A Case study on Hypermetropia in North Uttar Pradesh Population

India has done a very much towards to become a developed country but still India is a part of developing countries and for this reason most of the factors are responsible and from these one of the factor is poverty and their index. Poverty index, directly affect the standard of living in a population , that why various major and minor diseases are occur in the various age groups of people, and Hypermetropia is one of these that can occur due to unhealthy life style. Hyperopia, also termed hypermetropia or farsightedness, is a common refractive error in children and adults. Its effect on an individual and the symptoms produced varies greatly, depending on the magnitude of hyperopia, the age of the individual, the status of the accommodative and convergence system, and the demands placed on the visual system. Individuals with uncorrected hyperopia may experience symptoms such as blurred vision, asthenopia (e.g., headaches and eyestrain) while reading, accommodative/binocular dysfunction, amblyopia, and/or strabismus. This article outlines several discussion points as related to hyperopia: definition and classifications, prevention, clinical presentations, importance of early detection, examination techniques, risks of uncorrected hyperopia, and management strategies. Keywords: Amblyopia, Hyperopia, Refractive error, Strabismus, Visual development.

Low-code development and model-driven engineering: Two sides of the same coin?

The last few years have witnessed a significant growth of so-called low-code development platforms (LCDPs) both in gaining traction on the market and attracting interest from academia. LCDPs are advertised as visual development platforms, typically running on the cloud, reducing the need for manual coding and also targeting non-professional programmers. Since LCDPs share many of the goals and features of model-driven engineering approaches, it is a common point of debate whether low-code is just a new buzzword for model-driven technologies, or whether the two terms refer to genuinely distinct approaches. To contribute to this discussion, in this expert-voice paper, we compare and contrast low-code and model-driven approaches, identifying their differences and commonalities, analysing their strong and weak points, and proposing directions for cross-pollination.

The reverse motion illusion in random dot motion displays and implications for understanding development

Across two independent developmental labs, we have been puzzled by the observation that a small proportion of our child and adult participants consistently report perceiving motion in the direction opposite to that presented in random dot motion displays, sometimes even when the motion is at 100% coherence. In this review, we first draw together existing reports of misperceptions of motion direction in random dot displays across observers in a small percentage of trials, before reporting evidence of consistent reverse motion perception in a minority of observers, including previously unreported observations from our own studies of visual development. We consider possible explanations for this reverse motion illusion, including motion induction, motion energy, correspondence noise and spatial undersampling. However, more work is required to understand the individual differences relating to this percept. We suggest that errors in perceived motion direction are likely to be more widespread than can be currently gleaned from the literature and explain why systematic study is needed, especially in children. Finally, we list some remaining open questions and call for collaborative efforts to document this phenomenon and stimulate future investigation.

Testing Stereopsis in Children

Stereopsis develops very early in life and is thought to be present in a normally developing child by six months of age. In order to develop stereopsis, multiple components of visual development must be intact including visual acuity and bifoveal fixation. Stereopsis is the most sensitive way to assess sensory fusion but can be unreliable in very young age groups due to difficulty understanding the test or instructions. It is best to choose an option with global stereopsis (high level cortical stereo), as local stereopsis may overestimate ability due to available monocular cues. Global is created using random dot stereograms (RDS) – computer-generated patterns to create a stereoscopic form, while local contains line stereograms which create horizontal retinal image disparity giving the perception of depth. Stereopsis can be affected by strabismus, amblyopia, and other binocular vision dysfunctions that interfere with visual efficiency (especially in school-age children). The chapter discusses the most commonly used clinical tests of global and local stereopsis.

The Effect of Optical Defocus on the Choroidal Thickness: A Review

The choroid is a heavily vascularized tissue located between the retina and sclera and plays a primary role in ocular metabolism. It has recently been suggested that the choroid has the ability to change its thickness and secretion of growth factors. This may play an important role during visual development by adjusting retinal position during growth to support emmetropisation; however, the mechanism by which changes in choroidal thickness (ChT) occur is unclear. This relationship becomes an interesting topic in the clinical field, although conflicting evidence found that these changes in the choroidal thickness may not be associated with the development of refractive errors. Many reports have investigated the changes in the choroid and related factors that affect the ChT. Thus, this review will summarize the current literature related to choroidal thickness in different refractive error groups, determine the factors that influence the thickness of the choroid, and discuss in detail the relationship between the changes in the ChT and ocular elongation, and therefore, the effect of optical defocus on ChT and the development of the refractive error.

Expression of SCO1 and SCO2 after form-deprivation myopia in Guinea pigs

Purpose The retina is a highly energy-consuming tissue associated with visual development, and the reduced quality of retinal imaging can be related to myopia. Synthesis of cytochrome c oxidase 1 ( SCO1) and synthesis of cytochrome c oxidase 2 ( SCO2) are involved in ATP (adenosine triphosphate) synthesis and energy metabolism. This study aimed to observe the morphologic changes and investigate the expression of SCO1 and SCO2 induced by form-deprivation myopia (FDM) in the retina and sclera of guinea pigs. Methods Thirty-six 3-week-old male guinea pigs were randomly assigned to one of two groups: (1) the model group (n = 18), in which the right eyes were covered by a thin opaque balloon as FDM group, and the left eyes were uncovered and served as the contralateral control group; (2) the blank control group (n = 18), in which bilateral eye received no manipulation. Eyeballs were enucleated for histological analysis. The retina and sclera of the guinea pigs were separated to determine the protein and mRNA expression levels of SCO1 and SCO2, respectively. Results After four weeks of form deprivation (FD), the refractive degree and axial length increased significantly ( P < 0.001). The retinal and scleral tissues were moderately thinner, and the ganglion cells and the cells of inner and outer nuclear layers in the retina became fewer. Compared with the contralateral control group ( P < 0.001) and the blank control group ( P < 0.001), the collagen content of the sclera became less in the FDM group. The protein and mRNA expression levels of SCO1 and SCO2 in the FDM group were significantly lower than those in the contralateral control group and the blank control group ( P < 0.05). Conclusions The morphologies of the retina and sclera were changed, and the expression of SCO1 and SCO2 at the protein and transcription levels was significantly reduced in the FDM group. Given these changes, SCO1 and SCO2 genes may be involved in myopic progression.

Management of Abnormal Visual Developments

When human beings recognize the external world, more than 80% of the information come from visual function and visual system. Normal visual development and normal binocularity are the fundamental of good visual acuity and visual functions. Any abnormal visual experience would cause abnormality, such as refractive error, strabismus, amblyopia and other diseases. The patients with abnormal visual developments were reported to have abnormal, lonely, and other psycho problems. In this chapter, we will describe the normal developmental of visual function, summarize the abnormal developments and the correction or treatment.

Well-Designed Teaching Examples Influence the Outcome of Technology Acceptance: The Example of Next-Generation Art Process Learning

With the upgrade of hardware and the consumer experience, the application of high-standard digital art technology to produce finished products is the current trend of digital entertainment visual development, through the application of next-generation art technology, which has become the basis for the application of the 3D digital media art industry. Based on the technology acceptance model, this study measured student acceptance of next-generation art production software by surveying students in two school districts who took a next-generation art course that used blended learning and worked examples. Intention to use was also assessed using variables such as the type of graduation project and the number of credits in the student’s major course. A total of 104 valid questionnaires were obtained from four classes in the fourth year of college. Specifically, students’ perceived usefulness, perceived ease of use, and attitudes toward using next-generation art software were determined, and correlations between students’ acceptance of next-generation art use and their willingness to use next-generation art methods were explored. The worked examples increased the acceptance and willingness of students with poor 3D technical skills to use next-generation art, but also allowed them to overestimate their technical skills.

Refractive errors and risk factors for myopia in infants aged 1–18 months in Tianjin, China

Background Infancy is the of a child’s visual development. Refractive errors, especially myopia, are a common vision disorder. Thus, the purpose of this study was to explore refractive errors and risk factors for myopia among infants aged 1–18 months in Tianjin, China. Methods A total of 583 infants aged 1–18 months participated in this cross-sectional study at Tianjin Women’s and Children’s Health Center in China from February 2019 to November 2020. Each infant received a complete ophthalmologic examination, and myopia-related risk factors were investigated using a questionnaire. Results A total of 583 eligible infants participated in this study, including 312 (53.5%) boys and 271 (46.5%) girls. There were 164 (28.1%) premature born infants. The mean age was 6.59 ± 4.84 months (range, 1–18 months). The mean spherical equivalent (MSE) for the right eye was 1.81 D ± 1.56 D, with no difference related to sex (P = 0.104). Refractive state showed an average hyperopia of +2.74 ± 1.74 D at early ages, followed by a trend toward less hyperopia, finally reaching +1.35 ± 1.44 D at the age of 18 months (P ≤0.001). The overall prevalence rates of myopia (MSE ≤ −0.50 D), emmetropia (−0.50 D<MSE<+0.50 D), hyperopia (MSE ≥ +2.00 D), and astigmatism (≥ 1.50 D) were 5.1%, 10.8%, 42.7%, and 49.9%, respectively. The chi-square tests showed that gender, gestational age ≥37 weeks, winter birth, prenatal exposure to environmental tobacco smoke, and parental history of high myopia were associated with children’s myopia (P = 0.022, P = 0.023, P = 0.038, P = 0.015, P<0.001, respectively). Conclusions Among Chinese infants in Tianjin, hyperopia and astigmatism were the most frequent refractive errors, and the diopter was lower in individuals with higher age. In a small number of infants with myopia, genetic factors and the prenatal environment were associated with the early onset of myopia.

Visual development of healthy full-term infants under 24 months of age using the Preverbal Visual Assessment (PreViAs) questionnaire

As visual perception development proceeds rapidly after birth, early detection of developmental maturity is required. Healthy infants do not have many opportunities for visual perception evaluation, so a reliable evaluation method is necessary. This retrospective study included 276 healthy full-term infants less than 24 months of age using the Preverbal Visual Assessment (PreViAs) questionnaire, which measures scores of subdivided age groups for the global scores and four domains: visual attention (VA), visual communication (VC), visual-motor coordination (VMC) and visual processing (VP). Through this study, reference values and cut-off scores of the PreViAs questionnaire were presented, reliability was secured, and potential influencing factors of the PreViAs scores were analyzed. Using Cronbach's α coefficient, the global scores were 0.938, 0.781 for VA, 0.660 for VC, 0.874 for VMC, and 0.942 for VP. The internal consistency of the questionnaire was high in the global scores and three domains (VA, VMC, VP). In infants under 12 months, the global scores and the VA, VMC, and VP domains showed positive association with gestational age, whereas the VC domain positively correlated with sex: which was found to be greater for females (P<0.05). In those 12 month and above, no clinical factors were significantly associated with the PreViAs scores in all domains. The PreViAs questionnaire is a useful tool for visual assessment of healthy full-term infants under 24 months of age, suggesting reference values and cut-off scores according to age, and estimating the maturation age for visual perception development of each domain.