Risk factors of tractional retinal detachment in non-silicone oil tamponade eyes after vitrectomy for proliferative diabetic retinopathy
Abstract BackgroundTraction retinal detachment is one of the serious complications of proliferative diabetic retinopathy (PDR) and poses a serious threat to the visual acuity of patients.The purpose of this paper is to investigated the risk factors of tractional retinal detachment (TRD) in non-silicone oil tamponade eyes after vitrectomy for PDR.MethodsWe performed a retrospective review of patients with postoperative TRD who underwent vitrectomy with non -silicone oil tamponade (C3F8, sterilized air or BSS) for PDR. The clinical information, including laboratory tests and the history of ocular treatment, was determined and compared to the control group to analyze their significance.ResultsThe control group consisted of 28 patients who underwent vitrectomy with non-silicone oil tamponade for PDR immediately one proceeding and one following the surgery of each of the 14 patients (TRD group) with postoperative TRD. The history of photocoagulation, serum albumin, blood urea nitrogen and serum creatinine were significantly associated with TRD. The logistic regression analysis indicated that lower serum albumin concentration was the major systemic risk factor for the occurrence of TRD (P = 0.027).ConclusionThe main systemic risk factor related to TRD was serum albumin in patients with PDR who underwent vitrectomy with non-silicone oil tamponade. Preoperative albumin supplementation may reduce the risk of postoperative TRD.