scholarly journals Effect of Soyflour (Glycine max L.) Hepatoprotector Activity on Liver MDA Level in Male Wistar Rat Induced by Diazinon

2018 ◽  
Vol 4 (1) ◽  
pp. 1
Author(s):  
Sofi Aliyatul Himah ◽  
Desie Dwi Wisudanti ◽  
Heni Fatmawati
Keyword(s):  
Lipid Peroxidation ◽  
Glycine Max ◽  
Pearson Correlation ◽  
Wistar Rat ◽  
Soy Flour ◽  
Strong Negative Correlation ◽  
Level Increase ◽  
Glycine Max L ◽  
Post Hoc ◽  
One Way Anova

Diazinon is metabolized in liver becomes diazoxon, an active metabolite form that can cause free radical raisingthat leads to lipid peroxidation. The result of lipid peroxidation is MDA. Soyflour has higher isoflavones than theother processed food of Glycine max L.This isoflavones donate its electron and hydrogen atom in lipidperoxidation so it can block the lipid peroxidation. The aim of this experiment is to investigate the effect of soyflour on MDA hepar level increase of male wistar rat induced by diazinon. The sample are divided into 5 groupswhich are Kn, K(-) group induced by diazinon 40mg/kgBW, K1, K2, K3 group given with soy flour 10%, 15%, and20% orally, then induced by diazinon 40 mg/kgBW. MDA liver measured on the day 34th with MDA-TBAmethode which has pink colour and measured by spectrofotometer. Average of liver MDA levels is Kn 6,35μg/mL; K(-) 9,23 μg/mL; K1 8,85 μg/mL; K2 7,88 μg/mL; K3 7,04 μg/mL. One way ANOVA and Post hoc LSDshowed significantly different (p<0,05). Pearson correlation showed strong negative correlation. Keywords: Diazinon, Diazoxon, MDA, Soyflour, Glycine max L., antioxidant

scholarly journals Serum Interleukin-2 (IL-2) Levels in Untreated and Treated in Batak Tribe Patients with Schizophrenia

2021 ◽  
Vol 4 (1) ◽  
pp. 1449-1460
Author(s):  
Julius Martin Siagian ◽  
Elmeida Effendy ◽  
Mustafa M. Amin
Keyword(s):  
General Hospital ◽  
Pearson Correlation ◽  
Interleukin 2 ◽  
Cross Sectional ◽  
Welch Test ◽  
Pearson Correlation Test ◽  
Healthy Control ◽  
The Difference ◽  
Post Hoc ◽  
One Way Anova

To find out the difference of serum IL-2 levels between untreated and treated in the Batak tribe patients with schizophrenia and healthy control and also to find out the association between serum IL-2 levels with PANSS score in the Batak tribe patients with schizophrenia. This study was cross-sectional approach using a one-way ANOVA welch test and to find a correlation between serum IL-2 levels with PANSS score in the Batak tribe patients with schizophrenia which is conducted in Prof. Dr. M. Ildrem Psychiatric Hospital Medan and Dr. Pirngadi General Hospital Medan from September 2019-November 2019. Subjects of untreated were 55 subjects and treated in the Batak tribe patients with schizophrenia were 55 subjects and healthy control were 55 subjects. There were significant differences between these three groups using post hoc Games-Howell test on the value of p<0.001 and also been found there was a significant correlation between serum IL-2 levels with PANSS score in the Batak tribe patients with schizophrenia using the Pearson correlation test (r=0.599, p=0.001 and r=0.501, p=0.001). It was founded that there were significant differences between serum IL-2 levels in three groups and also founded there was a significant correlation between serum IL-2 levels with PANSS score in the Batak tribe patients with schizophrenia. 

scholarly journals Influence of Different Enamel Shades and Thickness on Chroma and Value of Dentin Vita Shade: An in vitro Comparative Assessment Study

2015 ◽  
Vol 16 (4) ◽  
pp. 304-309 ◽  
Author(s):  
N Meena ◽  
Deepak Mehta ◽  
Noor Saira Wajid Najma Hajira ◽  
P Ashwini ◽  
HL Usha
Keyword(s):  
Composite Resin ◽  
Pearson Correlation ◽  
Correlation Coefficients ◽  
Comparative Assessment ◽  
Optimum Thickness ◽  
Assessment Study ◽  
Natural Teeth ◽  
Post Hoc ◽  
One Way Anova

ABSTRACT Background The aim of the present study is to determine the influence of different enamel shades of various thickness on chroma and value of vita shade of dentin. Materials and methods Three enamel composite resin shades (Enamel white, grey and neutral) and one dentin shade (A2) from Amelogen Plus (Ultradent) was used. Ninety Enamel disk specimens of 0.5, 0.75 and 1 mm thickness and 10 mm in diameter for each shade and 90 dentin disk specimens of 2 mm in thickness and 10 mm in diameter was used for the study. The spectrophotometric values of the dentin shade with and without enamel specimens were recorded and the values were converted to CIE L*a*b values. Results Statistical analysis was done using Pearson correlation coefficients to verify the effect of thickness on Chroma and value, and the significance was evaluated by one-way ANOVA and Tukey post hoc test. Two way ANOVA and Tukey post hoc was done to verify the variation within the groups. Results revealed a significant positive correlation between thickness and chroma and a negative correlation between thickness and value. There was a statistically significant variation in between the groups. Conclusion All groups produced a significant increase in chroma with increase in thickness of enamel shade upto a thickness of 0.75 mm after which the behavior of each shade was erratic. Hence, the optimum thickness would be 0.75 mm. All groups produced a significant decrease in value with increase in thickness of enamel shade. Enamel white produced the greatest reduction in value, enamel neutral the least and enamel grey demonstrated an intermediate result. Clinical significance There is a need to have a knowledge of the effect on chroma and value when dentin is layered with different enamel shades, it is also important to understand the effect of these enamel shades at different thicknesses to better control the color and reproduce esthetic simulating natural teeth. How to cite this article Hajira NSWN, Mehta D, Ashwini P, Meena N, Usha HL. Influence of Different Enamel Shades and Thickness on Chroma and Value of Dentin Vita Shade: An in vitro Comparative Assessment Study. J Contemp Dent Pract 2015;16(4):304-309.

scholarly journals Peroxidase and lipid peroxidation of soybean roots in response to p-coumaric and p-hydroxybenzoic acids

2003 ◽  
Vol 46 (2) ◽  
pp. 193-198 ◽  
Author(s):  
Patrícia Minatovicz F. Doblinski ◽  
Maria de Lourdes L. Ferrarese ◽  
Domitila A. Huber ◽  
Carlos Alberto Scapim ◽  
Alessandro de Lucca e Braccini ◽  
...  
Keyword(s):  
Lipid Peroxidation ◽  
Cell Wall ◽  
Glycine Max ◽  
Root Growth ◽  
Root Length ◽  
Dry Weight ◽  
Fresh Weight ◽  
Glycine Max L ◽  
Hydroxybenzoic Acids ◽  
Soybean Roots

The scope of the present study was to investigate how the p-coumaric (p-CA) and p-hydroxybenzoic (p-HD) acids affect the peroxidase (POD, EC 1.11.1.7) activity, the lipid peroxidation (LP) and the root growth of soybean (Glycine max (L.) Merr.). Three-day-old seedlings were cultivated in nutrient solution containing p-CA or p-HD (0.1 to 1 mM) for 48 h. After uptake, both compounds (at 0.5 and 1 mM) decreased root length (RL), fresh weight (FW) and dry weight (DW) while increased soluble POD activity, cell wall (CW)-bound POD activity (with 1 mM p-CA and 0.5 mM p-HD) and LP.

Factors That Affect Age of Identification of Children With an Autism Spectrum Disorder

2016 ◽  
Vol 39 (1) ◽  
pp. 18-32 ◽  
Author(s):  
Chana R. Adelman ◽  
Thomas Kubiszyn
Keyword(s):  
Autism Spectrum Disorder ◽  
Pearson Correlation ◽  
Significant Negative Correlation ◽  
The United States ◽  
Autism Spectrum ◽  
Spectrum Disorder ◽  
Age Of Diagnosis ◽  
The Mean ◽  
Post Hoc ◽  
One Way Anova

This study explored factors associated with age of identification of autism spectrum disorder (ASD). Results of a one-way ANOVA indicated differences in age of diagnosis among the four regions in the United States, F(3, 650) = 7.618, p = .01. Tukey’s post hoc comparisons of the groups indicated that the mean age of diagnosis in the Midwest ( M = 38.9 months or 3 years, 3 months) was significantly later than in the Northeast ( M = 32.75 months or 2 years, 9 months, p = .000) and South ( M = 33.26 months or 2 years, 9 months, p = .000). Results of a Pearson correlation indicated a significant negative correlation ( r = −.409, n = 654, p = .000) between date of birth and age of diagnosis, with more recent birthdays associated with lower age of diagnosis. Regression results were statistically significant, F(25, 620) = 7.549, p < .001, R2 = .233, with some factors predicting earlier age of diagnosis and some factors predicting later diagnosis.

scholarly journals Biochemical Phenotyping of Soybean [Glycine max (L.) Merill] Genotypes to Establish the Role of Lipid Peroxidation and Antioxidant Enzymes in Seed Longevity

2013 ◽  
Vol 2 (2) ◽  
pp. 119-126 ◽  
Author(s):  
Jagadish Hosamani ◽  
M. Dadlani ◽  
I. M. Santha ◽  
M. B. Arun Kumar ◽  
Sherry Rachel Jacob
Keyword(s):  
Lipid Peroxidation ◽  
Antioxidant Enzymes ◽  
Glycine Max ◽  
Seed Longevity ◽  
Glycine Max L

scholarly journals Nephroprotective effect of soy (Glycine Max (L.) Merr.) flour against diazinon-induced renal toxicity in rats

2020 ◽  
Vol 39 (3) ◽  
pp. 192
Author(s):  
Desie Dwi Wisudanti ◽  
Rena Normasari ◽  
Firman Herdiyana
Keyword(s):  
Glycine Max ◽  
Wistar Rats ◽  
Negative Control Group ◽  
Negative Control ◽  
Soy Flour ◽  
Control Group ◽  
Treatment Groups ◽  
Male Wistar Rats ◽  
Glycine Max L ◽  
Nephroprotective Effect

<strong>Background</strong><br />Diazinon is a widely used pesticide to eradicate agricultural pests globally with the potential to cause harmful effects on humans by generating free radicals and depleting endogenous antioxidants. Soy flour possesses high antioxidant effect. This study evaluated the nephroprotective effect of soy flour  on diazinon-induced nephrotoxicity in rats. <br /><br /><strong>Methods</strong><br />An experimental laboratory study was carried out involving 30 male Wistar rats were randomly divided into five groups of 6 rats. The normal control (Kn) and the negative control (K-) groups <em>received</em> normal saline, the treatment groups (K1, K2, K3) received 10%, 15%, and 20% soy flour in distilled water, respectively, on day 1 to day 28. Subsequently, for five days, all groups received diazinon 40 mg/kg, except for the normal control group. Blood urea nitrogen (BUN) and creatinine levels were measured at the end of the study. The Kruskal Wallis test with the post hoc Mann Whitney U test were used to analyze the data. <br /><br /><strong>Results</strong><br />Blood urea nitrogen and creatinine levels were lower in all treatment groups (K1, K2, K3) compared to the negative control group (K-), while the K3 level was the lowest (24.28 ± 1.56 mg/dL and 0.93 ± 0.14 mg/dL).  There was a significant decrease in BUN and creatinine levels in the experimental rats of the 15% and 20% soy flour groups (K2, K3) compared to the negative control group (K-).<br /><br /><strong>Conclusion</strong><br />Administration of soy flour (Glycine max (L.) Merr.) had a nephroprotective effect in preventing increases in BUN and creatinine levels of diazinon-induced nephrotoxic male Wistar rats.

scholarly journals THE EFFECT OF RAMBUTAN (Nephelium lappaceum L.) PEEL EXTRACT ON LIPID PEROXIDATION IN LIVER OF OBESE RATS

2015 ◽  
Vol 2 (1) ◽  
pp. 326 ◽  
Author(s):  
Arie Setyawati ◽  
Arifia Kusuma Dewi ◽  
Mochammad Fitri Atho’illah ◽  
Umie Lestari ◽  
Sri Rahayu Lestari
Keyword(s):  
Oxidative Stress ◽  
Lipid Peroxidation ◽  
Wistar Rat ◽  
Randomized Design ◽  
Nephelium Lappaceum ◽  
Obese Rats ◽  
High Oxidative Stress ◽  
Per Oral ◽  
One Way Anova ◽  
Peel Extract

<p>Lipid accumulation is main cause of obesity which then may cause liver damage due to a high oxidative stress. The oxidative stress in cell can cause lipid peroxidation. This process can be prevented by giving the external antioxidants. Previous study reported that rambutan peel extract reduced mice body weight and several adipogenesis parameters in visceral lipid. The objective of this research was to study the effect of rambutan peel extract on lipid peroxidation and accumulation in the liver of obese rats. The research was arranged in a complete randomized design (CRD). The experimental animals used were male Wistar rat aged 13 weeks weighed 310-340 gram which grouped into 5 groups; each group was given 15mg/kgbw, 30mg/kgbw, 60mg/kgbw, distilled water (C+), or nothing (C-). The extract was given per oral once every two days. The observed parameter are MDA levels and PPAR. expression. At week 12th the animals were dissected, the liver were isolated and tested for Malondialdehyde (MDA) level using TBA and PPARã expression using Immunohistochemistry. Data was analyzed using One Way ANOVA. The results showed that rambutan peel extract in 15 and 30mg/kgbw significantly decrease MDA levels and not significantly down regulate the expression of PPAR..</p><p><strong>Keywords</strong>: rambutan peel extract, lipid peroxidation, Malondialdehyde, PPAR..</p>

Prevalence of the pit and antipit in the genus Glycine

1987 ◽  
Vol 45 ◽  
pp. 986-987
Author(s):  
R. W. Yaklich ◽  
E. L. Vigil ◽  
W. P. Wergin
Keyword(s):  
Amino Acids ◽  
Endoplasmic Reticulum ◽  
Glycine Max ◽  
Seed Coat ◽  
Cell Types ◽  
Abaxial Surface ◽  
Legume Seed ◽  
Initial Report ◽  
Cone Cells ◽  
Glycine Max L

The legume seed coat is the site of sucrose unloading and the metabolism of imported ureides and synthesis of amino acids for the developing embryo. The cell types directly responsible for these functions in the seed coat are not known. We recently described a convex layer of tissue on the inside surface of the soybean (Glycine max L. Merr.) seed coat that was termed “antipit” because it was in direct opposition to the concave pit on the abaxial surface of the cotyledon. Cone cells of the antipit contained numerous hypertrophied Golgi apparatus and laminated rough endoplasmic reticulum common to actively secreting cells. The initial report by Dzikowski (1936) described the morphology of the pit and antipit in G. max and found these structures in only 68 of the 169 seed accessions examined.

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