To Study the Incidence, Etiology, Laboratory Profile and Risk Factors of Febrile Seizures

2016 ◽  
Vol 4 (3) ◽  
pp. 147-149
Author(s):  
Sunil Mhaske ◽  
◽  
Ninza Rawal ◽  
Liza Bulsara ◽  
◽  
...  
Keyword(s):  
Risk Factors ◽  
Febrile Seizures ◽  
Laboratory Profile

scholarly journals A Study of clinical and laboratory profile of children presenting with febrile seizures in a teaching hospital

2020 ◽  
Vol 8 (1) ◽  
pp. 55-58
Author(s):  
Venkateshwar P
Keyword(s):  
Risk Factors ◽  
Family History ◽  
Incidental Finding ◽  
Hypochromic Anemia ◽  
Febrile Seizures ◽  
Study Group ◽  
History Of ◽  
Laboratory Profile ◽  
History Of Epilepsy ◽  
Sugar Levels

Background: Febrile seizures are the most common cause of convulsions in children. Although most febrile seizures are benign, the child must be evaluated immediately to reduce parental anxiety, to identify the cause of fever and preventable risk factors if any. It is essential to exclude underlying pyogenic meningitis, either clinically or if any doubt remains, by lumbar puncture. The present study evaluated the common risk factors associated with febrile seizures and the conditions causing fever commonly associated with febrile seizures, the morbidity profile and laboratory profile in children presenting with febrile seizures to identify preventable risk factors if any. Methods : n=50 Children in the age group of 6 months to 5 years admitted to the Department of Pediatrics, Prathima Institute of Medical Sciences, Nagunoor, Karimnagar with Febrile Seizures diagnosed as per AAP (American Academy of Pediatrics) guidelines, taken up for the study and compared with 50 other children in the same group with fever but without seizures. Both the study group and control were examined, investigated and compared against each other concerning the clinical and laboratory profile. RESULTS: In the present observational prospective study, the incidence of febrile seizures was more in children less than 24 months of age (78%), with a Male children Preponderance (58%). There were more children with Pallor (70%), Family History of Seizure Disorder (30%), and Consanguinity (38%) in children with Febrile Seizures. URI & Viral fever (44%) were the most common etiological factors for fever among the study group. On investigation, many children with Febrile Seizures had low Haemoglobin levels (60%) and Microcytic Hypochromic blood picture (58%). There was no significant abnormality in Total & Differential Leucocyte Count, Serum Calcium, Electrolyte, Random Blood Sugar levels among the Cases and Controls. Conclusion: Young age (<24 months), family history of febrile seizures and family history of epilepsy are risk factors for febrile seizures. Consanguinity among parents was an incidental finding in children with febrile seizures. Many children with febrile seizures had Microcytic Hypochromic anemia pointing towards iron deficiency thus iron supplementation to prevent anemia may lead to decreased incidence of development and recurrence of febrile seizures. Association of serious infectious diseases with febrile seizures is rare. Laboratory investigations should be directed towards the identification of the cause of fever and not an evaluation of seizure.

The Risk of Seizure Recurrence After a First Unprovoked Afebrile Seizure in Childhood: An Extended Follow-up

PEDIATRICS ◽  
1996 ◽  
Vol 98 (2) ◽  
pp. 216-225 ◽  
Author(s):  
Shlomo Shinnar ◽  
Anne T. Berg ◽  
Solomon L. Moshe ◽  
Christine O'Dell ◽  
Marta Alemany ◽  
...  
Keyword(s):  
Risk Factors ◽  
Age Of Onset ◽  
Multivariable Analysis ◽  
Cumulative Risk ◽  
Febrile Seizures ◽  
Recurrence Risk ◽  
Early Recurrence ◽  
Seizure Recurrence ◽  
Unprovoked Seizure ◽  
History Of

Objective. To assess the long-term recurrence risks after a first unprovoked seizure in childhood. Methods. In a prospective study, 407 children who presented with a first unprovoked seizure were then followed for a mean of 6.3 years from the time of first seizure. Results. One hundred seventy-one children (42%) experienced subsequent seizures. The cumulative risk of seizure recurrence was 29%,37%,42%, and 44% at 1,2,5, and 8 years, respectively. The median time to recurrence was 5.7 months, with 53% of recurrences occurring within 6 months, 69% within 1 year, and 88% within 2 years. Only 5 recurrences (3%) occurred after 5 years. On multivariable analysis, risk factors for seizure recurrence included a remote symptomatic etiology, an abnormal electroencephalogram (EEG), a seizure occurring while asleep, a history of prior febrile seizures, and Todd's paresis. In cryptogenic cases, the risk factors were an abnormal EEG and an initial seizure during sleep. In remote symptomatic cases, risk factors were a history of prior febrile seizures and age of onset younger than 3 years. Risk factors for late recurrences (after 2 years) were etiology, an abnormal EEG, and prior febrile seizures in the overall group and an abnormal EEG in the cryptogenic group. These are similar to the risk factors for early recurrence. Conclusions. The majority of children with a first unprovoked seizure will not have recurrences. Children with cryptogenic first seizures and a normal EEG whose initial seizure occurs while awake have a particularly favorable prognosis, with a 5-year recurrence risk of only 21%. Late recurrences do occur but are uncommon.

scholarly journals Major clinical risk factors for seizures in febrile children aged 6 to 60 months.

2020 ◽  
Vol 27 (05) ◽  
pp. 891-894
Author(s):  
Shahid Ishaq ◽  
Ejaz Mazari ◽  
Fazal ur Rehman
Keyword(s):  
Risk Factors ◽  
Family History ◽  
Febrile Seizures ◽  
Study Groups ◽  
Clinical Risk Factors ◽  
P Value ◽  
Chi Square ◽  
Clinical Risk ◽  
Significant Difference ◽  
History Of

Objectives: Febrile seizures (FS) are the most common type of seizures and typically transpire in children with ages from 6 to 60 months. This study was planned to find out major clinical risk factors for seizures in febrile children who were aged 6 to 60 months. A total of 100 febrile children aged 6 to 60. Study Design: Analytical Study. Setting: Department of Neurology, Children’s Hospital and the Institute of Child Health, Multan. Period: From 1st April 2018 to 31st December 2018. Material & Methods: Group A had 40 children with febrile seizures while group B had 60 febrile children but without seizures. Demographic features along with family history of (H/O) epilepsy as well as family history of febrile seizure, types of seizure and infection diseases were noted and analyzed using SPSS version 20. Odds ratio was calculated for various risk factors. Chi square test was applied and P value < 0.05 was considered as significant. Results: Out of a total of 100 children, there were 54 (54.0%) male and 46 (46.0%) female. There was no statistical difference in terms of gender between the two groups (p value = 0.566). Overall, mean age of the children was 26.02 months with standard deviation of 13.4 months. There were 28 (70.0%) children who reported with simple seizures while complex seizures were found in 12 (30.0%) cases. Statistically significant difference (p value = 0.001) was seen in terms of types of infections between the two study groups. When risk of seizures for various risk factors was calculated, family H/O FS, family H/O epilepsy, and upper RTI were as 14, 7 and 3 times respectively and turned out to be the major risk factors for seizures in febrile children. Conclusions: Family H/O FS, family H/O epilepsy and upper RTIs are the major risk factors related with seizures in febrile children. Measures to prevent these risk factors can decrease the burden of FS in our population.

Antecedents and Risk Factors for Febrile Seizures

2002 ◽  
pp. 27-36 ◽  
Author(s):  
Peter Camfield ◽  
Carol Camfield ◽  
Kevin Gordon
Keyword(s):  
Risk Factors ◽  
Febrile Seizures

Risk factors for febrile seizures in Benghazi, Libya: a case–control study

2017 ◽  
Vol 30 (2) ◽  
pp. 68
Author(s):  
LamiaM Hafez ◽  
AmenhB Yousif ◽  
FatmaS Benkhaial
Keyword(s):  
Risk Factors ◽  
Case Control Study ◽  
Febrile Seizures ◽  
Case Control ◽  
Control Study

Ratios of Nine Risk Factors in Children With Recurrent Febrile Seizures

2010 ◽  
Vol 43 (3) ◽  
pp. 177-182 ◽  
Author(s):  
Ayse Tosun ◽  
Guldane Koturoglu ◽  
Gul Serdaroglu ◽  
Muzaffer Polat ◽  
Zafer Kurugol ◽  
...  
Keyword(s):  
Risk Factors ◽  
Febrile Seizures

scholarly journals Risk factors for subsequent febrile seizures in the FEBSTAT study

Epilepsia ◽  
2016 ◽  
Vol 57 (7) ◽  
pp. 1042-1047 ◽  
Author(s):  
Dale C. Hesdorffer ◽  
Shlomo Shinnar ◽  
Daniel N. Lax ◽  
John M. Pellock ◽  
Douglas R. Nordli ◽  
...  
Keyword(s):  
Risk Factors ◽  
Febrile Seizures

scholarly journals Clinical and laboratory profile and outcome of dengue cases among children attending a tertiary care hospital of South India

2017 ◽  
Vol 4 (3) ◽  
pp. 1074 ◽  
Author(s):  
Punith Patak Nagaram ◽  
Prathima Piduru ◽  
Venkata Krishna Munagala ◽  
Vishnu Vandana Matli
Keyword(s):  
Risk Factors ◽  
Dengue Fever ◽  
Bladder Wall ◽  
Tertiary Care ◽  
Severe Dengue ◽  
Wall Thickening ◽  
Severe Thrombocytopenia ◽  
Care Hospital ◽  
Age Group ◽  
Laboratory Profile

Background: Dengue fever is an arboviral disease which is endemic in tropical countries and is of major concern with its morbidity and mortality. WHO classified dengue into three categories: undifferentiated fever, dengue fever (DF) and dengue haemorrhagic fever (DHF). Severe dengue is also regularly observed during primary infection of infants born to dengue-immune mothers. The objective of present study was to assess the clinical profile, laboratory profile and associated risk factors related to outcome of children less than 15 years of age. The outcome of the children and their management protocols were also assessed in the study.Methods: A prospective cross sectional study with 174 confirmed cases of dengue in children <15 years were enrolled and classified as per WHO guidelines. The demographic data, clinical history, laboratory parameters were noted in a separate questionnaire form. Hematological parameters were noted, chest x-ray, ultra-sonogram in required cases was done and observations noted. Cases were managed as per WHO protocol and risk factors were observed. The outcomes of the cases were noted as discharge or death of the case.Results: A total of 174 children with 149 non-severe dengue and 25 severe dengue cases with 95 males and 79 females were enrolled in the study. 6-10 years was the most common age group. The mean age of children admitted with severe dengue fever was 5.81yrs.and without severe dengue fever was 7yrs.The mean duration of hospitalization was 5.21 days in severe dengue and 3.4 days in non-severe dengue cases. Fever was the most common presenting symptom and hepatomegaly was the common clinical finding in the study.  Bleeding manifestations were seen in cases of severe dengue with raised haematocrit levels, raised SGOT levels and severe thrombocytopenia. Pleural effusion and gall bladder wall thickening with ascites was seen in severe dengue cases. Management was by administration of colloids and crystalloids.Conclusions: Dengue is a dreadful fever among pediatric age group which needs to be considered with great caution in management.  Understanding the risk factors helps in predicting the mortality which helps in management and better outcome of the fever. 

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