scholarly journals Oral Versus Intravenous Chemotherapy in COVID-19 Epidemic

2021 ◽  
Vol 2 (1) ◽  
pp. 1-4
Author(s):  
Bicheng Wang ◽  
◽  
Boya Xiao ◽  
◽  
Keyword(s):  
Cancer Patients ◽  
Mainland China ◽  
The Novel ◽  
Chemotherapeutic Drugs ◽  
Oral Drugs ◽  
Intravenous Chemotherapy ◽  
Administration Routes ◽  
Intravenous Drugs ◽  
Novel Coronavirus ◽  
The Right

The novel coronavirus has a significant impact on the routine clinical practice for cancer patients in China since December 2019. During the epidemic in mainland China, especially Wuhan, the intravenous chemotherapies of cancer patients were considerably delayed. Up to now, cancer patients throughout the world directly encounter similar obstacles. For patients who have the right to choose chemotherapeutic regimens with different administration routes, oral drugs can be considered to be applied. In this mini-review, oral chemotherapeutic drugs were compared with intravenous drugs in seven types of tumors. Accordingly, we intended to provide useful suggestions for clinicians to balance the benefits and risks of oral against intravenous chemotherapies and to choose properly substituted oral chemotherapeutic regimens for cancer patients amid the coronavirus disease 2019 (COVID-19) pandemic.

scholarly journals COMPARATIVE ANALYSIS OF COVID-19 EPIDEMIC IN HUBEI PROVINCE AND REST PARTS OF MAINLAND CHINA

2020 ◽  
pp. 1-3
Author(s):  
Youfu Ke ◽  
Zemin Chen ◽  
Bo Peng ◽  
Hoyan Wong ◽  
Yunkeung Wong ◽  
...  
Keyword(s):  
Growth Rates ◽  
Mainland China ◽  
Diagnosis And Treatment ◽  
The Novel ◽  
Fatality Rate ◽  
Treatment Standards ◽  
Daily Observation ◽  
Novel Coronavirus ◽  
Pneumonia Diagnosis ◽  
Close Contacts

Background: China 's national-level anti-COVID-19 campaign has been going on for a month. With the development of the epidemic, it is found that COVID-19 severity in Hubei province (Hubei) is different from the rest of mainland China (Rest of China). It is necessary to compare the two areas, summarize experiences and lessons, analyze the epidemic trend and further point out the direction for the campaign. Methods: Prevent, quarantine and treat the disease according to The Novel Coronavirus Infected Pneumonia Diagnosis and Treatment Standards. Collect the numbers of total close contacts, daily observation cases, daily suspected cases, total conrmed cases, daily severe cases, total deaths from January 20 to February 19, input them into SPSS 25 and Microsoft ofce 2019 excel for data processing, statistical analysis and drawing. Findings: Total conrmed cases in Hubei account for 83.2% of the country. Daily suspected cases growth rates for both areas have become negative since February 9. Daily observation cases in Rest of China reached highest point on February 5 as opposed to February 13 in Hubei, and total close contacts growth rates for the last three days are declining steadily to 1.9% and 3.8% respectively. Total conrmed cases growth rate has hit the lowest levels in Rest of China at 0.34% by comparison with 0.57% in Hubei. Mean fatality rate and mean percentage of severe cases for the last three days in Rest of China are 0.67% and 5.83% in contrast to 3.12% and 18.2% in Hubei. There have been very signicant differences in fatality rate and percentage of severe cases existing in the two areas since January 23 and 24 respectively (P<0.01). Interpretation: Hubei is the main epidemic area. COVID-19 has low fatality rate and high transmissibility. Cutting off the source of infection is pivotal in containing COVID-19 outbreak and has a guiding effect on prevention and control of pandemic worldwide. The Novel Coronavirus Infected Pneumonia Diagnosis and Treatment Standards has played an important role in helping medical staff across the country to ght the epidemic. Coordinating national medical resources to support disaster areas, making full use of the existing facilities to isolate and quarantine, providing timely and accurate treatment can reduce fatality rate. Further efforts are needed to develop highly effective Chinese medicines, western drugs and vaccines in order to eradicate the virus or prevent the epidemic from continuing.

scholarly journals A data-driven assessment of early travel restrictions related to the spreading of the novel COVID-19 within mainland China

2020 ◽  
Author(s):  
Alberto Aleta ◽  
Qitong Hu ◽  
Jiachen Ye ◽  
Peng Ji ◽  
Yamir Moreno
Keyword(s):  
Mainland China ◽  
Behavioral Changes ◽  
The Novel ◽  
Metapopulation Model ◽  
Short Term ◽  
Effective Measure ◽  
Mobility Data ◽  
Health Authorities ◽  
Travel Restrictions ◽  
Novel Coronavirus

Two months after it was firstly reported, the novel coronavirus disease COVID-19 has already spread worldwide. However, the vast majority of reported infections have occurred in China. To assess the effect of early travel restrictions adopted by the health authorities in China, we have implemented an epidemic metapopulation model that is fed with mobility data corresponding to 2019 and 2020. This allows to compare two radically different scenarios, one with no travel restrictions and another in which mobility is reduced by a travel ban. Our findings indicate that i) travel restrictions are an effective measure in the short term, however, ii) they are ineffective when it comes to completely eliminate the disease. The latter is due to the impossibility of removing the risk of seeding the disease to other regions. Our study also highlights the importance of developing more realistic models of behavioral changes when a disease outbreak is unfolding.

scholarly journals The First Case of Reactive Arthritis Associated with SARS-CoV-2-Infection in A 4-Year Old Child

2020 ◽  
Author(s):  
Stephanie Gabriele Werner ◽  
Hans-Eckhard Langer
Keyword(s):  
Severe Acute Respiratory Syndrome ◽  
Reactive Arthritis ◽  
Virus Disease ◽  
The Novel ◽  
Case Presentation ◽  
Corona Virus ◽  
First Case ◽  
Novel Coronavirus ◽  
The Right

Abstract Background: The novel coronavirus SARS‐CoV‐2 (severe acute respiratory syndrome coronavirus 2) and its associated disease COVID‐19 (Corona Virus Disease 19) has become a worldwide pandemic since its first cases in December 2019 in Wuhan Province in China. In Germany the pandemic started in February 2020.Case presentation: A 4 year old boy was presented and suffered from pain in the right hip. Arthrosonography demonstrated a significant effusion in the involved joint. The extended history revealed a slight but long lasting cold before. Serological findings were inconspicuous except for positive ELISA (Enzyme-linked Immuno Sorbent Assay) - test for SARS-CoV-2. Conclusion: In conclusion we believe that we can report the first case of reactive arthritis associated with SARS-CoV-2 in children.

scholarly journals “Door to Treatment” Outcomes of Cancer Patients during the COVID-19 Pandemic

Chemotherapy ◽  
2020 ◽  
pp. 1-6
Author(s):  
Naziye Ak ◽  
Sezai Vatansever
Keyword(s):  
Cancer Patients ◽  
Treatment Time ◽  
Index Case ◽  
Neoadjuvant Treatment ◽  
The Novel ◽  
Newly Diagnosed ◽  
Intravenous Treatment ◽  
Number Of Patients ◽  
Significant Difference ◽  
Novel Coronavirus

<b><i>Background:</i></b> The novel coronavirus disease 2019 has become a worldwide threat. We aimed to explore reflections of these unexpected changes to newly diagnosed cancer patients. <b><i>Method:</i></b> We searched the 2 months after the index case of our country. The first admission day and the first day of intravenous treatment of newly diagnosed patients were recorded. <b><i>Results:</i></b> In the 60 days measured during the pandemic, the total number of patients on polyclinics was 159/weekdays, and the total applied chemotherapy cycles were 276/week. For comparison, the total numbers in the previous year were 267/weekday and 363/week for polyclinic and applied chemotherapy cycles, respectively. The total number of newly admitted patients in 2020 was 283. For comparison, the number of new patients in the same 60-day period in 2019 was 495. Patients who were admitted for adjuvant treatment required a median of 8 days for the first course, those who were admitted for neoadjuvant treatment required 12 days, and metastatic patients required 14 days; there were no significant differences between treatment types (<i>p</i> = 0.233). However, the median treatment time was 11.5 and 17 days, in 2020 and in 2019, respectively. A significant difference was observed between the 2 groups (<i>p</i> &#x3c; 0.001). <b><i>Conclusion:</i></b> The effective shift of workers and accurate regulations have not resulted in apparent delays in patient care. While a decrease in the number of patients has detected, faster healthcare service was introduced to newly diagnosed patients. The reason for the decrease in the number of patients should be investigated with new studies.

scholarly journals Evaluation of the effectiveness of EFL online teaching during the COVID-19 pandemic

SAGE Open ◽  
2021 ◽  
Vol 11 (4) ◽  
pp. 215824402110544
Author(s):  
Bin Zou ◽  
Lulu Huang ◽  
Wulin Ma ◽  
Yuqing Qiu
Keyword(s):  
Online Teaching ◽  
Teaching And Learning ◽  
Mainland China ◽  
The Novel ◽  
Online Teaching And Learning ◽  
University Teachers ◽  
Education Data ◽  
Efl Teaching ◽  
Teachers And Students ◽  
Novel Coronavirus

Online teaching has been massively conducted during the novel coronavirus period all over the world. How to evaluate online teaching has been increasingly researched recently. This study looked at how English as a foreign language (EFL) teaching was delivered online by university teachers during the COVID-19 pandemic. We investigated university teachers and students’ perception of effective EFL online teaching and learning based on several evaluation modes in using technology in education. Data were collected using questionnaires and interviews from teachers and students in a variety of provinces in Mainland China. The results showed that various methods were used to deliver online EFL courses and these approaches are found to correlate with each other. Teachers and students provided positive comments on online teaching and were satisfied with their online teaching and learning. Participants also noted effective ways in online EFL teaching. The findings indicated that when teachers have more training, more skills, and more confidence, they could deliver more effective online teaching and learning.

scholarly journals Lessons from mainland China’s epidemic experience about the growth rules of infected and recovered cases of COVID-19 worldwide

2020 ◽  
Author(s):  
Chuanliang Han ◽  
Yimeng Liu ◽  
Jiting Tang ◽  
Yuyao Zhu ◽  
Carlo Jaeger ◽  
...  
Keyword(s):  
Growth Rate ◽  
Strong Evidence ◽  
Logistic Model ◽  
Mainland China ◽  
Linear Connection ◽  
Control Measures ◽  
Logistic Growth ◽  
Strong Positive Correlation ◽  
The Novel ◽  
Novel Coronavirus

AbstractThe novel coronavirus disease (COVID-19) that emerged at the end of 2019 has been controlled in mainland China so far, while it is still spreading globally. When the pandemic will end is a question of great concern. A logistic model depicting the growth rules of infected and recovered cases in mainland China may shed some light on this question. We extended this model to 31 countries outside China experiencing serious COVID-2019 outbreaks. The model well explained the data in our study (R2 ≥ 0.95). For infected cases, the semi-saturation period (SSP) ranges from 63 to 170 days (March 3 to June 18). The logistic growth rate of infected cases is positively correlated with that of recovered cases, and the same holds for the SSP. According to the linear connection between the growth rules for infected and recovered cases identified from the Chinese data, we predicted that the SSP of the recovered cases outside China ranges from 82 to 196 days (March 22 to July 8). More importantly, we found a strong positive correlation between the SSP of infected cases and the timing of government’s response, providing strong evidence for the effectiveness of rapid epidemic control measures in various countries.

Sign in / Sign up

Export Citation Format

Share Document