scholarly journals Associations Of Abnormalities Detected On Mri And Radiography With Hand Pain And Function In A Population-Based Older Adult Cohort.

2020 ◽  
Author(s):  
Siti Maisarah Mattap ◽  
Karen Wills ◽  
Dawn Aitken ◽  
Andrew Halliday ◽  
Shi-Nan Luong ◽  
...  
Keyword(s):  
Grip Strength ◽  
Joint Space ◽  
Population Based ◽  
Hand Osteoarthritis ◽  
Imaging Features ◽  
Cross Sectional ◽  
X Ray ◽  
Hand Pain ◽  
Pain Scores ◽  
And Function

Abstract Objective To describe associations between hand abnormalities on MRI or radiographs (X-ray) and pain and function in a cross-sectional study of community-based older adults. Methods Distal and proximal interphalangeal index finger joints (n=221) were examined using MRI, X-ray, and hand examination. Hand pain, function, and stiffness were assessed using Australian/Canadian hand osteoarthritis index (AUSCAN) questionnaire. Grip strength was assessed using dynamometer. Models were adjusted for age, sex, and other MRI or X-ray abnormalities. Results Absence of collateral ligament (CLs) on MRI (relative risk; RR=3.15 (95% confidence interval 1.33, 7.50), and joint space narrowing (JSN) on X-ray (RR=2.96 (1.33, 6.58)) was associated with having a painful joint after adjustment for confounders. JSN was also associated with tender joints (RR=2.19 (1.01, 4.76)). Effusion-synovitis was associated with better AUSCAN pain scores (OR=0.51 (0.28, 0.94)) and JSN with worse AUSCAN pain scores (odds ratio; OR=1.67 (1.13, 2.48)). Absent CLs were also associated with stiffer joints (OR=3.12 (1.26, 7.70)) and weaker grip strength (β=-1.69 (-2.95, -0.43)) independent of pain and other features; JSN was also associated with weaker grip strength (β=-0.87 (-1.62, -0.14)). No other MRI or X-ray abnormalities were associated with pain or function independent of age, sex or pain. Conclusion Most MRI abnormalities were not associated with pain and function cross-sectionally. Absent CLs and JSN were associated with painful joints and weak grip strength independent of pain and other imaging features. JSN was also associated with tender joints and absent CLs with stiff joints. Unexpectedly, effusions were associated with reduced odds of pain.

scholarly journals Initial stages of hand osteoarthritis do not affect the extrinsic muscles of the hand: a cross-sectional study

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Natália Barbosa Tossini ◽  
André Luis Simões Zacharias ◽  
Luiza Souza Seraphim Abrantes ◽  
Paula Regina Mendes da Silva Serrão
Keyword(s):  
Grip Strength ◽  
Handgrip Strength ◽  
Hand Function ◽  
Initial Assessment ◽  
Control Group ◽  
Hand Osteoarthritis ◽  
Strong Negative Correlation ◽  
Cross Sectional ◽  
Extensor Torque ◽  
And Function

AbstractThe objective of this study was to verify whether women in the initial stages of hand osteoarthritis (HOA) already have impaired grip strength and flexor and extensor torque of the wrist compared to healthy women. It also aimed to correlate these variables with pain, stiffness, and function of the hand. Twenty-six women were divided into a control group [CG, n = 13; 56 (51–61) years old] and a hand osteoarthritis group [HOAG, n = 13; 58 (53–63) years old]. Grades II and III were included in the HOA group according to the criteria of Kellgren and Lawrence. All volunteers answered an initial assessment form, the Disabilities of the Arm, Shoulder, and Hand (DASH) questionnaire and the Australian/Canadian Hand Osteoarthritis Index (AUSCAN). The grip strength and isometric wrist flexor and extensor torque were evaluated by a hydraulic dynamometer. Comparisons between groups used Student’s t test for independent samples and the Mann–Whitney test. Spearman's correlation was used to correlate grip strength and flexor and extensor wrist torque to the degree of disease and DASH and AUSCAN scores. There were no differences between the groups in grip strength or flexor and extensor torque values. In terms of the DASH and the AUSCAN, the HOA group had higher scores, indicating worse hand function. A strong negative correlation was found between grip strength and the degree of HOA (r =  − 0.70, p = 0.008), and a moderate positive correlation was found between flexor torque and the degree of HOA (r = 0.53, p = 0.05). The pain (r =  − 0.61, p = 0.02) and function (r =  − 0.66, p = 0.01) sections of the AUSCAN correlated negatively with grip strength. Pain can be an important feature in the HOA rehabilitation process, as it can influence handgrip strength and function. It is important that rehabilitation is implemented as soon as possible to guarantee the maintenance of strength and function since with the severity of the disease, patients tend to have deficits in grip strength and function.

scholarly journals Diurnal Salivary Cortisol in Sarcopenic Postmenopausal Women: The OsteoLaus Cohort

2021 ◽  
Author(s):  
Elena Gonzalez Rodriguez ◽  
Pedro Marques-Vidal ◽  
Bérengère Aubry-Rozier ◽  
Georgios Papadakis ◽  
Martin Preisig ◽  
...  
Keyword(s):  
Postmenopausal Women ◽  
Salivary Cortisol ◽  
Population Based ◽  
Cross Sectional Study ◽  
Body Composition Assessment ◽  
Cross Sectional ◽  
X Ray ◽  
Free Cortisol ◽  
Cortisol Levels ◽  
The Relationship

AbstractSarcopenia, similar to hypercortisolism, is characterized by loss of muscle mass and strength. Cortisol circadian rhythm changes with aging (blunted late-day nadir values) were suggested to contribute to this decline. We aimed to explore the relationship between diurnal salivary cortisol values and sarcopenia diagnosis and its components in postmenopausal women. This is a cross-sectional study within the OsteoLaus population-based cohort in Lausanne (Switzerland). Participants had a body composition assessment by dual X-ray absorptiometry (DXA), a grip strength (GS) measure, and salivary cortisol measures (at awakening, 30 min thereafter, 11 AM (sc-11AM) and 8 PM (sc-8PM)). Associations between salivary cortisol and sarcopenia diagnosed by six different criteria (based on appendicular lean mass (ALM) assessed by DXA, and muscle strength by GS), and its components, were analyzed. 471 women aged > 50 years (63.0 ± 7.5) were included. Various definitions identified different participants as sarcopenic, who consistently presented higher salivary cortisol at 11 AM and/or 8 PM. There were no associations between salivary cortisol levels and ALM measures, either absolute or after correction to height squared (ALM index) or body mass index. GS was inversely correlated to sc-11AM (r = − 0.153, p < 0.001) and sc-8PM (r = − 0.118, p = 0.002). Each 10 nmol/l increase of sc-11AM, respectively sc-8PM, was associated with a GS decrease of 1.758 (SE 0.472) kg, respectively 2.929 (SE 1.115) kg. In postmenopausal women, sarcopenia is associated with higher salivary cortisol levels at 11 AM and 8 PM. An increase of daily free cortisol levels in the physiological range could participate to sarcopenia development by decreasing muscle function in postmenopausal women.

scholarly journals Comorbidity in hand osteoarthritis: its impact on hand pain and function

2016 ◽  
Vol 24 ◽  
pp. S446-S447
Author(s):  
W. Damman ◽  
R. Liu ◽  
M. Kloppenburg
Keyword(s):  
Hand Osteoarthritis ◽  
Hand Pain ◽  
And Function

scholarly journals Knee Pain Patterns and Associations with Pain and Function in Persons with or at Risk for Symptomatic Radiographic Osteoarthritis: A Cross-sectional Analysis

2015 ◽  
Vol 42 (12) ◽  
pp. 2398-2403 ◽  
Author(s):  
Daniel L. Riddle ◽  
Mateusz Makowski
Keyword(s):  
Knee Pain ◽  
Cross Sectional ◽  
Knee Oa ◽  
Womac Function ◽  
Radiographic Osteoarthritis ◽  
Pain Location ◽  
Pain Scores ◽  
Patient Reported ◽  
And Function ◽  
Sectional Analysis

Objective.Knee pain location is routinely assessed in clinical practice. We determined the patterns of patient-reported pain locations for persons with knee osteoarthritis (OA). We also examined associations between knee pain patterns and severity of self-reported pain with activity and self-reported functional status.Methods.The Osteoarthritis Initiative data were used to examine reports of pain location (localized, regional, or global) and type and extent of knee OA. Multivariable ANCOVA models were used to determine associations between the Knee Injury and Osteoarthritis Outcome Survey (KOOS) Pain and the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) Function scales and pain location after adjusting for potential confounding. We also used radar graphs to illustrate pain patterns for various locations and severity of knee OA.Results.Radar graphs of 2696 knees indicated that pain pattern and location and extent of knee OA demonstrate substantial overlap. An interaction between race and pain location was found for WOMAC Function, but not for KOOS Pain scores. Global knee pain was associated (p < 0.001) with substantially worse function (by 6.5 points in African Americans) compared with pain that was localized. Knee pain reported as global was independently associated (p < 0.001) with clinically important lower (worse by 3.9 points) KOOS Pain scores compared with pain that was localized.Conclusion.Pain patterns are not useful for inferring potential location or severity of knee OA in individual patients, but knee pain patterns that are global are independently associated with worse pain and function compared with localized pain, and associations differ for function based on race.

scholarly journals Difference in Diagnosis and Classification of Sarcopenia: A Cross-Sectional Observational Study

2021 ◽  
Author(s):  
Leonardo Augusto Da Costa Teixeira ◽  
Ana Caroline Negreiros Prates ◽  
Franciane Pereira Brant ◽  
Rávylla Rúbia Lima ◽  
Ronaldo Luis Thomasini ◽  
...  
Keyword(s):  
Body Composition ◽  
Older Women ◽  
Dual Energy ◽  
Progressive Reduction ◽  
Cross Sectional ◽  
X Ray ◽  
Diagnosis And Classification ◽  
And Function ◽  
X Ray Absorption

Abstract Background Sarcopenia is characterized by a progressive reduction in muscle mass, strength and function that comes with aging. There is still broad disagreement regarding for understanding and establishment of universal criteria for the screening of sarcopenia. The objective of present study is to assess differences in the diagnosis and classification of sarcopenia by applying six different criteria to the same sample. Methods Study using the criteria proposed by five groups of authors. Body composition was measured by dual-energy X-ray absorption (DXA) using a Lunar DPX densitometer. Results Participated 156 older women. The frequency of sarcopenia varied depending on the criteria used. The above frequencies exhibited statistically significant differences (p = 0.009). Conclusion Diagnosis of sarcopenia in older women varies according to the proposed criteria.

Prevalence of Disability Associated With Head Injury With Loss of Consciousness in Adults in the United States: A Population-Based Study

Neurology ◽  
2021 ◽  
pp. 10.1212/WNL.0000000000012148
Author(s):  
Andrea L.C. Schneider ◽  
Dan Wang ◽  
Rebecca F. Gottesman ◽  
Elizabeth Selvin
Keyword(s):  
Head Injury ◽  
Grip Strength ◽  
Work Productivity ◽  
The United States ◽  
Population Based ◽  
Self Report ◽  
Loss Of Consciousness ◽  
Cross Sectional ◽  
History Of ◽  
The U.S

Objective:To provide nationally representative prevalence estimates of disability associated with prior head injury with loss of consciousness in the U.S. and to examine associations between prior head injury and disability.Methods:Cross-sectional analysis of 7,390 participants aged ≥40 years in the 2011-2014 National Health and Nutrition Examination Surveys (NHANES). Head injury with loss of consciousness was assessed by self-report. Domains of disability were assessed using a standardized structured questionnaire and measured grip strength. Logistic regression models adjusted for demographic, socioeconomic/behavioral, and medical comorbidity variables were used. Multiple imputation was used to account for missing covariate data.Results:Mean age of participants was 58 years, 53% were female, 71% were non-Hispanic white, and 16% had a history of head injury with loss of consciousness. Overall, participants with a history of head injury had higher prevalence of disability in at least one domain of functioning compared to individuals without head injury (47.4% versus 38.6%, p<0.001), with the highest prevalence of disability in the domains of mobility and work productivity. In fully adjusted models, head injury was significantly positively associated with disability in all domains assessed on the standardized questionnaire (all p<0.05), but not with upper extremity grip strength (all p>0.05).Conclusions:47.4% of individuals aged ≥40 years in the U.S with a history of head injury are living with disability in at least one domain of functioning, corresponding to 11.4 million affected individuals. This significant burden of disability suggests that efforts are needed to improve functioning among individuals with head injury.

Association between hand-grip strength and risk of stroke among Mongolian adults: Results from a population-based study

2021 ◽  
Vol 4 (3Suppl) ◽  
pp. 8-16
Author(s):  
Indra Altankhuyag ◽  
Agiimaa Byambaa ◽  
Anujin Tuvshinjargal ◽  
Anar Bayarmunkh ◽  
Tsolmon Jadamba ◽  
...  
Keyword(s):  
Regression Analysis ◽  
Cohort Study ◽  
Grip Strength ◽  
Population Based ◽  
Cross Sectional Study ◽  
Hand Grip Strength ◽  
Binary Logistic Regression Analysis ◽  
Obese People ◽  
Cross Sectional ◽  
Hand Grip

Mongolia ranks third in the world in stroke-related deaths. Loss of skeletal muscle mass and function, known as sarcopenia, is associated with a higher risk of various metabolic disorders such as stroke. Thus, screening of sarcopenia is important. Hand-grip strength (HGS) can be used to predict sarcopenia in the short term. In this cross-sectional study, we used data (n=1180, mean age of 39.2 ± 15.2 and 33.2% males) from the Mon-Timeline cohort study, a multidisciplinary, prospective, population-based cohort study in Mongolia. A digital grip strength dynamometer (TKK 5401 GRIP D; Takei, Japan) was used to measure HGS. We performed binary logistic regression analysis between HGS and stroke risk. Suspected sarcopenia was defined when HGS is less than the 25th percentile of HGS. In this study, 3.3% of all participants had a stroke. The incidence of stroke was significantly higher (5.2% and 1.9%) in people with suspected sarcopenia. According to body composition, the incidence of stroke was more frequent in sarcopenic obese people: 1.3%, 2.4%, 2.8% and 6.2% in normal (non-obese and non-sarcopenic), sarcopenic (non-obese), obese (non-sarcopenic) and sarcopenic obese groups, respectively. In regression analysis, the OR (95% CI) was 2.84 (1.44; 5.59) for sarcopenic compared with non-sarcopenic. The adjustments for age, gender, education, body mass index, waist circumference and hypertensive status attenuated the associations, but lower HGS remained significantly associated with a higher risk of stroke. In conclusion, lower HGS was significantly associated with a higher risk of stroke independent of adiposity and hypertensive status in Mongolian adults.

scholarly journals P1586SARCOPENIA IN HEMODIALYSIS PATIENTS

2020 ◽  
Vol 35 (Supplement_3) ◽  
Author(s):  
Armando Luis Negri ◽  
Ruben Abdala ◽  
Elisa Del Valle ◽  
Pablo Bridoux ◽  
Luciana Gonzalez Paganti ◽  
...  
Keyword(s):  
Grip Strength ◽  
Muscle Mass ◽  
Physical Performance ◽  
Significant Proportion ◽  
Cross Sectional Study ◽  
Dialysis Patients ◽  
Cross Sectional ◽  
Hand Grip ◽  
Hand Dynamometer ◽  
And Function

Abstract Background and Aims Sarcopenia is the loss of skeletal muscle mass and function that occurs with aging. These modifications lead to greater morbidity and mortality as a result of falls, hospitalization, depression and dependence among others. Chronic Kidney disease (CKD) and hemodialysis (HD) produce a favorable environment for the development of sarcopenia. Objective: to study the prevalence of sarcopenia and its different components (muscle mass, strength and physical performance) using EWGSOP 2018 proposed criteria. Method cross-sectional study evaluating 100 adult HD patients. We evaluated: Grip strength (GS) with Jamar Hydraulic Hand Dynamometer (three determinations in the arm without fistula); Appendicular lean mass (ALM) by DXA (GE LUNAR Prodigy Advance) and physical performance: Gait-speed (Time needed to perform a 4-meter walk on a flat surface) and the sit-stand test Results 58 males (M) and 42 females (F). Mean age for M was 54.3 years and 58 years for F. The prevalence of sarcopenia was 18% in the whole group, 10% in M and 20% in F. In M 33% had low GS and 26% low ALM. In M GS correlated with ALM, Albumin and weight p&lt;0.05 (R 2 0.41); ALM correlated with weight r 0.75, height r 0.64 and GS r 0.46 (p&lt;0.05). In F, 27% had low GS, 54% low ALM, and 17% poor physical performance. In F, GS correlated positively with ALM; ALM correlated positively with: weight r 0.78, height r 0.66, GS r 0.59 and sit-stand r 0.40 (p&lt;0.5). Patients with lower grip strength had a higher prevalence of falls in the last year (40% two or more falls) p=0.03. Conclusion A significant proportion of dialysis patients had sarcopenia. Low hand grip strength was associated with a higher prevalence of falls. Recognizing sarcopenia in dialysis patients would allow us to develop strategies to prevent falls and other complications.

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