Inverse association of plasma hydrogen sulfide levels with visceral fat area among Chinese young men: a cross-sectional study

AbstractBackground and Aims: The aim of the present study was to investigate the relationship between visceral fat area (VFA), estimated by bioimpedance, and cardiovascular risk factors independent of BMI and waist circumference in a cohort of Romanian patients. Material and Methods: This was a cross-sectional study, in which were collected data from 751 patients ≥18 years of age from Cluj-Napoca. Anthropometric, biochemistry, body composition and medical history parameters were recorded from patients’ files. Results: Compared with the participants with VFA <100 cm2, those with VFA ≥100 cm2had significantly worse levels of the laboratory parameters describing the glycemic metabolism, lipid metabolism and liver functions (p <0.05 for all). A higher percentage of participants with VFA ≥100 cm2had diabetes, obesity, hypertension, hypertriglyceridemia and hypo-HDL cholesterolemia (p <0.05 for all). VFA was correlated with systolic and diastolic blood pressure, total and LDL-cholesterol levels, triglycerides, ALT, previous diagnosis of diabetes, hypertriglyceridemia and hypo-HDL cholesterolemia independent of BMI and waist circumference. Conclusions: Among this cohort of Romanian adults, an increasing level of visceral adiposity was correlated with worse lipid and glucose metabolism parameters as well as with increased levels of ALT, which probably reflects liver fat deposition.

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The visceral fat area to leg muscle mass ratio is significantly associated with the risk of hyperuricemia among women: a cross-sectional study

Biology of Sex Differences ◽

10.1186/s13293-021-00360-9 ◽

2021 ◽

Vol 12 (1) ◽

Author(s):

Xiao-He Wang ◽

Wei-Ran Jiang ◽

Min-Ying Zhang ◽

Ying-Xin Shi ◽

Yun-Ping Ji ◽

...

Keyword(s):

Visceral Fat ◽

Density Lipoprotein ◽

Positive Association ◽

Cross Sectional Study ◽

Sectional Study ◽

Significant Positive Association ◽

Visceral Fat Area ◽

Cross Sectional ◽

Menopausal Women ◽

Leg Muscle

Abstract Background A significant positive association was found in previous studies among obesity, visceral fat accumulation, and hyperuricemia. The purpose of this study was to explore the association between the ratio of visceral fat area to leg muscle mass (VFA-to-LMM) and hyperuricemia, and verify the role of gender differences in the association. Methods A total of 3393 (43.3% are men) participants from Tianjin Union Medical Center-Health Management Center were recruited for this cross-sectional study. The VFA-to-LMM ratio was used as the independent variable. Hyperuricemia, a serum uric acid level ≥ 416 μmol/L in men and in menopausal women and ≥ 357 μmol/L in premenopausal women, was used as the dependent variable. Multiple logistic regression analysis was used to estimate the odds ratio and the 95% confidence interval between the VFA-to-LMM ratio and hyperuricemia. Results The overall prevalence of hyperuricemia was 14.8% (8.9% in women, and 22.5% in men). After adjustment by age, smoking status (for males), menopause status (for females), drinking status, exercise frequency, blood pressure, alanine aminotransferase, fasting plasma glucose, triglycerides, low-density lipoprotein cholesterol, high-density lipoprotein cholesterol, creatinine, and history of diseases, a strong positive association was found between the VFA-to-LMM ratio and hyperuricemia in both men (4th vs. 1st quartile 1.60, 95%CI: 1.03–2.49) and women (4th vs. 1st quartile 5.22, 95%CI: 2.44–12.56). After additional adjustment by BMI, there was still a significant positive association in women (4th vs. 1st quartile 2.57, 95%CI: 1.06–6.77). The results of subgroup analysis showed that pre-menopausal women (4th vs. 1st quartile OR: 3.61) have a higher risk of hyperuricemia than postmenopausal women (4th vs. 1st quartile OR: 1.94) with the increase of the VFA-to-LMM ratio. Besides, the interaction analysis results showed the highest risk of hyperuricemia when VFA and LMM were both in the highest quantile (OR: 11.50; 95% CI: 4.86–31.98). Conclusion The VFA-to-LMM ratio was positively associated with the risk of hyperuricemia in women after adjustment by confounders. Pre-menopausal women have a higher risk of hyperuricemia than postmenopausal women with the increase of the VFA-to-LMM ratio. In addition, the highest risk of hyperuricemia was demonstrated when both VFA and LMM were at the highest quartile.

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Visceral Fat Area to Leg Muscle Mass Ratio Are Significantly Associated With the Risk of Hyperuricemia Among Women: A Cross-sectional Study

10.21203/rs.3.rs-28417/v1 ◽

2020 ◽

Author(s):

Xiao-He WANG ◽

Wei-Ran JIANG ◽

Min-Ying ZHANG ◽

Ying-Xin SHI ◽

Yun-Ping JI ◽

...

Keyword(s):

Muscle Mass ◽

Visceral Fat ◽

Density Lipoprotein ◽

Positive Association ◽

Cross Sectional Study ◽

Sectional Study ◽

Significant Positive Association ◽

Visceral Fat Area ◽

Cross Sectional ◽

Leg Muscle

Abstract Background: Previous studies have found a significant positive association between obesity, visceral fat accumulation and hyperuricemia. The purpose of the study was to explore the association between the ratio of visceral fat area to leg muscle mass(VFA-to-LMM) and hyperuricemia, and verify the role of sex differences in the association.Methods:In this cross-sectional study, a total of 3393 (43.3% for men) participants from Tianjin Union Medical Center-Health Management Center were recruited. Body composition were measured by multielectrode bioelectrical impedance analyzer. The VFA-to-LMM ratio was used as independent variable. Hyperuricemia, defined as a serum uric acid level ≥ 416 μmol/L in men and menopausal women, and ≥ 357 μmol/L in premenopausal women, was used as the dependent variable. Multiple logistic regression analysis was used to estimate the odds ratio and 95% confidence interval between VFA-to-LMM ratio and hyperuricemia.Results:The overall prevalence of hyperuricemia was 14.8%, and the prevalence of hyperuricemia in women (8.9%) was significantly lower than that in men (22.5%). After adjustment for age, smoking status (for males), menopause status (for females), drinking status, exercise frequency, blood pressure, alanine aminotransferase, fasting plasma glucose, triglycerides, low-density lipoprotein cholesterol, high-density lipoprotein cholesterol, creatinine, and history of diseases, a strong positive association was observed between VFA-to-LMM ratio and hyperuricemiain bothmen (4th vs. 1st quartile 1.60, 95%CI: 1.03-2.49) and women (4th vs. 1st quartile 5.22, 95%CI: 2.44-12.56).After additionally adjustment for BMI, there was still a significant positive association in women (4th vs. 1st quartile 2.57, 95%CI: 1.06-6.77), while the association disappeared in men(4th vs. 1st quartile 0.97, 95%CI: 0.55-1.70).Conclusions:The VFA-to-LMM ratio was positively associated with the risk of hyperuricemia in women after adjustments for confounders. In addition, the highest risk of hyperuricemia was observed when both VFA and LMM were at the highest quartile. However, well-controlled prospective studies are needed to further confirm the causality between VFA-to-LMM ratio and hyperuricemia.

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Association between increased visceral fat area and alterations in plasma fatty acid profile in overweight subjects: a cross-sectional study

Lipids in Health and Disease ◽

10.1186/s12944-017-0642-z ◽

2017 ◽

Vol 16 (1) ◽

Cited By ~ 9

Author(s):

Miso Kang ◽

Ayoung Lee ◽

Hye Jin Yoo ◽

Minjoo Kim ◽

Minkyung Kim ◽

...

Keyword(s):

Fatty Acid ◽

Fatty Acid Profile ◽

Visceral Fat ◽

Cross Sectional Study ◽

Plasma Fatty Acid ◽

Sectional Study ◽

Visceral Fat Area ◽

Cross Sectional ◽

Overweight Subjects ◽

Plasma Fatty Acid Profile

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The association between meat consumption and the metabolic syndrome: a cross-sectional study and meta-analysis

British Journal Of Nutrition ◽

10.1017/s0007114521002452 ◽

2021 ◽

pp. 1-15

Author(s):

Khemayanto Hidayat ◽

Wan-Zhan Zhu ◽

Si-Min Peng ◽

Jin-Jin Ren ◽

Meng-Lan Lu ◽

...

Keyword(s):

Metabolic Syndrome ◽

Fish Consumption ◽

Meta Analysis ◽

Meat Consumption ◽

Cross Sectional Study ◽

Red Meat ◽

Inverse Association ◽

Sectional Study ◽

Cross Sectional ◽

The Metabolic Syndrome

Abstract The findings regarding the associations between red meat, fish and poultry consumption, and the metabolic syndrome (Mets) have been inconclusive, and evidence from Chinese populations is scarce. A cross-sectional study was performed to investigate the associations between red meat, fish and poultry consumption, and the prevalence of the Mets and its components among the residents of Suzhou Industrial Park, Suzhou, China. A total of 4424 participants were eligible for the analysis. A logistic regression model was used to estimate the OR and 95 % CI for the prevalence of the Mets and its components according to red meat, fish and poultry consumption. In addition, the data of our cross-sectional study were meta-analysed under a random effects model along with those of published observational studies to generate the summary relative risks (RR) of the associations between the highest v. lowest categories of red meat, fish and poultry consumption and the Mets and its components. In the cross-sectional study, the multivariable-adjusted OR for the highest v. lowest quartiles of consumption was 1·23 (95 % CI 1·02, 1·48) for red meat, 0·83 (95 % CI 0·72, 0·97) for fish and 0·93 (95 % CI 0·74, 1·18) for poultry. In the meta-analysis, the pooled RR for the highest v. lowest categories of consumption was 1·20 (95 % CI 1·06, 1·35) for red meat, 0·88 (95 % CI 0·81, 0·96) for fish and 0·97 (95 % CI 0·85, 1·10) for poultry. The findings of both cross-sectional studies and meta-analyses indicated that the association between fish consumption and the Mets may be partly driven by the inverse association of fish consumption with elevated TAG and reduced HDL-cholesterol and, to a lesser extent, fasting plasma glucose. No clear pattern of associations was observed between red meat or poultry consumption and the components of the Mets. The current findings add weight to the evidence that the Mets may be positively associated with red meat consumption, inversely associated with fish consumption and neutrally associated with poultry consumption.

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Inverse Association Between Metabolic Syndrome and Altitude: A Cross-Sectional Study in an Adult Population of Ecuador

Frontiers in Endocrinology ◽

10.3389/fendo.2018.00658 ◽

2018 ◽

Vol 9 ◽

Cited By ~ 3

Author(s):

Amaya Lopez-Pascual ◽

Jéssica Arévalo ◽

J. Alfredo Martínez ◽

Pedro González-Muniesa

Keyword(s):

Metabolic Syndrome ◽

Adult Population ◽

Cross Sectional Study ◽

Inverse Association ◽

Sectional Study ◽

Cross Sectional

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Nutritional knowledge and body mass index: A cross-sectional study

Revista da Associação Médica Brasileira ◽

10.1590/1806-9282.63.09.736 ◽

2017 ◽

Vol 63 (9) ◽

pp. 736-740 ◽

Cited By ~ 4

Author(s):

Julia Luzzi Valmórbida ◽

Maíra Ribas Goulart ◽

Fernanda Michielin Busnello ◽

Lúcia Campos Pellanda

Keyword(s):

Body Mass Index ◽

Nutritional Status ◽

Body Mass ◽

Cross Sectional Study ◽

Noncommunicable Diseases ◽

Inverse Association ◽

Sectional Study ◽

Cross Sectional ◽

Food And Nutrition ◽

Level Of Knowledge

Summary Objective: To verify the knowledge about food and nutrition and its association with the nutritional status of obese patients with noncommunicable diseases (NCDs), and to identify the relationship between information sources and level of knowledge. Method: Cross-sectional study that included 263 outpatients of a cardiology referral hospital in Porto Alegre, Rio Grande do Sul, Brazil. The participants filled out a questionnaire on socioeconomic data and knowledge about food and nutrition and had their nutritional status evaluated by body mass index (BMI), waist circumference (WC) and waist-hip ratio (WHR). Results: BMI showed a significant inverse association with the percentage of correct answers (p=0.002), as well as WC (p=0.000) and WHR (p<0.001). This was also true for education (p<0.001) and female gender (p=0.005) compared to males. More than 60% of patients reported using television and 23% reported using newspaper as sources of nutritional information. Conclusion: Our study revealed a significant association between BMI and the level of knowledge about foods, showing that there is need for more information on obesity-related NCDs for greater understanding by patients.

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Consumption of Sugar-Sweetened or Artificially Sweetened Beverages and Semen Quality in Young Men: A Cross-Sectional Study

International Journal of Environmental Research and Public Health ◽

10.3390/ijerph19020682 ◽

2022 ◽

Vol 19 (2) ◽

pp. 682

Author(s):

Maiken Meldgaard ◽

Nis Brix ◽

Anne Gaml-Sørensen ◽

Andreas Ernst ◽

Cecilia Høst Ramlau-Hansen ◽

...

Keyword(s):

Negative Binomial ◽

Semen Quality ◽

Young Men ◽

Cross Sectional Study ◽

Male Participant ◽

Negative Binomial Regression Model ◽

Sectional Study ◽

Cross Sectional ◽

Sweetened Beverages ◽

Artificially Sweetened Beverages

Background: Existing literature suggests that frequent consumption of sugar-sweetened drinks may be associated with lower semen quality. Studies performed in mice suggest a dose-response relationship between intake of saccharin or aspartame, two artificial sweeteners, and sperm and testis function. Methods: A cross-sectional study based on data from The Fetal Programming of Semen Quality (FEPOS) Cohort, including 1047 young men (mean age = 19 years) was performed. Each male participant completed an online questionnaire on health, health behavior and diet, and provided a semen sample. The associations between consumption of sugar-sweetened or artificially sweetened beverages (moderate ≥ 3 days/week; infrequent < 3 days/week) and semen quality were analyzed using a multivariable, negative, binomial regression model. Results: Sugar-sweetened or artificially sweetened beverage consumption was not strongly associated with either semen volume, sperm concentration, total sperm count or total motility in young men. The proportion of morphologically normal sperm was 11% lower (0.89 (95% CI 0.76, 1.04)) for moderate (≥3 days/week) consumption of artificially sweetened beverages relative to infrequent (<3 days/week). Conclusion: Consumption of sugar-sweetened or artificially sweetened beverages, at the levels present in this study had limited effect on the measured markers of semen quality in young men.

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