scholarly journals Thyroid hormones profile of patients with type 2 diabetes mellitus in Kano, Nigeria

2020 ◽  
Vol 3 (1) ◽  
Author(s):  
Mustapha Zainab Abubakar ◽  
Kabiru Abdulsalam ◽  
Isah A. Yahaya
Keyword(s):  
Diabetes Mellitus ◽  
Thyroid Dysfunction ◽  
Cross Sectional Study ◽  
Endocrine Disorders ◽  
Cross Sectional ◽  
Type 2 Dm ◽  
Type 2 Diabetics ◽  
Patients With Diabetes ◽  
Considerable Impact

Diabetes mellitus (DM) and thyroid disease are the two most common endocrine disorders in the general population. Several Studies have shown that thyroid dysfunction is common in patients with DM, and thyroid dysfunction have been found to have a considerable impact on the glycaemic control and often increases the risk of development of long-term complications in patients with diabetes mellitus. This study determined the prevalence of thyroid dysfunction in patients with type 2 DM in Kano, North-Western Nigeria. The study was a descriptive cross-sectional study conducted on 250 participants made up of 130 patients with type 2 DM and 120 apparently healthy non-diabetic controls. Questionnaires were used to collect information on bio data, medical history, duration of diagnosis of diabetes and type of treatment. Also, blood samples of the participants were collected and analyzed for fasting plasma glucose, fT3, fT4, and TSH. The results were interpreted using American Thyroid Associations’ criteria and the data was analyzed using the statistical software package, STATA version 20. Two hundred and thirty-four (93.6%) of the participants were euthyroid while sixteen (6.4%) were found to have various forms of thyroid dysfunction. The prevalence of thyroid dysfunction was 10% and 2.5% among type 2 diabetics and controls respectively. Among the type 2 DM patients with thyroid dysfunction, 38.5% had hypothyroidism. Thyroid dysfunction was found to be commoner among type 2 DM patients than non-diabetic individuals with hypothyroidism being the commonest disorder.

scholarly journals Study on Thyroid Dysfunction in Patients with Type-2 Diabetes

2020 ◽  
Vol 7 (52) ◽  
pp. 3142-3147
Author(s):  
Senthil Chander ◽  
Kalpana Dev Venkatesan ◽  
Christina Mary Paul
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Subclinical Hypothyroidism ◽  
Thyroid Dysfunction ◽  
General Medicine ◽  
Diabetic Patients ◽  
Endocrine Disorders ◽  
Cross Sectional ◽  
Patients With Diabetes

BACKGROUND Diabetes mellitus is one of the leading endocrine disorders worldwide. Thyroid dysfunction is a common endocrine disorder affecting the general population next to diabetes. The objective of this study was to determine the prevalence of thyroid dysfunction among patients with Type 2 diabetes. METHODS This analytical cross sectional study was conducted from June 2019 to Dec 2019. One hundred and fifty type–2 diabetes patients who attended the outpatient clinic of General Medicine Department, ACS Medical College and Hospital were included in the study. A detailed history and examination was done after getting informed consent. Blood samples were collected and sent to the laboratory for the evaluation of thyroid profile. RESULTS Thyroid dysfunction was found in 27 % of the patients with diabetes. Subclinical hypothyroidism was the most common thyroid dysfunction reported (14.7 %) followed by clinical hypothyroidism (10 %), subclinical hyperthyroidism (2 %) and clinical hyperthyroidism (0.6 %). CONCLUSIONS Thyroid dysfunction is common in patients with type-2 diabetes. A substantial proportion of the diabetic patients with thyroid dysfunction have subclinical hypothyroidism. Unidentified thyroid dysfunction could negatively impact diabetes and its complications. Therefore, early and routine screening of thyroid is recommended in all patients with diabetes to reduce the burden of the disease. KEYWORDS Type-2 Diabetes Mellitus, Thyroid Dysfunction, Hypothyroidism

scholarly journals Adherencia terapéutica y control metabólico en pacientes con diabetes mellitus tipo 2 / adherence and metabolic control in patients with type 2 diabetes mellitus in a hospital of medellin (colombia), 2011

2014 ◽  
Vol 14 (1) ◽  
pp. 44-50
Author(s):  
Lina María Martínez Sánchez ◽  
Gloria Inés Martínez Domínguez ◽  
María de los angeles Rodríguez Gázquez ◽  
Camilo andrés Agudelo Vélez ◽  
Juan Guillermo Jiménez Jiménez ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Therapeutic Adherence ◽  
Type 2 Dm ◽  
Patients With Diabetes ◽  
Apoyo Social ◽  
The Relationship

Objetivo:Explorar la relación entre la adherencia terapéutica y el control metabólicoen pacientes con Diabetes Mellitus tipo 2 (DM-2), que consultaron a una instituciónhospitalaria en Medellín-Colombia.Materiales y métodos:Estudio transversal. Lamuestra estuvo constituida por personas con 18 y más años, con diagnóstico de DM-2•PHVHVTXHILUPDURQHOFRQVHQWLPLHQWRLQIRUPDGR(OPXHVWUHRIXHQRSUREDELOtVWLFRmuestra por conveniencia. Se aplicaron las escalas Summary of Diabetes Self-CareActivities para valorar adherencia terapéutica y Duke-Unc para evaluar apoyo social.La hemoglobina glicosilada (HbA1c) fue procesada por el método inmunoturbidimé-trico de inhibición en el Equipo Cobas C-501. Se asumió como “control metabólicoadecuado” un valor de HbA1c < al 7%. Se utilizó el programa SPSS versión 19.0 parael análisis.Resultados:De los 70 pacientes estudiados: el 66% son mujeres, el 76%tiene Hipertensión arterial, el 70% tiene dislipidemias y el 16% fuma. Además, el 59%HVLQVXOLQRGHSHQGLHQWHHOWLHQH+E$F•HOQRWLHQHDSRRVRFLDO/RVfactores con mayor proporción de adherencia fueron: medicación (79%), cuidado depies (71%). Mientras que los más bajos fueron: autocontrol glicémico (32%) y ejercicio(28%). La HbA1c se correlacionó significativamente (p<0.05) con adherencia a dieta,autocontrol de glicemia, cuidado de pies, apoyo social y género.Conclusiones:Laadherencia terapéutica estuvo asociada al control metabólico en pacientes con DM-2. Objective: Explore the relationship between the therapeutic adherence and metaboliccontrol in patients with Diabetes Mellitus type 2 (DM-2), which consulted to a hospitalinstitution in Medellin-Colombia. Materials and Methods: Cross-sectional study. The

scholarly journals Thyroid Disorders Among People with Type 2 Diabetes in Misan Province: Prevalence Study

2021 ◽  
Vol 12 (1) ◽  
pp. 88-92
Author(s):  
Rasha K Khudhur ◽  
Ishraq J. Hasan ◽  
Maysaa Ghazi ◽  
Malik M. Hasan
Keyword(s):  
Diabetes Mellitus ◽  
Family History ◽  
Thyroid Dysfunction ◽  
Cross Sectional Study ◽  
Diabetic Patients ◽  
Endocrine Disorders ◽  
Thyroid Disorders ◽  
Cross Sectional ◽  
Rural And Urban

Diabetes mellitus type 2 (DMT2) with thyroid disorders are common endocrine disorders, and both of them mostly come close in any clinical practice. Hormones of the thyroid gland can influence carbohydrate metabolism. On the other side, there is a degree of insulin resistance in DMT2. The study aimed is to determine the prevalence of thyroid dysfunctions in DMT2.  A cross-sectional study was done enrolling 100 participants included, (n= 40) men, and (n= 60) women, their age ranged between 20-90 years old. Evaluation for thyroid status and assessment of T3, T4, and TSH levels were done. The results were 60% euthyroid, 33% hypothyroid, and 7% hyperthyroid cases from 100 patients with diabetes mellitus; among them, 17% in young adults, 49% in middle age, and 34% in the old age patients, the diabetic patients' results comprised between both sexes were 40% male and 60% females. In a comparison between rural and urban patients, the results were 44% rural and 56% urban. The study found there's 22% of thyroid dysfunction patients were with family history, and 42% of DM patients with family history, besides, there is 28% of patients suffered from hypertension and 33% of patients were smokers. So, the study showed a high prevalence of dysfunction among those with DMT2, especially hypothyroidism. Family history and DM might be pre-existing factors to the development of thyroid dysfunction. Hypertension and tobacco smoking might be a risk factor for thyroid dysfunction.

scholarly journals Diabetic kidney disease in patients with type 2 diabetes mellitus: a cross-sectional study

2021 ◽  
Vol 22 (1) ◽  
Author(s):  
Randa I. Farah ◽  
Mohammed Q. Al-Sabbagh ◽  
Munther S. Momani ◽  
Asma Albtoosh ◽  
Majd Arabiat ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Kidney Disease ◽  
Diabetic Kidney Disease ◽  
Laboratory Data ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Diabetic Kidney ◽  
Type 2 Dm

Abstract Aim Diabetic kidney disease (DKD) is a major long-term complication of diabetes mellitus (DM). Given the paucity of data on DKD in Jordan, we aimed to evaluate the prevalence, characteristics and correlates of DKD in Jordanian patients with type 2 DM. Methods This cross-sectional study included 1398 adult patients with type 2 DM who sought medical advice in the endocrinology clinic between March and September 2019. Demographic, clinical and laboratory data were reviewed. DKD was defined as reduced eGFR, and/or albuminuria. Three regression models were constructed to identify factors associated with CKD stages, albuminuria and DKD. Results Overall, 701 (50.14%) patients had DKD, with a median age of 59.71 ± 11.36  years. Older age, high triglycerides, and low high-density lipoprotein were associated with DKD (multivariable odds ratio [OR]: 1.02, 95% confidence interval [CI]: 1.01–1.03, p < 0.01; OR: 1.1, 95% CI: 1.01–1.2; and OR: 0.98, 95% CI: 0.97–0.99, p < 0.01 respectively). Metformin and renin-angiotensin system blockers were negatively associated with albuminuria and chronic kidney disease stages (p < 0.01). Conclusion Our study demonstrated that approximately one half of patients with type 2 DM had DKD. Further studies are necessary to understand this high prevalence and the underlying factors. Future research are needed to assess implementing targeted community-based intervention.

scholarly journals Association between obesity and depression in patients with diabetes mellitus type 2; a study protocol

F1000Research ◽  
2015 ◽  
Vol 4 ◽  
pp. 7 ◽  
Author(s):  
Eduardo De la Cruz-Cano ◽  
Carlos Alfonso Tovilla-Zarate ◽  
Emilio Reyes-Ramos ◽  
Thelma Beatriz Gonzalez-Castro ◽  
Isela Juarez-Castro ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Diabetes Mellitus Type 2 ◽  
Cross Sectional Study ◽  
Diabetes Mellitus Type ◽  
Sectional Study ◽  
Cross Sectional ◽  
The World ◽  
Patients With Diabetes

Background: Diabetes mellitus and depression are highly prevalent conditions throughout the world and have significant impact on health outcomes. It has been estimated that diabetes mellitus type 2 affects about 246 million people in the world; nevertheless, incidence varies among countries. There is evidence that depression is associated with a poor metabolic control in patients with type 2 diabetes mellitus that present other health problems (such as hypertension and obesity). The aim of this study protocol is to determine if obesity increases the risk for depression in patient with diabetes type 2.Methods: The analysis will be reported following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA).The studies suitable for inclusion will be assessed by the Newcastle-Ottawa Scale (NOS) to determine their methodological quality. To identify the studies of interest, we will search on PubMed and EBSCO databases. We will use the following keyword combinations: "Diabetes Mellitus type 2 AND obesity AND depression", "depression AND Diabetes Mellitus type 2", "Diabetes Mellitus type 2 AND body mass index cross sectional study", "depression AND obesity cross-sectional study". Causes for exclusion will be publications that studied patients diagnosed with diabetes mellitus type 1; articles that focused on the treatment and complications of diabetes mellitus type 2; publications that have studied other clinical or psychiatric conditions (for instance, seizure disorder or history of schizophrenia, bipolar disorder, psychotic symptoms or dementia).Conclusion: The results of this study will form the basis for a better understanding of the association between obesity and depression in patients with diabetes mellitus type 2, and will allow development of prediction tools and better interventions. It is evident that several modifiable and non-modifiable risk factors play an important role in the pathogenesis of diabetes among population. Currently, evidence for the deleterious effects of diabetes mellitus type 2 are based on cross-sectional or other observational designs. Therefore, this study will have important implications for future research and public health guidance.

scholarly journals Dietary Attitude of Adults with Type 2 Diabetes Mellitus in the Kingdom of Saudi Arabia: A Cross-Sectional Study

Medicina ◽  
2020 ◽  
Vol 56 (2) ◽  
pp. 91 ◽  
Author(s):  
Waqas Sami ◽  
Khalid M Alabdulwahhab ◽  
Mohd Rashid Ab Hamid ◽  
Tariq A. Alasbali ◽  
Fahd Al Alwadani ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Saudi Arabia ◽  
Dietary Behavior ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Kingdom Of Saudi Arabia ◽  
Cross Sectional ◽  
Patients With Diabetes

Background and Objectives: There is a paucity of literature on the dietary attitude (DA) of patients with type 2 diabetes in the Kingdom of Saudi Arabia (KSA). Although the prevalence of diabetes mellitus (DM) is high in Gulf countries, there remains a lack of understanding of the importance of dietary behavior in diabetes management among patients. Understanding the behavior of patients with diabetes towards the disease requires knowledge of their DA. Therefore, this study aimed to assess and evaluate the DA of type 2 diabetes patients, and it is the first of its kind in the KSA. Material and Methods: An analytical cross-sectional study was conducted among 350 patients with type 2 diabetes. A self-administered DA questionnaire was used to collect the data. Psychometric properties of the questionnaire were assessed by face validity, content validity, exploratory factor analysis, and internal consistency reliability. The data were collected using a systematic random sampling technique. Results: The overall DA of the patients was inappropriate (p = 0.014). Patients had an inappropriate DA towards food selection (p = 0.003), healthy choices (p = 0.005), food restraint (p < 0.001), health impact (p < 0.001), and food categorization (p = 0.033). A poor DA was also observed in relation to the consumption of red meat (p <0.001), rice (p < 0.001), soup and sauces (p = 0.040), dairy products (p = 0.015), and junk food (p < 0.001). Conclusions: It is highly recommended that patients with diabetes receive counseling with an empowerment approach, as this can bring about changes in their dietary behavior, which is deeply rooted in their daily routine. Healthcare providers should also be well-informed about patients’ attitudes and beliefs towards diabetes to design tailored educational and salutary programs for this specific community. Diabetes self-management educational programs should also be provided on a regular basis with a special emphasis on diet and its related components.

scholarly journals The Palmar Dermatoglyphic Patterns in Type II Diabetes Mellitus Cases- A Study in South Indian Population

2021 ◽  
Vol 14 (01) ◽  
pp. 379-383
Author(s):  
Akshai Lekshmi P ◽  
T Srimathi ◽  
V S Anandarani
Keyword(s):  
Diabetes Mellitus ◽  
Early Diagnosis ◽  
Type Ii Diabetes Mellitus ◽  
Cross Sectional Study ◽  
South Indian Population ◽  
Cross Sectional ◽  
Type 2 Dm ◽  
South Indian ◽  
Group A

Diabetes mellitus [DM] is a major disease worldwide with increasing prevalence. Its etiologic heterogeneity comprising genetic predisposition and environmental factors may provide a characteristic feature among the population helpful for the early diagnosis. This study aims to evaluate the palmar dermatoglyphic patterns in DM patients. This case controlled cross-sectional study included 100 type 2 DM patients in group A and 100 healthy subjects in group B. Each group has equal gender distribution. The palmar dermatoglyphics were evaluated quantitatively using standard methods. Student’s t-test and Chi-square test was used to determine the level of significance. The palmar triradius number varied significantly (Pd”0.0001). The angle of palm variations were statistically insignificant between groups, but TAD angle showed significant gender variations in group A patients (Pd”0.0001). The variation in palmar triradius revealed in this study may help in early diagnosis of type 2 DM patients and also may provide a scope for further studies with larger sample size.

scholarly journals Proteinuria Pasien Diabetes Melitus dan Obesitas Poli Penyakit Dalam RS Ibnu Sina Makassar

2019 ◽  
Vol 1 (1) ◽  
pp. 35-44
Author(s):  
Indah Lestari ◽  
Dzul Rizka ◽  
Prema Hapsari ◽  
Pratiwi L Basri ◽  
Nur Hidayah
Keyword(s):  
Diabetes Mellitus ◽  
Waist Circumference ◽  
Cross Sectional Study ◽  
P Value ◽  
Cross Sectional ◽  
Type 2 Dm ◽  
Class 1 ◽  
Obesity Patient ◽  
Prevalence Of Diabetes Mellitus

Background: The prevalence of diabetes mellitus in the world has increased which is certainly accompanied by a rapid increase in the incidence of its chronic complications like kidney disorders. Insulin resistance, the patophysiology of diabetes mellitus, also associated with obesity, which both are the main risk factors for cardiovascular events. Obesity also known as a risk factor for kidney disease that proved by the presence of proteinuria in obesity patients. Objective: To determine the correlation of obesity with occurrence of proteinuria in patients with type 2 DM in internal medicine polyclinic Ibnu Sina Hospital Makassar. Method: A cross sectional study on 32 type 2 DM patients at Ibnu Sina Hospital as measured by body weight, height and waist circumference. Urinalysis examination is also performed at that time. Results: In this study, there were 4 patients (12,5%) patients with proteinuria (+), 1 patient (3.1%) with proteinuria (++), 2 patients (6.3%) with proteinuria (+++) and 1 patient (3.1%) with proteinuria (++++). According to BMI, we found that 17 patients (53.1%) were overweight,  5 patients (15.6%) were class 1 obesity, no class 2 obesity patient, and 1 patients (3.1%) were class 3 obesity. In Waist circumference examination we found that  in normal waist circumference group there is 1 patient that did not has proteinuria while in the  abnormal waist circumference group, 8 patients out of 31 patients have proteinuria. After doing statistical analysis to assess the correlation of obesity with proteinuria obtained p value> 0.05. Similarly, the correlation analysis waist circumference with proteinuria obtained p value> 0.05. Conclusion: There is no correlation between obesity and proteinuria as well as waist circumference and proteinuria correlation in type 2 DM patients.

scholarly journals Low Levels of Usual Physical Activity Are Associated with Higher 24 h Blood Pressure in Type 2 Diabetes Mellitus in a Cross-Sectional Study

2017 ◽  
Vol 2017 ◽  
pp. 1-8 ◽  
Author(s):  
Alessandra Teixeira Neto Zucatti ◽  
Tatiana Pedroso de Paula ◽  
Luciana Verçoza Viana ◽  
Rafael DallAgnol ◽  
Felipe Vogt Cureau ◽  
...  
Keyword(s):  
Physical Activity ◽  
Diabetes Mellitus ◽  
Blood Pressure ◽  
Type 2 Diabetes ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Type 2 Dm ◽  
Low Levels

The aim of this study is to evaluate the association between usual physical activity and 24 h blood pressure (BP) profile in people with type 2 diabetes mellitus (DM). This is a cross-sectional study of 151 participants with type 2 DM. Usual physical activity was assessed by step counting and self-reported questionnaire. BP was measured in office and by 24 h ambulatory BP monitoring (ABPM; 24 h, daytime and nighttime). Mean participant age was 61.1 ± 8.4 years, 64% was women, and mean duration of diabetes was 14.3 ± 8.5 years. Ninety-two percent of participants had hypertension, and office BP was 138 ± 18/78 ± 10 mmHg. Inverse correlations were observed between step count and 24 h BP (systolic, r=−0.186; p=0.022), daytime BP (systolic, r=−0.198; p=0.015), and nighttime BP (pulse pressure, r=−0.190; p=0.019). People were categorized into tertiles of daily step count, and the 1st tertile had higher 24 h systolic BP, daytime systolic BP, daytime mean BP, and daytime systolic BP load than those in the other tertiles, even after adjusting for age and HbA1c. Participants with type 2 DM and low levels of physical activity exhibit higher 24 h and daytime systolic ambulatory BP values as compared with those who performed more steps per day, even after adjustments for confounding factors.

Is there an HbA1c Threshold for Symptoms of Chronic Hyperglycemia?

2021 ◽  
Author(s):  
Nicolle Müller ◽  
Thomas Lehmann ◽  
Ulrich Alfons Müller ◽  
Christof Kloos
Keyword(s):  
Diabetes Mellitus ◽  
Safety Margin ◽  
Well Being ◽  
Cross Sectional Study ◽  
Cross Sectional ◽  
Chronic Hyperglycemia ◽  
Patients With Diabetes ◽  
The Mean

Abstract Aims of the study The minimum therapeutic goal regarding metabolic control for people with diabetes mellitus is the “absence of symptoms of hyperglycemia.” However, it is uncertain whether a level of HbA1c can be defined that guarantees the absence of these symptoms. The aim was to define an HbA1c threshold above which most patients show hyperglycemic symptoms. Methods In a multicenter cross-sectional study, 137 patients with type 1 and 285 with type 2 diabetes were asked about their symptoms during periods of hyperglycemia with a standardized questionnaire. Seventeen symptoms of hyperglycemia were summarized to the total hyperglycemia symptom score (THSS; min. 0; max. 68). The answers could be given according to the frequency and intensity in the last 4 – 6 weeks. Results The HbA1c threshold above which most patients showed hyperglycemic symptoms was 10.05% for patients with diabetes type 1 and 8.9%. for patients with type 2. Most confidence was reached on the symptoms of frequent urination” and “tiredness.” The mean THSS was 19.4 (±9.0) and showed a positive correlation with age (r=0.167; p<0.001) and HbA1c (r=0.254; p<0.001). Conclusions We identified an HbA1c threshold above which most patients show symptoms of hyperglycemia. In the treatment of people with diabetes mellitus, a safety margin to this threshold should be maintained to preserve well-being and avoid distress. However, since hyperglycemia symptoms are subject to many influencing factors, an adjustment of the therapy—both intensification and de-intensification—should always be carried out in combination with the requested hyperglycemia symptoms and HbA1c value.

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