scholarly journals The Age of Natural Menopause and Related Factors among the Population of the Tabari Cohort.

2019 ◽  
Author(s):  
Marzieh Zamaniyan ◽  
Mahmood Moosazadeh ◽  
Sepideh Peyvandi ◽  
Kaveh Jaefari ◽  
Reza Goudarzi ◽  
...  
Keyword(s):  
Cohort Study ◽  
Population Based ◽  
Breastfeeding Duration ◽  
Chi Square ◽  
Related Factors ◽  
Natural Menopause ◽  
Blood Samples ◽  
Related Data ◽  
Confounding Variables ◽  
The Mean

Abstract Background: Age of menopause is affected by several factors. In this study we aimed to identify the age of natural menopause and its related factors in a large-scaled population-based cohort study in Iran. Methods: In this study, we utilized a subset of data collected in enrollment phase of Tabari cohort study (TCS). Reproductive history and other related data were collected using structural questionnaire. Blood samples were collected form all participants. We analyzed data using chi-square, independent t-test and ANOVA as well as multivariate linear regression model. Results: Among all participants of Tabari cohort, 2753 were menopause women. The mean age of natural and induced menopause was 49.2±4.7 and 43.2 ± 6.4 respectively (P = 0.001). Our finding showed that number of pregnancy, breastfeeding duration, education, residency, thyroid disease and body mass index affect age of menopause. After adjustment for confounding variables, number of pregnancy remained significantly associated with late menopause. Conclusion: Results of the present study showed that number of pregnancy was positively associated with menopausal age.

scholarly journals End-Of-Life Discussions Reduce The Utilization of Life-Sustaining Treatments During The Last Three Months of Life in Cancer Patients : A Nationwide Population-Based Cohort Study

2021 ◽  
Author(s):  
Shang-Yih Chan ◽  
Yun-Ju Lai ◽  
Yu-Yen Hsin Chen ◽  
Shuo-Ju Chiang ◽  
Yi-Fan Tsai ◽  
...  
Keyword(s):  
Cohort Study ◽  
Cardiopulmonary Resuscitation ◽  
End Of Life ◽  
Cancer Patients ◽  
Medical Records ◽  
Population Based ◽  
Lower Likelihood ◽  
The Mean ◽  
The Impact ◽  
To Receive

Abstract Purpose Studies to examine the impact of end-of-life (EOL) discussions on the utilization of life-sustaining treatments near death were limited and had inconsistent findings. This nationwide population-based cohort study determined the impact of EOL discussions on the utilization of life-sustaining treatments in the last three months of life in Taiwanese cancer patients. Methods This cohort study included adult cancer patients from 2012–2018, which were confirmed by pathohistological reports. Life-sustaining treatments during the last three months of life included cardiopulmonary resuscitation, intubation, and defibrillation. EOL discussions in cancer patients were confirmed by their medical records. Association of EOL discussions with utilization of life-sustaining treatments were assessed using multiple logistic regression. Results Of 381,207 patients, the mean age was 70.5 years and 19.4% of the subjects utilized life-sustaining treatments during the last three months of life. After adjusting for other covariates, those who underwent EOL discussions were less likely to receive life-sustaining treatments during the last three months of life compared to those who did not (Adjusted odds ratio [AOR]: 0.82; 95% confidence interval [CI]: 0.80–0.84). Considering the type of treatments, EOL discussions correlated with a lower likelihood of receiving cardiopulmonary resuscitation (AOR = 0.43, 95% CI: 0.41–0.45), endotracheal intubation (AOR = 0.87, 95%CI: 0.85–0.89), and defibrillation (AOR = 0.52, 95%CI: 0.48–0.57). Conclusion EOL discussions correlated with a lower utilization of life-sustaining treatments during the last three months of life among cancer patients. Our study supports the importance of providing these discussions to cancer patients to better align care with preferences during the EOL treatment.

Correlates of Age at Natural Menopause in the Cohorts of Epic-Italy

2003 ◽  
Vol 89 (6) ◽  
pp. 608-614 ◽  
Author(s):  
Egidio Celentano ◽  
Rocco Galasso ◽  
Franco Berrino ◽  
Elisabetta Fusconi ◽  
Maria Concetta Giurdanella ◽  
...  
Keyword(s):  
Cigarette Smoking ◽  
Life Style ◽  
Ovarian Function ◽  
Age Of Onset ◽  
Large Population ◽  
Population Based ◽  
Added Value ◽  
Scientific Interest ◽  
Related Factors ◽  
Natural Menopause

A large number of studies have investigated the factors correlated to age at natural menopause in several populations. However, information on genetics and life-style factors influencing the age of onset of menopause in different populations is of current scientific interest. Specifically, for Italian women there are no large population-based data. The EPIC-Italy collaboration is a source of data of this kind; moreover, the geographical distribution of the cohorts (recruited in northern, central and southern Italy) is an added value as regards the scientific interest of these data. A number of biological and life-style-related factors have been analyzed to evaluate their association to the age at natural menopause in 14,454 menopausal women of the EPIC-Italy collaboration. As regards life-style and environmental factors, the main results are: a) women living in different areas of the country have different ages of onset of natural menopause; b) educational level is significantly associated to this age and may explain part of the between-center difference; c) cigarette smoking appears as a major correlate and probably determinant of the age at natural menopause across all the Italian cohorts; d) alcohol consumption does not have any relationship with the age at natural menopause; e) the use of oral contraceptives may influence age at natural menopause. As regards biological factors, short cycles and low parity have been found associated with earlier menopause. Overall, the results concerning menstrual cycles, parity, and cigarette smoking are consistent with the hypothesis that the number of oocytes in the ovary is pre-determined and any acceleration or impairment of the ovarian function leads to reduce the duration of the reproductive life.

scholarly journals Sleep Quality and Its Associated Factors among Low-Income Adults in a Rural Area of China: A Population-Based Study

2018 ◽  
Vol 15 (9) ◽  
pp. 2055 ◽  
Author(s):  
Wenwen Wu ◽  
Wenru Wang ◽  
Zhuangzhuang Dong ◽  
Yaofei Xie ◽  
Yaohua Gu ◽  
...  
Keyword(s):  
Sleep Quality ◽  
Low Income ◽  
Rural Areas ◽  
Population Based ◽  
Poor Sleep ◽  
Chinese Adults ◽  
Poor Sleep Quality ◽  
Related Factors ◽  
Health Related ◽  
The Mean

Background: There is limited population-based research focusing on sleep quality among low-income Chinese adults in rural areas. This study aimed to assess sleep quality among low-income adults in a rural area in China and identify the association between sleep quality and sociodemographic, lifestyle and health-related factors. Methods: The study was conducted from September to November in 2017 using a cross-sectional survey questionnaire. A total of 6905 participants were recruited via multistage, stratified cluster sampling. Data were collected using the Chinese versions of Pittsburgh Sleep Quality Index and Food Frequency Questionnaire, while we also determined the sociodemographic profiles of the participants. Results: The mean age of the sample was 58.71 ± 14.50 years, with 59.7% being male, while the mean duration of daily sleep was 5.95 ± 1.31 h, with 56.7% reportedly experiencing poor sleep quality. Multiple regression analysis revealed that older age, unemployment, lower income, disability and chronic disease comorbidities were significant factors associated with an increased risk of poor sleep quality for both genders. Moreover, married and higher education level were associated with decreased risk of poor sleep quality for females, while a meat-heavy diet and illness during the past two weeks increased the risk of poor sleep quality for males. Conclusions: Sociodemographic, lifestyle and health-related factors had an impact on the frequently poor sleep quality of low-income Chinese adults in rural areas. Thus, comprehensive measures must be developed to address the modifiable predictive factors that can possibly enhance sleep quality.

scholarly journals Population-based cohort study examining the association between splenectomy and empyema in adults in Taiwan

BMJ Open ◽  
2017 ◽  
Vol 7 (9) ◽  
pp. e015101 ◽  
Author(s):  
Hsien-Feng Lin ◽  
Kuan-Fu Liao ◽  
Ching-Mei Chang ◽  
Cheng-Li Lin ◽  
Shih-Wei Lai
Keyword(s):  
Cohort Study ◽  
Incidence Rate ◽  
Proportional Hazards ◽  
Population Based ◽  
Cox Proportional Hazards ◽  
Proportional Hazards Regression ◽  
Kaplan Meier ◽  
Confounding Variables ◽  
Taiwan National Health Insurance

ObjectiveThis study aimed to investigate the association between splenectomy and empyema in Taiwan.MethodsA population-based cohort study was conducted using the hospitalisation dataset of the Taiwan National Health Insurance Program. A total of 13 193 subjects aged 20–84 years who were newly diagnosed with splenectomy from 2000 to 2010 were enrolled in the splenectomy group and 52 464 randomly selected subjects without splenectomy were enrolled in the non-splenectomy group. Both groups were matched by sex, age, comorbidities and the index year of undergoing splenectomy. The incidence of empyema at the end of 2011 was calculated. A multivariable Cox proportional hazards regression model was used to estimate the HR with 95% CI of empyema associated with splenectomy and other comorbidities.ResultsThe overall incidence rate of empyema was 2.56-fold higher in the splenectomy group than in the non-splenectomy group (8.85 vs 3.46 per 1000 person-years). The Kaplan-Meier analysis revealed a higher cumulative incidence of empyema in the splenectomy group than in the non-splenectomy group (6.99% vs 3.37% at the end of follow-up). After adjusting for confounding variables, the adjusted HR of empyema was 2.89 for the splenectomy group compared with that for the non-splenectomy group. Further analysis revealed that HR of empyema was 4.52 for subjects with splenectomy alone.ConclusionThe incidence rate ratio between the splenectomy and non-splenectomy groups reduced from 2.87 in the first 5 years of follow-up to 1.73 in the period following the 5 years. Future studies are required to confirm whether a longer follow-up period would further reduce this average ratio. For the splenectomy group, the overall HR of developing empyema was 2.89 after adjusting for age, sex and comorbidities, which was identified from previous literature. The risk of empyema following splenectomy remains high despite the absence of these comorbidities.

Abstract 017: Meal Intervals And Weight Trajectories In Adults Using The Daily24 Mobile Application: A Prospective Cohort Study

Circulation ◽  
2021 ◽  
Vol 143 (Suppl_1) ◽  
Author(s):  
Di Zhao ◽  
Thomas Woolf ◽  
Lindsay Martin ◽  
Eliseo Guallar ◽  
Harold Lehmann ◽  
...  
Keyword(s):  
Cohort Study ◽  
Prospective Cohort Study ◽  
Weight Change ◽  
Prospective Cohort ◽  
Mobile Application ◽  
Population Based ◽  
Randomized Controlled Studies ◽  
The Mean ◽  
Weight Decrease ◽  
Weight Trajectories

Background: Small pilot and randomized controlled studies suggest that time-restricted feeding may decrease body weight. However, the role of meal timing and intervals, measured using mobile applications, has not been examined in larger population-based studies. The objective of this study is to evaluate the association between meal intervals and weight trajectories among adults from a population-based clinical cohort. Methods: Multi-site prospective cohort study of adults recruited from three health systems. Over the 6-month study period, 547 participants downloaded and used the Daily24 mobile application to record the timing of meals and sleep for at least one day. Intervals were calculated as the average of all available daily entries for each participant. We obtained information on weight and comorbidities at each outpatient visit from electronic health records available for up to 10 years prior to until 10 months after baseline. We used mixed linear regression to model weight trajectories. Results: The mean (SD) baseline (at consent) age was 51.1 (15.0) years and body mass index (BMI) 30.8 (7.8) kg/m 2 ; 77.9% were women and 77.5% were White. Average time in the cohort was 5.9 years prior to and 0.3 years after baseline. The mean interval from first to last meal was 11.5 (2.3) hours. The associations between meal intervals and weight trajectories are shown in the Table . The number of meals per day was positively associated with weight change before baseline, and number of snacks and drinks per day was inversely associated with weight change after baseline. Each additional occasion of snacks and drinks was associated with a 3.20 kg weight decrease (95% CI 1.41 to 4.99). None of the other associations were statistically significant. Conclusions: Number of daily meals was positively associated with weight change in previous periods, while the number of daily snacks and drinks was inversely associated with weight trajectory. The intervals from first to last meal was not associated with weight change.

Age at natural menopause in women with a history of chronic diseases: A population-based cohort study

Maturitas ◽  
2021 ◽  
Author(s):  
Mina Amiri ◽  
Maryam Rahmati ◽  
Maryam Farahmand ◽  
Fereidoun Azizi ◽  
Fahimeh Ramezani Tehrani
Keyword(s):  
Cohort Study ◽  
Chronic Diseases ◽  
Population Based ◽  
Natural Menopause ◽  
History Of

scholarly journals Looking beyond the mean in grief trajectories: A prospective, population-based cohort study

2019 ◽  
Vol 232 ◽  
pp. 460-469 ◽  
Author(s):  
Mette Kjærgaard Nielsen ◽  
Anders Helles Carlsen ◽  
Mette Asbjoern Neergaard ◽  
Pernille Envold Bidstrup ◽  
Mai-Britt Guldin
Keyword(s):  
Cohort Study ◽  
Population Based ◽  
The Mean

scholarly journals Prospectively Measured Levels of Serum Follicle-Stimulating Hormone, Estradiol, and the Dimeric Inhibins during the Menopausal Transition in a Population-Based Cohort of Women1

1999 ◽  
Vol 84 (11) ◽  
pp. 4025-4030 ◽  
Author(s):  
Henry G. Burger ◽  
Emma C. Dudley ◽  
John L. Hopper ◽  
Nigel Groome ◽  
Janet R. Guthrie ◽  
...  
Keyword(s):  
Menopausal Status ◽  
Population Based ◽  
Logistic Function ◽  
Natural Menopause ◽  
Hormone Levels ◽  
Before And After ◽  
Individual Woman ◽  
The Mean ◽  
Almost All ◽  
Hormonal Levels

The aims of this study were: 1) to describe, in relation to the date of final menses, the average hormone levels of women in the years before and after this date and to determine the extent to which these average levels were dependent on age and body mass index (BMI); and 2) to determine the degree of tracking in residual hormone levels[ i.e., the extent to which individuals above (below) the mean for their age or time relative to final menstrual period (FMP) and BMI remain above (below) the mean as time progresses]. Serial levels of serum FSH, circulating estradiol (E2), and the dimeric inhibins (INH) A and B were measured annually in 150 women who experienced a natural menopause during 6 years of follow-up. Means of the log-transformed hormonal levels were analyzed as a double-logistic function of time relative to FMP, as well as age and BMI and correlations between repeated hormonal levels, were measured. Mean FSH levels started to increase from about 2 years before the FMP, increased most rapidly about 10 months before the FMP, and had virtually plateaued by 2 years after the FMP. FSH levels were, on average, 3% greater for each year of age and 2% lower for each kg/m2 of BMI. After adjusting for time relative to the FMP, logFSH showed modest tracking. Age-adjusted values of logFSH were moderately correlated across time, and much of this tracking was explained by the actual timing of a woman’s FMP. Mean E2 levels started to decrease about 2 years before the FMP, decreased most rapidly around the time of the FMP, and had virtually plateaued by 2 years after the FMP. E2 levels were lower, on average, by about 9% per year of age, and residual values showed weak tracking. Levels of both INHA and INHB decreased, on average, in the years before the FMP and were undetectable (INHA, <10 pg/mL; INHB, < 25 pg/mL) in the majority of women by the time of the FMP and in almost all women by 4 years post-FMP. Significant negative correlations between log serum FSH and log E2 (r = −0.73) and log INHA (r = −0.41) and log INHB (r = −0.36) were observed. It is concluded that substantial changes in reproductive hormone levels occur within 1–2 yr on each side of the FMP, that falling concentrations of E2 and the INH contribute to the rising concentrations of FSH, and that there is no single reliable hormonal marker of menopausal status for an individual woman.

scholarly journals KNOWLEDGE, ATTITUDE, AND PRACTICE ON DIABETIC FUNDUS EXAMINATION AMONG GENERAL PRACTITIONERS IN PUSKESMAS OF BANDUNG CITY

2021 ◽  
Vol 4 (1) ◽  
Author(s):  
Nina Ratnaningsih
Keyword(s):  
Diabetic Retinopathy ◽  
Population Based ◽  
Cross Sectional Study ◽  
P Value ◽  
Fundus Examination ◽  
Eligibility Criteria ◽  
Chi Square ◽  
Related Factors ◽  
Cross Sectional ◽  
Knowledge And Attitude

Introduction: The prevalence of Diabetic Retinopathy (DR) and Vision Threatening Diabetic Retinopathy (VTDR) in Greater Bandung on 2017 was 24,7% and 9% respectively. It mean almost 30% DR fall into VTDR, although it could be prevented. Fundus examination in primary level of prevention is important to prevent VTDR, and potential barriers on it included knowledge, attitude, practice and related factors should be overcome. The objective of this research was to assess knowledge, attitude, practice (KAP) and related factors on diabetic fundus examination among GPs in Puskesmas of Bandung City. Method: This was a population based cross sectional study conducted on April-June 2020, involving 115 GPs at 62 Puskesmas of Bandung City who fulfilled the eligibility criteria by purposive sampling. It used self administered KAP questionnaire on diabetic fundus examination. The data were presented in descriptive and analytical explanation using Chi-square with p value of 0,05 as statistical significant result . Result: The mean of knowledge and attitude on fundus examination were 70,67 (95% CI ± 3,26), 72,87 (95% CI ± 2,61) respectly, included in good criteria, but Practice was poor for 95,65% participants. Poor practice was associated significantly with no availability of direct ophthalmoscope (p= 0.00038) that can not be accessed by 98 of participants (85%).Other GPs with ophthalmoscope access still did not conduct fundus examination because of no mydriasis to dilate pupil. Conclusion: Knowledge and attitude on fundus examination among GPs was good, but poor for practice. It was associated with direct ophthalmoscope and mydriasis availability. It need advocation approach to overcome.

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