scholarly journals The Right Kind of Pooled Testing for the Novel Coronavirus: First, Do No Harm

2020 ◽  
Vol 110 (12) ◽  
pp. 1772-1773
Author(s):  
Eugene Litvak ◽  
Susan Dentzer ◽  
Marcello Pagano
Keyword(s):  
The Novel ◽  
Pooled Testing ◽  
Do No Harm ◽  
Novel Coronavirus ◽  
The Right

scholarly journals Pooling of coronavirus tests under unknown prevalence

2020 ◽  
Vol 148 ◽  
Author(s):  
A. Pikovski ◽  
K. Bentele
Keyword(s):  
Diagnostic Testing ◽  
False Positives ◽  
Pool Size ◽  
The Novel ◽  
Average Model ◽  
Pooled Testing ◽  
Testing Protocol ◽  
Test Errors ◽  
Novel Coronavirus ◽  
Dilution Effects

Abstract Diagnostic testing for the novel coronavirus is an important tool to fight the coronavirus disease (Covid-19) pandemic. However, testing capacities are limited. A modified testing protocol, whereby a number of probes are ‘pooled’ (i.e. grouped), is known to increase the capacity for testing. Here, we model pooled testing with a double-average model, which we think to be close to reality for Covid-19 testing. The optimal pool size and the effect of test errors are considered. The results show that the best pool size is three to five, under reasonable assumptions. Pool testing even reduces the number of false positives in the absence of dilution effects.

scholarly journals The First Case of Reactive Arthritis Associated with SARS-CoV-2-Infection in A 4-Year Old Child

2020 ◽  
Author(s):  
Stephanie Gabriele Werner ◽  
Hans-Eckhard Langer
Keyword(s):  
Severe Acute Respiratory Syndrome ◽  
Reactive Arthritis ◽  
Virus Disease ◽  
The Novel ◽  
Case Presentation ◽  
Corona Virus ◽  
First Case ◽  
Novel Coronavirus ◽  
The Right

Abstract Background: The novel coronavirus SARS‐CoV‐2 (severe acute respiratory syndrome coronavirus 2) and its associated disease COVID‐19 (Corona Virus Disease 19) has become a worldwide pandemic since its first cases in December 2019 in Wuhan Province in China. In Germany the pandemic started in February 2020.Case presentation: A 4 year old boy was presented and suffered from pain in the right hip. Arthrosonography demonstrated a significant effusion in the involved joint. The extended history revealed a slight but long lasting cold before. Serological findings were inconspicuous except for positive ELISA (Enzyme-linked Immuno Sorbent Assay) - test for SARS-CoV-2. Conclusion: In conclusion we believe that we can report the first case of reactive arthritis associated with SARS-CoV-2 in children.

scholarly journals Impact of COVID-19 Lockdown on Sleep Quality in Students

2021 ◽  
pp. 265-269
Author(s):  
Pragya Tiwari ◽  
Minal Trivedi ◽  
Apeksha Kesarwani ◽  
Ojaswi Gopale
Keyword(s):  
Digital Media ◽  
Social Life ◽  
Daily Routine ◽  
The Novel ◽  
Laptop Computer ◽  
Periodic State ◽  
Quality Sleep ◽  
State Of Rest ◽  
Novel Coronavirus ◽  
The Right

A periodic state of rest accompanied by varying degrees of unconsciousness and relative inactivity is referred as sleep; in another way is a state in which an individual lacks conscious awareness of environment surroundings. Quality sleep and getting enough of it at the right times is as essential for survival just as food and water. Without sleep our brain can’t learn and create new memories, making it harder to concentrate and respond quickly. The Novel Coronavirus (also known as COVID-19) ushered the world into uncharted waters. In India, strict lockdown was imposed in three phases from March to June 2020 for the containment of the COVID-19 pandemic. At this juncture, we attempted to assess how derailment of social life due to imposed social isolation, leading to compromised sleep in the present scenario affects circadian driven sleep-wake pattern and other lifestyle related behaviour. A brief survey on affected sleep pattern of people during corona pandemic was conducted to understand the possible alterations in sleep-wake schedules and the daily routine related activities such as exposure time to digital media (i.e., TV, laptop/computer/mobile, etc.) as a consequence of lockdown.

scholarly journals The impact of digitization on economy in the context of the Coronavirus pandemic

2021 ◽  
Vol 92 ◽  
pp. 01018
Author(s):  
Crina Ionescu ◽  
Mihaela Iordache ◽  
Emilia Țițan
Keyword(s):  
Quantitative Research ◽  
National Level ◽  
Value Added ◽  
The Novel ◽  
Negative Effects ◽  
Global Pandemic ◽  
The Face ◽  
Novel Coronavirus ◽  
The Right ◽  
The Impact

Research background: As COVID-19 is posing unprecedented challenges, the governments as well as the individuals have to adapt to the shift towards a new lifestyle. The preventing measures against the spread of the novel coronavirus has important consequences on economy sectors both at global and national level. In this regard, it is the right time to accelerate the development of the digital tools and technologies that can help neutralize or at least mitigate the negative effects of the COVID-19. Purpose of the article: Therefore, the aim of this paper is to evaluate the current situation of digitization, focusing on the main transformations in recent months. Methods: Throughout the paper, there can be distinguished both qualitative and quantitative approach. The methods used include a secondary research from official information and primary quantitative research obtained from a conducted survey that explains the importance and the impact of digitization on economy in the face of a global pandemic. Findings & Value added: The article highlights the impact of digitization on the economy by comparing the findings from Romanian economy with other EU countries. It is noted that in areas where the digitization was more developed or where the adaptation to the new conditions imposed by the crisis generated by COVID-19 has been faster, the impact was significantly lower as well.

scholarly journals Remarks on pooling Coronavirus tests

2020 ◽  
Author(s):  
Alexander Pikovski ◽  
Kajetan Bentele
Keyword(s):  
Diagnostic Testing ◽  
False Positives ◽  
Pool Size ◽  
The Novel ◽  
Average Model ◽  
Pooled Testing ◽  
Testing Protocol ◽  
Test Errors ◽  
Novel Coronavirus ◽  
Dilution Effects

AbstractDiagnostic testing for the novel Coronavirus is an important tool to fight the Covid-19 pandemic. However, testing capacities are limited. A modified testing protocol, whereby a number of probes are “pooled” (that is, grouped), is known to increase the capacity for testing. Here, we model pooled testing with a double-average model, which we think to be close to reality for Covid-19 testing. The optimal pool size and the effect of test errors are considered. Results show that the best pool size is three to five, under reasonable assumptions. Pool testing even reduces the number of false positives in the absence of dilution effects.

Healthcare Quality in the Pandemic Aftermath

2020 ◽  
Vol 9 (4) ◽  
pp. 4-7
Author(s):  
Anastasius S. Moumtzoglou
Keyword(s):  
Health Care Workers ◽  
Healthcare Professionals ◽  
Theory And Practice ◽  
Formal Training ◽  
The Novel ◽  
Educational Backgrounds ◽  
Care Workers ◽  
Do No Harm ◽  
Novel Coronavirus ◽  
And Training

The COVID-19 pandemic is putting massive stress on the formal training of healthcare professionals, their creed to do no harm, as well as the patient safety movement. So far, we have explicitly been teaching healthcare professionals that the best way of treating a patient is through its vicinity with multiple providers. Moreover, healthcare education requires a pack of health care workers from varied educational backgrounds and training levels for the nuances of a disease. However, the novel coronavirus (COVID-19), a respiratory disease that has spread to many countries around the world, affects not only all aspects of daily life but also organizational culture and values of healthcare. In this context, COVID-19 introduced an exponential threat to the theory and practice of quality.

Oral Language Assessment LITeracy: Choosing the Right Assessment in the Time of COVID

2020 ◽  
Author(s):  
Rihana Shiri Mason ◽  
Lisa Fitton ◽  
Ryan L. James ◽  
Yaacov Petscher
Keyword(s):  
Learning Environments ◽  
Oral Language ◽  
School Environment ◽  
Language Assessment ◽  
Assessment Literacy ◽  
Assessment Practices ◽  
The Novel ◽  
Due Diligence ◽  
Novel Coronavirus ◽  
The Right

The novel coronavirus (COVID-19) has altered learning environments. These changes have shed light on several factors that make assessing oral language skill, a foundational component of reading development, even more challenging under current conditions. Oral language is the way that we communicate our thoughts and ideas. Three factors related to ways in which we can raise our oral language assessment LITeracy by considering children’s: 1) Language variation, 2) Individual differences, and 3) the Technological considerations of the school environment during the upcoming year are discussed. Taking account of these three factors is a first step in ensuring equitable assessment. In order to make strides in preventing inequitable assessment practices we provide general recommendations to help overcome the challenges faced in the current climate and future learning environments. Choosing the right oral language assessment means: 1) being inclusive of the language, dialect, and individual variation that is reflected in your classroom. 2) embracing all of the oral language 3) anticipating how the data from an assessment can be linked to instructional practice and 4) making time to do your due diligence.

scholarly journals COVID-19: The Potential Treatment of Pulmonary Fibrosis Associated with SARS-CoV-2 Infection

2020 ◽  
Vol 9 (6) ◽  
pp. 1917 ◽  
Author(s):  
Kacper Lechowicz ◽  
Sylwester Drożdżal ◽  
Filip Machaj ◽  
Jakub Rosik ◽  
Bartosz Szostak ◽  
...  
Keyword(s):  
Pulmonary Fibrosis ◽  
Age Groups ◽  
Pulmonary Involvement ◽  
World Health ◽  
The Novel ◽  
Wide Range ◽  
The World ◽  
Novel Coronavirus ◽  
Health Organization ◽  
The Right

In December 2019, a novel coronavirus, SARS-CoV-2, appeared, causing a wide range of symptoms, mainly respiratory infection. In March 2020, the World Health Organization (WHO) declared Coronavirus Disease 2019 (COVID-19) a pandemic, therefore the efforts of scientists around the world are focused on finding the right treatment and vaccine for the novel disease. COVID-19 has spread rapidly over several months, affecting patients across all age groups and geographic areas. The disease has a diverse course; patients may range from asymptomatic to those with respiratory failure, complicated by acute respiratory distress syndrome (ARDS). One possible complication of pulmonary involvement in COVID-19 is pulmonary fibrosis, which leads to chronic breathing difficulties, long-term disability and affects patients’ quality of life. There are no specific mechanisms that lead to this phenomenon in COVID-19, but some information arises from previous severe acute respiratory syndrome (SARS) or Middle East respiratory syndrome (MERS) epidemics. The aim of this narrative review is to present the possible causes and pathophysiology of pulmonary fibrosis associated with COVID-19 based on the mechanisms of the immune response, to suggest possible ways of prevention and treatment.

scholarly journals The Placebo Effect on COVID Patients: When the Mind Cures the Body

2021 ◽  
pp. 85-93
Author(s):  
Kirti Mishra
Keyword(s):  
Human Body ◽  
Placebo Effect ◽  
Online Survey ◽  
Human Mind ◽  
The Body ◽  
The Novel ◽  
Placebo Effects ◽  
Novel Coronavirus ◽  
The Right ◽  
The Mind

In this time of novel coronavirus (COVID-19) when everyone is looking for the right treatment and the vaccine a psychological effect can really help make the situation better at homes. There is no doubt in an ideology that the human mind is a compelling tool and so powerful that it is well aware about the concept of placebo effect. It somehow convinces the human body that the placebo medication given in the procedure is equivalent to the proper Medication.  This paper aims to analyses the placebo effect in curing the pain and its role in curing the symptoms of the novel coronavirus (COVID-19) because it is possible that this method may have healed the body of COVID patients. This has been done by considering the related experiments and researches of placebo effect. In this paper conducting the online survey which is help to find the placebo effects on the COVID-19 Patients and taking their opinion towards it and 280 patients for using as a sampling which help to find the approximation of placebo effect on COVID-19 patient. The influences of the placebo effect on the medical business and COVID treatment both have been highlighted. A discussion in futuristic sense about the placebo effect in treatment of COVID-19.

scholarly journals Oral Versus Intravenous Chemotherapy in COVID-19 Epidemic

2021 ◽  
Vol 2 (1) ◽  
pp. 1-4
Author(s):  
Bicheng Wang ◽  
◽  
Boya Xiao ◽  
◽  
Keyword(s):  
Cancer Patients ◽  
Mainland China ◽  
The Novel ◽  
Chemotherapeutic Drugs ◽  
Oral Drugs ◽  
Intravenous Chemotherapy ◽  
Administration Routes ◽  
Intravenous Drugs ◽  
Novel Coronavirus ◽  
The Right

The novel coronavirus has a significant impact on the routine clinical practice for cancer patients in China since December 2019. During the epidemic in mainland China, especially Wuhan, the intravenous chemotherapies of cancer patients were considerably delayed. Up to now, cancer patients throughout the world directly encounter similar obstacles. For patients who have the right to choose chemotherapeutic regimens with different administration routes, oral drugs can be considered to be applied. In this mini-review, oral chemotherapeutic drugs were compared with intravenous drugs in seven types of tumors. Accordingly, we intended to provide useful suggestions for clinicians to balance the benefits and risks of oral against intravenous chemotherapies and to choose properly substituted oral chemotherapeutic regimens for cancer patients amid the coronavirus disease 2019 (COVID-19) pandemic.

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