scholarly journals Synthesis, spectroscopic and biological studies of some metal complexes with orthoamino hydrazo benzene

2011 ◽  
Vol 8 (2) ◽  
pp. 375-387
Author(s):  
Baghdad Science Journal
Keyword(s):  
Staphylococcus Aureus ◽  
Streptococcus Pyogenes ◽  
Elemental Analysis ◽  
Metal Ion ◽  
Octahedral Geometry ◽  
Conductivity Measurements ◽  
E Coli ◽  
Bivalent Ions ◽  
Biological Studies ◽  
Characteristic Behaviour

Ortho amino hydrazobenzene (L) has been prepared from the reaction of ortho amino phenyl thiol with phenyl hyrazan in mole ratio(1:1). It has been characterized by elemental analysis (C, H, N), IR, UV–Vis. The complexes of the bivalent ions (Co, Ni, Cu, Zn, Pd, Cd, Hg and Pb) and the trivalent (Cr) have been prepared and characterized too. The structural have been established by elemental analysis(C,H,N), IR , UV – Vis spectra , conductivity measurements , atomic absorption and magnetic susceptibility . The complexes showed characteristic behaviour of octahedral geometry around the metal ion and the( N,N) ligand coordinated in bidentate modeexcept with pd showed square planer. ? ,kf , ?max for the complexes were estimated too . ? for Co – complex was calculated . The study of biological activity of the ligand (L) and its complexes showed various activity toward Streptococcus pyogenes Staphylococcus aureus , Pseudomonas aeruginosa , E. coli and Candida albicans .

scholarly journals Synthesis, Characterization and Antibacterial of 2,3-Dihydrobenzo Thiazole-2-Carboxylic Acid Complexes with Some Selected Metal Ions

2015 ◽  
Vol 12 (4) ◽  
pp. 785-796
Author(s):  
Baghdad Science Journal
Keyword(s):  
Magnetic Susceptibility ◽  
Biological Activity ◽  
Carboxylic Acid ◽  
Elemental Analysis ◽  
Octahedral Geometry ◽  
Molar Conductivity ◽  
Dichloroacetic Acid ◽  
E Coli ◽  
Bivalent Ions ◽  
Bidentate Mode

A new ligand 2,3-dihydrobenzo [d] thiazole-2-carboxylic acid (L) has been prepared from the reaction of ortho amino phenyl thiol with dichloroacetic acid in mole ratio (1:1). It has been characterized by elemental analysis (C.H.N.), IR, UV- Vis.spectraand 1H, 13C-NMR. A new series complexes of the bivalent ions (Co, Ni, Cu, Pd, Cd, Hg and Pb) and the trivalent (Cr) have been prepared and characterized too. The structural has been established by elemental analysis (C.H.N.), IR, UV-Vis. spectra, molar conductivity, atomic absorption and magnetic susceptibility measurements. The synthesized complexes were prepared in (1:2) ratio correspond to (Co(II), Ni(II), Cu(II), Pd(II), Cd(II), Hg(II) and Pb(II) complexes while in case Cr(III) complex is (1:1) ratio (M:L). ?, Kf for (Cr(III), Co(II), Ni(II) and Cu(II)) were estimated too. The complexes showed characteristics octahedral geometry with the (O,N) ligand coordinated in bidentate mode except with Pd showed square planer. The study of biological activity of ligand (L) and its complexes showed various activities toward Staphylococcus aureusand E. coli.

Synthesis and Characterization of Some Transition Metal Complexes of Arylidene Salicyloyl and Benzoyl Hydrazones

1984 ◽  
Vol 39 (6) ◽  
pp. 812-816 ◽  
Author(s):  
Y. M. Temerk ◽  
S. A. Ibrahim ◽  
M. M. Kamal
Keyword(s):  
Transition Metal Complexes ◽  
Metal Ion ◽  
Octahedral Geometry ◽  
Molar Conductivity ◽  
Synthesis And Characterization ◽  
Distorted Octahedral Geometry ◽  
Bidentate Ligands ◽  
Conductivity Measurements ◽  
Distorted Octahedral

AbstractComplexes of arylidene salicyloyl- and benzoyl-hydrazones with the 3d metal ions, Cr(III), Mn(II), Fe(III), Co(II), Ni(II) and Cu(II), have been prepared using 2:1 ligand to metal ion ratio. Characterization of the isolated solids was accomplished by IR and electronic spectra, elemental analysis, and molar conductivity measurements. It is concluded that the two Schiff bases function as neutral bidentate ligands and the complexes formed assume a distorted octahedral geometry.

scholarly journals ДОСЛІДЖЕННЯ ПРОТИМІКРОБНИХ ВЛАСТИВОСТЕЙ КОМПОЗИЦІЇ ДЛЯ ЛІКУВАННЯ ЗАПАЛЬНИХ УРАЖЕНЬ ПАРОДОНТУ ВІТЧИЗНЯНОГО ВИРОБНИЦТВА

2021 ◽  
Vol 112 (3) ◽  
pp. 17-24
Author(s):  
О. В. Павленко ◽  
М. В. Кривцова ◽  
О. О. Случевська ◽  
О. М. Ступницька
Keyword(s):  
Escherichia Coli ◽  
Staphylococcus Aureus ◽  
Candida Albicans ◽  
Enterococcus Faecalis ◽  
Streptococcus Pyogenes ◽  
Culture Collection ◽  
American Type Culture Collection ◽  
E Coli

Ціль дослідження. Запально-деструктивні захворю-вання пародонту в світі становлять не тільки зага-льномедичну, а й соціально-економічну проблему, яка спонукає до пошуку нових методів лікування та діаг-ностики. Сучасні концепції лікування хронічного гене-ралізованого пародонтиту передбачають застосу-вання комплексу терапевтичних, ортопедичних, хіру-ргічних і ортодонтичних методів лікування, і доволі часто їх ефективність є сумнівною.На сьогодні загальновизнаним препаратом вибору в пародонтології є хлоргексидину біглюконат (та його інші сполуки), оскільки він здатний пригнічувати ріст і формування колоній понад 80,00% мікроорганізмів біоплівки ротової порожнини.Також у клінічній практиці застосовують протимік-робні препарати системної дії, особливо у випадках агресивних і важких форм генералізованого пародон-титу, що виникають на фоні загальносоматичної патології, а також при ускладненнях хірургічних втручань. Матеріали та методи дослідження. Для проведення досліджень використовували типові музейні культу-ри ATTC (American Type Culture Collection, USA) Candida albicans ATCC 885–653; Staphylococcus aureus ATCC 25923; Escherichia coli ATCC 25922, Enterococcus faecalis ATCC 29212, Streptococcus pyogenes ATCC 19615, та клінічні культури ізольовані із ротової порожнини людей із запальними захворю-ваннями: мікроскопічні гриби роду Candida (C. albicans) Staphylococcus aureus, Escherichia coli, Streptococcus pyogenes, Enterococcus faecalis.Мінімальну бактерицидну та інгібуючу концентрацію досліджуваного гелю визначали у полістиролових пла-стикових 96-лункових планшетах.Результати дослідження та їх обговорення. Ре-зультати дослідження показали, що досліджуваний гель та розчин хлоргексидину біглюконат 0,05% чини-ли активний вплив на музейні та клінічні штами ла-бораторних мікроорганізмів.Висновки. Отже, досліджуваний гель для лікування запальних уражень пародонту вітчизняного виробни-цтва «Джен-Метрогелур» виявився ефективним протимікробним засобом відносно клінічних та лабо-раторних штамів мікроорганізмів. Високочутливими до засобу виявилися клінічні та музейні культури C. albicans. Чутливими до гелю були культури S. aureus та музейні штами S. pyogenes та E. coli. Помірно чу-тливими виявилися культури E. faecalis та клінічні штами S. pyogenes та E. coli.

scholarly journals Synthesis, Characterization and Biological Activity of Mn2+, Co2+, Ni2+and Cu2+Complexes of Benzoic Acid Ligand

2009 ◽  
Vol 6 (3) ◽  
pp. 743-746 ◽  
Author(s):  
T. Arunachalam ◽  
R. Bhakyaraj ◽  
A. K. Sasi
Keyword(s):  
Staphylococcus Aureus ◽  
Pseudomonas Aeruginosa ◽  
Antibacterial Activity ◽  
Magnetic Susceptibility ◽  
Biological Activity ◽  
Benzoic Acid ◽  
Conductivity Measurements ◽  
Octahedral Structure ◽  
E Coli ◽  
Acid Ligand

Metal complex of Mn(II), Co(II), Ni(II) and Cu(II) with benzoic acid have been prepared and characterized by physiochemical methods. On the basis of electronic spectra and magnetic susceptibility measurement in conjunction with infrared spectra, six coordinated octahedral structure have been proposed to all the complexes. The benzoic acid and their complexes have been tested for their antibacterial activity against the bacteriaE. coli,Bacillus subtilis,Pseudomonas aeruginosaandStaphylococcus aureus. Further, the non electrolytic nature of all the synthesized complexes was identified from conductivity measurements.

scholarly journals Synthesis, Spectroscopic Characterization, Molecular Docking, and Evaluation of Antibacterial Potential of Transition Metal Complexes Obtained Using Triazole Chelating Ligand

2020 ◽  
Vol 2020 ◽  
pp. 1-12 ◽  
Author(s):  
Najlaa S. Al-Radadi ◽  
Ehab M. Zayed ◽  
Gehad G. Mohamed ◽  
Hayam A. Abd El Salam
Keyword(s):  
Transition Metal Complexes ◽  
Spectroscopic Characterization ◽  
Octahedral Geometry ◽  
Conductivity Measurements ◽  
Tridentate Ligands ◽  
E Coli ◽  
Triazole Ligand ◽  
Increased Activity ◽  
Antibacterial Potential ◽  
Parent Ligand

Mononuclear chelates of Ni(II), Co(II), Fe(III), Cd(II), and Cu(II) derived from triazole novel tridentate ligands were prepared and characterized by different spectroscopic methods. The metal to ligand ratio was 1 : 2, which was revealed by elemental analysis. All the complexes were electrolytic in nature as suggested by the conductivity measurements. IR pointed out that the coordination of the triazole ligand toward the metal ions was carried out through N amino and S thiophenolic atoms. The complexes were found to have octahedral geometry, and their thermal stability was also studied. The XRD spectrum of Co(II) and Fe(III) complexes concluded their crystalline structure. The parent ligand and its chelates were investigated for antimicrobial potential. Bioassay of all triazole complexes showed increased activity as compared to that of the ligand. The complexes having Ni(II), Co(II), and Cu(II) ions as metal center exhibited superior antibacterial activity in opposition to Gram-positive (B. subtilis and S. pyogenes) and Gram-negative (E. coli and P. vulgaris) bacterium as compared to standard.

scholarly journals Biological Active Cobalt(II) and Nickel(II) Complexes of 12-Membered Hexaaza [N6] Macrocyclic Ligand Synthetic and Spectroscopic Aspects

2010 ◽  
Vol 7 (4) ◽  
pp. 1238-1245 ◽  
Author(s):  
Umendra Kumar ◽  
Sulekh Chandra
Keyword(s):  
Thermal Analysis ◽  
Magnetic Susceptibility ◽  
Metal Ion ◽  
Macrocyclic Ligand ◽  
Pathogenic Fungi ◽  
Spectroscopic Studies ◽  
Molar Conductance ◽  
Octahedral Geometry ◽  
Conductivity Measurements ◽  
Macrocyclic Schiff Base

New cobalt(II) and nickel(II) complexes of 12-membered macrocyclic Schiff - base ligand containing thiosemicarbazone moiety as a part of ring have been prepared having general composition [MLX2] where M = Co(II) or Ni(II), L=3,4,9,10–tetra-2-furanyl-1,2,5,6,8,11- hexaazacyclododeca-7,12- dithione - 2,4,8,10 – tetraene, X = Cl-, NO3-, NCS-. The complexes have been characterized by elemental analysis, molar conductance, magnetic susceptibility measurements, spectral (IR, electronic, EPR) techniques and thermal analysis. Spectroscopic studies suggested a six coordinated octahedral geometry for all the complexes. The IR spectra of complexes suggest that ligand is coordinated to the metal ion through its four imines nitrogen. Conductivity measurements supported the non electrolytic nature of the complexes. The antifungal activities of complexes have been studied against a number of pathogenic fungi under laboratory conditions. The complexes showed good antifungal results. Thermal analysis of reported complexes suggests the absence of water molecule either in or outside the coordination sphere.

scholarly journals Cu(II), Mn(II), Ni(II) Complexes of Mixed Amodiaquine and Paraaminobenzoic acid: Synthesis, Characterization, Antimicrobial and Toxicological Activities in Wister rats

2020 ◽  
Vol 25 (4) ◽  
pp. 7-20
Author(s):  
Mercy Bamigboye ◽  
Ikechukwu P. Ejidike ◽  
Abdulbasit A. Aliyu
Keyword(s):  
Metal Ion ◽  
Acid Synthesis ◽  
Antimicrobial Activities ◽  
Octahedral Geometry ◽  
The Body ◽  
Spectroscopic Techniques ◽  
Zone Of Inhibition ◽  
E Coli ◽  
Paraaminobenzoic Acid ◽  
Acid Produce

Four novel metal complexes of mixed amodiaquine and paraaminobenzoic acid have been synthesized using a standard method and confirmed by results of some physicochemical and spectroscopic techniques. Antimicrobial activities have been carried out on the complexes against some selected organisms: (antibacterial organisms: K. pneumonia, B. subtilis, E. coli, S. aureus, P. aeruginosa and S. faecalis) and (antifungal organisms: Candida albicans, Aspergillus niger and Penicillium chrysogenum) to determine their effectiveness. The complexes were evaluated for their toxicity level in wister rats. The Amodiaquine and Paraaminobenzoic acid produce complexes in ratio 1:1:1 in coordination with the metal ion. Octahedral geometry has been proposed for all the complexes. The complexes were found to be non-electrolytic in nature. The complexes were observed to be more active than their free ligands as determined by their zone of inhibition (nm). The complexes have been proved to be less toxic to the body.

scholarly journals Metal ion promoted synthesis of pentaazamacrocyclic complexes of a few first row transition metal series derived from 2,6-diaminopyridine

2005 ◽  
Vol 70 (11) ◽  
pp. 1273-1281
Author(s):  
Ali Khan ◽  
Shabana Tabassum ◽  
Nishat Begum ◽  
Poonam Chingsubam
Keyword(s):  
Magnetic Susceptibility ◽  
Transition Metal ◽  
1H Nmr ◽  
Elemental Analysis ◽  
Metal Ion ◽  
Condensation Reaction ◽  
Spectroscopic Techniques ◽  
Conductivity Measurements ◽  
Template Condensation ◽  
Square Planar

Anew series of dichloro/dinitrato (2,6,9,13,18-pentaazacbicyclo [12.3.1]octadeca -1(18),14,16-triene) metal(II) [MLX2](M = Mn(II), Co(II), Ni(II) and Zn(II); X = Cl or NO3) and (2,6,9,13,18-pentaazacyclo[12.3.1]octadeca-1(18),14,16-triene) copper(II) dichloride/dinitrate [CuL]X2 (X = Cl or NO3) have been synthesized by the template condensation reaction of 2,6-diaminopyridine with 1,2-diaminoethane and 1,3-dibromopropane. The complexes were studied by elemental analysis, magnetic susceptibility and conductivity measurements. Various spectroscopic techniques, viz. IR, 1H-NMR, EPR, UV/Vis, were used to establish their structures. Except for the complexes of copper(II), which are square planar, all other complexes have octahedral structures.

Divalent Transition Metal Complexes of Potentially Polynucleating 8-Hydroxyquinoline-5-sulfonyl Hydrazone

1994 ◽  
Vol 59 (8) ◽  
pp. 1800-1808
Author(s):  
Said A. Ibrahim ◽  
Sahar A. El-Gyar ◽  
Aly A. Abdel-Hafez ◽  
Mostafa K. Rabia
Keyword(s):  
Antimicrobial Activity ◽  
Nmr Spectroscopy ◽  
Transition Metal Complexes ◽  
Elemental Analysis ◽  
Metal Ion ◽  
Free Ligand ◽  
Chelating Agent ◽  
Conductivity Measurements ◽  
H Nmr ◽  
Trinuclear Complexes

The Co(II), Ni(II), Cu(II) and Zn(II) complexes with 8-hydroxyquinoline-5-sulfonylhydrazone are described. It has been found that the ligand can coordinate to metal ion as a monobasic bidentate chelating agent and it can form di- and trinuclear complexes while acting as a dibasic tetradentate one. The structure of the isolated complexes have been suggested on the basis of elemental analysis, IR, 1H NMR spectroscopy and conductivity measurements. The complexes are all formulated as four-coordinate. Some complexes showed enhanced antimicrobial activity relative to the free ligand.

scholarly journals Synthesis, Characterization and Antimicrobial Activity of Mixed-Ligand Complexes of Cu(II) with 1,2,4, Triazole and Amino Acids

2014 ◽  
Vol 6 (3) ◽  
pp. 487-496
Author(s):  
B. Anupama ◽  
C. G. Kumari
Keyword(s):  
Amino Acids ◽  
Antimicrobial Activity ◽  
Molecular Modeling ◽  
Elemental Analysis ◽  
Metal Ion ◽  
Ternary Complexes ◽  
Mixed Ligand ◽  
Conductivity Measurements ◽  
Tetrahedral Geometry ◽  
Molecular Modeling Studies

Mixed-ligand ternary complexes of Cu (II) metal ion with 1,2,4 triazole (TRZ) and amino acids (histidine (L1), threonine (L2), proline (L3) and hydroxyl proline (L4)) have been synthesized. The prepared ternary chelates were characterized by elemental analysis, IR and electronic spectra, as well as conductivity measurements. The general formula [Cu(TRZ)L]H2O were found for the ternary chelates containing TRZ. From the analytical and spectral data, the stoichiometry has been found to be 1:1:1 for all the complexes. A tetrahedral geometry has been proposed. Molecular modeling studies were also carried out to confirm the geometries of the complexes. All the new complexes were found to be active against bacteria. © 2014 JSR Publications. ISSN: 2070-0237 (Print); 2070-0245 (Online). All rights reserved. doi: http://dx.doi.org/10.3329/jsr.v6i3.16993 J. Sci. Res. 6 (3), 487-496 (2014)

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