickness, and choroidal thickness were measured using the IOL Master 700 and the Heidelberg Spectralis-OCT. To account for body height differences among participants, foot length/body height and hand length/body height were analyzed using a mixed-effects model. Results A total of 80 eyes (men, n = 20, 40 eyes; women, n = 20, 40 eyes) were analyzed. The mean age was 33.5 years (range 21–59 years, SD: 9.6). For choroidal thickness, there was a significant association with axial length in men (p < 0.001) and a trend toward an association in women (p = 0.072). There was also a significant association between foot length/body height and axial length in men (p = 0.015), but not in women (p = 0.58). These results suggest that factors that determine body height and foot length may be related to axial length, although they vary by gender.


2019 ◽  
Author(s):  
Minjie Chen ◽  
Jinhui Dai ◽  
Xinghuai Sun

Abstract Background: There is an compensatory effect between corneal astigmatism (CA) and internal astigmatism (IA). And the refractive astigmatism (RA) decreased fast in the early 3 years. Nevertheless, little attention was paid to the change in astigmatism in preschool children. Thus, we aimed to investigate the age-dependent distribution of astigmatism and its component in Chinese preschool children from year 3 to year 6 and also, to study the relationship between ocular biometry and IA. Methods: Automated refraction, keratometry and axial length (AL) were performed in this cross-sectional study. The IA was determined as the vector difference between RA and CA. The magnitude and type (with-the-rule WTR, against-the-rule ATR, oblique) of RA, CA and IA were investigated according to the age. Spearman correlation was adopted to detect the factors that may influence IA. Results: A total of 2315 subjects (2315 right eyes) (47.38% female) with a mean age of 4.52±0.88 years (range 3-6 years) were included. The magnitude and the ratio of three kinds of CA components did not change with aging (p=0.1233 and p>0.1, respectively). Though the axial distribution of RA remained unchanged with aging, a significant reduction in RA was seen in year 6 compared to that of year 3 and year 4 (p=0.036 and 0.041, respectively). Conversely,the ATR component in IA was lower in year 6 (68.02%) than it in year 3 (81.92%) and year 4 (77.12%) (both p<0.001) accompanied by increased frequency of oblique astigmatism in year 6 than it in year 3 and year 4 (p<0.001 and p=0.012,respectively). Negative relationship was found between IA and AL. Conclusion: RA decreased from year 3 to year 6. The shift of the axis in IA from ATR to Oblique and WTR may account for the reduction in RA. Eyes with shorter AL had larger IA. Keywords: Internal astigmatism; corneal astigmatism; axial length; with-the-rule.


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