scholarly journals What Can We Learn from Burkina Faso COVID-19 Data? Using Phenomenological Models to Characterize the Initial Growth Dynamic of the Outbreak and to Generate Short-Term Forecasts

Author(s):  
Toussaint Rouamba ◽  
Sekou Samadoulougou ◽  
Bruno Bonnechère ◽  
Benjamin Chiêm ◽  
Fati Kirakoya-Samadoulougou

On 9 March 2020, two cases of COVID-19 were reported in Burkina Faso. As of 10 April 2020, a total number of 484 cases (404 cases in the Kadiogo province) were reported nationwide. Real-time forecasts of COVID-19 are important to inform decision-making in the country. Here, we propose an approach that tests the performance of four models (Exponential Growth model, the Generalized Growth model (GGM), the Generalized Logistic Growth, and Richards Growth model) to select the model that best fit data and to generate short-term forecasting (5-, 10-, and 15-day forecasts from 11 to 25 April 2020) in Kadiogo, the epicenter of the outbreak. Using daily number of confirmed COVID-19 cases, the results suggests that GGM performed the best out of the 4 models. Overall, our GGM predictions suggested an average total number of cumulative cases of 514 (95% CI, 464–559), 629 (95% CI, 559–691), and 750 (95% CI, 661–840) between 11 to 15 April, 16 to 20 April, and 20 to 25 April 2020, respectively. COVID-19 in this province was best approximated by sub exponential growth rather than exponential or logistic growth. Current data suggest that COVID-19 cases would continue to increase over the next 15-days.

2020 ◽  
Vol 9 (2) ◽  
pp. 596 ◽  
Author(s):  
Kimberlyn Roosa ◽  
Yiseul Lee ◽  
Ruiyan Luo ◽  
Alexander Kirpich ◽  
Richard Rothenberg ◽  
...  

The ongoing COVID-19 epidemic continues to spread within and outside of China, despite several social distancing measures implemented by the Chinese government. Limited epidemiological data are available, and recent changes in case definition and reporting further complicate our understanding of the impact of the epidemic, particularly in the epidemic’s epicenter. Here we use previously validated phenomenological models to generate short-term forecasts of cumulative reported cases in Guangdong and Zhejiang, China. Using daily reported cumulative case data up until 13 February 2020 from the National Health Commission of China, we report 5- and 10-day ahead forecasts of cumulative case reports. Specifically, we generate forecasts using a generalized logistic growth model, the Richards growth model, and a sub-epidemic wave model, which have each been previously used to forecast outbreaks due to different infectious diseases. Forecasts from each of the models suggest the outbreaks may be nearing extinction in both Guangdong and Zhejiang; however, the sub-epidemic model predictions also include the potential for further sustained transmission, particularly in Zhejiang. Our 10-day forecasts across the three models predict an additional 65–81 cases (upper bounds: 169–507) in Guangdong and an additional 44–354 (upper bounds: 141–875) cases in Zhejiang by February 23, 2020. In the best-case scenario, current data suggest that transmission in both provinces is slowing down.


2020 ◽  
Author(s):  
Farhan Saif

We present a real-time forecast of COVID-19 in Pakistan that is important for decision-making to control the spread of the pandemic in the country. The study helps to develop an accurate plan to eradicate the COVID-19 by taking calculated steps at the appropriate time, that are crucial in the absence of a tested medicine. We use four phenomenological mathematical models, namely Discrete Exponential Growth model, the Discrete Generalized Growth model, the Discrete Generalized Logistic Growth, and Discrete Generalize Richards Growth model. Our analysis explains the important characteristics quantitatively. The study leads to understand COVID-19 pandemic in Pakistan in three evolutionary stages, and provides understanding to control its spread in the short time domain and in the long term domain. For the reason the study is helpful in devising the measures to handle the emerging threat of similar outbreaks in other countries.


2021 ◽  
Vol 18 (1) ◽  
Author(s):  
Hiroaki Murayama ◽  
Taishi Kayano ◽  
Hiroshi Nishiura

Abstract Background In Japan, a part of confirmed patients’ samples have been screened for the variant of concern (VOC), including the variant alpha with N501Y mutation. The present study aimed to estimate the actual number of cases with variant alpha and reconstruct the epidemiological dynamics. Methods The number of cases with variant alpha out of all PCR confirmed cases was estimated, employing a hypergeometric distribution. An exponential growth model was fitted to the growth data of variant alpha cases over fourteen weeks in Tokyo. Results The weekly incidence with variant alpha from 18–24 January 2021 was estimated at 4.2 (95% confidence interval (CI): 0.7, 44.0) cases. The expected incidence in early May ranged from 420–1120 cases per week, and the reproduction number of variant alpha was on the order of 1.5 even under the restriction of contact from January-March, 2021, Tokyo. Conclusions The variant alpha was predicted to swiftly dominate COVID-19 cases in Tokyo, and this has actually occurred by May 2021. Devising the proposed method, any country or location can interpret the virological sampling data.


2001 ◽  
Author(s):  
Peter Vadasz ◽  
Alisa S. Vadasz

Abstract A neoclassical model is proposed for the growth of cell and other populations in a homogeneous habitat. The model extends on the Logistic Growth Model (LGM) in a non-trivial way in order to address the cases where the Logistic Growth Model (LGM) fails short in recovering qualitative as well as quantitative features that appear in experimental data. These features include in some cases overshooting and oscillations, in others the existence of a “Lag Phase” at the initial growth stages, as well as an inflection point in the “In curve” of the population size. The proposed neoclassical model recovers also the Logistic Growth Curve as a special case. Comparisons of the solutions obtained from the proposed neoclassical model with experimental data confirm its quantitative validity, as well as its ability to recover a wide range of qualitative features captured in experiments.


2020 ◽  
Vol 111 (8) ◽  
pp. 629-638
Author(s):  
A. Tejera-Vaquerizo ◽  
J. Cañueto ◽  
A. Toll ◽  
J. Santos-Juanes ◽  
A. Jaka ◽  
...  

2021 ◽  
Author(s):  
Miguel López ◽  
Alberto Peinado ◽  
Andrés Ortiz

AbstractSince the first case reported of SARS-CoV-2 the end of December 2019 in China, the number of cases quickly climbed following an exponential growth trend, demonstrating that a global pandemic is possible. As of December 3, 2020, the total number of cases reported are around 65,527,000 contagions worldwide, and 1,524,000 deaths affecting 218 countries and territories. In this scenario, Spain is one of the countries that has suffered in a hard way, the ongoing epidemic caused by the novel coronavirus SARS-CoV-2, namely COVID-19 disease. In this paper, we present the utilization of phenomenological epidemic models to characterize the two first outbreak waves of COVID-19 in Spain. The study is driven using a two-step phenomenological epidemic approach. First, we use a simple generalized growth model to fit the main parameters at the early epidemic phase; later, we apply our previous finding over a logistic growth model to that characterize both waves completely. The results show that even in the absence of accurate data series, it is possible to characterize the curves of case incidence, and even construct short-term forecast in the near time horizon.


2021 ◽  
Vol 38 (2) ◽  
pp. 229-236
Author(s):  
Ayşe Van ◽  
Aysun Gümüş ◽  
Melek Özpiçak ◽  
Serdar Süer

By the study's coverage, 522 individuals of tentacled blenny (Parablennius tentacularis (Brünnich, 1768)), were caught with the bottom trawl operations (commercial fisheries and scientific field surveys) between May 2010 and March 2012 from the southeastern Black Sea. The size distribution range of the sample varied between 4.8-10.8 cm. The difference between sex length (K-S test, Z=3.729, P=0.000) and weight frequency distributions (K-S test, Z=3.605, P=0.000) was found to be statistically significant. The length-weight relationship models were defined as isometric with W = 0.009L3.034 in male individuals and positive allometric with W = 0.006L3.226 in female individuals. Otolith and vertebra samples were compared for the selection of the most accurate hard structure that can be used to determine the age. Otolith was chosen as the most suitable hard structure. The current data set was used to predict the best growth model. For this purpose, the growth parameters were estimated with the widely used von Bertalanffy, Gompertz and Logistic growth functions. Akaike's Information Criterion (AIC), Lmak./L∞ ratio, and R2 criteria were used to select the most accurate growth models established through these functions. Model averaged parameters were calculated with multi-model inference (MMI): L'∞ = 15.091 cm, S.E. (L'∞) = 3.966, K'= 0.232 year-1, S.E. (K') = 0.122.


Author(s):  
Yuexing Hao ◽  
Glenn Shafer

For more than half a century, plastic prod-ucts have been a part of people’s lives. When plastic waste is thrown into nature, it can cause a sequence of dangerous effects. Previous researchers esti-mated that global plastic waste in 2020 will be more than 400 million tons. To reduce plastic waste, they built scientific models to analyze the sources of plas-tic and provided solutions for regenerating these plastic wastes. However, their models are static and inaccurate, which may cause some false predictions.In this paper, we first observe the distribution of the real-world plastic waste data. Then, we build simple exponential growth model and logistics model to match these data. By testing different models on our plots, we discover that the SELF-ADAPTIVE MODEL is the best to describe and correctly predict our future plastic waste production, as this model combines the benefits of SIMPLE EXPONENTIAL GROWTH MODEL and the LOGISTIC MODEL. The self-Adaptive model has the potential to minimize the error rate and make the predictions more accurate. Based on this model, we can develop more accurate and informative solu-tions for the real-world plastic problems.


Author(s):  
Ajit Kumar Pasayat ◽  
Satya Narayan Pati ◽  
Aashirbad Maharana

In this study, we analyze the number of infected positive cases of COVID-19 outbreak with concern to lockdown in India in the time window of February 11th 2020 to Jun 30th 2020. The first case in India was reported in Kerala on January 30th 2020. To break the chain of spreading, Government announced a nationwide lockdown on March 24th 2020, which is increased two times. The Ongoing lockdown 3.0 is over on May 18th, 2020. We derived how the lockdown relaxation is going to impact on containment of the outbreak. Here the Exponential Growth Model has been used to derive the epidemic curve based on the data collected from February 11th 2020, to May 11th 2020, and the Machine Learning based Linear Regression model that gives the epidemic curve to predict the cases with the continuous flow of the lockdown. We estimate that if the lockdown is continuing with more relaxation, then the estimated infected cases reach up to 1.16 crores by June 30th 2020, and the lockdown would persist with current restriction, then the expected predicted infected cases are 5.69 lacs. The Exponential Growth Model and the Linear Regression Model are advantageous to predict the number of affected cases of COVID-19. These models can be used for forecasting in long term intervals. It shows from our result that lockdown with certain restriction has a vital role in preventing the spreading of this epidemic in this current situation.


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