COMPLICATIONS AND OUTCOMES OF PREGNANCY IN GESTATIONAL DIABETES MELLITUS

The aim of the study was to analyze the complications and examine the outcomes of pregnancy in women with compensated gestational diabetes mellitus.We studied outcomes and complications of pregnancy in 50 pregnant women with gestational diabetes mellitus, the effects of gestational diabetes on the fetus.The average age of pregnant women was (33.7 ± 5.7) years. The incidence of gestoses and placental insufficiency in compensated gestational diabetes mellitus was 84%, polyhydramnios – 36%, the fetus fetopathy – 48% of cases. Births in period occurred in 96% of cases, the frequency of fetal malformations consistent with population-based indicators.Gestational diabetes mellitus affects the development of gestosis and fetoplacental insufficiency, even when the compensation of carbohydrate metabolism after the diagnosis of gestational diabetes mellitus.

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Interactions between general and central obesity in predicting gestational diabetes mellitus in Chinese pregnant women: A prospective population-based study in Tianjin, China

Journal of Diabetes ◽

10.1111/1753-0407.12558 ◽

2017 ◽

Vol 10 (1) ◽

pp. 59-67 ◽

Cited By ~ 5

Author(s):

Qian Han ◽

Ping Shao ◽

Junhong Leng ◽

Cuiping Zhang ◽

Wei Li ◽

...

Keyword(s):

Diabetes Mellitus ◽

Gestational Diabetes ◽

Gestational Diabetes Mellitus ◽

Pregnant Women ◽

Central Obesity ◽

Population Based ◽

Population Based Study

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Risk factors of gestational diabetes mellitus using results of a prospective population-based study in Iranian pregnant women

Diabetes & Metabolic Syndrome Clinical Research & Reviews ◽

10.1016/j.dsx.2018.04.014 ◽

2018 ◽

Vol 12 (5) ◽

pp. 721-725 ◽

Cited By ~ 6

Author(s):

Ferdos Zaman ◽

Sedigheh Nouhjah ◽

Hajieh Shahbazian ◽

Nahid Shahbazian ◽

Seyed Mahmoud Latifi ◽

...

Keyword(s):

Diabetes Mellitus ◽

Risk Factors ◽

Gestational Diabetes ◽

Gestational Diabetes Mellitus ◽

Pregnant Women ◽

Population Based ◽

Population Based Study

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The associations of incretin hormone concentration with gestational diabetes mellitus

Diabetes Mellitus ◽

10.14341/dm2004134-37 ◽

2016 ◽

Vol 19 (2) ◽

pp. 150-157 ◽

Cited By ~ 2

Author(s):

Tatiana V. Saprina ◽

Ekaterina S. Timokhina ◽

Olga K. Goncharevich ◽

Svetlana V. Budeeva ◽

Tatiana S. Prokhorenko ◽

...

Keyword(s):

Diabetes Mellitus ◽

Gestational Diabetes ◽

Gestational Diabetes Mellitus ◽

Pregnant Women ◽

Carbohydrate Metabolism ◽

Hormone Secretion ◽

Control Group ◽

Oral Glucose ◽

Incretin Hormone ◽

Metabolism Disorder

Background: Enteropancreatic hormonal system disorder is a possible reason for β-cell dysfunction and carbohydrate metabolism disorder among pregnant women. However, no information is available about the state of enteroinsulin hormones [glucagon, glucose-dependent insulinotropic peptide (GIP), glucagon-like peptide1 (GLP-1) and GLP-2] during pregnancy. The role of enteroinsulin hormones in the development of carbohydrate metabolism disorder during pregnancy is poorly understood. Aim: To quantify and compare incretin hormone secretion in groups of pregnant women with and without gestational diabetes mellitus (GDM). Materials and methods: The study included 80 patients, 50 of whom had GDM, and the control group consisted of 30 pregnant women without GDM. All patients underwent an oral glucose tolerance test; glycated haemoglobin (HbA1c) estimation; ferritin, transferrin, basal and postprandial glucagon estimation; GLP-1 and GLP-2 estimation. Results: Basal glucagon and GLP-1 levels were significantly higher (p 0. 05) in the group of women with GDM than in the control group. The most significant differences in GLP-1, basal and postprandial glucagon levels were observed during the first trimester of pregnancy. Conclusion: High GLP-1 levels in the group of women with GDM may reflect a state of ‘incretin resistance’, which is similar to hyperinsulinemia in the early stages of type 2 diabetes mellitus.

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Hemostasis in pregnant women with gestational diabetes mellitus

Journal of obstetrics and women s diseases ◽

10.17816/jowd622101-109 ◽

2013 ◽

Vol 62 (2) ◽

pp. 101-109

Author(s):

Roman Viktorovich Kapustin ◽

Olga Nikolayevna Arzhanova ◽

Tatyana Nikolayevna Shlyakhtenko ◽

Tatyana Ivanovna Oparina ◽

Yevgeniy Konstantinovich Komarov

Keyword(s):

Diabetes Mellitus ◽

Venous Thromboembolism ◽

Gestational Diabetes ◽

Gestational Diabetes Mellitus ◽

Pregnant Women ◽

Carbohydrate Metabolism ◽

Important Predictor ◽

Hemostatic Disorders ◽

Increased Activity ◽

In Pregnancy

Been analyzed and studied the characteristics of hemostasis in pregnant women with gestational diabetes mellitus. Found that for women with disorders of carbohydrate metabolism characte-rized by increased activity of procoagulant, vascular-platelet hemostasis, and decreased activity of fibrinolityc system. It is shown that the violations of the haemostatic system is directly dependent on the degree of compensation of carbohydrate metabolism and require adequate correction of glycemia. Thus, GDM is an important predictor of hemostatic disorders and possible venous thromboembolism in pregnancy.

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Peculiarities of carbohydrate metabolism in pregnant women with bronchial asthma

Journal of obstetrics and women s diseases ◽

10.17816/jowd67556-61 ◽

2018 ◽

Vol 67 (5) ◽

pp. 56-61

Author(s):

Elena A. Shapovalova ◽

Olga V. Lavrova ◽

Anna V. Paliychuk

Keyword(s):

Diabetes Mellitus ◽

General Population ◽

Gestational Diabetes ◽

Gestational Diabetes Mellitus ◽

Pregnant Women ◽

Carbohydrate Metabolism ◽

Bronchial Asthma ◽

Effect Of Therapy ◽

Long Acting ◽

Inhaled Glucocorticoids

Hypothesis/aims of study. The aim of this study was to assess the effect of therapy with inhaled glucocorticoids on the course of pregnancy, childbirth, and growth-weight parameters of newborns from mothers with asthma of varying severity. Study design, materials, and methods. 725 women aged 17 to 43 years with bronchial asthma were examined. In the group of patients with bronchial asthma, 352 patients (48.5%) received glucocorticoids or glucocorticoids + β2-long-acting agonists. Carbohydrate metabolism disorders were found in 45 (6.2%) examined pregnant women, among them 21 women (46.7%) received inhaled glucocorticoids. Results. The frequency of detection of gestational diabetes mellitus in pregnant women with bronchial asthma, as well as growth-weight parameters of newborns do not differ from the general population.

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GESTATIONAL DIABETES MELLITUS

V F Snegirev Archives of Obstetrics and Gynecology ◽

10.18821/2313-8726-2017-4-2-61-67 ◽

2017 ◽

Vol 4 (2) ◽

pp. 61-67

Author(s):

N. G Blokhin ◽

D. M Shevchenko

Keyword(s):

Diabetes Mellitus ◽

Gestational Diabetes ◽

Gestational Diabetes Mellitus ◽

Pregnant Women ◽

Carbohydrate Metabolism ◽

Glucose Concentration ◽

Reproductive Age ◽

Modern World ◽

Modern Methods

In the modern world, gestational diabetes mellitus (HDM) is a common disorder of carbohydrate metabolism in pregnant women, that indicates to the undoubted relevance of this problem in women of the reproductive age. High values of glucose concentration adversely affect not only the pregnant’s body, but also the fetus, that confirms the importance of timely diagnosis of GDM. In the article there was executed analysis both of modern literature data, testifying the role of this pathology in the occurrence of complications during pregnancy, and modern methods of diagnostics and treatment.

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