scholarly journals Prevalence of Intestinal Opportunistic Parasites Infections among HIV Positive Children in the University Hospital Center Yalgado Ouédroago of Ouagadougou, Burkina Faso

Author(s):  
Traoré Roukiatou Zongo Cheikna ◽  
Zongo Oumarou Ouédraogo Ganamé Abasse ◽  
Zida Adama Yonaba Caroline ◽  
Traoré Yves Savadogo Aly

In sub-Saharan Africa, Gastrointestinal parasites infections are widespread, particularly among immune deficient individuals. Prevalence of these infections varies from locality to other due to many factors. The present cross-sectional study aimed to assess the prevalence of intestinal parasites among HIV-positive children in the paediatric clinic at the University Hospital Yalgado Ouedraogo of Ouagadougou. A cross-sectional study was conducted in the University hospital of Ouagadougou from July to November 2015. Ninety-three (93) freshly issued stool samples were collected in HIV-positive children less than 15 years old. Stool samples were analysed for the presence of various intestinal parasites using direct microscopy, formol-ether concentration method, modified Ziehl Neelsen stain and Weber trichrome stain. The study included 93 HIV positive children. The prevalence of intestinal parasitic infection was 24.73% (23/93). The most detected parasites were Entamoeba coli (52.17% of total detected parasites), Trichomonas intestinalis (21.73%), Giardia intestinalis (8.65%), Entamoeba histolytica (4.34%). Patients with multi-infection (2 or 3 parasites) have been detected. The participants, 97.5% (89/93) were on cotrimoxazole prophylaxis and 81.76% (76/93) were on ARV therapy. Despite the medical care given to the HIV-infected children, the prevalence of opportunistic intestinal is high at the University hospital Yalgado Ouédraogo (CHU-YO)and deserves special attention.

Author(s):  
Lorena S. Miranda ◽  
Ana L. Cavalcante ◽  
Rafael M. Pinheiro ◽  
Dayani Galato ◽  
Emília V. Silva

Introduction: The reconciliation of medications is an important process that impacts on patient safety during the level of care transition, a moment with high discrepancy rates that can lead to adverse reactions. Objective: To analyze the results of medication reconciliation in order to identify discrepancies between the medical prescription and the medications previously used by the patient. Method: A descriptive, cross-sectional study was conducted between May and November 2017 (until the second fortnight of the month), with patients admitted to the cardiology department of the University Hospital of Brasília. Data was collected through interviews with patients, relatives and/or caregivers, and through consultation of the medical records. The reconciliation of medications was performed daily, from Monday to Friday, within 48 hours of the patient’s admission to the unit, through a medication reconciliation form prepared by the author. Results: 90 patients were included in the study and a total of 297 discrepancies were found, 267 (90%) being intentional and 30 (10%), unintentional. Among the unintentional discrepancies, the most frequent was omission of medication in use by the patient (56%). Of the intentional discrepancies, the dosage modifications were more common in 45% of the cases. Conclusion: The reconciliation of medications was a crucial clinical service for the identification and resolution of unintentional discrepancies between previously used medications and hospital medical prescription.


2021 ◽  
Vol 77 (1) ◽  
Author(s):  
Oyéné Kossi ◽  
Mendinatou Agbetou ◽  
Sènadé I. Noukpo ◽  
Lisa T. Triccas ◽  
Daniel-Eude Dossou-Yovo ◽  
...  

Background: Balance impairment is the predominant risk factor for falls in stroke survivors. A fear of falling after stroke can contribute to sedentary lifestyles, increased disability and risk of recurrence, leading to poor quality of life.Objective: To determine the frequency and factors associated with balance impairments amongst stroke survivors at the University Hospital of Parakou.Method: This cross-sectional study included adult stroke survivors. Stroke survivors after discharge were enrolled at the University Hospital of Parakou between 01 January 2020 and 30 September 2020. Balance impairments were measured by using the Berg Balance Scale (BBS), the Timed Up and Go (TUG) and the Get Up and Go (GUG) tests.Results: A total of 54 stroke survivors were included, with a mean age of 58.37 ± 12.42 years and a male predominance of 68.52%. The mean BBS score was 36.87 ± 14.34 with a minimum and a maximum of 10 and 56, respectively. Thirteen (24.07%) had balance impairments (BBS score ≤ 20), 34 (62.96%) had a TUG score ≥ 14 s (abnormal), 9 (16.67%) presented a moderate risk of falling and 6 (11.11%) presented high risk of fall with the GUG test. Post-stroke duration (odds ratio [OR] = 0.04; 95% CI: 0.04–0.30; p 0.01), severity of disability (OR = 8.33; 95% CI: 1.03–67.14; p = 0.03) and the number of physiotherapy sessions (OR = 0.18; 95% CI: 0.03–0.93; p = 0.02) were significantly associated with balance impairments.Conclusion: Our results showed that almost one quarter of stroke survivors after discharge at the University Hospital of Parakou had balance impairments. Post-stroke duration, severity of disability and the number of physiotherapy sessions were significantly associated with balance impairments.Clinical implications: [AQ1] Balance should be regularly assessed in people post-stroke. Further studies should document the content of rehabilitation and any rehabilitative efforts to improve balance in people post-stroke in Benin.


Author(s):  
Ignace N. Yao ◽  
Jean Marc L. Dia ◽  
Michelle M. Menin ◽  
Mouhedeen A. Oyelade ◽  
Corneille T. Saki ◽  
...  

Background: Describe the epidemiological and diagnostic of spontaneous aspects of early miscarriage in the department of the Gynecology Obsteric of Treichville University Teaching Hospital of   Treichville in Abidjan.Methods: A cross-sectional study was performed from January 2016 to March 2017 on patients received for an early miscarriage (gestational age less than 14 weeks of amenorrhea).Results: We recorded 337 cases of miscarriage and it shows that miscarriage was frequently estimated at 58 percent. Our patients had a average age of 32.9 years, 60.4 percent of them with primary education and 48 percent are housewives. The patients were paucigestes in 46 percent and the majority of them were nulliparous (62 percent). 6 percent with history of high blood pressure; diabetes (3 percent) and 31 percent of patients were HIV positive. Patients had pelvic pain at the admission in (55 percent). A miscarriage appears before 10 weeks of amenorrhea (76.1 percent) of cases. Ultrasound showed ovular debris (47 percent) of patients and (55.4 percent) were chromosomal abnormalities on anatomy-pathological examination.Conclusions: Spontaneous abortions are common and pathological examination is essential for diagnosis.


2021 ◽  
Vol 9 (11) ◽  
pp. 378-384
Author(s):  
F. Ihbibane ◽  
◽  
Z. Talibi Alaoui ◽  
A. Hassouni ◽  
M.El Mezouari ◽  
...  

Introduction: Opportunistic intestinal parasites (OIP) are a major cause of diarrhea in patients with HIV infection. We carried out this study to assess the prevalence and characteristics of OIP in Marrakech. Method: A retrospective cross-sectional study in a hospital environment was carried out in the infectious diseases department of Mohammed VI University Hospital, from January 2007 to October 2019. The diagnosis of OIP was made by parasitological examination of the stool, gastro panel intestinal FilmArray® multiplex PCR and / or histology. Result: Forty-eight patients with IOP were included. The prevalence of IOP was 5.17%, 40 patients had cryptosporidiosis, 6 patients had microsporidiosis and 2 patients had isosporosis. Thirty patients had co-infection with other opportunistic infections. Thirty-five patients were on ARVs. Eleven patients (22.9%) died during the study and 77.1% did well. Conclusion: The results of our study should prompt physicians treating HIV-infected patients in Morocco to request a stool exam and specific tests for Cryptosporidium, microsporidia and Isospora, especially in patients with low CD4 count.


BMJ Open ◽  
2020 ◽  
Vol 10 (1) ◽  
pp. e032513 ◽  
Author(s):  
Mirko Manchia ◽  
Pasquale Paribello ◽  
Carlo Arzedi ◽  
Alberto Bocchetta ◽  
Paola Caria ◽  
...  

IntroductionSevere psychiatric disorders are typically associated with a significant reduction in life expectancy compared with the general population. Among the different hypotheses formulated to explain this observation, accelerated ageing has been increasingly recognised as the main culprit. At the same time, telomere shortening is becoming widely accepted as a proxy molecular marker of ageing. The present study aims to fill a gap in the literature by better defining the complex interaction/s between inflammation, age-related comorbidities, telomere shortening and gut microbiota in psychiatric disorders.Methods and analysisA cross-sectional study is proposed, recruiting 40 patients for each of three different diagnostic categories (bipolar disorder, schizophrenia and major depressive disorder) treated at the Section of Psychiatry and at the Unit of Clinical Pharmacology of the University Hospital Agency of Cagliari (Italy), compared with 40 age-matched and sex-matched non-psychiatric controls. Each group includes individuals suffering, or not, from age-related comorbidities, to account for the impact of these medical conditions on the biological make-up of recruited patients. The inflammatory state, microbiota composition and telomere length (TL) are assessed.Ethics and disseminationThe study protocol was approved by the Ethics Committee of the University Hospital Agency of Cagliari (PG/2018/11693, 5 September 2018). The study is conducted in accordance with the principles of good clinical practice and the Declaration of Helsinki, and in compliance with the relevant Italian national legislation. Written, informed consent is obtained from all participants. Participation in the study is on a voluntary basis only. Patients will be part of the dissemination phase of the study results, during which a local conference will be organised and families of patients will also be involved. Moreover, findings will be published in one or more research papers and presented at national and international conferences, in posters or oral communications.


Nutrients ◽  
2020 ◽  
Vol 12 (6) ◽  
pp. 1765
Author(s):  
Mohamad Jawhara ◽  
Signe Bek Sørensen ◽  
Berit Lilienthal Heitmann ◽  
Þórhallur Ingi Halldórsson ◽  
Andreas Kristian Pedersen ◽  
...  

The Colonic Mucosal Barrier (CMB) is the site of interaction between the human body and the colonic microbiota. The mucus is the outer part of the CMB and is considered as the front-line defense of the colon. It separates the host epithelial lining from the colonic content, and it has previously been linked to health and diseases. In this study, we assessed the relationship between red meat and whole-grain intake and (1) the thickness of the colonic mucus (2) the expression of the predominant mucin gene in the human colon (MUC2). Patients referred to colonoscopy at the University Hospital of Southern Denmark- Sonderjylland were enrolled between June 2017 and December 2018, and lifestyle data was collected in a cross-sectional study design. Colonic biopsies, blood, urine, and fecal samples were collected. The colonic mucus and bacteria were visualized by immunostaining and fluorescence in situ hybridization techniques. We found a thinner mucus was associated with high red meat intake. Similarly, the results suggested a thinner mucus was associated with high whole-grain intake, albeit to a lesser extent than red meat. This is the first study assessing the association between red meat and whole-grain intake and the colonic mucus in humans. This study is approved by the Danish Ethics Committee (S-20160124) and the Danish Data Protecting Agency (2008-58-035). A study protocol was registered at clinical trials.gov under NCT04235348.


2007 ◽  
Vol 65 (2A) ◽  
pp. 218-221 ◽  
Author(s):  
Cláudia Regina Beuter ◽  
Fleming Salvador Pedroso ◽  
Ricardo César Mazetto ◽  
Cassandra Trojahn dos Santos ◽  
Ângela Garcia Rossi

A non-comparable, individual, observational and contemporary cross-sectional study in newborns was made to determine the dynamic lateralization in the head turning after release from the midline and its relationship with obstetric variables. From October to December of 2005, 320 newborns were admitted to the Adjacent Lodgings of the University Hospital of Santa Maria. From those, 89 were selected for assessment of the vestibular function since they have had previously fetal static control through ultrasound. Our results show that the right-sided head lateralization was significantly greater than the left-sided. The predominancy of the lateralization towards the right side also occurred in cephalic presentations and left-sided back, however these were not significant. Results corroborate with the existing literature and suggest an association between fetal static and vestibular function.


2020 ◽  
Vol 4 (1) ◽  
pp. 91-101
Author(s):  
Ines Dobrinić ◽  
Slađana Režić

Introduction. Visits to patients are part of a positive and effective strategy of helping patients and their families to better adapt to the stress caused by a patient’s admission to an intensive care unit (ICU). Aim. To determine the ICU nurses’ perception of visits to patients. Methods. The study was conducted at the University Hospital Centre Zagreb (UHC). The cross-sectional study included nurses who work in ICUs. An anonymous, self-designed questionnaire was used and filled in by 44 respondents. The questionnaire consisted of 17 closed-ended questions pertaining to demographic data, questions related to information on visits and questions about the concept of open visits. Results. Out of the total number of 44 respondents, 25 respondents stated that their ICU has booklets about the manner of visits and visiting hours, and that they hand them out to families, while 19 respondents stated that they do not have such booklets. 61% of the respondents feel they have sufficient training to communicate with the patient’s family. 41% of the respondents said that the visits had a positive effect on the patient’s condition and only 2% stated that the visits had no positive effect. 57 % of the respondents think that visits sometimes have a positive effect on the patient’s condition. Of the total number of respondents, 84% feel that visiting hours should be limited. Respondents feel that visits sometimes impede them in their work (66%), while 59% of the respondents feel that visits help spread infections. Out of the total number of respondents, only 32% of them stated that they were familiar with the open ICU concept. Conclusion. More than half of the respondents stated that they have a written visiting policy on ICU wards, and that they are trained to communicate with the family members of patients. Most respondents feel that visits contribute to the spread of infections and that they would limit children’s visits to the ICU. The respondents’ poor knowledge of the open ICU concept creates one of the barriers to introducing it in their wards.


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