scholarly journals PATHOGENETIC APPROACH TO EARLY DIAGNOSIS OF MILD NEURO-ORTHOPEDIC PATHOLOGY IN CHILDREN

2020 ◽  
Vol 76 (4) ◽  
pp. 106-109
Author(s):  
M.E. Winderlich ◽  
◽  
N.B. Schekolova ◽  
Keyword(s):  
Differential Diagnosis ◽  
Early Diagnosis ◽  
Children And Adolescents ◽  
Research Methods ◽  
Musculoskeletal System ◽  
Spinal Deformity ◽  
Foot Placement ◽  
Pelvic Bones ◽  
Timely Diagnosis ◽  
Treatment And Prevention

216 children and adolescents from 3 months to 17 years with mild neuroorthopedic pathology – torticollis, abnormal foot placement, flat-valgus feet, posture disorders, scoliosis, shortening of the limb were examined. The etiological factors of Natal trauma and the pathogenesis of torticollis formation were determined with confirmation by instrumental research methods. During the growth of the child, there is a progression of neuroorthopedic pathology in the form of scoliotic spinal deformity with a misalignment of the pelvic bones due to an asymmetric flat-valgus installation of the feet. The program for differential diagnosis and prevention of mild neuroorthopedic disorders was developed depending on the age of children. It is shown, that the leading link in the pathogenesis of neuroorthopedic pathology is natal trauma. Timely diagnosis, treatment and prevention of disorders of the musculoskeletal system will prevent the formation of pathology in various age periods.

Strontium 87m Scanning of Pelvic Bones

1968 ◽  
Vol 07 (01) ◽  
pp. 28-36 ◽  
Author(s):  
Władysław Jasiński ◽  
Janina Malinowska ◽  
Henryk Mackiewicz ◽  
Henryk Siwicki ◽  
Krystyna Lukawska
Keyword(s):  
Body Weight ◽  
Differential Diagnosis ◽  
Early Diagnosis ◽  
Femoral Neck ◽  
Early Period ◽  
Early Recurrence ◽  
Physical Activities ◽  
External Irradiation ◽  
Pelvic Bones ◽  
Strontium 87M

SummaryThe purpose of this investigation was to study the accumulation of 87mSr in the proximal parts of the femoral bones of patients treated previously by external irradiation due to cancer of the uterine cervix. It was assumed that this method may be used in the future for the early diagnosis of postirradiation changes of bone (osteoradionecrosis).The incidence of postirradiation changes of the femoral neck among 5735 patients treated between 1950 and 1961 at the Department of Gynaecology of the Institute, was 0.8%. In the early period of postirradiation changes the patients complain only of pain and limitation of physical activities. If radiological and gynaecological findings were negative, the differential diagnosis between early recurrence and early osteoradionecrosis became impossible.49 selected patients were scanned after intravenous injection of 10—115 μCi of 87mSr per kg of body weight (0.5 up to 6.0 mCi). Illustrative cases of normal pelvic bones as well as postirradiation changes are presented and discussed. The authors conclude that the findings justify further systematic studies on the morphology of accumulation of 87mSr in the bones.

CLINICAL CASE: MICROSCOPIC POLYANGIITIS AS ONE OF THE MAIN VARIANTS OF PULMONARY-RENAL SYNDROME

Vestnik ◽  
2021 ◽  
pp. 345-349
Author(s):  
М.А. Жанузаков ◽  
М.К. Бапаева ◽  
А.Ж. Шурина ◽  
Э.М. Утежанов
Keyword(s):  
Differential Diagnosis ◽  
Early Diagnosis ◽  
Research Methods ◽  
Clinical Case ◽  
Microscopic Polyangiitis ◽  
Clinical Manifestations ◽  
Additional Research ◽  
Treatment Goal ◽  
Adequate Treatment ◽  
Pulmonary Renal Syndrome

Клинические проявления микроскопического полиангиита многообразны, что затрудняет своевременную диагностику и соответственно адекватное лечение. Цель: привлечь внимание терапевтов, пульмонологов, нефрологов к своевременному выявлению легочно-почечного синдрома и установлению его нозологической основы, в частности микроскопического полиангиита на примере клинического случая. Материалы и методы: проведены обследование пациента с микроскопическим полиангиитом и дифференциальная диагностика в рамках легочно-почечного синдрома. Результаты: на основании анамнеза заболевания, результатов клинического и дополнительных методов исследования пациента, установлен диагноз микроскопического полиангиита. Выводы: для ранней диагностики микроскопического полиангиита необходима настороженность при возникновении легочно-почечного синдрома в виде сочетания гломерулонефрита и геморрагического альвеолита на фоне сосудистой пурпуры. Clinical manifestations of microscopic polyangiitis are diverse, which complicates timely diagnosis and, accordingly, adequate treatment. Goal: to draw the attention of therapists, pulmonologists, nephrologists to the timely detection of pulmonary-renal syndrome and the establishment of its nosological basis, in particular microscopic polyangiitis by the example of a clinical case. Materials and methods: an examination of a patient with microscopic polyangiitis and differential diagnosis within the framework of pulmonary-renal syndrome were carried out. Results: based on the anamnesis of the disease, the results of clinical and additional research methods of the patient, the diagnosis of microscopic polyangiitis was established. Conclusions: for early diagnosis of microscopic polyangiitis, alertness is necessary in the event of pulmonary-renal syndrome in the form of a combination of glomerulonephritis and hemorrhagic alveolitis against the background of vascular purpura.

scholarly journals Lung Injury Induced by Antitumor Drugs: Diagnosis, Features of the Clinical Course, Risk Factors, Differential Diagnosis, Treatment, and Prevention. Part 1

2021 ◽  
Vol 99 (7) ◽  
pp. 55-62
Author(s):  
N. V. Orlovа ◽  
O. D. Ostroumovа ◽  
E. V. Shikh ◽  
S. V. Smerdin ◽  
E. V. Rebrovа ◽  
...  
Keyword(s):  
Risk Factors ◽  
Differential Diagnosis ◽  
Early Diagnosis ◽  
Lung Injury ◽  
Tobacco Smoking ◽  
Clinical Course ◽  
Antitumor Drugs ◽  
Drug Induced ◽  
Duration Of Therapy ◽  
Treatment And Prevention

57 publications on pneumotoxicity of antitumor drugs were analyzed. It was found that the development of pneumotoxic effects could be influenced by risk factors such as gender, age, tobacco smoking, comorbidities, and duration of therapy. Symptoms of lung injury induced by antitumor drugs are nonspecific thus it is difficult to diagnose them promptly. For prevention, early diagnosis and timely management of drug-induced lung injury during antineoplastic therapy, it is necessary to raise awareness of such a condition in practitioners of different specialties, primarily general practitioners, pulmonologists, phthisiologists, and oncologists.

scholarly journals FM Combined With NIHSS Score Contributes to Early AIS Diagnosis and Differential Diagnosis of Cardiogenic and Non-Cardiogenic AIS

2021 ◽  
Vol 27 ◽  
pp. 107602962110001
Author(s):  
Dan Wu ◽  
Yong’e Liu
Keyword(s):  
Differential Diagnosis ◽  
Early Diagnosis ◽  
Diagnostic Efficacy ◽  
Stroke Treatment ◽  
Nihss Score ◽  
Stroke Group ◽  
Diagnosis And Classification ◽  
Toast Classification ◽  
Thrombotic Diseases ◽  
D Dimer

A growing researchers have suggested that fibrin monomer (FM) plays an important role in early diagnosis of thrombotic diseases. We explored the application of FM in the diagnosis and classification of acute ischemic stroke (AIS). The differences in FM, D-dimer, and NIHSS scores between different TOAST (Trial of ORG 10172 in Acute Stroke Treatment) types were analyzed with one-way ANOVA; the correlation between FM, D-dimer and NIHSS score in patients with different TOAST classification was analyzed by Pearson linear correlation. The ROC curve was utilized to analyze the diagnostic performance. 1. FM was more effective in diagnosing patients with AIS than D-dimer. 2. The FM level in cardiogenic AIS was significantly different from that in non-cardiogenic patients ( P < 0.05); the NIHSS score in cardiogenic stroke was significantly higher than in atherosclerotic and unexplained stroke group. Whereas, no statistical difference was observed in the D-dimer level between these groups ( P > 0.05). 3. The correlation between FM and NIHSS scores in the cardiogenic (r = 0.3832) and atherosclerotic (r = 0.3144) groups was statistically significant. 4. FM exhibited the highest diagnostic efficacy for cardiogenic AIS; furthermore, FM combined with the NIHSS score was more conducive to the differential diagnosis of cardiogenic and non-cardiogenic AIS. FM detection contributes to the early diagnosis of AIS, and is important for the differential diagnosis of different TOAST types of AIS. Moreover, FM combined with the NIHSS score is valuable in the differential diagnosis of cardiogenic and non-cardiogenic AIS.

Concrescence of the cervical vertebrae and neurological complications

2021 ◽  
pp. 195-201
Author(s):  
Sabiyat Abdulaevna Yakhyaeva ◽  
Naida Isagadzhievna Garabova ◽  
Madina Garunovna Burzhunova
Keyword(s):  
Cervical Spine ◽  
Clinical Practice ◽  
Research Methods ◽  
Neurological Disorders ◽  
Cervical Vertebrae ◽  
Clinical Manifestations ◽  
Neurological Complications ◽  
Timely Diagnosis ◽  
Number Of Patients ◽  
Genetically Determined

In clinical practice, a sufficiently large number of patients complain of neurological disorders caused by osteochondrosis of the cervical spine. Despite this, in some cases, the development and progression of this symptomatology may be due to an anomaly in the structure of the cervical spine (Klippel-Feil syndrome), which is genetically determined. Timely diagnosis of this pathology with the implementation of complex research methods allows you to develop individual tactics for each individual patient, taking into account the severity of clinical manifestations to slow the progression of complications.

CHEST PAIN AND DEPRESSION

PEDIATRICS ◽  
1982 ◽  
Vol 70 (4) ◽  
pp. 575-575
Author(s):  
R. J. Haggerty
Keyword(s):  
Major Depressive Disorder ◽  
Differential Diagnosis ◽  
Chest Pain ◽  
Depressive Disorder ◽  
Children And Adolescents ◽  
Pediatric Cardiology ◽  
Cardiovascular Disorders ◽  
Major Depressive ◽  
Cardiology Department ◽  
Depressed Group

The study reports on 100 children and adolescents evaluated in a pediatric cardiology department. The results state that 13% of the population met the criteria for Major Depressive Disorder based on DSM III. There were four patients who were referred because of chest pain. All of them were found to be free from cardiovascular disorders, but all were found to be in the depressed group. The authors emphasize the importance of chest pain in differential diagnosis of childhood depression.

Cardiomyopathies in the clinical picture of emergency cardiology

1998 ◽  
Vol 79 (1) ◽  
pp. 23-27
Author(s):  
I. A. Latfullin ◽  
O. V. Bogoyavlenskaya
Keyword(s):  
Differential Diagnosis ◽  
Early Diagnosis ◽  
Transesophageal Echocardiography ◽  
Clinical Picture

The peculiarities of the clinical picture and diagnosis of uncoronarogenic lesions of the myocardium in a period of 5 years are studied. The differential diagnosis of cardiomyopathies and myocardial dystrophies is performed, emphasizing the informativity of contrast and transesophageal echocardiography. Registration of electrocardiographic and echocardiographic data allows to choose among patients the persons demanding the expanding cardiologic examination that provides early diagnosis of latent forms of cardiomyopathies.

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