scholarly journals Magnitude and Determinants of Opportunistic Infections Among Hiv/Aids Patients in Sphmmc, Addis Ababa, Ethiopia: Retrospective Study

2018 ◽  
Vol 4 (1) ◽  
Author(s):  
Deribe Addisu
Keyword(s):  
Retrospective Study ◽  
Opportunistic Infections ◽  
Addis Ababa ◽  
Aids Patients ◽  
Hiv Aids

scholarly journals PENGARUH PENDEKATAN MELALUI KONSELING INTERPERSONAL TERHADAP RESPON SOSIAL, EMOSIONAL DAN SPIRITUAL PADA PASIEN HIV/AIDS

2020 ◽  
Vol 8 (1) ◽  
pp. 62
Author(s):  
Indah Jayani ◽  
Fatma Sayekti Ruffaida
Keyword(s):  
Opportunistic Infections ◽  
Sampling Technique ◽  
Wilcoxon Test ◽  
P Value ◽  
Social Emotional ◽  
Aids Patients ◽  
Cross Sectional ◽  
Before And After ◽  
The Right ◽  
Hiv Aids

Approach to PLWHA by providing interpersonal counseling is the right thing to do to overcome psychological problems including social, emotional and spiritual aspects of PLWHA. This study aims to look at the effect of interpersonal counseling on social, emotional and spiritual responses in HIV/ AIDS patients. This research is a type of non-experimental research with a cross-sectional approach. The sample is post-test people and tested positive for HIV in the Kediri region, which is 32 with purpossive sampling technique. Data on social, emotional and spiritual responses were obtained based on the results of data recapitulation from the instrument in the form of a questionnaire. The results of the study with the non-parametric Wilcoxon test showed there were differences between social responses of HIV/AIDS patients before and after given interpersonal counseling with p value = 0,000, there were differences between the emotional responses of HIV/AIDS patients before being given interpersonal counseling and after being given counseling with p value = 0,000, and there is a difference between spiritual responses in HIV/AIDS patients before being given interpersonal counseling and after being given interpersonal counseling with p value = 0,000. It can be concluded that interpersonal counseling influences social, emotional and spiritual responses of HIV/AIDS patients. It is recommended that the mentoring of HIV/AIDS patients through interpersonal counseling can continue so as to enhance physiological responses that will have an impact on disease prognosis, prevention of opportunistic infections and reduce mortality rates for HIV patients/ AIDS.

scholarly journals Immunologic biomarkers, morbidity and mortality among HIV patients hospitalised in a Tertiary Care Hospital in the Brazilian Amazon

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Wellington Mota Gama ◽  
Carlos Henrique Michiles Frank ◽  
Taynná Vernalha Rocha Almeida ◽  
Daniel Silva dos Santos ◽  
Yury Oliveira Chaves ◽  
...  
Keyword(s):  
Platelet Activation ◽  
Opportunistic Infections ◽  
Tertiary Care ◽  
Enzyme Linked Immunosorbent Assay ◽  
People Living With Hiv ◽  
Care Hospital ◽  
Aids Patients ◽  
Distribution Width ◽  
Advanced Immunosuppression ◽  
Hiv Aids

Abstract Background The irregular use of antiretroviral therapy (ART) and late diagnosis still account for a large part of HIV-associated mortality in people living with HIV (PLHIV). Herein, we describe HIV-associated morbidity among hospitalised HIV/AIDS patients with advanced immunosuppression and assess the comorbidities, laboratory parameters, and immunological markers associated with mortality. Methods The cross-sectional study was conducted at the Fundação de Medicina Tropical Doutor Heitor Vieira Dourado (FMT-HVD) in Manaus, Brazil. In all, 83 participants aged between 12 and 70 years were enrolled by convenience within 72 h of their hospitalisation. Clinical and laboratory data were obtained from electronic medical records. We prospectively measured the cytokines Th1/Th2/Th17 and inflammatory cytokines IL-8, IL-1β, and IL-12 using cytometric bead array, and the soluble CD14 using in-house enzyme-linked immunosorbent assay. Results The HIV/AIDS inpatients presented a scenario of respiratory syndromes as the most prevalent comorbidity. Almost all patients had CD4 T counts below 350 cells/mL and the mortality rate was 20.5%. Pulmonary tuberculosis, neurotoxoplasmosis and oropharyngeal–esophageal candidiasis were the most prevalent opportunistic infections. TB and weight loss were more prevalent in HIV/AIDS inpatients who died. The Mann Whitney analysis showed that those who died had higher platelet distribution width (PDW) on admission, which is suggestive for platelet activation. The Poisson multivariate analysis showed the prevalence of TB, digestive syndrome and increases in IL-8 and lactate dehydrogenase (LDH) associated to death. Conclusions The advanced immunosuppression characterized by the opportunistic infections presented in these HIV/AIDS inpatients was the major factor of mortality. The role of platelet activation in worse outcomes of hospitalisation and the IL-8 associated with the context of advanced immunosuppression may be promising markers in the prediction of mortality in HIV/AIDS patients.

scholarly journals Opportunistic Infections and Associated Factors among HIV/AIDS Patients taking Ante-Retroviral Therapy at Selected Hospitals in Sidama Zone, Southern Ethiopia: A facility-based cross-sectional study

2019 ◽  
Author(s):  
Demelash Wachamo ◽  
Fisseha Bonja
Keyword(s):  
Associated Factors ◽  
Opportunistic Infections ◽  
Public Health Problem ◽  
Cross Sectional Study ◽  
High Morbidity ◽  
Major Public Health Problem ◽  
Sectional Study ◽  
Aids Patients ◽  
Cross Sectional ◽  
Hiv Aids

Abstract Background Opportunistic infections are late complications of HIV infection is the depletion of the immune system. It is a major public health problem and high morbidity AIDS patients die of AIDS-related infections in developing countries like Ethiopia. Identification of opportunistic infections (OIs) is important to develop a specific intervention. Therefore, this study aimed to assess the burden and associated factors of opportunistic infections.Method A facility-based cross-sectional study was conducted on 420 randomly selected HIV/AIDS patients taking anti-retroviral therapy. Data was collected from selected hospitals in Sidama Zone based on population proportion to size. Data was collected by a pre-tested questionnaire and a pre-tested checklist from the medical records of patients. Data entry and analyzed for descriptive and logistic regression models by SPSS v.23. The result declared as statistically significant at p < 0.05.Result The magnitude of opportunistic infections was 39.6%. Major identified OIs was oral candidacies 23.2%, recurrent bacterial pneumonia 21.5%, Herpes zoster 6.3%, and Pulmonary Tuberculosis 6.0%.The magnitude of opportunistic associated with; older age [AOR=2.69, 95% CI: 1.33-5.43], No formal education [AOR=3.12, 95% CI: 1.06-9.25], Low monthly income [AOR=2.27, 95%CI:1.35-3.83], initial CD4 count less than 200 cells/mm3 [AOR=1.91, 95% CI:1.05-3.46), WHO clinical stage II [AOR=2.43, 95% CI:1.34-4.42] and stage III and IV [AOR=4.27, 95% CI: 2.12-8.59], had no extra medicine additional to ART (prophylaxis) had [AOR= 5.91, 95% CI: 3.31-10.56], who interrupt ART medicines [AOR=2.03, 95% CI: 1.09- 3.80] and Khat chewing [AOR=5.48, 95% CI: 2.32-12.96] when compared to their counterparts.Conclusions The overall magnitude of opportunistic infections was high when compared with other studies. Health officials and clinicians need to give attention on the strengthening of the provision if ART with prophylaxis on early-stage and adhrerence, implementation of the TB/HIV collaboration activity, and early initiation of ART to reduce opportunistic infections.

scholarly journals PREVALENCE OF ADVERSE DRUG REACTIONS AMONG HIV/AIDS PATIENTS ON HAART IN UNIVERSITY OF MAIDUGURI TEACHING HOSPITAL (UMTH), NIGERIA: A FOUR-YEAR RETROSPECTIVE STUDY

2017 ◽  
Vol 2 (Suppl 2) ◽  
pp. A39.2-A39
Author(s):  
Peter Bassi ◽  
Wadzani Gashau ◽  
Klungel Olaf ◽  
Alexander Dodoo ◽  
Prosper Okonkwo ◽  
...  
Keyword(s):  
Retrospective Study ◽  
Adverse Drug Reactions ◽  
Teaching Hospital ◽  
Drug Reactions ◽  
Aids Patients ◽  
Hiv Aids

scholarly journals HIV/AIDS Patients’ Survival Rate between One Co-infection and More Than One Opportunistic Co-infection at Haji Adam Malik General Hospital Medan in 2015-2017

2021 ◽  
Vol 8 (12) ◽  
pp. 447-453
Author(s):  
Rizal Abdul Munaf ◽  
Tambar Kembaren ◽  
Restuti Hidayani S
Keyword(s):  
Statistical Analysis ◽  
Survival Rate ◽  
Opportunistic Infections ◽  
Demographic Data ◽  
Oral Candidiasis ◽  
Hiv Patients ◽  
Aids Patients ◽  
Keywords Hiv ◽  
The Difference ◽  
Hiv Aids

Background: AIDS is a collection of disease symptoms caused by HIV that damages the human immune system. Decreased immunity causes the patient to be very susceptible to various, often fatal, infectious diseases (opportunistic infections). Aim: To determine the difference in HIV/AIDS patients' survival rate between one co-infection and more than one opportunistic co-infection at Haji Adam Malik Hospital Medan in 2015-2017. Methods: This is a retrospective cohort analytic study using secondary data from medical records of HIV patients from January 2015-December 2017. The samples were 34 HIV/AIDS patients who met the inclusion and exclusion criteria, selected by consecutive technique sampling. Descriptive statistical analysis was used for demographic data. Kaplan Meier's statistical analysis was used for endurance or survival tests. The difference was considered statistically significant if p<0.05. Results: The most opportunistic infections found were diarrhea in 265 subjects (55.67%), followed by toxoplasmosis in 159 subjects (33.40%), oral candidiasis 141 subjects (29.62%), CMV 78 subjects (16.39%), pneumonia 63 subjects (13.24%), sepsis 62 subjects (13.03%), PCP 45 subjects (9.45%), hepatitis B 38 subjects (7.98%), chlamydia 24 subjects (5.04%), hepatitis C 14 subjects (2, 94%), Herpes zoster 11 subjects (2.31%), lymphadenopathy 4 subjects (0.84%), and the least common were NHL 1 subject (0.21%) and Penicilosis 1 subject (0.21%). Conclusion: The HIV patients’ survival rates are different based on the number of opportunistic infections. According to the order, the most common opportunistic infections were diarrhea, toxoplasmosis, and oral candidiasis. Keywords: HIV/AIDS, opportunistic infections, oral candidiasis, toxoplasmosis, diarrhea.

scholarly journals Adult HIV/AIDS Patients’ Level of Satisfaction on Pharmaceutical Service: Institutional Prospective Cross Sectional Study

2019 ◽  
Author(s):  
Adey Girmay ◽  
Zelalem Tilahun ◽  
Muluemebet Zinabu Akele ◽  
solomon Assefa Huluka
Keyword(s):  
Addis Ababa ◽  
Cross Sectional Study ◽  
Memorial Hospital ◽  
Sources Of Information ◽  
Sectional Study ◽  
Aids Patients ◽  
Cross Sectional ◽  
Pharmaceutical Service ◽  
Level Of Satisfaction ◽  
Hiv Aids

Abstract Objective : Patients are essential sources of information to assess the accessibility and effectiveness of pharmaceutical care. Patients’ perception and satisfaction on the care they received has direct influence on treatment adherence. This study was thus aimed to assess HIV/AIDS patients’ level of satisfaction on the pharmaceutical services provided in Zewditu Memorial Hospital, Addis Ababa, Ethiopia. An institution based cross sectional study was conducted from April 16, 2018 to May 16, 2018 in Zewditu Memorial Hospital. Result: Among the total 285 participants enrolled in the study, 172(60.4%) of them were females and the mean age of the participants was 42.5±9.8. The participants of this study received ART service for a mean duration of 7.3±3.5 years. In this study, 26.7%, 13.7%, 38.6%, 13% and 8.1% of the study participants rated the overall satisfaction to the ART pharmaceutical service as excellent, very good, good, fair, and poor, respectively. Participants who were provided information about drug-drug and drug-food interaction were 2.72 times more likely to be satisfied than those who weren’t provided (AOR=2.72, 95%CI : 1.13-6.54).

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