scholarly journals CAUSES OF DEATH IN PATIENTS WITH DIABETES MELLITUS, THYROID DISORDERS AND OBESITY: A CLINICIAN’S PERSPECTIVE

2019 ◽  
Vol 4 (4) ◽  
pp. 13-21
Author(s):  
E. G. Starostina
Keyword(s):  
Diabetes Mellitus ◽  
Thyroid Disease ◽  
Causes Of Death ◽  
Point Of View ◽  
Endocrine Disorders ◽  
Thyroid Disorders ◽  
Associated Diseases ◽  
Patients With Diabetes

The paper presents the point of view of an endocrinologist to causes of death in patients with most prevalent endocrine disorders, such as thyroid disease, diabetes mellitus and obesity. The author critically analyzes the trends of the last years in the principles of registration of causes of death in diabetes mellitus, emphasizing the need to differentiate between “associated diseases” and “etiologically related diseases”.

The Relationship of Metabolic and Endocrine Parameters with Associated Diseases in Diabetes Mellitus

2018 ◽  
Vol 69 (5) ◽  
pp. 1288-1291 ◽  
Author(s):  
Mariana Cornelia Tilinca ◽  
Sandor Pal ◽  
Zoltan Preg ◽  
Eniko Barabas Hajdu ◽  
Raluca Tilinca ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Scoring System ◽  
Laboratory Tests ◽  
Treatment Plan ◽  
Individual Treatment ◽  
Diabetic Patients ◽  
Thyroid Disorders ◽  
Associated Diseases ◽  
Investigation Methods ◽  
Predictive Role

The most common comorbidities in patients with diabetes mellitus are cardiovascular diseases, obesity, dyslipidemia, thyroid disorders but other associated diseases may frequently occur. Laboratory tests are useful investigation methods that may reveal the subclinical manifestations of the disease but they are also essential for patient monitoring. The aim of the study was to assess laboratory parameters and associated diseases in diabetic subjects and to implement a scoring system with a predictive role in the evolution of the cases. Material and methods: The study group consisted of 195 subjects with documented type 1 or type 2 diabetes. About half of the cases were collected from the Procardia outpatient unit, and the rest were patients admitted to the Diabetology Clinic in T�rgu Mure�. The study was performed between January - June 2017. The results of the laboratory tests, as well as the information regarding comorbidities and treatment, was collected and patients� body mass index was calculated. Based on the clinical data, a scoring system, called Diabetes Complication Severity Index (DCSI) with a predictive role, was implemented. The diabetic outpatients presented significantly better carbohydrate metabolic balance compared to the hospitalized subjects. No significant differences could be observed regarding kidney function, hepatic status and lipid profile of the two subgroups of diabetic subjects. The most important comorbidity observed in both patient groups was arterial hypertension. The hospitalized diabetic subjects had significantly higher incidence of ischemic heart disease and significantly lower incidence of thyroid disorders compared to the outpatients. The DCSI scoring system revealed that comorbidities are more frequently present in the hospitalized patients compared to the ambulant diabetic subjects. Evaluation of clinical status and laboratory results in diabetic patients followed by implementation of a scoring system based on the data obtained regarding comorbidities could help clinicians to set up an individual treatment plan for these patients, focusing on preventing other complications.

scholarly journals Thyroid hormones profile of patients with type 2 diabetes mellitus in Kano, Nigeria

2020 ◽  
Vol 3 (1) ◽  
Author(s):  
Mustapha Zainab Abubakar ◽  
Kabiru Abdulsalam ◽  
Isah A. Yahaya
Keyword(s):  
Diabetes Mellitus ◽  
Thyroid Dysfunction ◽  
Cross Sectional Study ◽  
Endocrine Disorders ◽  
Cross Sectional ◽  
Type 2 Dm ◽  
Type 2 Diabetics ◽  
Patients With Diabetes ◽  
Considerable Impact

Diabetes mellitus (DM) and thyroid disease are the two most common endocrine disorders in the general population. Several Studies have shown that thyroid dysfunction is common in patients with DM, and thyroid dysfunction have been found to have a considerable impact on the glycaemic control and often increases the risk of development of long-term complications in patients with diabetes mellitus. This study determined the prevalence of thyroid dysfunction in patients with type 2 DM in Kano, North-Western Nigeria. The study was a descriptive cross-sectional study conducted on 250 participants made up of 130 patients with type 2 DM and 120 apparently healthy non-diabetic controls. Questionnaires were used to collect information on bio data, medical history, duration of diagnosis of diabetes and type of treatment. Also, blood samples of the participants were collected and analyzed for fasting plasma glucose, fT3, fT4, and TSH. The results were interpreted using American Thyroid Associations’ criteria and the data was analyzed using the statistical software package, STATA version 20. Two hundred and thirty-four (93.6%) of the participants were euthyroid while sixteen (6.4%) were found to have various forms of thyroid dysfunction. The prevalence of thyroid dysfunction was 10% and 2.5% among type 2 diabetics and controls respectively. Among the type 2 DM patients with thyroid dysfunction, 38.5% had hypothyroidism. Thyroid dysfunction was found to be commoner among type 2 DM patients than non-diabetic individuals with hypothyroidism being the commonest disorder.

scholarly journals Endocrine Disorders in a Specialized Hospital in Guyana

2019 ◽  
pp. 30-31
Author(s):  
Yaquelin Gonzalez Ricardo ◽  
Yaritza Lopez Diaz ◽  
Ravendra Johnaton Dudnauth ◽  
Maritza Oliva Perez
Keyword(s):  
Diabetes Mellitus ◽  
Pituitary Tumors ◽  
Obstetric Care ◽  
Endocrine Disorders ◽  
Patients With Diabetes ◽  
Sheehan Syndrome ◽  
One Year ◽  
The One ◽  
Low Prevalence ◽  
Endocrinology Clinic

Background: Endocrine diseases are characterized by hormonal alterations (excess or defect). Due to the low prevalence (less than five case 5 / 10 000 inhabitants), a large number of them, qualify to be classified as rare diseases such as those of organs like: hypophysis, adrenal glands, gonads as well as some congenital thyroid diseases. Others like Diabetes are considering almost epidemic. Objective: To define the types of diseases observed in the only Endocrinology Clinic in Guyana. Methods: The diagnoses of all patients who attended the endocrinology clinic of the Georgetown Public Hospital Corporation from June 1, 2016 to May 31, 2017, were analyzed. Results: During the one year of this study, approximately 639 patients attended the endocrinology clinic. Of this, 178 patients had thyroid-related diseases with 80 of these having thyrotoxicosis, 49 having hypothyroidism followed by 110 patients with diabetes mellitus. Pituitary tumors were also diagnosed with 2 of acromegaly and 6 of prolactinomas. Cases of hypoadrenalism (n = 5), hypogonadism (n = 4), and pheochromocytoma (n = 6) were not rare; gonadal disease were also found in 17 patients. Thyroid disease was the most frequent diagnosis followed by diabetes mellitus. New emerging endocrine disorders such as hyperlipidemia (n = 1) were rare. Some persons attending the clinic were also noted to be overweight /obese however this was not the primary reason for joining the clinic. Traditional diseases such as Sheehan Syndrome have become rare due to improvements in Obstetric care. 

scholarly journals Thyroid Disorders and Diabetes Mellitus

2011 ◽  
Vol 2011 ◽  
pp. 1-7 ◽  
Author(s):  
Mirella Hage ◽  
Mira S. Zantout ◽  
Sami T. Azar
Keyword(s):  
Diabetes Mellitus ◽  
Glucose Control ◽  
Systematic Approach ◽  
Endocrine System ◽  
Thyroid Disorders ◽  
Patients With Diabetes

Studies have found that diabetes and thyroid disorders tend to coexist in patients. Both conditions involve a dysfunction of the endocrine system. Thyroid disorders can have a major impact on glucose control, and untreated thyroid disorders affect the management of diabetes in patients. Consequently, a systematic approach to thyroid testing in patients with diabetes is recommended.

scholarly journals Self-reported endocrine late effects in adults treated for brain tumours, Hodgkin and non-Hodgkin lymphoma: a registry based study in Northern Germany

2015 ◽  
Vol 173 (2) ◽  
pp. 139-148 ◽  
Author(s):  
Judith Gebauer ◽  
Eva-Maria Fick ◽  
Annika Waldmann ◽  
Thorsten Langer ◽  
Ilonka Kreitschmann-Andermahr ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Hodgkin Lymphoma ◽  
Late Effects ◽  
Psychological Status ◽  
Endocrine Disorders ◽  
German Population ◽  
Thyroid Disorders ◽  
Northern Germany ◽  
Non Hodgkin Lymphoma ◽  
The Impact

ObjectiveDue to the increasing success and survival rates in the primary treatment of malignancies derived from the CNS as well as the hematopoietic system, endocrine late effects of cancer and its therapy are of growing importance. Despite evaluation of these late effects in patients treated for cancer in childhood, the impact on adults remains largely unclear.Methods1035 adult patients primarily diagnosed with a CNS malignancy, a Hodgkin (HL) or non-Hodgkin lymphoma (NHL) between 1998 and 2008 were recruited via the regional epidemiological cancer registry covering ∼2.8 million inhabitants in the federal state of Schleswig-Holstein, Northern Germany. The prevalence of endocrine disorders and current psychosocial impairment was assessed employing several questionnaires (SF-36v1, WHO-5).ResultsFully completed questionnaires of 558 patients were available for subsequent analysis showing markedly reduced overall performance and psychological status when compared to German reference data. Thyroid disorders were reported in 16.3% of patients with 10.4% suffering from hypo- and 5.9% from hyperthyroidism. Overall, 17.6% stated to be affected by diabetes mellitus with an increased rate of 21.1% among NHL patients and 11.5% of participants were affected by osteoporosis.ConclusionCompared to German population based studies on the prevalence of diabetes mellitus, osteoporosis and thyroid disorders the frequency of all these endocrine problems was significantly increased in CNS, HL, and NHL cancer survivors. These data confirm that not only children and adolescents but also adult cancer patients are at risk for therapy associated endocrine late effects.

scholarly journals EVALUATION OF ASSOCIATION BETWEEN AGE, GENDER,DURATION OF DIABETES MELLITUS AND HBA1C WITH THYROID PROFILE IN DIABETES MELLITUS PATIENTS

2020 ◽  
Vol 4 (11) ◽  
Author(s):  
Bhaskar MK ◽  
Sanjay Zachariah ◽  
Annette Menezes
Keyword(s):  
Diabetes Mellitus ◽  
Diabetic Patients ◽  
Thyroid Disorders ◽  
Exclusion Criteria ◽  
Duration Of Diabetes ◽  
Study Results ◽  
Patients With Diabetes ◽  
And Gender ◽  
Thyroid Profile ◽  
Hypothyroid Patients

Background: Diabetes mellitus can be observed in any age group and gender. If it is not treated on time, it can lead to development of other disorders. The present study aims to evaluate the association of age, gender, duration of diabetes and HbA1C with thyroid profile in patients with diabetes mellitus. Materials and Methods: The study included 100 diabetic patients based on the inclusion and exclusion criteria. The study protocol was explained to each patient and informed consent was obtained. All the patients demographic and clinical data was recorded and analysed. SPSS (16.0) version used for analysis. Results: Patients between 41-50 years of age showed more of hypothyroid profile. Males are less prone to thyroid disorders compared to females. Patients with DM less than 10 years showed hypothyroid profile. Maximum hypothyroid patients showed HbA1C level less than 7%. Conclusion: The study results conclude that as age progresses, females are more prone to thyroid disorders compared to males. Keywords: Age, Diabetes Mellitus, Thyroid, Gender, HbA1C, Euthyroid

scholarly journals Study on Thyroid Dysfunction in Patients with Type-2 Diabetes

2020 ◽  
Vol 7 (52) ◽  
pp. 3142-3147
Author(s):  
Senthil Chander ◽  
Kalpana Dev Venkatesan ◽  
Christina Mary Paul
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Subclinical Hypothyroidism ◽  
Thyroid Dysfunction ◽  
General Medicine ◽  
Diabetic Patients ◽  
Endocrine Disorders ◽  
Cross Sectional ◽  
Patients With Diabetes

BACKGROUND Diabetes mellitus is one of the leading endocrine disorders worldwide. Thyroid dysfunction is a common endocrine disorder affecting the general population next to diabetes. The objective of this study was to determine the prevalence of thyroid dysfunction among patients with Type 2 diabetes. METHODS This analytical cross sectional study was conducted from June 2019 to Dec 2019. One hundred and fifty type–2 diabetes patients who attended the outpatient clinic of General Medicine Department, ACS Medical College and Hospital were included in the study. A detailed history and examination was done after getting informed consent. Blood samples were collected and sent to the laboratory for the evaluation of thyroid profile. RESULTS Thyroid dysfunction was found in 27 % of the patients with diabetes. Subclinical hypothyroidism was the most common thyroid dysfunction reported (14.7 %) followed by clinical hypothyroidism (10 %), subclinical hyperthyroidism (2 %) and clinical hyperthyroidism (0.6 %). CONCLUSIONS Thyroid dysfunction is common in patients with type-2 diabetes. A substantial proportion of the diabetic patients with thyroid dysfunction have subclinical hypothyroidism. Unidentified thyroid dysfunction could negatively impact diabetes and its complications. Therefore, early and routine screening of thyroid is recommended in all patients with diabetes to reduce the burden of the disease. KEYWORDS Type-2 Diabetes Mellitus, Thyroid Dysfunction, Hypothyroidism

scholarly journals Consensus position of endocrinologists and pathologists on coding causes of death in patients with diabetes mellitus (expert opinion)

2021 ◽  
Vol 24 (3) ◽  
pp. 300-309
Author(s):  
I. I. Dedov ◽  
G. A. Frank ◽  
N. G. Mokrisheva ◽  
M. V. Shestakova ◽  
G. A. Melnichenko ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Russian Federation ◽  
Causes Of Death ◽  
Prime Minister ◽  
Negative Impact ◽  
Mortality Risks ◽  
Deputy Prime Minister ◽  
Patients With Diabetes ◽  
Icd 10 ◽  
The Russian Federation

Coding of the causes of death of patients with diabetes mellitus (DM) in the Russian Federation is one of the long-discussed problems, due to the comorbidity of diabetes and cardiovascular diseases (CVD) and a number of contradictions in the key regulatory documents regulating the statistics of mortality in this category of patients, which acquires particular relevance in the context of the coronavirus pandemic, due to its negative impact on the outcomes of the course of COVID-19 and mortality risks. In pursuance of the decisions of the Minutes of the meeting of the working group under the project committee of the National Project «Health» on identifying patterns in the formation of mortality rates of the population dated January 20, 2021 No. 1, chaired by Deputy Prime Minister of the Russian Federation T.A. Golikova, experts of two directions - endocrinology and pathological anatomy, prepared a Draft of agreed recommendations on the Rules for coding the causes of death of patients with diabetes, causing the greatest problems in terms of the use of ICD-10 when choosing the initial cause of death, including in the case of death from CVD and COVID-19.

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